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Digestive Health: Probiotics containing Lactobacillus paracasei, Lactobacillus acidophilus, and Bifidobacterium animalis may contribute to digestive health by promoting a balanced gut microbiota, aiding in the breakdown of food, and producing beneficial metabolites such as short-chain fatty acids. They may help alleviate symptoms of digestive disorders such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and diarrhea by modulating gut inflammation, enhancing gut barrier function, and promoting regular bowel movements.
Immune Function: The combination of Lactobacillus paracasei, Lactobacillus acidophilus, and Bifidobacterium animalis may have immunomodulatory effects, meaning they can help regulate the immune system. They may enhance immune function by stimulating the production of certain immune cells and cytokines, promoting a balanced immune response, and reducing the risk of infections and inflammatory conditions.
Women's Health: Probiotics containing these strains may benefit women's health by promoting vaginal health and reducing the risk of urogenital infections such as bacterial vaginosis and urinary tract infections (UTIs). They can help restore the balance of vaginal microbiota and create an acidic environment that inhibits the growth of harmful bacteria.
Dental Health: The combination of Lactobacillus paracasei, Lactobacillus acidophilus, and Bifidobacterium animalis may contribute to oral health by reducing the growth of harmful bacteria in the mouth and preventing dental caries (cavities) and gum disease. They can help maintain a healthy balance of oral microbiota and promote oral hygiene.
Skin Health: Some studies have suggested that probiotics containing Lactobacillus paracasei, Lactobacillus acidophilus, and Bifidobacterium animalis may have beneficial effects on skin health, including reducing the severity of acne, improving skin hydration and elasticity, and promoting wound healing. These effects may be attributed to the anti-inflammatory and immunomodulatory properties of the probiotic combination.
Mental Health: There is emerging evidence to suggest that probiotics containing Lactobacillus paracasei, Lactobacillus acidophilus, and Bifidobacterium animalis may have beneficial effects on mental health and mood regulation. Some research indicates that supplementation with this probiotic combination may help reduce symptoms of anxiety and depression, potentially by modulating neurotransmitter levels, reducing inflammation, and promoting gut-brain communication via the gut microbiota-brain axis.
Rank | Probiotic | Impact |
---|---|---|
species | Clostridium beijerinckii | Reduces |
species | Clostridium butyricum | Reduces |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
---|---|---|---|
Acne | 0.3 | 0.4 | -0.33 |
ADHD | 0.3 | 0.3 | 0 |
Allergic Rhinitis (Hay Fever) | 0.5 | 0.4 | 0.25 |
Allergies | 0.5 | 0.5 | 0 |
Allergy to milk products | 0.5 | 0.5 | |
Alzheimer's disease | 1.2 | -1.2 | |
Anorexia Nervosa | 0.3 | 0.8 | -1.67 |
Asthma | 1 | 0.2 | 4 |
Atherosclerosis | 0.5 | -0.5 | |
Atrial fibrillation | 0.3 | -0.3 | |
Autism | 1.4 | 0.7 | 1 |
Bipolar Disorder | 0.2 | 0.2 | |
Brain Trauma | 0.3 | 0.3 | |
Breast Cancer | 0.2 | 0.2 | |
Cerebral Palsy | 0.5 | 0.5 | |
Chronic Fatigue Syndrome | 1 | 0.4 | 1.5 |
Chronic Kidney Disease | 0.2 | -0.2 | |
Chronic Urticaria (Hives) | 0.5 | 0.5 | |
Colorectal Cancer | 0.2 | -0.2 | |
COVID-19 | 0.5 | 0.8 | -0.6 |
Crohn's Disease | 0.7 | 0.4 | 0.75 |
Depression | 0.9 | 1.3 | -0.44 |
Eczema | 0.5 | 1 | -1 |
Endometriosis | 0.3 | -0.3 | |
Eosinophilic Esophagitis | 0.3 | -0.3 | |
Epilepsy | 0.3 | 0.3 | |
Fibromyalgia | 0.8 | 0.5 | 0.6 |
Functional constipation / chronic idiopathic constipation | 0.5 | 0.5 | 0 |
gallstone disease (gsd) | 0.5 | 0.5 | |
Generalized anxiety disorder | 0.5 | -0.5 | |
giant cell arteritis | 0.5 | 0.5 | 0 |
Graves' disease | 0.3 | -0.3 | |
Halitosis | 0.3 | 0.3 | |
Hashimoto's thyroiditis | 0.2 | 0.2 | |
hypercholesterolemia (High Cholesterol) | 0.8 | 0.8 | |
hypertension (High Blood Pressure | 0.2 | 0.2 | 0 |
Hypothyroidism | 0.2 | 0.2 | 0 |
IgA nephropathy (IgAN) | 0.5 | -0.5 | |
Inflammatory Bowel Disease | 0.9 | -0.9 | |
Intelligence | 0.5 | 0.5 | |
Intracranial aneurysms | 0.3 | 0.3 | |
Irritable Bowel Syndrome | 0.8 | 0.8 | |
Liver Cirrhosis | 0.5 | 0.7 | -0.4 |
Long COVID | 0.8 | 0.6 | 0.33 |
Lung Cancer | 0.2 | 0.3 | -0.5 |
ME/CFS with IBS | 0.5 | 0.5 | |
ME/CFS without IBS | 1 | 1 | |
Menopause | 0.2 | -0.2 | |
Metabolic Syndrome | 1.1 | 1.3 | -0.18 |
Mood Disorders | 1.4 | 1.3 | 0.08 |
Multiple Sclerosis | 0.8 | -0.8 | |
myasthenia gravis | 0.5 | -0.5 | |
Neuropathy (all types) | 0.3 | 0.3 | |
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | 0.5 | 0.5 | |
Obesity | 0.9 | 0.6 | 0.5 |
Osteoarthritis | 0.5 | 0.5 | |
Osteoporosis | 0.5 | 0.5 | |
Parkinson's Disease | 0.6 | 0.6 | 0 |
Polycystic ovary syndrome | 1 | 0.5 | 1 |
Postural orthostatic tachycardia syndrome | 0.5 | 0.5 | |
Premenstrual dysphoric disorder | 0.2 | -0.2 | |
Psoriasis | 0.5 | 0.5 | |
rheumatoid arthritis (RA),Spondyloarthritis (SpA) | 1.1 | 1 | 0.1 |
Rosacea | 0.2 | 0.5 | -1.5 |
Schizophrenia | 1.1 | 0.5 | 1.2 |
Stress / posttraumatic stress disorder | 0.5 | 0.5 | |
Systemic Lupus Erythematosus | 0.7 | 0.3 | 1.33 |
Type 1 Diabetes | 0.5 | -0.5 | |
Type 2 Diabetes | 0.4 | 1.3 | -2.25 |
Ulcerative colitis | 0.5 | 1.1 | -1.2 |
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