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Citizen Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.

SymptomImpactPredictor of Bacteria Shift
Age: 60-70Worsen1.7
Autism: Official DiagnosisImproves-3.2
Autonomic Manifestations: palpitationsWorsen2.93
Blood Type: A PositiveImproves-1.86
Blood Type: O PositiveImproves-3.09
Comorbid-Mouth: Dry MouthWorsen3.03
Comorbid-Mouth: TMJ / Dysfunction of the temporomandibular joint syndromeWorsen1.62
Comorbid: Constipation and Explosions (not diarrohea)Worsen1.93
Comorbid: High AnxietyImproves-2.81
Comorbid: Histamine or Mast Cell issuesWorsen2.32
Comorbid: Inflammatory bowel disease Improves-3.65
Comorbid: MigraineImproves-1.86
Comorbid: Mold Sensitivity / ExposureWorsen1.82
Comorbid: Snoring (NOT Sleep ApneaImproves-2.81
DePaul University Fatigue Questionnaire : AllergiesImproves-2.69
DePaul University Fatigue Questionnaire : Anxiety/tensionImproves-2.69
DePaul University Fatigue Questionnaire : DepressionImproves-2.93
DePaul University Fatigue Questionnaire : Difficulty staying asleepImproves-2.93
DePaul University Fatigue Questionnaire : FatigueImproves-4.31
DePaul University Fatigue Questionnaire : Forgetting what you are trying to sayImproves-2.69
DePaul University Fatigue Questionnaire : Impaired Memory & concentrationImproves-4.3
DePaul University Fatigue Questionnaire : Unrefreshing Sleep, that is waking up feeling tired Improves-4.12
DePaul University Fatigue Questionnaire : Walking up early in the morning (e.g. 3AM)Improves-2.71
General: FatigueWorsen2.87
General: HeadachesWorsen1.62
General: Myalgia (pain)Worsen2.81
Immune Manifestations: Alcohol IntolerantWorsen1.62
Immune Manifestations: BloatingWorsen2.87
Immune Manifestations: ConstipationWorsen2.87
Infection: Epstein-Barr virusImproves-1.83
Infection: Human Herpesvirus 6 (HHV6)Worsen1.75
Joint: Stiffness and swellingWorsen1.7
Neuroendocrine Manifestations: Excessive adrenalineWorsen1.68
Neuroendocrine Manifestations: Paraesthesia (tingling burning of skin)Improves-2.81
Neuroendocrine Manifestations: sweating episodesImproves-2.2
Neuroendocrine: Alcohol intoleranceWorsen1.7
Neuroendocrine: Lack of appetiteWorsen2.87
Neurological-Vision: Blurred VisionWorsen2.93
Neurological-Vision: inability to focus eye/visionWorsen2.87
Neurological: Difficulty readingImproves-2.81
Neurological: fasciculations Worsen3.16
Neurological: Joint hypermobilityImproves-1.83
Neurological: Slowed speechWorsen1.61
Official Diagnosis: Allergic Rhinitis (Hay Fever)Improves-2.47
Official Diagnosis: Mast Cell DysfunctionImproves-2.49
Onset: 2010-2020Worsen2.87
Pain: Sensitivity to painImproves-1.83
Sleep: Daytime drowsinessWorsen2.87
Sleep: Problems staying asleepWorsen3.1
Sleep: Waking up early in the morning (e.g. 3 AM)Worsen1.7

Published Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is according to the microbiome shifts reported in studies. Clinical studies may show different results

SymptomImpactPredictor of Bacteria Shift
ADHDImproves-3.98
Allergic Rhinitis (Hay Fever)Improves-1.62
AllergiesWorsen2.97
Alzheimer's diseaseImproves-3.8
Amyotrophic lateral sclerosis (ALS) Motor NeuronImproves-2.25
Ankylosing spondylitisImproves-4.11
AtherosclerosisWorsen3.79
AutismImproves-0.95
Barrett esophagus cancerImproves-2.93
Bipolar DisorderWorsen2.58
Brain TraumaImproves-2.81
CarcinomaWorsen2.81
Celiac DiseaseWorsen2.81
Cerebral PalsyWorsen2.82
Chronic Fatigue SyndromeImproves-2.97
Chronic Kidney DiseaseImproves-1.86
Colorectal CancerImproves-4.9
Coronary artery disease Worsen2.67
COVID-19Worsen2.93
Crohn's DiseaseImproves-1.89
DepressionImproves-4.4
EpilepsyImproves-3.64
FibromyalgiaImproves-4.18
Functional constipation / chronic idiopathic constipationImproves-2.97
gallstone disease (gsd)Worsen2.97
Graves' diseaseWorsen2.97
High Blood PressureWorsen2.33
Histamine Issues From UbiomeWorsen1.61
Hyperlipidemia (High Blood Fats)Worsen3.98
IgA nephropathy (IgAN)Worsen0.15
Irritable Bowel SyndromeImproves-3.91
Liver CirrhosisWorsen4.55
ME/CFS with IBSImproves-2.97
ME/CFS without IBSImproves-1.7
Mood DisordersImproves-2.97
Multiple SclerosisImproves-4.72
Multiple system atrophy (MSA)Improves-2.92
neuropsychiatric disorders (PANDAS, PANS)Improves-2.97
Nonalcoholic Fatty Liver Disease (nafld) NonalcoholicWorsen2.97
ObesityImproves-4.53
OsteoporosisWorsen2.97
Parkinson's DiseaseImproves-5.08
PsoriasisWorsen2.97
rheumatoid arthritis (RA),Spondyloarthritis (SpA)Improves-3.45
SchizophreniaImproves-3.38
Sjögren syndromeWorsen2.97
Stress / posttraumatic stress disorderImproves-3.16
Systemic Lupus ErythematosusWorsen3.55
Type 1 DiabetesWorsen2.82
Type 2 DiabetesImproves-4.38
Ulcerative colitisWorsen2.02

Bacteria Impacted

Suggest a missed study:

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

📓 - direct citation | 👪 - Impacts Parent Taxa | 👶 - Impacts Child Taxa | 🧙 - Inferred
Taxonomy Rank Effect Citations
Christensenellaceae family Decreases 📓 Source Study
Coriobacteriaceae family Decreases 📓 Source Study
Desulfovibrionaceae family Decreases 📓 Source Study
Rikenellaceae family Decreases 📓 Source Study
Ruminococcaceae family Decreases 📓 Source Study
Sutterellaceae family Decreases 📓 Source Study
Alistipes genus Decreases 📓 Source Study
Anaerotruncus genus Decreases 📓 Source Study
Christensenella genus Decreases 📓 Source Study
Desulfovibrio genus Decreases 📓 Source Study
Gordonibacter genus Decreases 📓 Source Study
Parasutterella genus Decreases 📓 Source Study
Acetanaerobacterium genus Decreases 👪 Source Study
Acetobacteroides genus Decreases 👪 Source Study
Agathobaculum genus Decreases 👪 Source Study
Anaerocella genus Decreases 👪 Source Study
Anaerofilum genus Decreases 👪 Source Study
Anaeromassilibacillus genus Decreases 👪 Source Study
Angelakisella genus Decreases 👪 Source Study
Bittarella genus Decreases 👪 Source Study
Candidatus Soleaferrea genus Decreases 👪 Source Study
Caproiciproducens genus Decreases 👪 Source Study
Christensenella genus Decreases 👪 Source Study
Coriobacterium genus Decreases 👪 Source Study
Desulfobaculum genus Decreases 👪 Source Study
Desulfohalovibrio genus Decreases 👪 Source Study
Duodenibacillus genus Decreases 👪 Source Study
Enorma genus Decreases 👪 Source Study
Ethanoligenens genus Decreases 👪 Source Study
Flavonifractor genus Decreases 👪 Source Study
Fournierella genus Decreases 👪 Source Study
Gemmiger genus Decreases 👪 Source Study
Gorbachella genus Decreases 👪 Source Study
Hydrogenoanaerobacterium genus Decreases 👪 Source Study
Lawsonia genus Decreases 👪 Source Study
Mucinivorans genus Decreases 👪 Source Study
Negativibacillus genus Decreases 👪 Source Study
Neglecta genus Decreases 👪 Source Study
Papillibacter genus Decreases 👪 Source Study
Parvibacter genus Decreases 👪 Source Study
Phocea genus Decreases 👪 Source Study
Pseudodesulfovibrio genus Decreases 👪 Source Study
Pseudoflavonifractor genus Decreases 👪 Source Study
Rikenella genus Decreases 👪 Source Study
Ruthenibacterium genus Decreases 👪 Source Study
Senegalimassilia genus Decreases 👪 Source Study
Sporobacter genus Decreases 👪 Source Study
Turicimonas genus Decreases 👪 Source Study
Bacteroidota phylum Decreases 📓 Source Study
Firmicutes phylum Increases 📓 Source Study
Alistipes ihumii species Decreases 👪 Source Study
Alistipes inops species Decreases 👪 Source Study
Alistipes massiliensis species Decreases 👪 Source Study
Alistipes obesi species Decreases 👪 Source Study
Alistipes onderdonkii species Decreases 👪 Source Study
Alistipes senegalensis Mishra et al. 2012 species Decreases 👪 Source Study
Alistipes sp. species Decreases 👪 Source Study
Alistipes sp. cv1 species Decreases 👪 Source Study
Alistipes sp. DJF_B185 species Decreases 👪 Source Study
Alistipes sp. EBA6-25cl2 species Decreases 👪 Source Study
Alistipes sp. HGB5 species Decreases 👪 Source Study
Alistipes sp. Marseille-P5997 species Decreases 👪 Source Study
Alistipes sp. NML05A004 species Decreases 👪 Source Study
Alistipes sp. RMA 9912 species Decreases 👪 Source Study
Alistipes sp. S457 species Decreases 👪 Source Study
Alistipes timonensis species Decreases 👪 Source Study
Anaerotruncus colihominis species Decreases 👪 Source Study
Anaerotruncus rubiinfantis species Decreases 👪 Source Study
Anaerotruncus sp. species Decreases 👪 Source Study
Anaerotruncus sp. NML 070203 species Decreases 👪 Source Study
ATCC 33405 species Decreases 👪 Source Study
Christensenella minuta species Decreases 👪 Source Study
Christensenella sp. species Decreases 👪 Source Study
Christensenella sp. Marseille-P3954 species Decreases 👪 Source Study
Desulfomonas oviles species Decreases 👪 Source Study
Desulfovibrio alaskensis species Decreases 👪 Source Study
Desulfovibrio aminophilus species Decreases 👪 Source Study
Desulfovibrio biadhensis species Decreases 👪 Source Study
Desulfovibrio butyratiphilus species Decreases 👪 Source Study
Desulfovibrio cuneatus species Decreases 👪 Source Study
Desulfovibrio desulfuricans species Decreases 👪 Source Study
Desulfovibrio fairfieldensis species Decreases 👪 Source Study
Desulfovibrio ferrophilus species Decreases 👪 Source Study
Desulfovibrio frigidus species Decreases 👪 Source Study
Desulfovibrio fructosivorans species Decreases 👪 Source Study
Desulfovibrio gabonensis species Decreases 👪 Source Study
Desulfovibrio gigas species Decreases 👪 Source Study
Desulfovibrio hydrothermalis species Decreases 👪 Source Study
Desulfovibrio idahonensis species Decreases 👪 Source Study
Desulfovibrio inopinatus species Decreases 👪 Source Study
Desulfovibrio intestinalis species Decreases 👪 Source Study
Desulfovibrio legallii species Decreases 👪 Source Study
Desulfovibrio litoralis species Decreases 👪 Source Study
Desulfovibrio magneticus species Decreases 👪 Source Study
Desulfovibrio marinus species Decreases 👪 Source Study
Desulfovibrio marrakechensis species Decreases 👪 Source Study
Desulfovibrio mexicanus species Decreases 👪 Source Study
Desulfovibrio oxyclinae species Decreases 👪 Source Study
Desulfovibrio piger species Decreases 👪 Source Study
Desulfovibrio psychrotolerans species Decreases 👪 Source Study
Desulfovibrio salexigens species Decreases 👪 Source Study
Desulfovibrio senezii species Decreases 👪 Source Study
Desulfovibrio sp. species Decreases 👪 Source Study
Desulfovibrio sp. 3_1_syn3 species Decreases 👪 Source Study
Desulfovibrio sp. 6_1_46AFAA species Decreases 👪 Source Study
Desulfovibrio sp. ABHU1SB species Decreases 👪 Source Study
Desulfovibrio sp. ABHU2SB species Decreases 👪 Source Study
Desulfovibrio sp. canine oral taxon 070 species Decreases 👪 Source Study
Desulfovibrio sp. D4 species Decreases 👪 Source Study
Desulfovibrio sp. F1 species Decreases 👪 Source Study
Desulfovibrio sp. FW1012B species Decreases 👪 Source Study
Desulfovibrio sp. G11 species Decreases 👪 Source Study
Desulfovibrio sp. J01 species Decreases 👪 Source Study
Desulfovibrio sp. LNB1 species Decreases 👪 Source Study
Desulfovibrio vietnamensis species Decreases 👪 Source Study
Desulfovibrio vulgaris species Decreases 👪 Source Study
DSM 102344 species Decreases 👪 Source Study
environmental samples species Decreases 👪 Source Study
Gordonibacter massiliensis species Decreases 👪 Source Study
Gordonibacter pamelaeae species Decreases 👪 Source Study
Gordonibacter sp. species Decreases 👪 Source Study
Gordonibacter urolithinfaciens species Decreases 👪 Source Study
Parasutterella excrementihominis species Decreases 👪 Source Study
Parasutterella secunda species Decreases 👪 Source Study
Parasutterella sp. species Decreases 👪 Source Study

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