Filifactor Details: NCBI 44259, gram-negative or unknown [genus]

| Filifactor| Filifactor Collins et al. 1994

1. Oral health: Filifactor species are part of the normal oral microbiota, where they contribute to the formation of dental plaque and biofilms. While they are generally considered commensal bacteria, Filifactor species have been associated with periodontal diseases such as gingivitis and periodontitis. These bacteria can proliferate in the gingival sulcus and periodontal pockets, where they contribute to inflammation, tissue destruction, and bone loss characteristic of periodontal diseases.

2. Respiratory infections: Filifactor species have been detected in the respiratory tract and have been associated with respiratory infections such as pneumonia and chronic obstructive pulmonary disease (COPD). While their exact role in respiratory infections is not fully understood, Filifactor species may contribute to airway inflammation, mucus production, and exacerbations of respiratory conditions. Further research is needed to elucidate the mechanisms by which Filifactor species interact with the respiratory mucosa and contribute to respiratory infections.

3. Systemic diseases: There is growing evidence linking oral bacteria, including Filifactor species, to systemic diseases such as cardiovascular disease, diabetes, and rheumatoid arthritis. Oral bacteria can enter the bloodstream through oral mucosal lesions, dental procedures, or periodontal pockets, leading to bacteremia and systemic dissemination. Once in the bloodstream, these bacteria may contribute to systemic inflammation, endothelial dysfunction, and the progression of systemic diseases. While the exact role of Filifactor species in systemic diseases requires further investigation, their presence in the oral cavity may have implications for systemic health.

4. Antibiotic resistance: Some species within the genus Filifactor have been reported to exhibit antibiotic resistance, which may complicate treatment of infections caused by these bacteria. Antibiotic-resistant strains of Filifactor species have been isolated from dental plaque and periodontal pockets, highlighting the importance of antimicrobial stewardship and surveillance of antibiotic resistance in oral bacteria.

A lot more information is available when you are logged in and raise the display level

Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

More Information

Statistics

NCBI

Data Punk

End Products Produced

Lab Reporting

Different labs use different software to read the sample. See this post for more details.
One lab may say you have none, another may say you have a lot! - This may be solely due to the software they are using to estimate.
We deem lab specific values using values from the KM method for each specific lab to be the most reliable.

Desired Levels Suggestions for Filifactor

• Frequency - how often do samples show this bacteria
• UD - An alternative statistical algorithm (which factors in the frequency)
• Kaltoft-Moldrup Heuristic Using uploaded data
• Lab Low and High are calculated using the formula that most labs use: Mean - 2 Standard Deviation to Mean + 2 Standard Deviation

These are values that are computed from lab specific samples (Patent Pending)

Lab	Frequency	UD-Low	UD-High	KM Low	KM High	Lab Low	Lab High	Mean	Median	Standard Deviation	Box Plot Low	Box Plot High	KM Percentile Low	KM Percentile High
Other Labs	1.32			4	669	0	426	155.9	122	137.9	37	287	0 %ile	100 %ile
biomesight	28.25	0	20	10	110	0	7155	276.3	40	3509.6	0	120	0 %ile	89.6 %ile
thorne	100			3	67	0	54	21.5	16	16.4	4	34	0 %ile	100 %ile
thryve	32.31	0	19	1	89	0	454	69.9	31	196	9	103	0 %ile	90.7 %ile

External Reference Ranges for Filifactor

Filifactor (NCBI 44259) per million

Source of Ranges	Low Boundary	High Boundary	Low Boundary %age	High Boundary %age
Thorne (20/80%ile)	4.15	11.67	0.0004	0.0012

Statistic by Lab Source for Filifactor

These desired values are reported from the lab reports

Lab	Frequency Seen	Average	Standard Deviation	Sample Count	Lab Samples
BiomeSight	30.105 %	0.026 %	0.307 %	892.0	2963
BiomeSightRdp	3.226 %	0.001 %	%	1.0	31
CerbaLab	66.667 %	0.007 %	0.008 %	2.0	3
custom	14.754 %	0.007 %	0.003 %	9.0	61
es-xenogene	41.379 %	0.007 %	0.003 %	12.0	29
SequentiaBiotech	50 %	0.022 %	0.014 %	18.0	36
Thorne	83.654 %	0.001 %	0.001 %	87.0	104
Thryve	32.158 %	0.007 %	0.018 %	447.0	1390

To see medical conditions associated you may be logged in

And display level must be raised above public.

I would like to know what can change the quality that I have

• If I want to know that a substance also changes, then I just click on it
• If I want to know which study this information comes from, then I just clink in increases or decreases

Data Contradictions — Limits of Certainity

To get the list of studies, you must be logged in and raise your display level.

🧙? Search Hints:

General Substance	Specific Substance	Effect
Amino Acid and similar	l-proline	1 Studies recorded. The consensus is Decreases📓, Click for details.
Antibiotics, Antivirals etc	doxycycline (antibiotic)s[CFS]	1 Studies recorded. The consensus is Decreases📓, Click for details.
Antibiotics, Antivirals etc	metronidazole (antibiotic)s[CFS]	1 Studies recorded. The consensus is Decreases📓, Click for details.
Antibiotics, Antivirals etc	minocycline (antibiotic)s[CFS]	1 Studies recorded. The consensus is Decreases📓, Click for details.
Antibiotics, Antivirals etc	Rapamycin	1 Studies recorded. The consensus is Decreases📓, Click for details.
Common Supplements	Tributyrin	1 Studies recorded. The consensus is Decreases📓, Click for details.
Diet Style	high sugar diet	1 Studies recorded. The consensus is Decreases📓, Click for details.
Diet Style	high-fat diets	1 Studies recorded. The consensus is Decreases📓, Click for details.
Diet Style	Olive Oil	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	Cranberry	1 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	cranberry bean flour	2 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	ku ding cha tea	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	Nicotine, Nicotine Patch	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	plantain bananas	1 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	rare meat	1 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	safflower oil	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	tea	1 Studies recorded. The consensus is Decreases📓, Click for details.
Herb or Spice	berberine	1 Studies recorded. The consensus is Increases📓, Click for details.
Herb or Spice	Carthamus tinctorius L,Safflower	1 Studies recorded. The consensus is Decreases📓, Click for details.
Herb or Spice	oregano (origanum vulgare, oil) |	1 Studies recorded. The consensus is Increases📓, Click for details.
Miscellaneous, food additives, and other odd items	bile (acid/salts)	2 Studies recorded. The consensus is Decreases📓, Click for details.
Miscellaneous, food additives, and other odd items	Bismuth Salts	2 Studies recorded. The consensus is Decreases📓, Click for details.
Miscellaneous, food additives, and other odd items	Polyethylene glycol	1 Studies recorded. The consensus is Decreases📓, Click for details.
Prebiotics and similar	fructo-oligosaccharides (prebiotic)	1 Studies recorded. The consensus is Decreases📓, Click for details.
Prebiotics and similar	resistant starch	1 Studies recorded. The consensus is Decreases📓, Click for details.
Prescription - Other	metformin (prescription)	1 Studies recorded. The consensus is Decreases📓, Click for details.
Probiotics	bifidobacterium longum,lactobacillus helveticus (probiotics)	1 Studies recorded. The consensus is Decreases📓, Click for details.
Probiotics	lactobacillus reuteri (probiotics)	1 Studies recorded. The consensus is Decreases📓, Click for details.
Sugar and similar	d-trehalose (sugar)	1 Studies recorded. The consensus is Increases📓, Click for details.
Sugar and similar	glucose (sugar)	1 Studies recorded. The consensus is Increases📓, Click for details.
Sugar and similar	saccharin	1 Studies recorded. The consensus is Increases📓, Click for details.

Foods Containing the Filifactor bacteria

Data comes from FoodMicrobionet. For the meaning of weight, see that site. The bacteria does not need to be alive to have an effect.

Passito wine Weight: 0.0645 Tej, Ethiopia Weight: 0.0294 Palm wine Weight: 0.003876

---