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Bone Health: Calcium is a primary component of bone tissue, and adequate calcium intake is essential for building and maintaining strong and healthy bones. Calcium helps to form the structural matrix of bones and teeth, contributing to bone density and strength. Insufficient calcium intake can lead to a decrease in bone mineral density and increase the risk of osteoporosis, a condition characterized by fragile and porous bones that are more prone to fractures.
Prevention of Osteoporosis: Adequate calcium intake, along with other bone-supportive nutrients like vitamin D and magnesium, is essential for reducing the risk of osteoporosis and age-related bone loss. Calcium supplementation or consumption of calcium-rich foods can help maintain bone density and minimize the risk of fractures, particularly in postmenopausal women and older adults who are at greater risk of osteoporosis.
Muscle Function and Contraction: Calcium ions play a critical role in muscle contraction and relaxation. During muscle contraction, calcium is released from storage sites within muscle cells, triggering a series of biochemical reactions that result in muscle fiber contraction. Adequate calcium levels are necessary for normal muscle function, including voluntary movements, cardiac muscle contraction (heart function), and smooth muscle activity in organs like the intestines and blood vessels.
Nerve Transmission: Calcium ions are involved in nerve impulse transmission, facilitating the release of neurotransmitters at synapses (junctions between nerve cells). Calcium influx into nerve cells initiates the release of neurotransmitters such as acetylcholine, which transmit electrical signals between neurons and regulate various physiological processes, including muscle contraction, sensory perception, and cognitive function.
Blood Clotting: Calcium is essential for blood clotting (coagulation), a complex process that prevents excessive bleeding following injury. When blood vessels are damaged, platelets adhere to the site of injury and release chemical signals that activate the clotting cascade. Calcium ions serve as cofactors for several clotting factors and enzymes involved in the coagulation process, ultimately leading to the formation of a stable blood clot that seals the wound and stops bleeding.
Regulation of Hormonal Secretion: Calcium plays a role in the regulation of hormone secretion and signaling pathways in various glands and tissues. Calcium ions are involved in the release of hormones such as insulin from pancreatic beta cells, parathyroid hormone (PTH) from the parathyroid glands, and calcitonin from the thyroid gland. These hormones help regulate calcium balance in the body by influencing calcium absorption, excretion, and bone turnover.
Cardiovascular Health: Calcium is involved in maintaining normal heart function and regulating cardiac muscle contraction. Calcium ions facilitate the generation and propagation of electrical impulses in the heart, contributing to the rhythmic beating of the heart (cardiac cycle). Adequate calcium levels are necessary for normal heart rate, rhythm, and blood pressure regulation.
| Rank | Probiotic | Impact |
|---|---|---|
| species | Oxalobacter formigenes | Increases |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
| Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
|---|---|---|---|
| Abdominal Aortic Aneurysm | 0.6 | -0.6 | |
| Allergic Rhinitis (Hay Fever) | 0.6 | 0.6 | |
| Brain Trauma | 0.3 | 0.3 | |
| Colorectal Cancer | 0.2 | -0.2 | |
| COVID-19 | 0.2 | -0.2 | |
| Depression | 0.1 | -0.1 | |
| Hidradenitis Suppurativa | 0.1 | -0.1 | |
| hypercholesterolemia (High Cholesterol) | 0.2 | 0.2 | |
| Intelligence | 0.6 | 0.6 | |
| Irritable Bowel Syndrome | 0.6 | 0.6 | |
| Liver Cirrhosis | 0.6 | -0.6 | |
| Long COVID | 0.2 | -0.2 | |
| Metabolic Syndrome | 0.2 | 0.6 | -2 |
| Mood Disorders | 0.1 | -0.1 | |
| obsessive-compulsive disorder | 0.2 | 0.2 | |
| rheumatoid arthritis (RA),Spondyloarthritis (SpA) | 0.6 | -0.6 | |
| Stress / posttraumatic stress disorder | 0.2 | 0.2 | |
| Type 2 Diabetes | 0.6 | -0.6 | |
| Ulcerative colitis | 0.6 | 0.6 | |
| Unhealthy Ageing | 0.6 | 0.6 |
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