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Citizen Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.

SymptomImpactPredictor of Bacteria Shift
Age: 60-70Improves-3.18
Asymptomatic: No Health IssuesWorsen2.31
Autism: Official DiagnosisImproves-3.77
Autonomic Manifestations: cardiac arrhythmiasWorsen3.5
Autonomic: Inability to tolerate an upright positionWorsen3.05
Autonomic: Irregular heartbeatsWorsen2.75
Autonomic: Shortness of breathWorsen1.67
Blood Type: A PositiveImproves-1.86
Blood Type: O PositiveImproves-3.89
Comorbid-Mouth: Bruxism - Jaw cleanching / Teeth grindingImproves-3.18
Comorbid-Mouth: Mouth SoresImproves-1.84
Comorbid-Mouth: TMJ / Dysfunction of the temporomandibular joint syndromeImproves-3.63
Comorbid: Constipation and Explosions (not diarrohea)Improves-3.14
Comorbid: FibromyalgiaWorsen0.35
Comorbid: High AnxietyImproves-3.14
Comorbid: Histamine or Mast Cell issuesImproves-3.77
Comorbid: HypothyroidismImproves-1.33
Comorbid: Inflammatory bowel disease Improves-2.13
Comorbid: MigraineImproves-1.86
Comorbid: Multiple Chemical SensitivityImproves-2.9
Comorbid: Snoring (NOT Sleep ApneaImproves-3.14
Condition: ME/CFS with IBSImproves-3.01
DePaul University Fatigue Questionnaire : AllergiesWorsen2.69
DePaul University Fatigue Questionnaire : FatigueWorsen2.19
DePaul University Fatigue Questionnaire : Impaired Memory & concentrationImproves-1.93
DePaul University Fatigue Questionnaire : Unrefreshing Sleep, that is waking up feeling tired Improves-3.69
General: DepressionImproves-1.71
General: HeadachesImproves-0.92
General: Sinus issues with headachesImproves-3.77
Immune Manifestations: Abdominal PainWorsen2.75
Immune Manifestations: Alcohol IntolerantImproves-3.18
Immune Manifestations: general malaiseImproves-1.88
Immune Manifestations: Hair lossWorsen1.9
Immune Manifestations: Mucus in the stoolWorsen3.05
Immune Manifestations: tender lymph nodesImproves-2.9
Immune: Sensitivity to smell/food/medication/chemicalsImproves-1.64
Infection: Epstein-Barr virusImproves-1.88
Infection: Human Herpesvirus 6 (HHV6)Worsen1.37
Infection: MycoplasmaWorsen1.33
Infection: Parasite - OtherImproves-2.87
Joint: Stiffness and swellingImproves-2.97
Joint: TendernessWorsen2.85
Neurocognitive: Can only focus on one thing at a timeImproves-1.88
Neurocognitive: Difficulty paying attention for a long period of timeImproves-1.88
Neurocognitive: Unable to focus vision and/or attentionImproves-3.77
Neuroendocrine Manifestations: cold extremitiesImproves-2.65
Neuroendocrine Manifestations: Excessive adrenalineWorsen1.68
Neuroendocrine Manifestations: intolerance of extremes of heat and coldImproves-3.55
Neuroendocrine Manifestations: Muscle weakness Improves-3.55
Neuroendocrine Manifestations: Paraesthesia (tingling burning of skin)Worsen3.05
Neuroendocrine Manifestations: subnormal body temperatureWorsen2.75
Neuroendocrine Manifestations: sweating episodesImproves-1.88
Neuroendocrine: Alcohol intoleranceImproves-2.93
Neuroendocrine: Cold limbs (e.g. arms, legs hands)Improves-1.71
Neuroendocrine: Lack of appetiteImproves-1.64
Neuroendocrine: Lost or gained weight without tryingImproves-1.64
Neurological-Audio: Tinnitus (ringing in ear)Improves-3.18
Neurological-Sleep: Chaotic diurnal sleep rhythms (Erratic Sleep)Improves-3.33
Neurological-Sleep: Sleep ApneaImproves-2.59
Neurological-Vision: inability to focus eye/visionImproves-3.77
Neurological-Vision: photophobia (Light Sensitivity)Improves-3.77
Neurological: Difficulty processing information (Understanding)Worsen1.67
Neurological: Difficulty readingImproves-3.18
Neurological: Joint hypermobilityWorsen3.05
Neurological: Seasonal Affective Disorder (SAD)Worsen1.49
Neurological: Short-term memory issuesImproves-2.87
Neurological: Slowed speechWorsen1.61
Official Diagnosis: Allergic Rhinitis (Hay Fever)Improves-3.14
Official Diagnosis: Mast Cell DysfunctionImproves-3.18
Onset: 2010-2020Improves-1.88
Onset: GradualImproves-1.67
Other: Sensitivity to moldImproves-1.64
Pain: Sensitivity to painImproves-2.97
Post-exertional malaise: Difficulty reading after mild physical or mental activityImproves-3.63
Sleep: Daytime drowsinessImproves-1.88
Sleep: Problems staying asleepWorsen1.7

Published Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is according to the microbiome shifts reported in studies. Clinical studies may show different results

SymptomImpactPredictor of Bacteria Shift
Cerebral PalsyWorsen0.34
AcneWorsen1.58
AllergiesImproves-3.51
Alzheimer's diseaseWorsen2.91
Amyotrophic lateral sclerosis (ALS) Motor NeuronImproves-3.51
Ankylosing spondylitisImproves-2.49
AsthmaImproves-2.9
AtherosclerosisWorsen3.77
AutismImproves-3.52
Barrett esophagus cancerWorsen3.63
Brain TraumaWorsen3.01
CarcinomaImproves-1.98
Celiac DiseaseImproves-2.89
Chronic Fatigue SyndromeImproves-3.79
Chronic Kidney DiseaseWorsen0.72
Chronic urticaria (Hives)Improves-2.87
Colorectal CancerImproves-4.05
Coronary artery disease Improves-0.73
Crohn's DiseaseWorsen4.15
DepressionImproves-4.71
EpilepsyImproves-4.03
FibromyalgiaImproves-3.25
Functional constipation / chronic idiopathic constipationWorsen1.48
gallstone disease (gsd)Worsen3.7
Gastroesophageal reflux disease (Gerd) including Barrett's esophagusWorsen3.82
GoutImproves-3.18
Graves' diseaseWorsen3.49
Hashimoto's thyroiditisWorsen0.6
High Blood PressureImproves-3.75
Histamine IssuesImproves-1.07
Histamine Issues From UbiomeWorsen1.61
hypercholesterolemia (High Cholesterol)Improves-3.44
Hyperlipidemia (High Blood Fats)Worsen3.51
IgA nephropathy (IgAN)Worsen1.67
Inflammatory Bowel DiseaseImproves-2.17
InsomniaWorsen3.7
Irritable Bowel SyndromeWorsen1.39
Liver CirrhosisWorsen3.69
ME/CFS with IBSImproves-3.64
ME/CFS without IBSImproves-3.72
Metabolic SyndromeImproves-2.9
Multiple SclerosisWorsen4.39
Multiple system atrophy (MSA)Worsen2.39
neuropsychiatric disorders (PANDAS, PANS)Worsen2.91
Nonalcoholic Fatty Liver Disease (nafld) NonalcoholicImproves-3.28
NonCeliac Gluten SensitivityWorsen1.48
ObesityImproves-4.97
OsteoporosisImproves-1.33
Parkinson's DiseaseWorsen5.05
PsoriasisImproves-2.47
Rheumatoid arthritisWorsen3.9
rheumatoid arthritis (RA),Spondyloarthritis (SpA)Worsen3.01
RosaceaWorsen1.9
SchizophreniaImproves-2.69
Sjögren syndromeWorsen1.65
Small Intestinal Bacterial Overgrowth (SIBO)Improves-2.83
Stress / posttraumatic stress disorderImproves-1.99
Systemic Lupus ErythematosusImproves-3.75
Type 1 DiabetesWorsen2.42
Type 2 DiabetesImproves-4.65
Ulcerative colitisImproves-3.43

Bacteria Impacted

Suggest a missed study:

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

📓 - direct citation | 👪 - Impacts Parent Taxa | 👶 - Impacts Child Taxa | 🧙 - Inferred
Taxonomy Rank Effect Citations
Bacteroidaceae family Decreases 📓 Source Study
Erysipelotrichaceae family Decreases 📓 Source Study
Ruminococcaceae family Decreases 📓 Source Study
Streptococcaceae family Decreases 📓 Source Study
Pasteurellaceae family Increases 📓 Source Study
Verrucomicrobiaceae family Increases 📓 Source Study
Bacteroides genus Decreases 📓 Source Study
Holdemania genus Decreases 📓 Source Study
Roseburia genus Decreases 📓 Source Study
Streptococcus genus Decreases 📓 Source Study
Absiella genus Decreases 👪 Source Study
Acetanaerobacterium genus Decreases 👪 Source Study
Agathobaculum genus Decreases 👪 Source Study
Anaerofilum genus Decreases 👪 Source Study
Anaeromassilibacillus genus Decreases 👪 Source Study
Anaerorhabdus genus Decreases 👪 Source Study
Angelakisella genus Decreases 👪 Source Study
Bittarella genus Decreases 👪 Source Study
Bulleidia genus Decreases 👪 Source Study
Candidatus Soleaferrea genus Decreases 👪 Source Study
Candidatus Stoquefichus genus Decreases 👪 Source Study
Caproiciproducens genus Decreases 👪 Source Study
Catenibacterium genus Decreases 👪 Source Study
Catenisphaera genus Decreases 👪 Source Study
Coprobacillus genus Decreases 👪 Source Study
Dielma genus Decreases 👪 Source Study
Eggerthia genus Decreases 👪 Source Study
Erysipelatoclostridium genus Decreases 👪 Source Study
Erysipelothrix genus Decreases 👪 Source Study
Ethanoligenens genus Decreases 👪 Source Study
Faecalibaculum genus Decreases 👪 Source Study
Faecalicoccus genus Decreases 👪 Source Study
Faecalitalea genus Decreases 👪 Source Study
Flavonifractor genus Decreases 👪 Source Study
Fournierella genus Decreases 👪 Source Study
Gemmiger genus Decreases 👪 Source Study
Gorbachella genus Decreases 👪 Source Study
Holdemanella genus Decreases 👪 Source Study
Hydrogenoanaerobacterium genus Decreases 👪 Source Study
Ileibacterium genus Decreases 👪 Source Study
Kandleria genus Decreases 👪 Source Study
Lactovum genus Decreases 👪 Source Study
Massilimicrobiota genus Decreases 👪 Source Study
Mediterranea genus Decreases 👪 Source Study
Merdibacter genus Decreases 👪 Source Study
Negativibacillus genus Decreases 👪 Source Study
Neglecta genus Decreases 👪 Source Study
Papillibacter genus Decreases 👪 Source Study
Phocea genus Decreases 👪 Source Study
Pseudoflavonifractor genus Decreases 👪 Source Study
Ruthenibacterium genus Decreases 👪 Source Study
Solobacterium genus Decreases 👪 Source Study
Sporobacter genus Decreases 👪 Source Study
Traorella genus Decreases 👪 Source Study
unclassified Erysipelotrichaceae genus Decreases 👪 Source Study
Actinobacillus genus Increases 👪 Source Study
Aggregatibacter genus Increases 👪 Source Study
Avibacterium genus Increases 👪 Source Study
Basfia genus Increases 👪 Source Study
Bibersteinia genus Increases 👪 Source Study
Bisgaardia genus Increases 👪 Source Study
Brevifollis genus Increases 👪 Source Study
Gallibacterium genus Increases 👪 Source Study
Glaesserella genus Increases 👪 Source Study
Haloferula genus Increases 👪 Source Study
Histophilus genus Increases 👪 Source Study
Luteolibacter genus Increases 👪 Source Study
Mannheimia genus Increases 👪 Source Study
Necropsobacter genus Increases 👪 Source Study
Nicoletella genus Increases 👪 Source Study
Otariodibacter genus Increases 👪 Source Study
Pasteurella genus Increases 👪 Source Study
Persicirhabdus genus Increases 👪 Source Study
Prosthecobacter genus Increases 👪 Source Study
Rodentibacter genus Increases 👪 Source Study
Roseimicrobium genus Increases 👪 Source Study
Ursidibacter genus Increases 👪 Source Study
Verrucomicrobium genus Increases 👪 Source Study
Volucribacter genus Increases 👪 Source Study
Akkermansia genus Increases 📓 Source Study
Blautia genus Increases 📓 Source Study
Haemophilus genus Increases 📓 Source Study
Firmicutes phylum Decreases 📓 Source Study
Bacteroides fragilis species Decreases 📓 Source Study
Holdemania filiformis species Decreases 📓 Source Study
Roseburia faecis species Decreases 📓 Source Study
ACM 3611 species Decreases 👪 Source Study
ATCC 19436 species Decreases 👪 Source Study
ATCC 29178 species Decreases 👪 Source Study
ATCC 43138 species Decreases 👪 Source Study
ATCC 49124 species Decreases 👪 Source Study
ATCC 51725 species Decreases 👪 Source Study
ATCC 700779 species Decreases 👪 Source Study
ATCC BAA-102 species Decreases 👪 Source Study
ATCC BAA-960 species Decreases 👪 Source Study
Bacteroides caecimuris species Decreases 👪 Source Study
Bacteroides coprosuis species Decreases 👪 Source Study
Bacteroides faecichinchillae species Decreases 👪 Source Study
Bacteroides galacturonicus species Decreases 👪 Source Study
Bacteroides heparinolyticus species Decreases 👪 Source Study
Bacteroides mediterraneensis Mailhe et al. 2016 species Decreases 👪 Source Study
Bacteroides sp. 1_1_14 species Decreases 👪 Source Study
Bacteroides sp. 1_1_30 species Decreases 👪 Source Study
Bacteroides sp. 1B2 species Decreases 👪 Source Study
Bacteroides sp. 2_1_22 species Decreases 👪 Source Study
Bacteroides sp. 2_1_33B species Decreases 👪 Source Study
Bacteroides sp. 2011_Ileo_VSA_D11 species Decreases 👪 Source Study
Bacteroides sp. 2011_Ileo_VSA_D8 species Decreases 👪 Source Study
Bacteroides sp. 265d species Decreases 👪 Source Study
Bacteroides sp. 3_1_19 species Decreases 👪 Source Study
Bacteroides sp. 3_1_33FAA species Decreases 👪 Source Study
Bacteroides sp. 3_2_5 species Decreases 👪 Source Study
Bacteroides sp. 314-4 species Decreases 👪 Source Study
Bacteroides sp. 31SF18 species Decreases 👪 Source Study
Bacteroides sp. 35BE34 species Decreases 👪 Source Study
Bacteroides sp. 35BE35 species Decreases 👪 Source Study
Bacteroides sp. 4_3_47FAA species Decreases 👪 Source Study
Bacteroides sp. 6-8 species Decreases 👪 Source Study
Bacteroides sp. 7853 species Decreases 👪 Source Study
Bacteroides sp. 9_1_42FAA species Decreases 👪 Source Study
Bacteroides sp. A1C1 species Decreases 👪 Source Study
Bacteroides sp. baku-33 species Decreases 👪 Source Study
Bacteroides sp. BLBE-2 species Decreases 👪 Source Study
Bacteroides sp. C13EG172 species Decreases 👪 Source Study
Bacteroides sp. D1 species Decreases 👪 Source Study
Bacteroides sp. D2 species Decreases 👪 Source Study
Bacteroides sp. D8 species Decreases 👪 Source Study
Bacteroides sp. dnLKV2 species Decreases 👪 Source Study
Bacteroides sp. dnLKV7 species Decreases 👪 Source Study
Bacteroides sp. ES-27 species Decreases 👪 Source Study
Bacteroides sp. HGA0134 species Decreases 👪 Source Study
Bacteroides sp. MANG species Decreases 👪 Source Study
Bacteroides sp. R6 species Decreases 👪 Source Study
Bacteroides sp. S-18 species Decreases 👪 Source Study
Bacteroides sp. Smarlab 3302398 species Decreases 👪 Source Study
Bacteroides sp. UW species Decreases 👪 Source Study
Bacteroides sp. WA1 species Decreases 👪 Source Study
Bacteroides sp. WH2 species Decreases 👪 Source Study
Bacteroides zoogleoformans species Decreases 👪 Source Study
Candidatus Bacteroides periocalifornicus McLean et al. 2015 species Decreases 👪 Source Study
CCUG 46149 species Decreases 👪 Source Study
CCUG 48363 species Decreases 👪 Source Study
CCUG 55896 species Decreases 👪 Source Study
CGMCC 1.15531 species Decreases 👪 Source Study
CGMCC 1.15532 species Decreases 👪 Source Study
CGMCC 1.15533 species Decreases 👪 Source Study
CGMCC 1.15534 species Decreases 👪 Source Study
CGMCC 1.15667 species Decreases 👪 Source Study
DSM 104980 species Decreases 👪 Source Study
DSM 18963 species Decreases 👪 Source Study
DSM 26920 species Decreases 👪 Source Study
environmental samples species Decreases 👪 Source Study
Holdemania massiliensis species Decreases 👪 Source Study
Holdemania sp. species Decreases 👪 Source Study
Roseburia sp. species Decreases 👪 Source Study
Roseburia sp. 1120 species Decreases 👪 Source Study
Roseburia sp. 11SE38 species Decreases 👪 Source Study
Roseburia sp. 499 species Decreases 👪 Source Study
Roseburia sp. DJF_VR77 species Decreases 👪 Source Study
Roseburia sp. MC_37 species Decreases 👪 Source Study
Streptococcus anginosus group species Decreases 👪 Source Study
Streptococcus bovis species Decreases 👪 Source Study
Streptococcus canis species Decreases 👪 Source Study
Streptococcus cristatus species Decreases 👪 Source Study
Streptococcus danieliae species Decreases 👪 Source Study
Streptococcus dentapri species Decreases 👪 Source Study
Streptococcus dentasini species Decreases 👪 Source Study
Streptococcus didelphis species Decreases 👪 Source Study
Streptococcus entericus species Decreases 👪 Source Study
Streptococcus G418 species Decreases 👪 Source Study
Streptococcus hyointestinalis species Decreases 👪 Source Study
Streptococcus hyovaginalis species Decreases 👪 Source Study
Streptococcus marimammalium species Decreases 👪 Source Study
Streptococcus massiliensis species Decreases 👪 Source Study
Streptococcus merionis species Decreases 👪 Source Study
Streptococcus milleri species Decreases 👪 Source Study
Streptococcus mitis species Decreases 👪 Source Study
Streptococcus oralis species Decreases 👪 Source Study
Streptococcus orisasini species Decreases 👪 Source Study
Streptococcus orisratti species Decreases 👪 Source Study
Streptococcus parauberis species Decreases 👪 Source Study
Streptococcus pharyngis species Decreases 👪 Source Study
Streptococcus phocae species Decreases 👪 Source Study
Streptococcus pluranimalium species Decreases 👪 Source Study
Streptococcus plurextorum species Decreases 👪 Source Study
Streptococcus porcorum species Decreases 👪 Source Study
Streptococcus pseudoporcinus species Decreases 👪 Source Study
Streptococcus rupicaprae species Decreases 👪 Source Study
Streptococcus sanguinis species Decreases 👪 Source Study
Streptococcus seminale species Decreases 👪 Source Study
Streptococcus sobrinus species Decreases 👪 Source Study
Streptococcus sp. 2_1_36FAA species Decreases 👪 Source Study
Streptococcus sp. 2011_Ileo_MS_A12 species Decreases 👪 Source Study
Streptococcus sp. 2011_Ileo_MS_C3 species Decreases 👪 Source Study
Streptococcus sp. 2011_Oral_MS_B3 species Decreases 👪 Source Study
Streptococcus sp. 2011_Oral_MS_D12 species Decreases 👪 Source Study
Streptococcus sp. 2011_Oral_MS_E1 species Decreases 👪 Source Study
Streptococcus sp. A12 species Decreases 👪 Source Study
Streptococcus sp. AS14 species Decreases 👪 Source Study
Streptococcus sp. BS35b species Decreases 👪 Source Study
Streptococcus sp. canine oral taxon 279 species Decreases 👪 Source Study
Streptococcus sp. F0441 species Decreases 👪 Source Study
Streptococcus sp. F0442 species Decreases 👪 Source Study
Streptococcus sp. FDAARGOS_192 species Decreases 👪 Source Study
Streptococcus sp. HPA1 species Decreases 👪 Source Study
Streptococcus sp. HPH0090 species Decreases 👪 Source Study
Streptococcus sp. HSISB1 species Decreases 👪 Source Study
Streptococcus sp. HSISM1 species Decreases 👪 Source Study
Streptococcus sp. HSISS1 species Decreases 👪 Source Study
Streptococcus sp. HSISS2 species Decreases 👪 Source Study
Streptococcus sp. I-G2 species Decreases 👪 Source Study
Streptococcus sp. JS71 species Decreases 👪 Source Study
Streptococcus sp. M143 species Decreases 👪 Source Study
Streptococcus sp. NPS 308 species Decreases 👪 Source Study
Streptococcus sp. oral taxon 064 species Decreases 👪 Source Study
Streptococcus sp. oral taxon 071 species Decreases 👪 Source Study
Streptococcus sp. oral taxon 431 species Decreases 👪 Source Study
Streptococcus sp. oral taxon G62 species Decreases 👪 Source Study
Streptococcus sp. oral taxon G63 species Decreases 👪 Source Study
Streptococcus sp. S16-08 species Decreases 👪 Source Study
Streptococcus sp. TM013 species Decreases 👪 Source Study
Streptococcus sp. Z15 species Decreases 👪 Source Study
Streptococcus suis species Decreases 👪 Source Study
Streptococcus troglodytae species Decreases 👪 Source Study
Streptococcus troglodytidis species Decreases 👪 Source Study
Streptococcus urinalis species Decreases 👪 Source Study
Streptococcus viridans species Decreases 👪 Source Study
[Haemophilus] ducreyi species Increases 👪 Source Study
Akkermansia glycaniphila species Increases 👪 Source Study
Akkermansia sp. species Increases 👪 Source Study
Blautia faecis species Increases 👪 Source Study
Blautia glucerasea species Increases 👪 Source Study
Blautia hansenii species Increases 👪 Source Study
Blautia hydrogenotrophica species Increases 👪 Source Study
Blautia luti species Increases 👪 Source Study
Blautia massiliensis species Increases 👪 Source Study
Blautia obeum species Increases 👪 Source Study
Blautia producta species Increases 👪 Source Study
Blautia schinkii species Increases 👪 Source Study
Blautia sp. species Increases 👪 Source Study
Blautia sp. KCTC 15426 species Increases 👪 Source Study
Blautia sp. MC_32 species Increases 👪 Source Study
Blautia sp. Ser5 species Increases 👪 Source Study
Blautia sp. Ser8 species Increases 👪 Source Study
Blautia sp. YHC-4 species Increases 👪 Source Study
Blautia stercoris species Increases 👪 Source Study
Blautia wexlerae species Increases 👪 Source Study
Haemophilus aegyptius species Increases 👪 Source Study
Haemophilus haemoglobinophilus species Increases 👪 Source Study
Haemophilus haemolyticus species Increases 👪 Source Study
Haemophilus parahaemolyticus species Increases 👪 Source Study
Haemophilus parainfluenzae species Increases 👪 Source Study
Haemophilus paraphrohaemolyticus species Increases 👪 Source Study
Haemophilus pittmaniae species Increases 👪 Source Study
Haemophilus quentini Olsen et al. 2005 species Increases 👪 Source Study
Haemophilus sp. species Increases 👪 Source Study
Haemophilus sp. 11p18 species Increases 👪 Source Study
Haemophilus sp. oral taxon 036 species Increases 👪 Source Study
Haemophilus sp. oral taxon 851 species Increases 👪 Source Study
Haemophilus sp. paraurethrae species Increases 👪 Source Study
Haemophilus sputorum species Increases 👪 Source Study
Akkermansia muciniphila species Increases 📓 Source Study
Blautia producta species Increases 📓 Source Study
Blautia wexlerae species Increases 📓 Source Study

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