We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.
This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.
Symptom | Impact | Predictor of Bacteria Shift |
---|---|---|
Comorbid-Mouth: Dry Mouth | Worsen | 2.74 |
Neuroendocrine: Feeling like you have a low temperature | Worsen | 2.74 |
Neurological: emotional overload | Worsen | 2.74 |
Neurological: fasciculations | Worsen | 2.74 |
Neurological: High degree of Empathy before onset | Worsen | 2.74 |
Neurological: Short-term memory issues | Worsen | 2.74 |
Neurological: Spatial instability and disorientation | Worsen | 2.74 |
Post-exertional malaise: General | Worsen | 2.74 |
Post-exertional malaise: Mentally tired after the slightest effort | Worsen | 2.74 |
Post-exertional malaise: Physically drained or sick after mild activity | Worsen | 2.74 |
Post-exertional malaise: Post-exertional malaise | Worsen | 2.74 |
Post-exertional malaise: Rapid cognitive fatigability, | Worsen | 2.74 |
Post-exertional malaise: Worsening of symptoms after mild mental activity | Worsen | 2.74 |
We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.
This is according to the microbiome shifts reported in studies. Clinical studies may show different results
Symptom | Impact | Predictor of Bacteria Shift |
---|---|---|
Allergies | Worsen | 2.74 |
Amyotrophic lateral sclerosis (ALS) Motor Neuron | Worsen | 2.74 |
Ankylosing spondylitis | Worsen | 2.5 |
Asthma | Worsen | 2.74 |
Atherosclerosis | Improves | -3.4 |
Autism | Worsen | 0 |
Brain Trauma | Improves | -2.74 |
Carcinoma | Improves | -2.41 |
Celiac Disease | Worsen | 0 |
Chronic Fatigue Syndrome | Worsen | 0 |
Chronic Kidney Disease | Improves | -2.41 |
Chronic urticaria (Hives) | Improves | -2.41 |
Colorectal Cancer | Improves | -3.13 |
Crohn's Disease | Improves | -2.61 |
Depression | Improves | -2.29 |
Epilepsy | Worsen | 2.54 |
Generalized anxiety disorder | Improves | -1.97 |
Graves' disease | Worsen | 2.74 |
High Blood Pressure | Improves | -2.54 |
Histamine Issues | Worsen | 2.28 |
IgA nephropathy (IgAN) | Improves | -3.31 |
Inflammatory Bowel Disease | Improves | -2.06 |
Irritable Bowel Syndrome | Improves | -3.4 |
Liver Cirrhosis | Improves | -3.08 |
ME/CFS with IBS | Worsen | 0 |
ME/CFS without IBS | Worsen | 0 |
Mood Disorders | Improves | -2.74 |
Obesity | Improves | -3.24 |
Osteoporosis | Improves | -2.41 |
Parkinson's Disease | Improves | -2.74 |
Psoriasis | Worsen | 2.54 |
Rheumatoid arthritis | Improves | -2.52 |
rheumatoid arthritis (RA),Spondyloarthritis (SpA) | Worsen | 2.54 |
Schizophrenia | Worsen | 2.74 |
Sjögren syndrome | Improves | -2.41 |
Small Intestinal Bacterial Overgrowth (SIBO) | Worsen | 2.54 |
Stress / posttraumatic stress disorder | Worsen | 1.95 |
Type 2 Diabetes | Improves | -3.52 |
Ulcerative colitis | Worsen | 2.54 |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.