🍽️ ß-sitosterol

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  1. Cholesterol Reduction: Beta-sitosterol is known to inhibit the absorption of cholesterol in the intestine, leading to a reduction in low-density lipoprotein (LDL) cholesterol levels in the blood. LDL cholesterol is often referred to as "bad" cholesterol because high levels of LDL cholesterol are associated with an increased risk of cardiovascular diseases such as coronary artery disease, heart attack, and stroke. By lowering LDL cholesterol levels, beta-sitosterol may help reduce the risk of cardiovascular events.

  2. Triglyceride Reduction: In addition to lowering LDL cholesterol, beta-sitosterol may also have modest effects on reducing triglyceride levels in the blood. Elevated triglyceride levels are another risk factor for cardiovascular disease, and lowering triglyceride levels may contribute to overall cardiovascular health.

  3. Anti-Inflammatory Properties: Beta-sitosterol exhibits anti-inflammatory properties, which may benefit individuals with inflammatory conditions such as arthritis, inflammatory bowel disease (IBD), or cardiovascular disease. By reducing inflammation in the body, beta-sitosterol may help mitigate the progression of these conditions and improve overall health.

  4. Immune Modulation: Some research suggests that beta-sitosterol may modulate the immune system and enhance immune function, potentially reducing the risk of infections and supporting overall immune health.

  5. Prostate Health: Beta-sitosterol has been studied for its potential benefits in promoting prostate health and alleviating symptoms of benign prostatic hyperplasia (BPH), a non-cancerous enlargement of the prostate gland that can cause urinary symptoms such as frequent urination, urgency, and incomplete bladder emptying. Some studies suggest that beta-sitosterol may help improve urinary flow rate and reduce BPH-related symptoms.

  6. Antioxidant Activity: Beta-sitosterol exhibits antioxidant activity, which may help protect against oxidative stress and damage caused by free radicals. Oxidative stress is implicated in the development of various chronic diseases, including cardiovascular disease, cancer, and neurodegenerative disorders. By scavenging free radicals and neutralizing oxidative stress, beta-sitosterol may contribute to overall health and disease prevention.

  7. Blood Sugar Regulation: Some research suggests that beta-sitosterol may have beneficial effects on blood sugar regulation and insulin sensitivity, which could be particularly relevant for individuals with diabetes or metabolic syndrome. By improving insulin sensitivity and glucose metabolism, beta-sitosterol may help maintain stable blood sugar levels and reduce the risk of diabetes-related complications.

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Impacted of ß-sitosterol On Probiotics

Rank Probiotic Impact

Bacteria Impacted by ß-sitosterol

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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Taxonomy Rank Effect Citations Notation
Coriobacteriaceae family Decreases 📓 Source Study Associated with Iron Deficiency (Low)
Collinsella genus Decreases 📓 Source Study proinflammatory
Enorma genus Decreases 📓 Source Study
Coriobacterium genus Decreases 👶 Source Study
Olegusella genus Decreases 👶 Source Study
Parvibacter genus Decreases 👶 Source Study
Senegalimassilia genus Decreases 👶 Source Study
environmental samples no rank Decreases 👶 Source Study
environmental samples no rank Decreases 👶 Source Study
unclassified Collinsella no rank Decreases 👶 Source Study
unclassified Coriobacteriaceae no rank Decreases 👶 Source Study
[Collinsella] massiliensis species Decreases 📓 Source Study
Collinsella aerofaciens species Decreases 📓 Source Study
Collinsella intestinalis species Decreases 📓 Source Study
Collinsella tanakaei species Decreases 📓 Source Study
[Collinsella] massiliensis species Decreases ⚗️ Source Study
Collinsella sp. 4_8_47FAA species Decreases 👶 Source Study
Enorma sp. species Decreases 👶 Source Study
Parvibacter caecicola species Decreases ⚗️ Source Study
Collinsella bouchesdurhonensis species Decreases 👶 Source Study
Collinsella phocaeensis species Decreases 👶 Source Study
Collinsella provencensis species Decreases 👶 Source Study
Collinsella sp. species Decreases 👶 Source Study
Collinsella sp. AM34-10 species Decreases 👶 Source Study
Collinsella stercoris species Decreases 👶 Source Study
Enorma massiliensis species Decreases 👶 Source Study
Enorma timonensis species Decreases 👶 Source Study
Collinsella aerofaciens ATCC 25986 strain Decreases 👶 Source Study
Collinsella intestinalis DSM 13280 strain Decreases 👶 Source Study
Collinsella tanakaei YIT 12063 strain Decreases 👶 Source Study
Coriobacterineae suborder Decreases ⚗️ Source Study

Impact of ß-sitosterol on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Allergies 0.5 0.5
Alopecia (Hair Loss) 0.5 0.5
Alzheimer's disease 0.5 0.5
Ankylosing spondylitis 0.5 0.5
Atherosclerosis 0.5 0.5
Atrial fibrillation 0.5 0.5
Autism 0.5 0.5
Barrett esophagus cancer 0.5 0.5
Brain Trauma 0.5 0.5
Carcinoma 0.5 0.5 0
Celiac Disease 0.2 -0.2
Chronic Kidney Disease 0.5 -0.5
Colorectal Cancer 0.5 -0.5
Coronary artery disease 0.5 0.5
COVID-19 0.5 1 -1
Crohn's Disease 0.5 0.5 0
Depression 0.4 1 -1.5
Endometriosis 0.5 0.5
Epilepsy 0.5 0.5
erectile dysfunction 0.2 0.2
Graves' disease 1 0.5 1
hypercholesterolemia (High Cholesterol) 0.5 0.5
hyperglycemia 0.5 0.5
Hyperlipidemia (High Blood Fats) 0.5 0.5 0
hypertension (High Blood Pressure 0.5 0.5
Inflammatory Bowel Disease 0.5 0.5 0
Intelligence 0.5 -0.5
Intracranial aneurysms 0.5 -0.5
Long COVID 1 1.5 -0.5
Metabolic Syndrome 1.5 1.5
Mood Disorders 0.9 1 -0.11
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 0.5 0.5
Obesity 1.5 0.5 2
pancreatic cancer 0.2 -0.2
Parkinson's Disease 0.5 0.5
Premenstrual dysphoric disorder 0.5 0.5
primary biliary cholangitis 0.5 -0.5
Psoriasis 0.5 0.5
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 1 0.5 1
Schizophrenia 0.5 0.5
Stress / posttraumatic stress disorder 0.5 0.7 -0.4
Tic Disorder 0.5 -0.5
Type 2 Diabetes 1.5 1.5
Unhealthy Ageing 0.5 -0.5

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