SELECT TOP (1000) [Source] ,[Taxon] ,[LowValue] ,[HighValue] ,[LowPCile] ,[HighPCile] FROM [DB_A5D9F7_Lassesen].[dbo].[JasonH]

Fusobacteriota Details: NCBI 32066, gram-negative or unknown [phylum]

| Fusobacteraeota| Fusobacteraeota Oren et al. 2015| Fusobacteria| Fusobacteria Garrity and Holt 2001| Fusobacteriota

  1. Oral health: Fusobacteriota species are common inhabitants of the human oral cavity and are part of the oral microbiota. While they are typically commensal and play roles in normal oral microbial communities, certain species, such as Fusobacterium nucleatum, have been implicated in periodontal diseases. Fusobacterium nucleatum can contribute to the formation of dental plaque and biofilms, leading to periodontitis, gingivitis, and other oral health issues. Additionally, Fusobacterium species have been detected in dental abscesses and oral infections.

  2. Systemic infections: Fusobacteriota species, particularly Fusobacterium necrophorum, have been associated with systemic infections such as Lemierre's syndrome. Lemierre's syndrome is a rare but serious condition characterized by septic thrombophlebitis of the internal jugular vein, often following an acute oropharyngeal infection. Fusobacterium necrophorum can spread from the oral cavity or pharynx to deeper tissues and the bloodstream, leading to septicemia and the formation of septic thrombi in the neck veins.

  3. Inflammatory bowel disease (IBD): Emerging research suggests that Fusobacteriota species may play a role in the pathogenesis of inflammatory bowel diseases (IBD), including Crohn's disease and ulcerative colitis. While the exact mechanisms are not fully understood, Fusobacterium species have been detected in the gut mucosa of individuals with IBD, and their presence has been associated with intestinal inflammation and disease severity. However, the causal relationship between Fusobacteriota and IBD requires further investigation.

  4. Colorectal cancer: Fusobacteriota, particularly Fusobacterium nucleatum, has been implicated in the development and progression of colorectal cancer (CRC). Studies have found an association between increased abundance of Fusobacterium nucleatum in colorectal tumors and poorer clinical outcomes in CRC patients. Fusobacterium nucleatum may promote tumorigenesis through various mechanisms, including modulation of the immune response, promotion of inflammation, and interaction with tumor cells. However, the exact role of Fusobacteriota in CRC pathogenesis is still being elucidated.

  5. Other infections: Fusobacteriota species have been implicated in various other infections, including brain abscesses, septic arthritis, respiratory tract infections, and genital infections. Fusobacteriota may act as opportunistic pathogens, particularly in individuals with predisposing factors such as immunodeficiency, trauma, or underlying medical conditions.

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Lab Reporting

Different labs use different software to read the sample. See this post for more details.
One lab may say you have none, another may say you have a lot! - This may be solely due to the software they are using to estimate.
We deem lab specific values using values from the KM method for each specific lab to be the most reliable.

Desired Levels Suggestions for Fusobacteriota

These are values that are computed from lab specific samples (Patent Pending)
LabFrequencyUD-LowUD-HighKM LowKM HighLab LowLab HighMean MedianStandard DeviationBox Plot LowBox Plot High KM Percentile Low KM Percentile High
Other Labs 3.09 0 0 1 36917 0 16160 3099.2 470 6663.7 0 3180 0 %ile 100 %ile
biomesight 47.95 0 30 10 220 0 34098 2541.9 40 16100.1 0 200 0 %ile 92 %ile
thorne 100 45 596 0 394 154.1 114 122.5 38 270 0 %ile 100 %ile
thryve 53.43 0 39 18 264 0 34172 2734 51 16039.8 0 211 10.9 %ile 90.8 %ile
ubiome 18.38 0 23 20 233930 0 64244 8148.5 134 28620.2 0 2358 0 %ile 100 %ile

External Reference Ranges for Fusobacteriota

Fusobacteriota (NCBI 32066) per million
Source of Ranges Low Boundary High Boundary Low Boundary %age High Boundary %age
Medivere 0 30 0 0.003
GanzImmun Diagostics 0 40 0 0.004
Lab Teletest 0 500 0 0.05
XenoGene 0 10000 0 1
Thorne (20/80%ile) 27.11 60.15 0.0027 0.006
Nirvana/CosmosId 200 2500 0.02 0.25
Statistic by Lab Source for Fusobacteriota
These desired values are reported from the lab reports
Lab Frequency Seen Average Standard Deviation Sample Count Lab Samples
AmericanGut 13.333 %   0.029 %  0.032 % 2.0 15
BiomeSight 50.663 %   0.281 %  1.772 % 1451.0 2864
BiomeSightRdp 15.625 %   0.002 %  0.001 % 5.0 32
bugspeak 100 %   0.01 %  % 1.0 1
CerbaLab 100 %   0.042 %  0.02 % 3.0 3
CosmosId 6.25 %   0.009 %  0.009 % 2.0 32
custom 52.542 %   0.764 %  0.785 % 31.0 59
es-xenogene 96.552 %   0.117 %  0.135 % 28.0 29
GanzimmunDiag 100 %   0.009 %  0 % 3.0 3
Medivere 85.714 %   0.026 %  0.037 % 6.0 7
Microba 10.714 %   0.015 %  0.002 % 3.0 28
SequentiaBiotech 19.444 %   0.641 %  1.349 % 7.0 36
Thorne 85.556 %   0.011 %  0.011 % 77.0 90
Thryve 53.29 %   0.27 %  1.61 % 737.0 1383
Tiny 100 %   0.002 %  % 1.0 1
uBiome 18.308 %   0.815 %  2.862 % 145.0 792

Symptoms Associated with Fusobacteriota From Citizen Science Studies

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MagnitudeImpactSymptom

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Data Contradictions β€” Limits of Certainity

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General Substance Specific Substance Effect
Food (excluding seasonings) barley 1 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings) broccoli 2 Studies recorded. The consensus is Decreases👶👪, Click for details.
Food (excluding seasonings) navy bean 1 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings) whole-grain barley 1 Studies recorded. The consensus is Decreases👶, Click for details.
Herb or Spice berberine 1 Studies recorded. The consensus is Increases👶, Click for details.
Miscellaneous, food additives, and other odd items isovaleric acid(fatty acid) 1 Studies recorded. The consensus is Increases👶, Click for details.
Prebiotics and similar ß-glucan 1 Studies recorded. The consensus is Decreases👶, Click for details.
Prescription - Other moviprep (prescription) 1 Studies recorded. The consensus is Increases👶, Click for details.
Probiotics bacillus amyloliquefaciens (probiotic) 1 Studies recorded. The consensus is Increases👪, Click for details.
Probiotics bifidobacterium bifidum (probiotics) 1 Studies recorded. The consensus is Decreases👶, Click for details.
Probiotics enterococcus faecium (probiotic) 1 Studies recorded. The consensus is Decreases👶, Click for details.
Probiotics lactobacillus sakei (probiotics) 1 Studies recorded. The consensus is Increases👶, Click for details.
Sugar and similar sialic acid 1 Studies recorded. The consensus is Increases👶, Click for details.
Vitamins, Minerals and similar Vitamin B 1 Studies recorded. The consensus is Increases👶, Click for details.
Vitamins, Minerals and similar Vitamin C (ascorbic acid) 1 Studies recorded. The consensus is Increases👶, Click for details.
Vitamins, Minerals and similar Vitamin E 1 Studies recorded. The consensus is Increases👶, Click for details.

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