265 Samples Reporting

Symptoms when uBiome was taken

Only symptoms associated with at least one abnormal metabolite are shown. This is based on Gut bacteria only.

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Neuroendocrine Manifestations: worsening of symptoms with stress.

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Based on self-reporting

• Neuroendocrine Manifestations: worsening of symptoms with stress. : 52
• General: Fatigue : 47
• Neurological: Impairment of concentration : 45
• Neurological: Executive Decision Making (Difficulty making) : 38
• Neurocognitive: Slowness of thought : 38
• Sleep: Unrefreshed sleep : 37
• Neurological-Audio: hypersensitivity to noise : 37
• Immune Manifestations: general malaise : 36
• Immune Manifestations: Bloating : 36
• Neurocognitive: Absent-mindedness or forgetfulness : 36
• Neuroendocrine Manifestations: intolerance of extremes of heat and cold : 35
• General: Myalgia (pain) : 32
• General: Headaches : 32
• Autonomic Manifestations: irritable bowel syndrome : 31
• Neurological: Cognitive/Sensory Overload : 31
• Neurocognitive: Problems remembering things : 31
• Neurocognitive: Difficulty paying attention for a long period of time : 30
• Neurocognitive: Can only focus on one thing at a time : 30
• Neurological: Word-finding problems : 30
• Post-exertional malaise: Inappropriate loss of physical and mental stamina, : 29
• Comorbid-Mouth: Bruxism - Jaw cleanching / Teeth grinding : 29
• Neurological-Audio: Tinnitus (ringing in ear) : 28
• Immune Manifestations: Constipation : 28
• Neurological-Vision: photophobia (Light Sensitivity) : 28
• Neuroendocrine Manifestations: cold extremities : 28
• Neurocognitive: Brain Fog : 28
• Neurological-Vision: inability to focus eye/vision : 27
• Neurological: Difficulty reading : 27
• Neuroendocrine Manifestations: sweating episodes : 26
• Neurocognitive: Unable to focus vision and/or attention : 26
• Neurological: Short-term memory issues : 25
• Neurological: Difficulty processing information (Understanding) : 25
• Neuroendocrine Manifestations: subnormal body temperature : 25
• Immune Manifestations: Alcohol Intolerant : 25
• Neuroendocrine Manifestations: Rapid muscular fatiguability : 25
• Gender: Female : 25
• Sleep: Problems staying asleep : 25
• Sleep: Daytime drowsiness : 24
• Neurological: emotional overload : 24
• Neuroendocrine Manifestations: Muscle weakness : 24
• Neurological-Sleep: Insomnia : 24
• Immune: Sensitivity to smell/food/medication/chemicals : 24
• Comorbid: Histamine or Mast Cell issues : 23
• Immune Manifestations: Abdominal Pain : 22
• Post-exertional malaise: General : 22
• Joint: Stiffness and swelling : 22
• Official Diagnosis: Irritable Bowel Syndrome : 21
• Post-exertional malaise: Rapid cognitive fatigability, : 21
• Neurological-Sleep: Chaotic diurnal sleep rhythms (Erratic Sleep) : 21
• Comorbid-Mouth: TMJ / Dysfunction of the temporomandibular joint syndrome : 21
• Sleep: Waking up early in the morning (e.g. 3 AM) : 20
• Infection: Epstein-Barr virus : 20
• Post-exertional malaise: Post-exertional malaise : 20
• Post-exertional malaise: Difficulty reading after mild physical or mental activity : 19
• General: Depression : 19
• Immune Manifestations: medication sensitivities. : 19
• Immune Manifestations: tender lymph nodes : 19
• Neurological-Sleep: Night Sweats : 19
• Neurological-Vision: Blurred Vision : 19
• Neurological-Sleep: Inability for deep (delta) sleep : 18
• Onset: 2010-2020 : 18
• Gender: Male : 18
• Immune Manifestations: recurrent flu-like symptoms : 18
• Onset: Gradual : 18
• Comorbid: Hypothyroidism : 18
• Neuroendocrine: Feeling hot or cold for no reason : 18
• Neuroendocrine: Alcohol intolerance : 18
• Neuroendocrine: Cold limbs (e.g. arms, legs hands) : 17
• Post-exertional malaise: Physically drained or sick after mild activity : 17
• Post-exertional malaise: Muscle fatigue after mild physical activity : 17
• Post-exertional malaise: Worsening of symptoms after mild physical activity : 17
• Immune Manifestations: new food sensitivities : 17
• Neuroendocrine Manifestations: Dry Eye (Sicca or Sjogren Syndrome) : 17
• Neurological: Seasonal Affective Disorder (SAD) : 16
• Immune Manifestations: Diarrhea : 16
• Age: 60-70 : 16
• Post-exertional malaise: Physically tired after minimum exercise : 16
• Pain: Joint pain : 16
• Neurocognitive: Difficulty expressing thoughts : 16
• Neurocognitive: Difficulty understanding things : 16
• Pain: Sensitivity to pain : 15
• Age: 30-40 : 15
• Immune Manifestations: Hair loss : 15
• Neuroendocrine Manifestations: abnormal appetite : 15
• Autonomic Manifestations: nausea : 15
• Post-exertional malaise: Rapid muscular fatigability, : 15
• Autonomic Manifestations: urinary frequency dysfunction : 15
• Autonomic Manifestations: Postural orthostatic tachycardia syndrome (POTS) : 14
• Neuroendocrine Manifestations: marked weight change : 14
• Infection: Human Herpesvirus 6 (HHV6) : 14
• Neurological: Joint hypermobility : 14
• Onset: 2000-2010 : 14
• Immune: Recurrent Sore throat : 14
• Autonomic: Inability to tolerate an upright position : 14
• Immune Manifestations: Inflammation of skin, eyes or joints : 14
• Joint: Tenderness : 13
• Post-exertional malaise: Next-day soreness after everyday activities : 13
• Neurocognitive: Feeling disoriented : 13
• Immune: Flu-like symptoms : 13
• Autonomic: Shortness of breath : 13
• Blood Type: O Positive : 13
• Comorbid: High Anxiety : 13
• Pain: Pain or aching in muscles : 13
• Comorbid-Mouth: Dry Mouth : 13
• Neurological-Sleep: Vivid Dreams/Nightmares : 13
• Neurological: Confusion : 13
• Neurological: Spatial instability and disorientation : 13
• Autonomic Manifestations: light-headedness : 12
• Neurological: Dysautonomia : 12
• Comorbid: Constipation and Explosions (not diarrohea) : 12
• Official Diagnosis: Allergic Rhinitis (Hay Fever) : 12
• Comorbid: Snoring (NOT Sleep Apnea : 12
• Official Diagnosis: Mast Cell Dysfunction : 12
• Autonomic: Nausea : 12
• Post-exertional malaise: Worsening of symptoms after mild mental activity : 12
• Immune Manifestations: Mucus in the stool : 12
• Official Diagnosis: Chronic Fatigue Syndrome : 11
• Other: Sensitivity to mold : 11
• Autonomic: Irregular heartbeats : 11
• Immune: Tender / sore lymph nodes : 11
• Neuroendocrine: Temperature fluctuations throughout the day : 11
• Neuroendocrine: Lost or gained weight without trying : 11
• Comorbid: Multiple Chemical Sensitivity : 11
• Comorbid: Fibromyalgia : 11
• Neuroendocrine Manifestations: recurrent feelings of feverishness : 11
• Comorbid: Mold Sensitivity / Exposure : 11
• Onset: less than 16 years since onset : 10
• Sleep: Problems falling asleep : 10
• Comorbid: Small intestinal bacterial overgrowth (SIBO) : 10
• Neuroendocrine Manifestations: loss of adaptability : 10
• Neurological: Slowed speech : 10
• Autonomic Manifestations: palpitations : 10
• Autonomic Manifestations: cardiac arrhythmias : 10
• Autonomic Manifestations: Orthostatic intolerance : 10
• Neurological: Disorientation : 10
• Pain: Aching of the eyes or behind the eyes : 10
• Neuroendocrine: Chills or shivers : 10
• Autonomic: Heart rate increase after standing : 10
• Autism: Official Diagnosis : 10
• Post-exertional malaise: Mentally tired after the slightest effort : 10
• Autonomic: Dizziness or fainting : 9
• General: Sinus issues with headaches : 9
• DePaul University Fatigue Questionnaire : Unrefreshing Sleep, that is waking up feeling tired : 9
• Autonomic Manifestations: exertional dyspnea : 9
• Neuroendocrine Manifestations: Excessive adrenaline : 9
• Neuroendocrine Manifestations: Paraesthesia (tingling burning of skin) : 9
• Neurological: High degree of Empathy before onset : 9
• Asymptomatic: No Health Issues : 8
• Age: 50-60 : 8
• Immune: Viral infections with prolonged recovery periods : 8
• Neuroendocrine: Feeling like you have a high temperature : 8
• Neuroendocrine: Feeling like you have a low temperature : 8
• Pain: Myofascial pain : 8
• Pain: Eye pain : 7
• Pain: Chest pain : 7
• Neuroendocrine: Sweating hands : 7
• Other: Sensitivity to vibrations : 7
• Sleep: Need to nap daily : 7
• Comorbid: Restless Leg : 7
• Asymptomatic: Live in house with person with probable microbiome dysfunction : 7
• Autonomic Manifestations: Cortisol disorders or irregularity : 7
• Neuroendocrine Manifestations: Air Hunger : 7
• Neuroendocrine Manifestations: Neuralgia : 7
• Neurological: Neuropathy : 7
• Neurological: fasciculations : 7
• Neuroendocrine Manifestations: marked diurnal fluctuation : 6
• Comorbid: Electromagnetic Sensitivity (EMF) : 6
• Neurological-Vision: Acquired or exertional dyslexia : 6
• Neurological-Vision: Impaired Depth Perceptions : 6
• Infection: Mycoplasma : 6
• Neurological-Sleep: Sleep Apnea : 6
• Immune Manifestations: Genitorinary / Nocturia - Urinary issues : 6
• Comorbid: Inflammatory bowel disease : 6
• Asymptomatic: Minor Health Issues (a few symptoms only) : 6
• Autonomic: Blurred or tunnel vision after standing : 6
• Official Diagnosis: Attention deficit hyperactivity disorder (ADHD) : 6
• Official Diagnosis: Autoimmune Disease : 6
• Comorbid-Mouth: Mouth Sores : 6
• Joint: Sudden and severe episodes of pain : 5
• Neuroendocrine: Lack of appetite : 5
• DePaul University Fatigue Questionnaire : Impaired Memory & concentration : 5
• Immune Manifestations: Inflammation (General) : 5
• Comorbid-Mouth: Gingivits / Gum Disease : 5
• Age: 20-30 : 5
• Onset: over 31 years since onset : 5
• Immune Manifestations: Thick blood / Hypercoagulation : 5
• Onset: Sudden : 5
• Infection: Lyme : 4
• Neurological: Ataxia (lack of volunatary muscle control) : 4
• Neurological-Sleep: Prolonged Sleep : 4
• Neurological: Myoclonic jerks or seizures : 4
• Infection: Parasite - Other : 4
• Onset: 1990-2000 : 4
• Official Diagnosis: Fibromyalgia : 4
• DePaul University Fatigue Questionnaire : Fatigue : 4
• Autonomic Manifestations: Chemical Smelling Urine (atypical) : 4
• Joint: Redness : 4
• Official Diagnosis: Depression : 3
• Official Diagnosis: High Blood Pressure (Hypertension) : 3
• Official Diagnosis: Mood Disorders : 3
• Autonomic: Graying or blacking out after standing : 3
• Autonomic: Ocassional Tachycardia (Rapid heart beat) : 3
• Comorbid: Methylation issues (MTHFR) : 3
• General: Heavy feeling in arms and legs : 3
• Immune Manifestations: hives : 3
• Onset: 1980-1990 : 3
• Age: 40-50 : 3
• Comorbid-Mouth: Periradicular periodontitis inflammatory / chronic lesion around roots of teeth : 3
• Immune Manifestations: High Altitude Intolerance : 3
• Onset: less than 32 years since onset : 3
• Onset: less than 02 years since onset : 3
• Onset: less than 04 years since onset : 3
• Autonomic Manifestations: bladder dysfunction : 3
• Autonomic Manifestations: extreme pallor : 2
• Autonomic Manifestations: Neurally mediated hypotension (NMH) : 2
• Onset: less than 08 years since onset : 2
• Infection: Parvovirus : 2
• Infection: Parasites - Giardia : 2
• Comorbid: Crohn's Disease : 2
• Age: 10-20 : 2
• Infection: Coxsackie : 2
• Sleep: Sleeping all day and staying awake all night : 2
• Neuroendocrine Manifestations: Painful menstrual periods : 2
• Autonomic: Vasovagal syncope (easy fainting) : 2
• Comorbid: Carbohydrate intolerance : 2
• Comorbid-Mouth: Ulcers (mouth) : 2
• Comorbid: Raynaud’s syndrome (Skin discoloration) : 2
• Blood Type: A Positive : 2
• Immune: Chronic Sinusitis : 2
• Comorbid: Migraine : 2
• Comorbid: Mood Swings : 2
• Official Diagnosis: Rheumatoid arthritis : 2
• Official Diagnosis: Metabolic Syndrome : 2
• Official Diagnosis: Inflammatory Bowel Disease (IBD) : 2
• Official Diagnosis: Crohn's Disease : 2
• Comorbid: Malodor : 2
• Official Diagnosis: Gout : 1
• Immune Manifestations: vomiting : 1
• Comorbid: Constipation and Diarrohea (not explosions) : 1
• Official Diagnosis: Gastroesophageal reflux disease (GERD) : 1
• Autonomic Manifestations: Enuresis (involuntary urination) : 1
• Blood Type: B Positive : 1
• Comorbid: Cushing Syndrome : 1
• Comorbid: Cancer : 1
• Neuroendocrine Manifestations: Laboured breathing : 1
• Autonomic Manifestations: delayed postural hypotension : 1
• Infection: Varicella Zoster Virus : 1
• Neurological-Sleep: Sleep Reversal : 1

Metabolites

Name	Low	High	Average	Count
Amino acid metabolism: Alanine, aspartate and glutamate metabolism	8	5	0.905	52
Amino acid metabolism: Arginine and proline metabolism	7	8	0.8903846153846153	52
Amino acid metabolism: beta-Alanine metabolism	16	4	0.869326923076923	52
Amino acid metabolism: Cyanoamino acid metabolism	14	15	0.8949038461538462	52
Amino acid metabolism: Cysteine and methionine metabolism	13	3	0.8621153846153846	52
Amino acid metabolism: D-Alanine metabolism	21	1	0.8002884615384614	52
Amino acid metabolism: D-Arginine and D-ornithine metabolism	41	8	0.6289423076923075	52
Amino acid metabolism: D-Glutamine and D-glutamate metabolism:	10	7	0.873173076923077	52
Amino acid metabolism: Glutathione metabolism	18	7	0.8685576923076923	52
Amino acid metabolism: Glycine, serine and threonine metabolism	11	1	0.864230769230769	52
Amino acid metabolism: Histidine metabolism	9	7	0.8741346153846153	52
Amino acid metabolism: Lysine biosynthesis	11	4	0.8653846153846154	52
Amino acid metabolism: Lysine degradation	19	15	0.901153846153846	52
Amino acid metabolism: Phenylalanine metabolism	9	17	0.9178846153846152	52
Amino acid metabolism: Phenylalanine, tyrosine and tryptophan biosynthesis	14	1	0.8601923076923075	52
Amino acid metabolism: Phosphonate and phosphinate metabolism	10	28	0.9914423076923072	52
Amino acid metabolism: Selenocompound metabolism	10	6	0.8651923076923077	52
Amino acid metabolism: Taurine and hypotaurine metabolism	13	13	0.8886538461538458	52
Amino acid metabolism: Tryptophan metabolism	18	19	0.9299038461538458	52
Amino acid metabolism: Tyrosine metabolism	16	3	0.8512499999999998	52
Amino acid metabolism: Valine, leucine and isoleucine biosynthesis	10	5	0.8654807692307693	52
Amino acid metabolism: Valine, leucine and isoleucine degradation	14	17	0.9245192307692309	52
Bacterial Abilities: Bacterial chemotaxis	29	9	0.8176923076923079	52
Bacterial Abilities: Bacterial motility proteins	30	13	0.803173076923077	52
Bacterial Abilities: Bacterial secretion system	15	15	0.9034615384615385	52
Bacterial Abilities: beta-Lactam resistance	18	17	0.8978846153846152	52
Bacterial Abilities: Cell division	13	9	0.9024038461538463	52
Bacterial Abilities: Cell motility and secretion	13	25	1.0104807692307693	52
Bacterial Abilities: Flagellar assembly	32	13	0.7690384615384616	52
Bacterial Abilities: Lysosome	12	30	1.0791346153846155	52
Bacterial Abilities: Phagosome	21	19	3.8959615384615387	52
Bacterial Abilities: Sporulation	29	10	0.8288461538461538	52
Carbohydrate metabolism: Amino sugar and nucleotide sugar metabolism	12	7	0.8976923076923077	52
Carbohydrate metabolism: Ascorbate and aldarate metabolism	13	20	0.9472115384615384	52
Carbohydrate metabolism: Butanoate metabolism	8	14	0.8770192307692306	52
Carbohydrate metabolism: C5-Branched dibasic acid metabolism	9	6	0.8939423076923079	52
Carbohydrate metabolism: Citrate cycle (TCA cycle)	11	25	0.9797115384615385	52
Carbohydrate metabolism: Fructose and mannose metabolism	17	8	0.8907692307692309	52
Carbohydrate metabolism: Galactose metabolism	14	12	0.9062500000000001	52
Carbohydrate metabolism: Glycolysis / Gluconeogenesis	12	3	0.8846153846153846	52
Carbohydrate metabolism: Glyoxylate and dicarboxylate metabolism	10	8	0.8954807692307694	52
Carbohydrate metabolism: Inositol phosphate metabolism	9	17	0.9579807692307694	52
Carbohydrate metabolism: Pentose and glucuronate interconversions	9	17	1.0312499999999998	52
Carbohydrate metabolism: Pentose phosphate pathway	9	8	0.9914423076923077	52
Carbohydrate metabolism: Propanoate metabolism	10	10	0.8660576923076921	52
Carbohydrate metabolism: Pyruvate metabolism	7	6	0.8880769230769231	52
Carbohydrate metabolism: Starch and sucrose metabolism	15	5	0.8905769230769228	52
Lipid metabolism: alpha-Linolenic acid metabolism	33	14	0.8612499999999998	52
Lipid metabolism: Arachidonic acid metabolism	36	8	0.6954807692307694	52
Lipid metabolism: Biosynthesis of unsaturated fatty acids	24	11	0.8802884615384615	52
Lipid metabolism: Ether lipid metabolism	31	14	0.7855769230769231	52
Lipid metabolism: Fatty acid biosynthesis	10	6	0.8836538461538462	52
Lipid metabolism: Glycerolipid metabolism	16	6	0.8833653846153846	52
Lipid metabolism: Glycerophospholipid metabolism	12	2	0.8821153846153847	52
Lipid metabolism: Linoleic acid metabolism	12	19	0.9238461538461539	52
Lipid metabolism: Sphingolipid metabolism	15	20	0.9564423076923075	52
Lipid metabolism: Steroid biosynthesis	29	19	1.7508653846153845	52
Lipid metabolism: Steroid hormone biosynthesis	18	29	1.1475961538461537	52
Lipid metabolism: Synthesis and degradation of ketone bodies	28	11	0.7674038461538462	52
other: ß-galactosidase (estrogen related)	17	0	-0.5294117647058824	17
other: ß-glucuronidase (estrogen related)	17	0	-0.5294117647058824	17
Secondary metabolite biosynthesis: Betalain biosynthesis	24	14	1.1971153846153846	52
Secondary metabolite biosynthesis: Butirosin and neomycin biosynthesis	16	12	0.8194230769230769	52
Secondary metabolite biosynthesis: Caffeine metabolism	30	17	1.47625	52
Secondary metabolite biosynthesis: Flavone and flavonol biosynthesis	22	21	1.1002884615384618	52
Secondary metabolite biosynthesis: Flavonoid biosynthesis	24	25	1.171153846153846	52
Secondary metabolite biosynthesis: Indole alkaloid biosynthesis	23	16	1.3104807692307694	52
Secondary metabolite biosynthesis: Isoquinoline alkaloid biosynthesis	16	11	0.8609615384615383	52
Secondary metabolite biosynthesis: Novobiocin biosynthesis	9	6	0.8512500000000002	52
Secondary metabolite biosynthesis: Penicillin and cephalosporin biosynthesis	16	32	1.0612499999999998	52
Secondary metabolite biosynthesis: Phenylpropanoid biosynthesis	19	20	0.893846153846154	52
Secondary metabolite biosynthesis: Stilbenoid, diarylheptanoid and gingerol biosynthesis	25	26	1.5289423076923074	52
Secondary metabolite biosynthesis: Streptomycin biosynthesis	11	14	0.8723076923076925	52
Secondary metabolite biosynthesis: Tropane, piperidine and pyridine alkaloid biosynthesis	15	7	0.8093269230769228	52
Secondary metabolite degradation: Aminobenzoate degradation	18	15	0.8849038461538462	52
Secondary metabolite degradation: Atrazine degradation	28	19	1.02	52
Secondary metabolite degradation: Benzoate degradation	23	5	0.785673076923077	52
Secondary metabolite degradation: Bisphenol degradation	13	17	0.8524038461538461	52
Secondary metabolite degradation: Caprolactam degradation	28	20	0.9534615384615386	52
Secondary metabolite degradation: Chloroalkane and chloroalkene degradation	14	15	0.8785576923076922	52
Secondary metabolite degradation: Chlorocyclohexane and chlorobenzene degradation	22	21	0.9653846153846153	52
Secondary metabolite degradation: Dioxin degradation	31	6	0.7162499999999999	52
Secondary metabolite degradation: Drug metabolism - cytochrome P450	24	20	0.9795192307692306	52
Secondary metabolite degradation: Drug metabolism - other enzymes	15	4	0.79875	52
Secondary metabolite degradation: Ethylbenzene degradation	26	14	0.8141346153846154	52
Secondary metabolite degradation: Fluorobenzoate degradation	34	18	1.3514423076923083	52
Secondary metabolite degradation: Metabolism of xenobiotics by cytochrome P450	25	18	0.9275961538461537	52
Secondary metabolite degradation: Naphthalene degradation	21	9	0.8308653846153846	52
Secondary metabolite degradation: Nitrotoluene degradation	17	16	0.8958653846153847	52
Secondary metabolite degradation: Polycyclic aromatic hydrocarbon degradation	19	2	0.8130769230769229	52
Secondary metabolite degradation: Styrene degradation	24	17	0.9179807692307695	52
Secondary metabolite degradation: Toluene degradation	14	31	1.0614423076923074	52
Secondary metabolite degradation: Xylene degradation	31	7	0.7203846153846152	52
Vitamin metabolism: Biotin metabolism	15	12	0.8795192307692308	52
Vitamin metabolism: Folate biosynthesis	14	5	0.8723076923076923	52
Vitamin metabolism: Lipoic acid metabolism	17	28	1.1414423076923077	52
Vitamin metabolism: Nicotinate and nicotinamide metabolism	16	1	0.8193269230769228	52
Vitamin metabolism: One carbon pool by folate	14	1	0.8213461538461538	52
Vitamin metabolism: Pantothenate and CoA biosynthesis	13	3	0.8586538461538462	52
Vitamin metabolism: Porphyrin and chlorophyll metabolism	15	11	0.8738461538461539	52
Vitamin metabolism: Retinol metabolism	22	16	0.9167307692307691	52
Vitamin metabolism: Riboflavin metabolism	18	3	0.8481730769230769	52
Vitamin metabolism: Thiamine metabolism	14	2	0.8585576923076922	52
Vitamin metabolism: Ubiquinone and other terpenoid-quinone biosynthesis:	19	25	0.9671153846153845	52
Vitamin metabolism: Vitamin B6 metabolism	14	4	0.8580769230769232	52

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