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Citizen Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.

SymptomImpactPredictor of Bacteria Shift
Age: 60-70Worsen2.39
Asymptomatic: No Health IssuesWorsen1.9
Autism: Official DiagnosisWorsen1.76
Autonomic Manifestations: cardiac arrhythmiasWorsen1.15
Autonomic Manifestations: Cortisol disorders or irregularity Improves-1.7
Autonomic Manifestations: irritable bowel syndromeWorsen2.39
Autonomic Manifestations: Orthostatic intoleranceWorsen0.19
Autonomic: Inability to tolerate an upright positionWorsen3.05
Autonomic: Irregular heartbeatsWorsen3.05
Autonomic: Shortness of breathWorsen1.67
Blood Type: A PositiveWorsen1.76
Blood Type: O PositiveImproves-1.51
Comorbid-Mouth: Bruxism - Jaw cleanching / Teeth grindingWorsen2.39
Comorbid-Mouth: Dry MouthImproves-3.05
Comorbid-Mouth: Mouth SoresImproves-1.84
Comorbid-Mouth: TMJ / Dysfunction of the temporomandibular joint syndromeWorsen3.29
Comorbid: Constipation and Explosions (not diarrohea)Worsen3.58
Comorbid: FibromyalgiaWorsen2.71
Comorbid: High AnxietyWorsen2.87
Comorbid: Histamine or Mast Cell issuesWorsen2.39
Comorbid: HypothyroidismWorsen3.05
Comorbid: Inflammatory bowel disease Worsen3.21
Comorbid: Multiple Chemical SensitivityImproves-3.55
Comorbid: Snoring (NOT Sleep ApneaWorsen3.44
DePaul University Fatigue Questionnaire : Anxiety/tensionWorsen0.54
DePaul University Fatigue Questionnaire : FatigueWorsen3.25
DePaul University Fatigue Questionnaire : Impaired Memory & concentrationWorsen3.05
DePaul University Fatigue Questionnaire : Unrefreshing Sleep, that is waking up feeling tired Worsen1.76
General: DepressionImproves-1.71
General: FatigueImproves-2.9
General: HeadachesWorsen2.39
Immune Manifestations: Abdominal PainWorsen3.05
Immune Manifestations: Alcohol IntolerantWorsen2.39
Immune Manifestations: BloatingWorsen2.39
Immune Manifestations: ConstipationWorsen2.39
Immune Manifestations: DiarrheaImproves-1.67
Immune Manifestations: general malaiseWorsen2.39
Immune Manifestations: Hair lossWorsen1.9
Immune Manifestations: Mucus in the stoolWorsen2.83
Infection: Human Herpesvirus 6 (HHV6)Worsen3.29
Infection: MycoplasmaWorsen3.05
Infection: Parasite - OtherWorsen3.05
Joint: Stiffness and swellingWorsen2.39
Joint: TendernessWorsen3.24
Neurocognitive: Absent-mindedness or forgetfulnessWorsen2.39
Neurocognitive: Brain FogWorsen2.39
Neurocognitive: Can only focus on one thing at a timeWorsen2.39
Neurocognitive: Slowness of thoughtWorsen2.39
Neuroendocrine Manifestations: intolerance of extremes of heat and coldImproves-3.43
Neuroendocrine Manifestations: Muscle weakness Improves-3.92
Neuroendocrine Manifestations: Paraesthesia (tingling burning of skin)Worsen3.05
Neuroendocrine Manifestations: subnormal body temperatureWorsen3.44
Neuroendocrine Manifestations: worsening of symptoms with stress.Worsen2.39
Neuroendocrine: Alcohol intoleranceWorsen3.44
Neuroendocrine: Cold limbs (e.g. arms, legs hands)Improves-1.71
Neuroendocrine: Feeling like you have a low temperatureWorsen3.11
Neuroendocrine: Lost or gained weight without tryingImproves-3.35
Neurological-Audio: hypersensitivity to noiseWorsen3.44
Neurological-Audio: Tinnitus (ringing in ear)Improves-2.96
Neurological-Sleep: Chaotic diurnal sleep rhythms (Erratic Sleep)Worsen0.34
Neurological-Sleep: InsomniaWorsen2.64
Neurological-Sleep: Sleep ApneaImproves-1.97
Neurological-Vision: inability to focus eye/visionWorsen3.44
Neurological: Difficulty processing information (Understanding)Worsen1.67
Neurological: Difficulty readingWorsen2.39
Neurological: fasciculations Improves-2.84
Neurological: Impairment of concentrationWorsen2.39
Neurological: Joint hypermobilityWorsen3.05
Neurological: Seasonal Affective Disorder (SAD)Improves-0.86
Neurological: Short-term memory issuesImproves-1.56
Neurological: Word-finding problemsWorsen1.79
Official Diagnosis: Allergic Rhinitis (Hay Fever)Worsen2.87
Official Diagnosis: Irritable Bowel SyndromeWorsen2.39
Official Diagnosis: Mast Cell DysfunctionWorsen3.25
Onset: 2010-2020Worsen2.39
Onset: GradualImproves-1.67
Other: Sensitivity to moldImproves-2.3
Pain: Chest painImproves-2.96
Pain: Sensitivity to painWorsen3.05
Sleep: Daytime drowsinessWorsen2.39
Sleep: Problems staying asleepWorsen1.72
Sleep: Waking up early in the morning (e.g. 3 AM)Worsen2.39

Published Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is according to the microbiome shifts reported in studies. Clinical studies may show different results

SymptomImpactPredictor of Bacteria Shift
AcneWorsen3.13
ADHDWorsen3.55
Allergic Rhinitis (Hay Fever)Worsen2.56
AllergiesImproves-2.51
Alzheimer's diseaseWorsen4.44
Amyotrophic lateral sclerosis (ALS) Motor NeuronImproves-3.42
Ankylosing spondylitisWorsen3.05
AsthmaWorsen1.09
AtherosclerosisWorsen4.47
AutismImproves-4.18
Barrett esophagus cancerWorsen3.01
Bipolar DisorderWorsen2.43
Brain TraumaWorsen2.86
CarcinomaWorsen0
Celiac DiseaseImproves-4.06
Cerebral PalsyImproves-1.38
Chronic Fatigue SyndromeWorsen2.81
Chronic Kidney DiseaseWorsen3.34
Chronic Urticaria (Hives)Improves-0.92
Colorectal CancerWorsen1.54
Coronary artery disease Improves-1.09
COVID-19Worsen1.34
Crohn's DiseaseWorsen4.75
cystic fibrosisImproves-3.57
DepressionImproves-2.58
EpilepsyImproves-2.7
FibromyalgiaWorsen3.12
Functional constipation / chronic idiopathic constipationImproves-3.94
gallstone disease (gsd)Worsen3.05
Gastroesophageal reflux disease (Gerd) including Barrett's esophagusWorsen3.67
Generalized anxiety disorderWorsen3.96
GoutImproves-2.96
Graves' diseaseWorsen1.1
Hashimoto's thyroiditisWorsen3.3
High Blood PressureImproves-4.06
Histamine IssuesImproves-2.43
hypercholesterolemia (High Cholesterol)Improves-2.87
Hyperlipidemia (High Blood Fats)Worsen4.23
IgA nephropathy (IgAN)Improves-2.64
Inflammatory Bowel DiseaseImproves-2.46
InsomniaWorsen3.05
Irritable Bowel SyndromeImproves-2.13
Liver CirrhosisWorsen4.62
ME/CFS with IBSImproves-1.84
ME/CFS without IBSWorsen1.29
Metabolic SyndromeWorsen1.09
Multiple SclerosisWorsen5.19
Multiple system atrophy (MSA)Worsen2.68
neuropsychiatric disorders (PANDAS, PANS)Improves-2.97
Nonalcoholic Fatty Liver Disease (nafld) NonalcoholicWorsen3.97
ObesityImproves-4.43
OsteoarthritisWorsen2.64
OsteoporosisImproves-2.73
Parkinson's DiseaseWorsen5.37
PsoriasisWorsen3.79
rheumatoid arthritis (RA),Spondyloarthritis (SpA)Worsen5.12
RosaceaImproves-3.01
SchizophreniaWorsen2.77
Sjögren syndromeImproves-3.01
Small Intestinal Bacterial Overgrowth (SIBO)Improves-2.21
Stress / posttraumatic stress disorderWorsen2.87
Systemic Lupus ErythematosusWorsen3.54
Type 1 DiabetesImproves-2.68
Type 2 DiabetesImproves-4.3
Ulcerative colitisWorsen3.57

Bacteria Impacted

Suggest a missed study:

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

📓 - direct citation | 👪 - Impacts Parent Taxa | 👶 - Impacts Child Taxa | 🧙 - Inferred
Taxonomy Rank Effect Citations
Alphaproteobacteria class Increases 📓 Source Study
Betaproteobacteria class Increases 📓 Source Study
Gammaproteobacteria class Increases 📓 Source Study
Zetaproteobacteria class Increases 📓 Source Study
Bacteroidaceae family Decreases 📓 Source Study
Enterobacteriaceae family Decreases 📓 Source Study
Porphyromonadaceae family Decreases 📓 Source Study
Prevotellaceae family Decreases 📓 Source Study
Rikenellaceae family Decreases 📓 Source Study
Lachnospiraceae family Increases 📓 Source Study
Verrucomicrobiaceae family Increases 📓 Source Study
Pseudomonas genus Decreases 📓 Source Study
Acetobacteroides genus Decreases 👪 Source Study
Alloprevotella genus Decreases 👪 Source Study
Anaerocella genus Decreases 👪 Source Study
Anaerorhabdus genus Decreases 👪 Source Study
Caballeronia genus Decreases 👪 Source Study
Chitinimonas genus Decreases 👪 Source Study
Cupriavidus genus Decreases 👪 Source Study
Falsiporphyromonas genus Decreases 👪 Source Study
Fermentimonas genus Decreases 👪 Source Study
Gabonibacter genus Decreases 👪 Source Study
Lautropia genus Decreases 👪 Source Study
Limnobacter genus Decreases 👪 Source Study
Massiliprevotella genus Decreases 👪 Source Study
Mediterranea genus Decreases 👪 Source Study
Metaprevotella genus Decreases 👪 Source Study
Microbacter genus Decreases 👪 Source Study
Mucinivorans genus Decreases 👪 Source Study
Pandoraea genus Decreases 👪 Source Study
Paraburkholderia genus Decreases 👪 Source Study
Paraprevotella genus Decreases 👪 Source Study
Paucimonas genus Decreases 👪 Source Study
Petrimonas genus Decreases 👪 Source Study
Polynucleibacter genus Decreases 👪 Source Study
Prevotellamassilia genus Decreases 👪 Source Study
Pseudomonas chlororaphis group genus Decreases 👪 Source Study
Ralstonia genus Decreases 👪 Source Study
Rikenella genus Decreases 👪 Source Study
Sanguibacteroides genus Decreases 👪 Source Study
Acetatifactor genus Increases 👪 Source Study
Acetitomaculum genus Increases 👪 Source Study
Agathobacter genus Increases 👪 Source Study
Anaerobium genus Increases 👪 Source Study
Anaerobutyricum genus Increases 👪 Source Study
Anaerocolumna genus Increases 👪 Source Study
Anaerosporobacter genus Increases 👪 Source Study
Anaerotaenia genus Increases 👪 Source Study
Anaerotignum genus Increases 👪 Source Study
Brevifollis genus Increases 👪 Source Study
Catonella genus Increases 👪 Source Study
Cellulosilyticum genus Increases 👪 Source Study
Eisenbergiella genus Increases 👪 Source Study
Faecalicatena genus Increases 👪 Source Study
Fusicatenibacter genus Increases 👪 Source Study
Haloferula genus Increases 👪 Source Study
Herbinix genus Increases 👪 Source Study
Hespellia genus Increases 👪 Source Study
Johnsonella genus Increases 👪 Source Study
Lachnoanaerobaculum genus Increases 👪 Source Study
Lachnobacterium genus Increases 👪 Source Study
Lachnotalea genus Increases 👪 Source Study
Luteolibacter genus Increases 👪 Source Study
Merdimonas genus Increases 👪 Source Study
Mobilitalea genus Increases 👪 Source Study
Moryella genus Increases 👪 Source Study
Murimonas genus Increases 👪 Source Study
Oribacterium genus Increases 👪 Source Study
Parasporobacterium genus Increases 👪 Source Study
Persicirhabdus genus Increases 👪 Source Study
Prosthecobacter genus Increases 👪 Source Study
Robinsoniella genus Increases 👪 Source Study
Roseimicrobium genus Increases 👪 Source Study
Sellimonas genus Increases 👪 Source Study
Shuttleworthia genus Increases 👪 Source Study
Sporobacterium genus Increases 👪 Source Study
Stomatobaculum genus Increases 👪 Source Study
Syntrophococcus genus Increases 👪 Source Study
Tyzzerella genus Increases 👪 Source Study
Verrucomicrobium genus Increases 👪 Source Study
Akkermansia genus Increases 📓 Source Study
Blautia genus Increases 📓 Source Study
Bacteroidales order Decreases 📓 Source Study
Proteobacteria phylum Increases 📓 Source Study
Pseudomonas aeruginosa species Decreases 📓 Source Study
Pseudomonas aeruginosa group species Decreases 📓 Source Study
Achromobacter georgiopolitanum species Decreases 👪 Source Study
DSM 6978 species Decreases 👪 Source Study
fluorescent pseudomonads species Decreases 👪 Source Study
KCTC 32541 species Decreases 👪 Source Study
Pseudomonas alcaligenes species Decreases 👪 Source Study
Pseudomonas arsenicoxydans species Decreases 👪 Source Study
Pseudomonas brassicacearum species Decreases 👪 Source Study
Pseudomonas citronellolis species Decreases 👪 Source Study
Pseudomonas denitrificans ATCC 13867 species Decreases 👪 Source Study
Pseudomonas entomophila species Decreases 👪 Source Study
Pseudomonas extremaustralis species Decreases 👪 Source Study
Pseudomonas frederiksbergensis species Decreases 👪 Source Study
Pseudomonas gingeri species Decreases 👪 Source Study
Pseudomonas graminis species Decreases 👪 Source Study
Pseudomonas granadensis species Decreases 👪 Source Study
Pseudomonas guangdongensis species Decreases 👪 Source Study
Pseudomonas koreensis species Decreases 👪 Source Study
Pseudomonas litoralis species Decreases 👪 Source Study
Pseudomonas mendocina species Decreases 👪 Source Study
Pseudomonas moraviensis species Decreases 👪 Source Study
Pseudomonas oryzae species Decreases 👪 Source Study
Pseudomonas parafulva species Decreases 👪 Source Study
Pseudomonas pohangensis species Decreases 👪 Source Study
Pseudomonas prosekii species Decreases 👪 Source Study
Pseudomonas psychrotolerans species Decreases 👪 Source Study
Pseudomonas putida group species Decreases 👪 Source Study
Pseudomonas reinekei species Decreases 👪 Source Study
Pseudomonas resinovorans species Decreases 👪 Source Study
Pseudomonas sabulinigri species Decreases 👪 Source Study
Pseudomonas salegens species Decreases 👪 Source Study
Pseudomonas saponiphila species Decreases 👪 Source Study
Pseudomonas saudiphocaensis species Decreases 👪 Source Study
Pseudomonas sihuiensis species Decreases 👪 Source Study
Pseudomonas soli species Decreases 👪 Source Study
Pseudomonas sp. 02C 26 species Decreases 👪 Source Study
Pseudomonas sp. 31-12 species Decreases 👪 Source Study
Pseudomonas sp. 7SR1 species Decreases 👪 Source Study
Pseudomonas sp. a101-18-2 species Decreases 👪 Source Study
Pseudomonas sp. a111-5 species Decreases 👪 Source Study
Pseudomonas sp. ACM7 species Decreases 👪 Source Study
Pseudomonas sp. CC6-YY-74 species Decreases 👪 Source Study
Pseudomonas sp. CMR12a species Decreases 👪 Source Study
Pseudomonas sp. CMR5c species Decreases 👪 Source Study
Pseudomonas sp. DQ-01 species Decreases 👪 Source Study
Pseudomonas sp. DTU12.3 species Decreases 👪 Source Study
Pseudomonas sp. DY-1 species Decreases 👪 Source Study
Pseudomonas sp. G1116 species Decreases 👪 Source Study
Pseudomonas sp. GmFRB023 species Decreases 👪 Source Study
Pseudomonas sp. KB23 species Decreases 👪 Source Study
Pseudomonas sp. KVS86 species Decreases 👪 Source Study
Pseudomonas sp. LH1G9 species Decreases 👪 Source Study
Pseudomonas sp. LPH1 species Decreases 👪 Source Study
Pseudomonas sp. LTJR-52 species Decreases 👪 Source Study
Pseudomonas sp. MFY143 species Decreases 👪 Source Study
Pseudomonas sp. MRSN12121 species Decreases 👪 Source Study
Pseudomonas sp. MT-1 species Decreases 👪 Source Study
Pseudomonas sp. NS1(2017) species Decreases 👪 Source Study
Pseudomonas sp. PcFRB072 species Decreases 👪 Source Study
Pseudomonas sp. PcFRB119 species Decreases 👪 Source Study
Pseudomonas sp. PONIH3 species Decreases 👪 Source Study
Pseudomonas sp. ps4-2 species Decreases 👪 Source Study
Pseudomonas sp. QZS01 species Decreases 👪 Source Study
Pseudomonas sp. R4-34-07 species Decreases 👪 Source Study
Pseudomonas sp. R5-89-07 species Decreases 👪 Source Study
Pseudomonas sp. RU47 species Decreases 👪 Source Study
Pseudomonas sp. S-6-2 species Decreases 👪 Source Study
Pseudomonas sp. StFLB209 species Decreases 👪 Source Study
Pseudomonas sp. SWI36 species Decreases 👪 Source Study
Pseudomonas sp. TCU-HL1 species Decreases 👪 Source Study
Pseudomonas sp. TMW 2.1634 species Decreases 👪 Source Study
Pseudomonas sp. URMO17WK12:I11 species Decreases 👪 Source Study
Pseudomonas sp. WCS374 species Decreases 👪 Source Study
Pseudomonas straminea species Decreases 👪 Source Study
Pseudomonas stutzeri group species Decreases 👪 Source Study
Pseudomonas syringae group species Decreases 👪 Source Study
Pseudomonas umsongensis species Decreases 👪 Source Study
Pseudomonas versuta species Decreases 👪 Source Study
Pseudomonas xinjiangensis species Decreases 👪 Source Study
Pseudomonas yamanorum species Decreases 👪 Source Study
Akkermansia glycaniphila species Increases 👪 Source Study
Akkermansia sp. species Increases 👪 Source Study
Blautia faecis species Increases 👪 Source Study
Blautia glucerasea species Increases 👪 Source Study
Blautia hansenii species Increases 👪 Source Study
Blautia hydrogenotrophica species Increases 👪 Source Study
Blautia luti species Increases 👪 Source Study
Blautia massiliensis species Increases 👪 Source Study
Blautia obeum species Increases 👪 Source Study
Blautia producta species Increases 👪 Source Study
Blautia schinkii species Increases 👪 Source Study
Blautia sp. species Increases 👪 Source Study
Blautia sp. KCTC 15426 species Increases 👪 Source Study
Blautia sp. MC_32 species Increases 👪 Source Study
Blautia sp. Ser5 species Increases 👪 Source Study
Blautia sp. Ser8 species Increases 👪 Source Study
Blautia sp. YHC-4 species Increases 👪 Source Study
Blautia stercoris species Increases 👪 Source Study
Blautia wexlerae species Increases 👪 Source Study
[Ruminococcus] gnavus species Increases 📓 Source Study
Akkermansia muciniphila species Increases 📓 Source Study
delta/epsilon subdivisions subphylum Increases 📓 Source Study

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