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Cholesterol Lowering: Stigmastanol is known to inhibit the absorption of cholesterol in the intestine, leading to a reduction in low-density lipoprotein (LDL) cholesterol levels in the blood. LDL cholesterol is often referred to as "bad" cholesterol because high levels of LDL cholesterol are associated with an increased risk of cardiovascular diseases such as coronary artery disease, heart attack, and stroke. By lowering LDL cholesterol levels, stigmastanol may help reduce the risk of cardiovascular events.
Triglyceride Reduction: In addition to lowering LDL cholesterol, stigmastanol may also have modest effects on reducing triglyceride levels in the blood. Elevated triglyceride levels are another risk factor for cardiovascular disease, and lowering triglyceride levels may contribute to overall cardiovascular health.
Anti-Inflammatory Properties: Some research suggests that stigmastanol may possess anti-inflammatory properties, which could potentially benefit individuals with inflammatory conditions such as arthritis, inflammatory bowel disease (IBD), or cardiovascular disease. By reducing inflammation in the body, stigmastanol may help mitigate the progression of these conditions and improve overall health.
Antioxidant Activity: Stigmastanol exhibits antioxidant activity, which may help protect against oxidative stress and damage caused by free radicals. Oxidative stress is implicated in the development of various chronic diseases, including cardiovascular disease, cancer, and neurodegenerative disorders. By scavenging free radicals and neutralizing oxidative stress, stigmastanol may contribute to overall health and disease prevention.
Blood Sugar Regulation: Some studies suggest that stigmastanol may have beneficial effects on blood sugar regulation and insulin sensitivity, which could be particularly relevant for individuals with diabetes or metabolic syndrome. By improving insulin sensitivity and glucose metabolism, stigmastanol may help maintain stable blood sugar levels and reduce the risk of diabetes-related complications.
Digestive Health: Stigmastanol may also have positive effects on digestive health, including promoting regular bowel movements and supporting a healthy gut microbiota. A healthy gut microbiota is associated with numerous health benefits, including improved digestion, nutrient absorption, immune function, and overall well-being.
Bone Health: Preliminary research suggests that stigmastanol may play a role in promoting bone health and reducing the risk of osteoporosis, although further studies are needed to confirm these potential benefits.
| Rank | Probiotic | Impact |
|---|
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
| Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
|---|---|---|---|
| Allergies | 0.5 | 0.5 | |
| Alopecia (Hair Loss) | 0.5 | 0.5 | |
| Alzheimer's disease | 0.5 | 0.5 | |
| Ankylosing spondylitis | 0.5 | 0.5 | |
| Atherosclerosis | 0.5 | 0.5 | |
| Atrial fibrillation | 0.5 | 0.5 | |
| Autism | 0.5 | 0.5 | |
| Barrett esophagus cancer | 0.5 | 0.5 | |
| Brain Trauma | 0.5 | 0.5 | |
| Carcinoma | 0.5 | 0.5 | 0 |
| Celiac Disease | 0.2 | -0.2 | |
| Chronic Kidney Disease | 0.5 | -0.5 | |
| Colorectal Cancer | 0.5 | -0.5 | |
| Coronary artery disease | 0.5 | 0.5 | |
| COVID-19 | 0.5 | 1 | -1 |
| Crohn's Disease | 0.5 | 0.5 | 0 |
| Depression | 0.4 | 1 | -1.5 |
| Endometriosis | 0.5 | 0.5 | |
| Epilepsy | 0.5 | 0.5 | |
| erectile dysfunction | 0.2 | 0.2 | |
| Graves' disease | 1 | 0.5 | 1 |
| hypercholesterolemia (High Cholesterol) | 0.5 | 0.5 | |
| hyperglycemia | 0.5 | 0.5 | |
| Hyperlipidemia (High Blood Fats) | 0.5 | 0.5 | 0 |
| hypertension (High Blood Pressure | 0.5 | 0.5 | |
| Inflammatory Bowel Disease | 0.5 | 0.5 | 0 |
| Intelligence | 0.5 | -0.5 | |
| Intracranial aneurysms | 0.5 | -0.5 | |
| Long COVID | 1 | 1.5 | -0.5 |
| Metabolic Syndrome | 1.5 | 1.5 | |
| Mood Disorders | 0.9 | 1 | -0.11 |
| Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | 0.5 | 0.5 | |
| Obesity | 1.5 | 0.5 | 2 |
| pancreatic cancer | 0.2 | -0.2 | |
| Parkinson's Disease | 0.5 | 0.5 | |
| Premenstrual dysphoric disorder | 0.5 | 0.5 | |
| primary biliary cholangitis | 0.5 | -0.5 | |
| Psoriasis | 0.5 | 0.5 | |
| rheumatoid arthritis (RA),Spondyloarthritis (SpA) | 1 | 0.5 | 1 |
| Schizophrenia | 0.5 | 0.5 | |
| Stress / posttraumatic stress disorder | 0.5 | 0.7 | -0.4 |
| Tic Disorder | 0.5 | -0.5 | |
| Type 2 Diabetes | 1.5 | 1.5 | |
| Unhealthy Ageing | 0.5 | -0.5 |
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