We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.
This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.
Symptom | Impact | Predictor of Bacteria Shift |
---|---|---|
Age: 20-30 | Worsen | 2.48 |
We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.
This is according to the microbiome shifts reported in studies. Clinical studies may show different results
Symptom | Impact | Predictor of Bacteria Shift |
---|---|---|
Allergies | Worsen | 2.23 |
Ankylosing spondylitis | Worsen | 3.29 |
Asthma | Worsen | 0 |
Atherosclerosis | Improves | -1.96 |
Autism | Improves | -2.48 |
Celiac Disease | Improves | -2.48 |
Colorectal Cancer | Improves | -1.74 |
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus | Worsen | 2.01 |
High Blood Pressure | Worsen | 0 |
Hyperlipidemia (High Blood Fats) | Improves | -2.01 |
Inflammatory Bowel Disease | Improves | -2.48 |
Liver Cirrhosis | Worsen | 1.7 |
Obesity | Worsen | 0 |
Osteoporosis | Improves | -2.01 |
Psoriasis | Improves | -2.23 |
Rheumatoid arthritis | Improves | -2.48 |
rheumatoid arthritis (RA),Spondyloarthritis (SpA) | Improves | -2.48 |
Small Intestinal Bacterial Overgrowth (SIBO) | Improves | -2.48 |
Stress / posttraumatic stress disorder | Improves | -3.8 |
Type 1 Diabetes | Worsen | 2.48 |
Type 2 Diabetes | Worsen | 0 |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.