We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.
This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.
Symptom | Impact | Predictor of Bacteria Shift |
---|---|---|
Age: 20-30 | Improves | -2.95 |
Age: 60-70 | Worsen | 4.02 |
Asymptomatic: Minor Health Issues (a few symptoms only) | Improves | -3.62 |
Asymptomatic: No Health Issues | Improves | -2.94 |
Autism: Official Diagnosis | Worsen | 4.16 |
Autonomic Manifestations: Cortisol disorders or irregularity | Worsen | 3.05 |
Autonomic Manifestations: irritable bowel syndrome | Improves | -2.11 |
Autonomic Manifestations: Orthostatic intolerance | Improves | -2.31 |
Autonomic Manifestations: palpitations | Improves | -2.63 |
Autonomic Manifestations: Postural orthostatic tachycardia syndrome (POTS) | Worsen | 2.63 |
Autonomic: Dizziness or fainting | Improves | -1.99 |
Autonomic: Graying or blacking out after standing | Improves | -2.36 |
Autonomic: Heart rate increase after standing | Improves | -1.13 |
Autonomic: Inability to tolerate an upright position | Worsen | 4.07 |
Autonomic: Irregular heartbeats | Worsen | 4.05 |
Autonomic: Shortness of breath | Improves | -2 |
Blood Type: A Positive | Worsen | 3.93 |
Blood Type: O Positive | Worsen | 4.15 |
Comorbid-Mouth: Bruxism - Jaw cleanching / Teeth grinding | Worsen | 4.1 |
Comorbid-Mouth: Dry Mouth | Improves | -3.27 |
Comorbid-Mouth: Mouth Sores | Improves | -1.84 |
Comorbid-Mouth: TMJ / Dysfunction of the temporomandibular joint syndrome | Worsen | 4.77 |
Comorbid: Constipation and Explosions (not diarrohea) | Worsen | 4.99 |
Comorbid: Fibromyalgia | Worsen | 1.64 |
Comorbid: High Anxiety | Worsen | 4.3 |
Comorbid: Histamine or Mast Cell issues | Worsen | 4.32 |
Comorbid: Hypothyroidism | Worsen | 4.62 |
Comorbid: Inflammatory bowel disease | Worsen | 4.17 |
Comorbid: Migraine | Worsen | 2.7 |
Comorbid: Mold Sensitivity / Exposure | Worsen | 3.05 |
Comorbid: Multiple Chemical Sensitivity | Improves | -2.64 |
Comorbid: Snoring (NOT Sleep Apnea | Worsen | 5.01 |
Condition: ME/CFS with IBS | Worsen | 3.01 |
DePaul University Fatigue Questionnaire : Allergies | Worsen | 3.69 |
DePaul University Fatigue Questionnaire : Anxiety/tension | Worsen | 3.72 |
DePaul University Fatigue Questionnaire : Difficulty staying asleep | Worsen | 2.45 |
DePaul University Fatigue Questionnaire : Fatigue | Worsen | 4.51 |
DePaul University Fatigue Questionnaire : Forgetting what you are trying to say | Worsen | 1.15 |
DePaul University Fatigue Questionnaire : Impaired Memory & concentration | Worsen | 4.55 |
DePaul University Fatigue Questionnaire : Unrefreshing Sleep, that is waking up feeling tired | Worsen | 4.4 |
DePaul University Fatigue Questionnaire : Walking up early in the morning (e.g. 3AM) | Worsen | 3.3 |
Gender: Male | Worsen | 1.27 |
General: Depression | Worsen | 1.71 |
General: Fatigue | Improves | -2.7 |
General: Headaches | Improves | -1.26 |
General: Myalgia (pain) | Improves | -3.49 |
General: Sinus issues with headaches | Worsen | 3.44 |
Immune Manifestations: Abdominal Pain | Worsen | 3.8 |
Immune Manifestations: Alcohol Intolerant | Worsen | 3.82 |
Immune Manifestations: Bloating | Worsen | 2.95 |
Immune Manifestations: Diarrhea | Worsen | 1.93 |
Immune Manifestations: Hair loss | Improves | -1.9 |
Immune Manifestations: Inflammation (General) | Worsen | 3.77 |
Immune Manifestations: medication sensitivities. | Worsen | 3.05 |
Immune Manifestations: Mucus in the stool | Worsen | 3.29 |
Immune Manifestations: new food sensitivities | Improves | -1.9 |
Immune Manifestations: tender lymph nodes | Improves | -2.9 |
Immune: Recurrent Sore throat | Improves | -1.48 |
Infection: Human Herpesvirus 6 (HHV6) | Worsen | 4.27 |
Infection: Mycoplasma | Worsen | 3.84 |
Infection: Parasite - Other | Worsen | 4.06 |
Joint: Redness | Worsen | 3.2 |
Joint: Stiffness and swelling | Worsen | 3.99 |
Joint: Tenderness | Worsen | 3.21 |
Neurocognitive: Brain Fog | Worsen | 2.95 |
Neurocognitive: Can only focus on one thing at a time | Worsen | 1.88 |
Neurocognitive: Difficulty paying attention for a long period of time | Worsen | 2.95 |
Neurocognitive: Difficulty understanding things | Worsen | 1.26 |
Neurocognitive: Problems remembering things | Worsen | 2.95 |
Neurocognitive: Unable to focus vision and/or attention | Worsen | 4.38 |
Neuroendocrine Manifestations: Air Hunger | Worsen | 1.93 |
Neuroendocrine Manifestations: Dry Eye (Sicca or Sjogren Syndrome) | Worsen | 2.82 |
Neuroendocrine Manifestations: Excessive adrenaline | Worsen | 3.38 |
Neuroendocrine Manifestations: intolerance of extremes of heat and cold | Worsen | 2.54 |
Neuroendocrine Manifestations: marked weight change | Improves | -2.96 |
Neuroendocrine Manifestations: Paraesthesia (tingling burning of skin) | Worsen | 3.25 |
Neuroendocrine Manifestations: Rapid muscular fatiguability | Improves | -3.07 |
Neuroendocrine Manifestations: subnormal body temperature | Worsen | 3.72 |
Neuroendocrine Manifestations: sweating episodes | Worsen | 3.16 |
Neuroendocrine: Alcohol intolerance | Worsen | 4.56 |
Neuroendocrine: Cold limbs (e.g. arms, legs hands) | Improves | -3.2 |
Neuroendocrine: Feeling hot or cold for no reason | Worsen | 2.72 |
Neuroendocrine: Feeling like you have a high temperature | Improves | -2.63 |
Neuroendocrine: Lost or gained weight without trying | Improves | -2.27 |
Neurological-Audio: Tinnitus (ringing in ear) | Worsen | 3.62 |
Neurological-Sleep: Chaotic diurnal sleep rhythms (Erratic Sleep) | Worsen | 0.7 |
Neurological-Sleep: Insomnia | Worsen | 3.24 |
Neurological-Sleep: Night Sweats | Improves | -3.07 |
Neurological-Sleep: Sleep Apnea | Worsen | 3.2 |
Neurological-Sleep: Vivid Dreams/Nightmares | Improves | -2.69 |
Neurological-Vision: Blurred Vision | Improves | -2.24 |
Neurological-Vision: inability to focus eye/vision | Worsen | 4.34 |
Neurological-Vision: photophobia (Light Sensitivity) | Worsen | 4.77 |
Neurological: Cognitive/Sensory Overload | Worsen | 2.94 |
Neurological: Difficulty processing information (Understanding) | Worsen | 1.01 |
Neurological: Difficulty reading | Worsen | 4.33 |
Neurological: Disorientation | Improves | -2.95 |
Neurological: Dysautonomia | Worsen | 1.6 |
Neurological: emotional overload | Worsen | 3.78 |
Neurological: Executive Decision Making (Difficulty making) | Improves | -2.75 |
Neurological: fasciculations | Worsen | 3.23 |
Neurological: Joint hypermobility | Worsen | 4.13 |
Neurological: Seasonal Affective Disorder (SAD) | Worsen | 1.49 |
Neurological: Short-term memory issues | Worsen | 2.25 |
Neurological: Slowed speech | Improves | -2.2 |
Neurological: Spatial instability and disorientation | Improves | -2.95 |
Official Diagnosis: Allergic Rhinitis (Hay Fever) | Worsen | 4.91 |
Official Diagnosis: Autoimmune Disease | Worsen | 0.42 |
Official Diagnosis: Chronic Fatigue Syndrome | Improves | -2.95 |
Official Diagnosis: Irritable Bowel Syndrome | Worsen | 3.76 |
Official Diagnosis: Mast Cell Dysfunction | Worsen | 4.64 |
Onset: 2010-2020 | Worsen | 4.4 |
Onset: Gradual | Improves | -2.88 |
Other: Sensitivity to mold | Worsen | 1.64 |
Other: Sensitivity to vibrations | Worsen | 2.74 |
Pain: Aching of the eyes or behind the eyes | Improves | -2.02 |
Pain: Chest pain | Improves | -2.73 |
Pain: Eye pain | Improves | -3.15 |
Pain: Myofascial pain | Improves | -2.55 |
Pain: Sensitivity to pain | Worsen | 3.33 |
Post-exertional malaise: Difficulty reading after mild physical or mental activity | Worsen | 3.63 |
Post-exertional malaise: General | Worsen | 2.61 |
Post-exertional malaise: Mentally tired after the slightest effort | Improves | -2.95 |
Post-exertional malaise: Rapid cognitive fatigability, | Worsen | 3.58 |
Post-exertional malaise: Rapid muscular fatigability, | Worsen | 2.22 |
Post-exertional malaise: Worsening of symptoms after mild mental activity | Worsen | 3.47 |
Post-exertional malaise: Worsening of symptoms after mild physical activity | Improves | -2.02 |
Sleep: Daytime drowsiness | Worsen | 2.95 |
Sleep: Problems staying asleep | Improves | -1.7 |
Sleep: Waking up early in the morning (e.g. 3 AM) | Worsen | 3.76 |
We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.
This is according to the microbiome shifts reported in studies. Clinical studies may show different results
Symptom | Impact | Predictor of Bacteria Shift |
---|---|---|
Acne | Improves | -3.65 |
ADHD | Improves | -3.98 |
Allergies | Improves | -3.47 |
Alzheimer's disease | Improves | -4.95 |
Amyotrophic lateral sclerosis (ALS) Motor Neuron | Improves | -0.84 |
Ankylosing spondylitis | Worsen | 4.83 |
Asthma | Worsen | 2.65 |
Atherosclerosis | Worsen | 5.17 |
Autism | Improves | -5.25 |
Barrett esophagus cancer | Improves | -2.93 |
Brain Trauma | Improves | -3.2 |
Carcinoma | Improves | -2.54 |
Celiac Disease | Improves | -3.69 |
Chronic Fatigue Syndrome | Improves | -0.75 |
Chronic Kidney Disease | Improves | -4.54 |
Chronic urticaria (Hives) | Worsen | 2.33 |
Colorectal Cancer | Improves | -3.51 |
Coronary artery disease | Improves | -3.89 |
Crohn's Disease | Improves | -5.04 |
Depression | Worsen | 3.6 |
Epilepsy | Improves | -3.46 |
Fibromyalgia | Improves | -1.37 |
Functional constipation / chronic idiopathic constipation | Improves | -3.92 |
gallstone disease (gsd) | Worsen | 3.56 |
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus | Improves | -4.08 |
Generalized anxiety disorder | Improves | -3.67 |
Gout | Worsen | 3.26 |
Hashimoto's thyroiditis | Worsen | 3.04 |
High Blood Pressure | Improves | -4.4 |
Histamine Issues | Worsen | 1.84 |
Histamine Issues From Ubiome | Improves | -2.11 |
hypercholesterolemia (High Cholesterol) | Improves | -1.86 |
Hyperlipidemia (High Blood Fats) | Improves | -4.15 |
hypertension (High Blood Pressure | Worsen | 1.56 |
IgA nephropathy (IgAN) | Improves | -3.08 |
Inflammatory Bowel Disease | Improves | -4.96 |
Insomnia | Improves | -2.85 |
Irritable Bowel Syndrome | Improves | -4.03 |
Liver Cirrhosis | Improves | -0.09 |
ME/CFS with IBS | Improves | -3.27 |
ME/CFS without IBS | Worsen | 4.03 |
Metabolic Syndrome | Improves | -3.01 |
Multiple Sclerosis | Improves | -3.15 |
Multiple system atrophy (MSA) | Worsen | 3.52 |
neuropsychiatric disorders (PANDAS, PANS) | Improves | -3.02 |
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | Improves | -3.41 |
Obesity | Improves | -4.04 |
Osteoporosis | Improves | -2.24 |
Parkinson's Disease | Improves | -2.84 |
Psoriasis | Improves | -3.64 |
Rheumatoid arthritis | Improves | -3.84 |
rheumatoid arthritis (RA),Spondyloarthritis (SpA) | Improves | -3.7 |
Rosacea | Improves | -3.28 |
Schizophrenia | Worsen | 3.38 |
Sclerosis | Improves | -3.45 |
Sjögren syndrome | Worsen | 4.01 |
Stress / posttraumatic stress disorder | Worsen | 4.46 |
Systemic Lupus Erythematosus | Improves | -3.01 |
Type 1 Diabetes | Improves | -4.45 |
Type 2 Diabetes | Improves | -2 |
Ulcerative colitis | Worsen | 4.69 |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.