AI Engines For more Details: Perplexity Kagi Labs You
Contraception: Norgestrel, when combined with estrogen, is commonly used in oral contraceptive pills (OCPs) to prevent pregnancy. It works primarily by inhibiting ovulation (the release of an egg from the ovary) and thickening the cervical mucus, making it more difficult for sperm to reach the egg. Additionally, it may alter the uterine lining to prevent implantation of a fertilized egg.
Hormone Replacement Therapy (HRT): Norgestrel, along with estrogen, is used in HRT for women who are experiencing menopausal symptoms such as hot flashes, vaginal dryness, and mood changes. HRT helps to alleviate these symptoms by replacing the hormones that the body no longer produces in adequate amounts after menopause. Norgestrel can help protect the uterus from the potential adverse effects of estrogen therapy, such as endometrial hyperplasia (overgrowth of the uterine lining), when used in combination with estrogen.
Menstrual Disorders: In some cases, norgestrel may be prescribed to regulate menstrual cycles and treat certain menstrual disorders, such as irregular or heavy menstrual bleeding (menorrhagia). It can help stabilize the hormonal fluctuations that contribute to these issues and promote more regular and lighter menstrual periods.
Endometriosis: Norgestrel-containing contraceptive pills may be used off-label to manage symptoms of endometriosis, a condition in which the tissue that normally lines the inside of the uterus grows outside the uterus, leading to pelvic pain and infertility. By suppressing ovulation and reducing menstrual flow, norgestrel can help alleviate pain and inflammation associated with endometriosis.
Polycystic Ovary Syndrome (PCOS): Norgestrel-containing contraceptive pills may also be used off-label to manage symptoms of PCOS, a hormonal disorder characterized by irregular menstrual periods, excessive hair growth, acne, and infertility. By regulating menstrual cycles and reducing androgen levels, norgestrel can help improve symptoms of PCOS, although it is not specifically approved for this indication.
| Rank | Probiotic | Impact |
|---|---|---|
| species | Akkermansia muciniphila | Reduces |
| species | Bifidobacterium adolescentis | Reduces |
| species | Bifidobacterium longum | Reduces |
| species | Escherichia coli | Reduces |
| species | Lacticaseibacillus paracasei | Reduces |
| subspecies | Bifidobacterium longum subsp. infantis | Reduces |
| subspecies | Bifidobacterium longum subsp. longum | Reduces |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
| Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
|---|---|---|---|
| Abdominal Aortic Aneurysm | 0.3 | 0.3 | |
| Acne | 0.2 | -0.2 | |
| ADHD | 2.9 | 0.1 | 28 |
| Age-Related Macular Degeneration and Glaucoma | 0.4 | 0 | 0 |
| Allergic Rhinitis (Hay Fever) | 0.4 | 1.1 | -1.75 |
| Allergies | 2.1 | 1.7 | 0.24 |
| Allergy to milk products | 0.6 | 0.4 | 0.5 |
| Alopecia (Hair Loss) | 0.4 | 0.4 | |
| Alzheimer's disease | 2.5 | 2.9 | -0.16 |
| Amyotrophic lateral sclerosis (ALS) Motor Neuron | 2.9 | 1.2 | 1.42 |
| Ankylosing spondylitis | 1.6 | 0.9 | 0.78 |
| Anorexia Nervosa | 0 | 1 | 0 |
| Antiphospholipid syndrome (APS) | 1.3 | 0.3 | 3.33 |
| Asthma | 0.5 | 1.6 | -2.2 |
| Atherosclerosis | 0.7 | 1.8 | -1.57 |
| Atrial fibrillation | 1.6 | 1 | 0.6 |
| Autism | 4.6 | 5.3 | -0.15 |
| Barrett esophagus cancer | 0.7 | 0.7 | |
| benign prostatic hyperplasia | 0.1 | 0.1 | |
| Bipolar Disorder | 0.8 | 0.9 | -0.13 |
| Brain Trauma | 0.3 | 0.4 | -0.33 |
| Carcinoma | 1.9 | 1.3 | 0.46 |
| Celiac Disease | 1.3 | 3 | -1.31 |
| Cerebral Palsy | 1 | 0.7 | 0.43 |
| Chronic Fatigue Syndrome | 2.7 | 2.4 | 0.13 |
| Chronic Kidney Disease | 0.7 | 0.7 | 0 |
| Chronic Lyme | 0.4 | -0.4 | |
| Chronic Obstructive Pulmonary Disease (COPD) | 0.7 | 0.5 | 0.4 |
| Chronic Urticaria (Hives) | 0.9 | 1.1 | -0.22 |
| Coagulation / Micro clot triggering bacteria | 0.5 | 0.5 | 0 |
| Colorectal Cancer | 2.5 | 0.3 | 7.33 |
| Constipation | 0.7 | 0.3 | 1.33 |
| Coronary artery disease | 0.2 | 0.5 | -1.5 |
| COVID-19 | 6.5 | 7.6 | -0.17 |
| Crohn's Disease | 4.2 | 3.3 | 0.27 |
| cystic fibrosis | 0.4 | 0.7 | -0.75 |
| deep vein thrombosis | 0.4 | 0.4 | 0 |
| Depression | 4.9 | 3.4 | 0.44 |
| Dermatomyositis | 0.2 | -0.2 | |
| Eczema | 0.6 | 0.4 | 0.5 |
| Endometriosis | 1.2 | 1.3 | -0.08 |
| Eosinophilic Esophagitis | 0.2 | 0.4 | -1 |
| Epilepsy | 1.6 | 1.7 | -0.06 |
| Fibromyalgia | 0.8 | 0.7 | 0.14 |
| Functional constipation / chronic idiopathic constipation | 3.1 | 1.4 | 1.21 |
| gallstone disease (gsd) | 1 | 0.7 | 0.43 |
| Gastroesophageal reflux disease (Gerd) including Barrett's esophagus | 0.9 | 0.2 | 3.5 |
| Generalized anxiety disorder | 0.8 | 0.8 | 0 |
| Graves' disease | 0.6 | 0.6 | 0 |
| Halitosis | 0.9 | 0.9 | |
| Hashimoto's thyroiditis | 1.4 | 0.7 | 1 |
| Hidradenitis Suppurativa | 0.5 | 0.4 | 0.25 |
| Histamine Issues,Mast Cell Issue, DAO Insufficiency | 2 | 0.2 | 9 |
| hypercholesterolemia (High Cholesterol) | 0.4 | 0.7 | -0.75 |
| hyperglycemia | 0.1 | 1.7 | -16 |
| Hyperlipidemia (High Blood Fats) | 0.7 | 0.1 | 6 |
| hypersomnia | 0.4 | -0.4 | |
| hypertension (High Blood Pressure | 1.2 | 3.1 | -1.58 |
| Hypothyroidism | 0.5 | -0.5 | |
| Hypoxia | 0.6 | 0.6 | |
| IgA nephropathy (IgAN) | 2.3 | -2.3 | |
| Inflammatory Bowel Disease | 1.5 | 4 | -1.67 |
| Insomnia | 0.3 | 0.8 | -1.67 |
| Intelligence | 0.1 | 0.1 | 0 |
| Intracranial aneurysms | 0.5 | 0.1 | 4 |
| Irritable Bowel Syndrome | 3.3 | 3 | 0.1 |
| Liver Cirrhosis | 2.9 | 2.1 | 0.38 |
| Long COVID | 4 | 5.1 | -0.27 |
| Low bone mineral density | 0.5 | -0.5 | |
| Lung Cancer | 0.5 | 1.1 | -1.2 |
| ME/CFS with IBS | 0.3 | 1 | -2.33 |
| ME/CFS without IBS | 0.5 | 1 | -1 |
| Menopause | 1.6 | 1.6 | |
| Metabolic Syndrome | 3.7 | 4.8 | -0.3 |
| Mood Disorders | 7 | 3.6 | 0.94 |
| multiple chemical sensitivity [MCS] | 0.8 | 0.1 | 7 |
| Multiple Sclerosis | 3 | 1.5 | 1 |
| Multiple system atrophy (MSA) | 1.5 | 0.5 | 2 |
| Neuropathy (all types) | 0.5 | 0.1 | 4 |
| neuropsychiatric disorders (PANDAS, PANS) | 0.7 | 0.7 | |
| Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | 0.6 | 3.2 | -4.33 |
| NonCeliac Gluten Sensitivity | 0.2 | -0.2 | |
| Obesity | 4.1 | 2.7 | 0.52 |
| obsessive-compulsive disorder | 3.3 | 2.1 | 0.57 |
| Osteoarthritis | 0.5 | 0.1 | 4 |
| Osteoporosis | 1.1 | 1 | 0.1 |
| pancreatic cancer | 0.4 | 0.4 | |
| Parkinson's Disease | 2.2 | 2.3 | -0.05 |
| Polycystic ovary syndrome | 0.6 | 1.5 | -1.5 |
| Postural orthostatic tachycardia syndrome | 0.2 | -0.2 | |
| Premenstrual dysphoric disorder | 0.4 | 0 | 0 |
| primary biliary cholangitis | 0.2 | 0.2 | 0 |
| Psoriasis | 2.3 | 1.3 | 0.77 |
| rheumatoid arthritis (RA),Spondyloarthritis (SpA) | 3.2 | 2.2 | 0.45 |
| Rosacea | 0.5 | 0.2 | 1.5 |
| Schizophrenia | 4.5 | 0.7 | 5.43 |
| scoliosis | 1 | -1 | |
| Sjögren syndrome | 2.1 | 1.4 | 0.5 |
| Sleep Apnea | 0.7 | 0.7 | 0 |
| Small Intestinal Bacterial Overgrowth (SIBO) | 0.5 | 0.4 | 0.25 |
| Stress / posttraumatic stress disorder | 1.8 | 1.8 | 0 |
| Systemic Lupus Erythematosus | 2.1 | 1.4 | 0.5 |
| Tic Disorder | 0.5 | 0.6 | -0.2 |
| Tourette syndrome | 0.4 | 0.2 | 1 |
| Type 1 Diabetes | 2.2 | 1.1 | 1 |
| Type 2 Diabetes | 3.7 | 3.7 | 0 |
| Ulcerative colitis | 1.2 | 3.4 | -1.83 |
| Unhealthy Ageing | 2.7 | 1.2 | 1.25 |
This is an Academic site. It generates theoretical models of what may benefit a specific microbiome results.
Explanations/Info/Descriptions are influenced by Large Language Models and may not be accurate and include some hallucinations. Please report any to us for correction.
Copyright 2016-2024 Lassesen Consulting, LLC [2007], DBA, Microbiome Prescription. All rights served.
Permission to data scrap or reverse engineer is explicitly denied to all users. U.S. Code Title 18 PART I CHAPTER 47 § 1030, CETS No.185, CFAA
Use of data on this site is prohibited except under written license. There is no charge for individual personal use. Use for any commercial applications or research requires a written license.
Caveat emptor: Analysis and suggestions are based on modelling (and thus infererence) based on studies. The data sources are usually given for those that wish to consider alternative inferences. theories and models.
Inventions/Methodologies on this site are Patent Pending.
Microbiome Prescription do not make any representations that data or analyses available on this site is suitable for human diagnostic purposes, for informing treatment decisions, or for any other purposes and accept no responsibility or liability whatsoever for such use.
This site is not Health Insurance Portability and Accountability Act of 1996 (HIPAA) compliant.