We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.
This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.
Symptom | Impact | Predictor of Bacteria Shift |
---|---|---|
Asymptomatic: No Health Issues | Worsen | 1.6 |
Immune Manifestations: Diarrhea | Improves | -1.93 |
Immune Manifestations: Inflammation (General) | Improves | -3.24 |
Immune Manifestations: tender lymph nodes | Worsen | 2.9 |
Neuroendocrine Manifestations: Excessive adrenaline | Improves | -2.9 |
We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.
This is according to the microbiome shifts reported in studies. Clinical studies may show different results
Symptom | Impact | Predictor of Bacteria Shift |
---|---|---|
Cerebral Palsy | Improves | -2.9 |
Allergies | Worsen | 2.9 |
Alzheimer's disease | Worsen | 3.6 |
Ankylosing spondylitis | Worsen | 3.63 |
Asthma | Improves | -2.9 |
Atherosclerosis | Improves | -0.95 |
Autism | Improves | -3.93 |
Chronic Fatigue Syndrome | Improves | -3.99 |
Chronic urticaria (Hives) | Improves | -2.9 |
Colorectal Cancer | Improves | -3.72 |
Crohn's Disease | Improves | -2.9 |
Depression | Improves | -2.9 |
Fibromyalgia | Worsen | 2.9 |
gallstone disease (gsd) | Improves | -2.9 |
High Blood Pressure | Improves | -1.16 |
IgA nephropathy (IgAN) | Worsen | 2.9 |
Inflammatory Bowel Disease | Worsen | 3.56 |
Liver Cirrhosis | Worsen | 3.4 |
ME/CFS with IBS | Improves | -2.9 |
ME/CFS without IBS | Improves | -3.99 |
Multiple Sclerosis | Worsen | 3.56 |
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | Improves | -2.9 |
Obesity | Improves | -3.05 |
Osteoporosis | Improves | -2.9 |
Psoriasis | Improves | -2.9 |
Rheumatoid arthritis | Worsen | 3.48 |
Rosacea | Worsen | 2.51 |
Schizophrenia | Worsen | 2.9 |
Sclerosis | Worsen | 2.9 |
Stress / posttraumatic stress disorder | Improves | -2.9 |
Systemic Lupus Erythematosus | Improves | -3.11 |
Type 2 Diabetes | Worsen | 2.86 |
Ulcerative colitis | Worsen | 2.9 |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.