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Diagnostic Imaging: Meglumine is commonly used as a contrast agent in diagnostic imaging procedures such as X-rays, CT scans, and MRI scans. It enhances the visibility of certain tissues and organs, allowing healthcare providers to obtain clearer images for the diagnosis and evaluation of various medical conditions, including injuries, tumors, and other abnormalities.
Treatment of Visceral Leishmaniasis: Glucantime, a formulation of meglumine antimoniate, is used for the treatment of visceral leishmaniasis, a parasitic infection caused by Leishmania species. Glucantime works by inhibiting the growth and replication of the parasite, thereby helping to eliminate the infection. It is administered intravenously and may be used in combination with other antileishmanial medications.
Metabolic Disorders: Meglumine has been investigated for its potential therapeutic effects in metabolic disorders such as diabetes mellitus. Some studies suggest that meglumine may have insulin-sensitizing properties and could potentially improve glucose metabolism. However, further research is needed to fully understand its role in the management of metabolic conditions.
Radioprotective Properties: There is some evidence to suggest that meglumine may possess radioprotective properties, meaning it could help protect cells and tissues from the damaging effects of ionizing radiation. This property has been studied in the context of radiation therapy for cancer and in radiation exposure scenarios, but its clinical significance and applications require further investigation.
Anti-inflammatory Effects: Meglumine has been investigated for its potential anti-inflammatory effects in various experimental models. It may modulate immune responses and inflammatory processes, which could have implications for the treatment of inflammatory conditions such as arthritis, inflammatory bowel disease, and autoimmune disorders. However, more research is needed to elucidate its mechanisms of action and therapeutic potential in these contexts.
Antiviral Activity: Cycloferon, a formulation containing meglumine acridone acetate, has been studied for its potential antiviral activity against a range of viruses, including herpes simplex virus, human immunodeficiency virus (HIV), and hepatitis viruses. It is believed to exert its antiviral effects by stimulating the immune system and enhancing the body's natural defense mechanisms. However, further clinical studies are needed to confirm its efficacy and safety for the treatment of viral infections.
Antioxidant Properties: Meglumine may possess antioxidant properties, which could help neutralize harmful free radicals and reduce oxidative stress in the body. This antioxidant activity has potential implications for various health conditions associated with oxidative damage, including neurodegenerative diseases, cardiovascular disorders, and aging-related processes.
Rank | Probiotic | Impact |
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We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
Taxonomy | Rank | Effect | Citations | Notation |
---|---|---|---|---|
unclassified Robinsoniella | no rank | Decreases | ⚗️ Source Study | |
unclassified Fusobacterium | no rank | Decreases | ⚗️ Source Study | |
unclassified Negativicoccus | no rank | Decreases | ⚗️ Source Study | |
Eggerthellales | order | Decreases | ⚗️ Source Study | |
Anaerofustis stercorihominis | species | Decreases | ⚗️ Source Study | |
Asaccharospora irregularis | species | Decreases | ⚗️ Source Study | |
Negativicoccus sp. S5-A15 | species | Decreases | ⚗️ Source Study | |
Paraprevotella clara | species | Decreases | ⚗️ Source Study | |
Slackia sp. NATTS | species | Decreases | ⚗️ Source Study | |
Pseudoflavonifractor capillosus | species | Decreases | ⚗️ Source Study | |
[Collinsella] massiliensis | species | Decreases | ⚗️ Source Study | |
Parvibacter caecicola | species | Decreases | ⚗️ Source Study | |
Coriobacterineae | suborder | Decreases | ⚗️ Source Study | |
Chlamydiae/Verrucomicrobia group | superphylum | Decreases | ⚗️ Source Study |
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
---|---|---|---|
Chronic Fatigue Syndrome | 0.1 | 0.1 | |
Depression | 0.3 | 0.3 | |
ME/CFS without IBS | 0.1 | 0.1 | |
Mood Disorders | 0.3 | 0.3 |
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