Mitsuokella Details: NCBI 52225, gram-negative or unknown [genus]

| Mitsuokella| Mitsuokella Shah and Collins 1983

1. Commensal gut bacterium: Mitsuokella is considered a commensal bacterium, meaning it typically resides in the gut microbiota of humans and animals without causing harm under normal conditions. Commensal bacteria play important roles in maintaining gut health, such as aiding in digestion, producing beneficial metabolites, and modulating the immune system.

2. Fermentation: Like other members of the family Veillonellaceae, Mitsuokella is known for its fermentative metabolism. It can metabolize various dietary carbohydrates, such as lactate, succinate, and pyruvate, producing short-chain fatty acids (SCFAs) as metabolic byproducts. SCFAs, particularly acetate, propionate, and butyrate, serve as an energy source for colonic epithelial cells and have been associated with various health benefits, including gut barrier function, immune regulation, and anti-inflammatory effects.

3. Role in gut dysbiosis: While Mitsuokella is generally considered part of the normal gut microbiota, alterations in its abundance or composition may occur in certain disease states or conditions associated with gut dysbiosis. Dysbiosis refers to an imbalance in the gut microbial community that is linked to various gastrointestinal disorders, such as inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), and colorectal cancer. Changes in the relative abundance of Mitsuokella and other gut bacteria may contribute to the pathogenesis or progression of these conditions.

4. Potential probiotic properties: Some strains of Mitsuokella may exhibit probiotic properties, meaning they have the potential to confer health benefits when consumed in adequate amounts. Probiotics are live microorganisms that, when administered in adequate amounts, confer a health benefit on the host. While research on the probiotic potential of Mitsuokella is limited, certain strains may possess characteristics that make them suitable candidates for use as probiotics, such as acid and bile tolerance, adherence to intestinal epithelial cells, and antimicrobial activity against pathogens.

5. Metabolic disorders and obesity: Emerging evidence suggests that alterations in the gut microbiota composition, including changes in the abundance of Mitsuokella and other bacteria, may be associated with metabolic disorders such as obesity and type 2 diabetes. While the specific role of Mitsuokella in metabolic health is not well-understood, its interactions with other gut microbes and host physiology may influence metabolic processes and contribute to the development or progression of metabolic diseases.

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Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

More Information

Statistics

NCBI

Data Punk

End Products Produced

Lab Reporting

Different labs use different software to read the sample. See this post for more details.
One lab may say you have none, another may say you have a lot! - This may be solely due to the software they are using to estimate.
We deem lab specific values using values from the KM method for each specific lab to be the most reliable.

Desired Levels Suggestions for Mitsuokella

• Frequency - how often do samples show this bacteria
• UD - An alternative statistical algorithm (which factors in the frequency)
• Kaltoft-Moldrup Heuristic Using uploaded data
• Lab Low and High are calculated using the formula that most labs use: Mean - 2 Standard Deviation to Mean + 2 Standard Deviation

These are values that are computed from lab specific samples (Patent Pending)

Lab	Frequency	UD-Low	UD-High	KM Low	KM High	Lab Low	Lab High	Mean	Median	Standard Deviation	Box Plot Low	Box Plot High	KM Percentile Low	KM Percentile High
Other Labs	0.79			10	16556	0	12587	2272.9	80	5262.2	10	16556	0 %ile	100 %ile
biomesight	39.77	0	20	10	6170	0	7176	546.9	40	3382.4	0	140	3.6 %ile	97.7 %ile
thryve	8.12	0	0	1	15757	0	7028	1439.7	34	2851.2	2	2538	0 %ile	100 %ile
ubiome	2.28			23	214652	0	134061	28783.6	7828	53712.9	23	214652	0 %ile	100 %ile

External Reference Ranges for Mitsuokella

Mitsuokella (NCBI 52225) per million

Source of Ranges	Low Boundary	High Boundary	Low Boundary %age	High Boundary %age

Statistic by Lab Source for Mitsuokella

These desired values are reported from the lab reports

Lab	Frequency Seen	Average	Standard Deviation	Sample Count	Lab Samples
BiomeSight	42.563 %	0.057 %	0.362 %	1262.0	2965
BiomeSightRdp	61.29 %	0.039 %	0.081 %	19.0	31
bugspeak	100 %	0.005 %	%	1.0	1
CosmosId	3.125 %	0.003 %	%	1.0	32
custom	3.279 %	0.052 %	0.067 %	2.0	61
SequentiaBiotech	5.556 %	1.656 %	0 %	2.0	36
Thryve	7.615 %	0.162 %	0.302 %	106.0	1392
uBiome	2.273 %	2.878 %	5.371 %	18.0	792

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Data Contradictions — Limits of Certainity

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General Substance	Specific Substance	Effect
Diet Style	moderate-protein moderate-carbohydrate	1 Studies recorded. The consensus is Increases👶, Click for details.
flavonoids, polyphenols etc	chestnut tannins	1 Studies recorded. The consensus is Decreases👶, Click for details.
flavonoids, polyphenols etc	quebracho	1 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings)	Nicotine, Nicotine Patch	1 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings)	whey	1 Studies recorded. The consensus is Increases👶, Click for details.
Herb or Spice	ginko	1 Studies recorded. The consensus is Increases📓, Click for details.
Prebiotics and similar	arabinogalactan (prebiotic)	1 Studies recorded. The consensus is Increases👶, Click for details.
Prebiotics and similar	inulin (prebiotic)	1 Studies recorded. The consensus is Increases👶, Click for details.
Prebiotics and similar	oligosaccharides (prebiotic)	1 Studies recorded. The consensus is Increases👶, Click for details.
Probiotics	lactobacillus reuteri (probiotics)	1 Studies recorded. The consensus is Increases👶, Click for details.

Foods Containing the Mitsuokella bacteria

Data comes from FoodMicrobionet. For the meaning of weight, see that site. The bacteria does not need to be alive to have an effect.

Trentingrana Cheese (Italy) Weight: 0.1367 Firm - ripened cheeses Unpasteurised Cow Weight: 0.1159 Lard Farm Weight: 0.01018

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