lactobacillus fermentum (probiotics) ** full range

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Citizen Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.

Symptom	Impact	Predictor of Bacteria Shift
Age: 20-30	Worsen	2.48
Age: 60-70	Improves	-1.7
Asymptomatic: No Health Issues	Worsen	2.72
Blood Type: A Positive	Worsen	1.86
Blood Type: O Positive	Worsen	1.86
Comorbid: Histamine or Mast Cell issues	Improves	-1.7
Comorbid: Inflammatory bowel disease	Worsen	1.86
Comorbid: Migraine	Worsen	3.16
Comorbid: Multiple Chemical Sensitivity	Improves	-2.9
DePaul University Fatigue Questionnaire : Fatigue	Worsen	3.08
DePaul University Fatigue Questionnaire : Impaired Memory & concentration	Worsen	2.8
DePaul University Fatigue Questionnaire : Unrefreshing Sleep, that is waking up feeling tired	Improves	-2.28
General: Headaches	Improves	-1.62
Immune Manifestations: tender lymph nodes	Improves	-2.9
Joint: Stiffness and swelling	Improves	-1.7
Joint: Tenderness	Worsen	2.8
Neuroendocrine Manifestations: Excessive adrenaline	Improves	-1.68
Neuroendocrine Manifestations: intolerance of extremes of heat and cold	Improves	-2.9
Neuroendocrine Manifestations: Muscle weakness	Improves	-2.9
Neuroendocrine: Alcohol intolerance	Improves	-1.7
Neurological: Slowed speech	Improves	-1.61
Official Diagnosis: Mast Cell Dysfunction	Improves	-1.7
Onset: Gradual	Improves	-2.65
Sleep: Problems staying asleep	Improves	-1.7

Published Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is according to the microbiome shifts reported in studies. Clinical studies may show different results

Symptom	Impact	Predictor of Bacteria Shift
Acne	Improves	-2.72
Allergies	Improves	-1.94
Ankylosing spondylitis	Worsen	4.02
Asthma	Improves	-2.9
Atherosclerosis	Worsen	3.96
Autism	Worsen	1.45
Barrett esophagus cancer	Improves	-3.16
Celiac Disease	Improves	-3.37
Chronic Fatigue Syndrome	Improves	-3.38
Chronic Kidney Disease	Improves	-2.28
Colorectal Cancer	Improves	-1.93
Coronary artery disease	Improves	-1.44
Crohn's Disease	Worsen	2.62
Depression	Worsen	2.64
Epilepsy	Improves	-3.48
Fibromyalgia	Improves	-2.72
Functional constipation / chronic idiopathic constipation	Worsen	2.72
gallstone disease (gsd)	Worsen	2.72
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus	Improves	-1.46
High Blood Pressure	Improves	-2.72
Histamine Issues	Worsen	1.84
Histamine Issues From Ubiome	Improves	-2.96
Hyperlipidemia (High Blood Fats)	Worsen	2.96
IgA nephropathy (IgAN)	Improves	-3.38
Inflammatory Bowel Disease	Worsen	1.46
Irritable Bowel Syndrome	Improves	-3.52
Liver Cirrhosis	Worsen	3.42
ME/CFS with IBS	Worsen	0
ME/CFS without IBS	Worsen	1.7
Metabolic Syndrome	Improves	-2.9
Multiple Sclerosis	Worsen	3.06
Multiple system atrophy (MSA)	Worsen	3.48
Obesity	Improves	-3.03
Osteoporosis	Worsen	3.71
Parkinson's Disease	Worsen	4.55
Psoriasis	Worsen	2.3
Rheumatoid arthritis	Improves	-3.26
rheumatoid arthritis (RA),Spondyloarthritis (SpA)	Worsen	1.45
Rosacea	Improves	-2.72
Schizophrenia	Worsen	3.38
Small Intestinal Bacterial Overgrowth (SIBO)	Improves	-2.48
Stress / posttraumatic stress disorder	Improves	-3.31
Systemic Lupus Erythematosus	Improves	-2.09
Type 1 Diabetes	Improves	-1.45
Type 2 Diabetes	Improves	-3.59
Ulcerative colitis	Improves	-1.81

Bacteria Impacted

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.