Aggregatibacter Details: NCBI 416916, gram-negative or unknown [genus]
| Aggregatibacter| Aggregatibacter Norskov-Lauritsen and Kilian 2006
Oral Pathogen: Aggregatibacter actinomycetemcomitans is considered an oral pathogen and is often associated with periodontal diseases. It can colonize the periodontal pockets around teeth and contribute to the development of periodontitis, a severe form of gum disease.
Periodontal Diseases: Aggregatibacter actinomycetemcomitans has been implicated in various periodontal diseases, including aggressive periodontitis. In aggressive periodontitis, there is a rapid loss of supporting structures around the teeth, leading to tooth mobility and potential tooth loss.
Endocarditis: While less common, Aggregatibacter actinomycetemcomitans has been associated with infective endocarditis, an infection of the heart valves. Individuals with pre-existing heart conditions may be at a higher risk.
Systemic Health: The presence of periodontal pathogens, including Aggregatibacter actinomycetemcomitans, has been studied in relation to systemic health. Some studies have explored potential links between periodontal diseases and conditions such as cardiovascular disease and diabetes. However, the nature of these associations is complex and may involve various factors.
Antibiotic Resistance: Some strains of Aggregatibacter actinomycetemcomitans may exhibit antibiotic resistance, which can impact treatment strategies for infections caused by this bacterium.
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Other Sources for more information:
- Immune Epitope Database
- The NCBI taxonomy database
- UniProt
- Immune Epitope Taxonomy Database (IEDB)
- AI Engines For more Details: Perplexity Kagi Labs You
 Statistics
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NCBI | Data Punk | End Products Produced |
Lab Reporting
Different labs use different software to read the sample. See this post for more details.
One lab may say you have none, another may say you have a lot! - This may be solely due to the software they are using to estimate.
We deem lab specific values using values from the KM method for each specific lab to be the most reliable.
Desired Levels Suggestions for Aggregatibacter
- Frequency - how often do samples show this bacteria
- UD - An alternative statistical algorithm (which factors in the frequency)
- Kaltoft-Moldrup Heuristic Using uploaded data
- Lab Low and High are calculated using the formula that most labs use: Mean - 2 Standard Deviation to Mean + 2 Standard Deviation
| Lab | Frequency | UD-Low | UD-High | KM Low | KM High | Lab Low | Lab High | Mean | Median | Standard Deviation | Box Plot Low | Box Plot High | KM Percentile Low | KM Percentile High |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Other Labs | 1.15 | 5 | 4901 | 0 | 2142 | 273.8 | 30 | 953.2 | 3 | 149 | 0 %ile | 100 %ile | ||
| biomesight | 24.1 | 0 | 20 | 10 | 3120 | 0 | 2143 | 318.4 | 60 | 930.9 | 0 | 320 | 0 %ile | 98.1 %ile |
| thorne | 89.66 | 1 | 21417 | 0 | 9067 | 841.8 | 6 | 4196.7 | 0 | 24 | 0 %ile | 100 %ile | ||
| thryve | 16.52 | 0 | 9 | 15 | 4416 | 0 | 835 | 98.1 | 30 | 376.1 | 8 | 104 | 8 %ile | 100 %ile |
| ubiome | 21.67 | 0 | 24 | 18 | 18250 | 0 | 4976 | 802.4 | 135 | 2129.4 | 0 | 745 | 0 %ile | 100 %ile |
External Reference Ranges for Aggregatibacter
| Source of Ranges | Low Boundary | High Boundary | Low Boundary %age | High Boundary %age |
|---|---|---|---|---|
| Thorne (20/80%ile) | 2.2 | 7.68 | 0.0002 | 0.0008 |
Statistic by Lab Source for Aggregatibacter
| Lab | Frequency Seen | Average | Standard Deviation | Sample Count | Lab Samples |
|---|---|---|---|---|---|
| AmericanGut | 6.667 % | 0.49 % | % | 1.0 | 15 |
| BiomeSight | 25.085 % | 0.035 % | 0.121 % | 742.0 | 2958 |
| BiomeSightRdp | 43.75 % | 0.004 % | 0.005 % | 14.0 | 32 |
| CerbaLab | 66.667 % | 0.001 % | 0 % | 2.0 | 3 |
| CosmosId | 9.375 % | 0.017 % | 0.027 % | 3.0 | 32 |
| custom | 9.836 % | 0.001 % | 0.001 % | 6.0 | 61 |
| es-xenogene | 3.448 % | 0.009 % | % | 1.0 | 29 |
| Medivere | 71.429 % | 0.006 % | 0.007 % | 5.0 | 7 |
| SequentiaBiotech | 5.556 % | 0.037 % | 0.02 % | 2.0 | 36 |
| Thorne | 75.269 % | 0.033 % | 0.256 % | 70.0 | 93 |
| Thryve | 18.917 % | 0.008 % | 0.032 % | 262.0 | 1385 |
| uBiome | 21.591 % | 0.08 % | 0.213 % | 171.0 | 792 |
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Foods Containing the Aggregatibacter bacteria
Data comes from FoodMicrobionet. For the meaning of weight, see that site. The bacteria does not need to be alive to have an effect.
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