bacillus subtilis natto (probiotics) ** full range

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Citizen Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.

Symptom	Impact	Predictor of Bacteria Shift
Autism: Official Diagnosis	Improves	-2.17
Comorbid: Constipation and Explosions (not diarrohea)	Worsen	1.74
Comorbid: Fibromyalgia	Worsen	2.96
Comorbid: Histamine or Mast Cell issues	Worsen	1.74
Condition: ME/CFS with IBS	Worsen	2.8
DePaul University Fatigue Questionnaire : Abdomen pain	Worsen	2.8
DePaul University Fatigue Questionnaire : Allergies	Worsen	3.32
DePaul University Fatigue Questionnaire : Anxiety/tension	Worsen	2.8
DePaul University Fatigue Questionnaire : Depression	Worsen	2.8
DePaul University Fatigue Questionnaire : Difficulty falling asleep	Worsen	3.49
DePaul University Fatigue Questionnaire : Difficulty finding the right word	Worsen	2.72
DePaul University Fatigue Questionnaire : Fatigue	Worsen	1.06
DePaul University Fatigue Questionnaire : Forgetting what you are trying to say	Worsen	2.8
DePaul University Fatigue Questionnaire : Impaired Memory & concentration	Improves	-2.17
DePaul University Fatigue Questionnaire : Walking up early in the morning (e.g. 3AM)	Worsen	2.36
Immune Manifestations: Inflammation (General)	Improves	-3.24
Infection: Human Herpesvirus 6 (HHV6)	Improves	-2.17
Infection: Mycoplasma	Improves	-2.17
Joint: Tenderness	Improves	-2.97
Neuroendocrine Manifestations: Excessive adrenaline	Improves	-2.9
Neurological-Vision: inability to focus eye/vision	Improves	-2.91
Neurological: Confusion	Worsen	2.97
Neurological: Seasonal Affective Disorder (SAD)	Improves	-2.17
Official Diagnosis: Allergic Rhinitis (Hay Fever)	Worsen	1.74
Official Diagnosis: Autoimmune Disease	Improves	-2.97
Pain: Sensitivity to pain	Worsen	1.71

Published Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is according to the microbiome shifts reported in studies. Clinical studies may show different results

Symptom	Impact	Predictor of Bacteria Shift
Acne	Worsen	0
ADHD	Improves	-3.96
Allergic Rhinitis (Hay Fever)	Improves	-3.09
Allergies	Worsen	1.74
Alzheimer's disease	Worsen	4.01
Amyotrophic lateral sclerosis (ALS) Motor Neuron	Worsen	2.88
Ankylosing spondylitis	Improves	-3.23
Asthma	Improves	-4.24
Atherosclerosis	Worsen	3.81
Autism	Worsen	3.54
Barrett esophagus cancer	Worsen	1.46
Bipolar Disorder	Improves	-2.97
Brain Trauma	Improves	-2.72
Carcinoma	Worsen	2.69
Celiac Disease	Worsen	2.97
Cerebral Palsy	Improves	-2.9
Chronic Fatigue Syndrome	Improves	-4.78
Chronic Kidney Disease	Improves	-2.72
Chronic Urticaria (Hives)	Improves	-2.9
Colorectal Cancer	Improves	-4.08
Coronary artery disease	Improves	-1.42
Crohn's Disease	Improves	-2.47
Depression	Improves	-4.44
Epilepsy	Improves	-3.96
Fibromyalgia	Improves	-4.22
Functional constipation / chronic idiopathic constipation	Improves	-2.46
gallstone disease (gsd)	Worsen	2.88
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus	Worsen	2.43
Graves' disease	Worsen	3.94
Hashimoto's thyroiditis	Improves	-2.8
High Blood Pressure	Improves	-2.73
Histamine Issues	Worsen	1.84
Histamine Issues From Ubiome	Improves	-2.72
hypercholesterolemia (High Cholesterol)	Improves	-2.69
Hyperlipidemia (High Blood Fats)	Worsen	2.09
IgA nephropathy (IgAN)	Worsen	3.11
Inflammatory Bowel Disease	Worsen	3.94
Irritable Bowel Syndrome	Improves	-3.87
Liver Cirrhosis	Worsen	4.47
ME/CFS with IBS	Improves	-3.6
ME/CFS without IBS	Improves	-3.99
Mood Disorders	Improves	-2.97
Multiple Sclerosis	Worsen	4.09
Multiple system atrophy (MSA)	Worsen	1.93
neuropsychiatric disorders (PANDAS, PANS)	Improves	-2.97
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic	Worsen	3.09
NonCeliac Gluten Sensitivity	Worsen	2.06
Obesity	Worsen	3.57
Osteoarthritis	Improves	-2.9
Osteoporosis	Worsen	2.81
Parkinson's Disease	Improves	-3.3
Psoriasis	Worsen	2.8
rheumatoid arthritis (RA),Spondyloarthritis (SpA)	Improves	-1.32
Rosacea	Improves	-2.29
Schizophrenia	Worsen	3.87
Sjögren syndrome	Worsen	2.97
Small Intestinal Bacterial Overgrowth (SIBO)	Improves	-2.5
Stress / posttraumatic stress disorder	Improves	-2.97
Systemic Lupus Erythematosus	Improves	-3.52
Type 1 Diabetes	Improves	-3.95
Type 2 Diabetes	Improves	-2.21
Ulcerative colitis	Worsen	3.41

Bacteria Impacted

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.