We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.
This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.
Symptom | Impact | Predictor of Bacteria Shift |
---|---|---|
Asymptomatic: No Health Issues | Improves | -1.6 |
Autism: Official Diagnosis | Worsen | 1.9 |
Autonomic Manifestations: Cortisol disorders or irregularity | Worsen | 3.05 |
Autonomic: Heart rate increase after standing | Worsen | 3.05 |
Comorbid-Mouth: Dry Mouth | Worsen | 2.74 |
Comorbid-Mouth: TMJ / Dysfunction of the temporomandibular joint syndrome | Worsen | 1.9 |
Comorbid: Constipation and Explosions (not diarrohea) | Worsen | 1.9 |
Comorbid: High Anxiety | Worsen | 1.9 |
Comorbid: Hypothyroidism | Worsen | 1.9 |
Comorbid: Mold Sensitivity / Exposure | Worsen | 3.05 |
DePaul University Fatigue Questionnaire : Fatigue | Worsen | 3.2 |
DePaul University Fatigue Questionnaire : Impaired Memory & concentration | Worsen | 2.93 |
General: Myalgia (pain) | Worsen | 3.05 |
Immune Manifestations: medication sensitivities. | Worsen | 3.05 |
Immune Manifestations: Mucus in the stool | Worsen | 3.2 |
Immune Manifestations: new food sensitivities | Improves | -1.9 |
Immune Manifestations: tender lymph nodes | Improves | -2.9 |
Infection: Mycoplasma | Worsen | 1.9 |
Infection: Parasite - Other | Worsen | 1.9 |
Neuroendocrine Manifestations: Excessive adrenaline | Worsen | 3.64 |
Neuroendocrine: Feeling like you have a low temperature | Worsen | 2.74 |
Neurological-Sleep: Insomnia | Worsen | 1.9 |
Neurological: Difficulty processing information (Understanding) | Worsen | 3.05 |
Neurological: emotional overload | Worsen | 3.57 |
Neurological: fasciculations | Worsen | 2.74 |
Neurological: High degree of Empathy before onset | Worsen | 2.74 |
Neurological: Impairment of concentration | Worsen | 3.05 |
Neurological: Joint hypermobility | Worsen | 3.2 |
Neurological: Short-term memory issues | Worsen | 3.57 |
Neurological: Spatial instability and disorientation | Worsen | 2.74 |
Official Diagnosis: Irritable Bowel Syndrome | Worsen | 1.9 |
Onset: less than 02 years since onset | Worsen | 2.74 |
Post-exertional malaise: Difficulty reading after mild physical or mental activity | Worsen | 2.93 |
Post-exertional malaise: General | Worsen | 2.74 |
Post-exertional malaise: Mentally tired after the slightest effort | Worsen | 3.48 |
Post-exertional malaise: Physically drained or sick after mild activity | Worsen | 3.57 |
Post-exertional malaise: Post-exertional malaise | Worsen | 2.74 |
Post-exertional malaise: Rapid cognitive fatigability, | Worsen | 3.57 |
Post-exertional malaise: Worsening of symptoms after mild mental activity | Worsen | 2.74 |
We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.
This is according to the microbiome shifts reported in studies. Clinical studies may show different results
Symptom | Impact | Predictor of Bacteria Shift |
---|---|---|
Cerebral Palsy | Worsen | 3.15 |
Acne | Improves | -2.88 |
ADHD | Worsen | 2.88 |
Allergies | Improves | -1.28 |
Alzheimer's disease | Improves | -3.56 |
Amyotrophic lateral sclerosis (ALS) Motor Neuron | Worsen | 3.51 |
Ankylosing spondylitis | Worsen | 4.45 |
Asthma | Worsen | 3.9 |
Atherosclerosis | Worsen | 4.18 |
Autism | Improves | -4.48 |
Brain Trauma | Improves | -2.74 |
Carcinoma | Worsen | 0 |
Celiac Disease | Improves | -3.63 |
Chronic Fatigue Syndrome | Improves | -3.63 |
Chronic urticaria (Hives) | Worsen | 2.9 |
Colorectal Cancer | Worsen | 2.73 |
Crohn's Disease | Improves | -3.26 |
Depression | Improves | -2.56 |
Epilepsy | Improves | -3.39 |
Fibromyalgia | Improves | -2.85 |
gallstone disease (gsd) | Worsen | 2.95 |
Generalized anxiety disorder | Improves | -2.54 |
Graves' disease | Worsen | 2.74 |
Hashimoto's thyroiditis | Worsen | 0.63 |
High Blood Pressure | Worsen | 2.54 |
Histamine Issues | Improves | -2.75 |
Hyperlipidemia (High Blood Fats) | Worsen | 2.88 |
IgA nephropathy (IgAN) | Improves | -3.63 |
Inflammatory Bowel Disease | Improves | -4.07 |
Irritable Bowel Syndrome | Improves | -4.11 |
Liver Cirrhosis | Improves | -2.16 |
ME/CFS with IBS | Improves | -1.85 |
ME/CFS without IBS | Worsen | 1.85 |
Mood Disorders | Improves | -2.74 |
Multiple Sclerosis | Worsen | 2.95 |
Multiple system atrophy (MSA) | Improves | -2.88 |
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | Worsen | 0.26 |
Obesity | Improves | -2.51 |
Osteoporosis | Worsen | 2.9 |
Parkinson's Disease | Worsen | 3.36 |
Psoriasis | Worsen | 3.15 |
Rheumatoid arthritis | Improves | -3.88 |
rheumatoid arthritis (RA),Spondyloarthritis (SpA) | Worsen | 1.82 |
Rosacea | Improves | -0.26 |
Schizophrenia | Worsen | 2.73 |
Sclerosis | Improves | -2.9 |
Sjögren syndrome | Improves | -2.88 |
Small Intestinal Bacterial Overgrowth (SIBO) | Improves | -2.54 |
Stress / posttraumatic stress disorder | Improves | -3.41 |
Systemic Lupus Erythematosus | Worsen | 1.38 |
Type 1 Diabetes | Improves | -3.05 |
Type 2 Diabetes | Worsen | 0.97 |
Ulcerative colitis | Improves | -2.2 |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.