Porphyromonas Details: NCBI 836, gram-negative or unknown [genus]

| Oribaculum| Oribaculum Moore and Moore 1994| Porphyromonas| Porphyromonas Shah and Collins 1988 emend. Kawamura et al. 2015| Porphyromonas Shah and Collins 1988 emend. Wagener et al. 2014| Porphyromonas Shah and Collins 1988 emend. Willems and Collins 1995

1. Oral Health:

   • Some species of Porphyromonas are part of the normal oral microbiota in humans. However, they are often associated with periodontal diseases, including gingivitis and periodontitis. Porphyromonas gingivalis, in particular, is known for its role in periodontal disease.

2. Periodontal Diseases:

   • Porphyromonas gingivalis is considered a major pathogen in periodontal diseases. It can contribute to the inflammation of the gums (gingivitis) and the destruction of the supporting structures of the teeth (periodontitis). The bacterium can form biofilms on tooth surfaces and trigger an immune response that leads to tissue damage.

3. Systemic Health Implications:

   • Some research suggests that the presence of Porphyromonas gingivalis in the oral cavity may be associated with systemic health issues. There have been studies exploring potential links between periodontal diseases and conditions such as cardiovascular disease, diabetes, and adverse pregnancy outcomes. However, the nature of these associations is complex and continues to be an area of research.

4. Immune System Interactions:

   • Porphyromonas species, particularly Porphyromonas gingivalis, are capable of evading the host immune response and modulating the inflammatory environment. This ability to manipulate the immune system contributes to the chronicity of periodontal infections.

5. Research and Therapeutic Approaches:

   • Understanding the virulence factors and pathogenic mechanisms of Porphyromonas species is essential for developing strategies to prevent and treat periodontal diseases. Research is ongoing to explore potential therapeutic approaches, including vaccines and targeted antimicrobial agents.

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Other Sources for more information:

• Immune Epitope Database
• The NCBI taxonomy database
• UniProt
• Immune Epitope Taxonomy Database (IEDB)
• AI Engines For more Details: Perplexity  Kagi Labs  You 

More Information

Statistics

NCBI

Data Punk

End Products Produced

Lab Reporting

Different labs use different software to read the sample. See this post for more details.
One lab may say you have none, another may say you have a lot! - This may be solely due to the software they are using to estimate.
We deem lab specific values using values from the KM method for each specific lab to be the most reliable.

Desired Levels Suggestions for Porphyromonas

• Frequency - how often do samples show this bacteria
• UD - An alternative statistical algorithm (which factors in the frequency)
• Kaltoft-Moldrup Heuristic Using uploaded data
• Lab Low and High are calculated using the formula that most labs use: Mean - 2 Standard Deviation to Mean + 2 Standard Deviation

These are values that are computed from lab specific samples (Patent Pending)

Lab	Frequency	UD-Low	UD-High	KM Low	KM High	Lab Low	Lab High	Mean	Median	Standard Deviation	Box Plot Low	Box Plot High	KM Percentile Low	KM Percentile High
Other Labs	3.84	0	0	10	423718	0	191009	25273.3	397	84558.9	0	5903	0 %ile	100 %ile
biomesight	77.07	0	160	30	480	0	10925	1063.9	90	5031	0	430	9.1 %ile	90.7 %ile
thorne	100			33	110470	0	49473	7860.2	739	21231.1	0	9499	0 %ile	100 %ile
thryve	81.23	0	231	30	511	0	20695	1512.9	106	9786.6	0	526	11.8 %ile	90.3 %ile
ubiome	41.57	0	109	15	3065	0	29510	3879.1	349	13076.9	0	3413	0 %ile	92 %ile

External Reference Ranges for Porphyromonas

Porphyromonas (NCBI 836) per million

Source of Ranges	Low Boundary	High Boundary	Low Boundary %age	High Boundary %age
Lab Teletest	0	500	0	0.05
Thorne (20/80%ile)	64.24	142.06	0.0064	0.0142

Statistic by Lab Source for Porphyromonas

These desired values are reported from the lab reports

Lab	Frequency Seen	Average	Standard Deviation	Sample Count	Lab Samples
AmericanGut	60 %	0.027 %	0.032 %	9.0	15
BiomeSight	82.883 %	0.112 %	0.561 %	2455.0	2962
BiomeSightRdp	51.613 %	0.059 %	0.096 %	16.0	31
CerbaLab	100 %	0.011 %	0.006 %	3.0	3
CosmosId	78.125 %	0.425 %	0.41 %	25.0	32
custom	18.033 %	0.009 %	0.005 %	11.0	61
es-xenogene	79.31 %	0.01 %	0.011 %	23.0	29
Medivere	85.714 %	0.006 %	0.004 %	6.0	7
Microba	7.143 %	0.139 %	0.141 %	2.0	28
Microba1	100 %	0.25 %	%	1.0	1
SequentiaBiotech	41.667 %	13.824 %	16.539 %	15.0	36
Thorne	85.149 %	0.357 %	1.327 %	86.0	101
Thryve	80.634 %	0.151 %	0.943 %	1120.0	1389
uBiome	41.414 %	0.388 %	1.308 %	328.0	792

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Data Contradictions — Limits of Certainity

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General Substance	Specific Substance	Effect
Amino Acid and similar	acetic acid	1 Studies recorded. The consensus is Increases📓, Click for details.
Amino Acid and similar	Alpha-Ketoglutarate	1 Studies recorded. The consensus is Increases📓, Click for details.
Amino Acid and similar	Conjugated Linoleic Acid	1 Studies recorded. The consensus is Increases📓, Click for details.
Antibiotics, Antivirals etc	amoxicillin (antibiotic)s[CFS]	1 Studies recorded. The consensus is Increases📓, Click for details.
Antibiotics, Antivirals etc	ceftriaxone (antibiotic)s	1 Studies recorded. The consensus is Increases📓, Click for details.
Antibiotics, Antivirals etc	clindamycin (antibiotic)s[CFS]	1 Studies recorded. The consensus is Decreases📓, Click for details.
Antibiotics, Antivirals etc	doxycycline (antibiotic)s[CFS]	2 Studies recorded. The consensus is Decreases👶👪, Click for details.
Antibiotics, Antivirals etc	fluoroquinolone (antibiotic)s	1 Studies recorded. The consensus is Decreases👶, Click for details.
Antibiotics, Antivirals etc	penicillin-moxalactam (antibiotic)s	1 Studies recorded. The consensus is Decreases📓, Click for details.
Common Supplements	Bromelain	1 Studies recorded. The consensus is Decreases👪, Click for details.
Diet Style	animal-based diet	1 Studies recorded. The consensus is Increases📓, Click for details.
Diet Style	gluten-free diet	1 Studies recorded. The consensus is Increases👶, Click for details.
Diet Style	high-fat diets	1 Studies recorded. The consensus is Decreases📓, Click for details.
Diet Style	ketogenic diet	1 Studies recorded. The consensus is Increases📓, Click for details.
Diet Style	mediterranean diet	1 Studies recorded. The consensus is Increases📓, Click for details.
Diet Style	vegetable/fruit juice-based diets	1 Studies recorded. The consensus is Increases📓, Click for details.
Drug or "Non-drug"	acetylsalicylic acid,aspirin	1 Studies recorded. The consensus is Increases📓, Click for details.
Drug or "Non-drug"	chlorhexidine	1 Studies recorded. The consensus is Decreases👪, Click for details.
Drug or "Non-drug"	epinephrine	1 Studies recorded. The consensus is Increases📓, Click for details.
Drug or "Non-drug"	Methylene blue	1 Studies recorded. The consensus is Decreases👪, Click for details.
flavonoids, polyphenols etc	grape polyphenols	1 Studies recorded. The consensus is Decreases👶, Click for details.
flavonoids, polyphenols etc	Guaiacol (polyphenol)	1 Studies recorded. The consensus is Increases📓, Click for details.
flavonoids, polyphenols etc	resveratrol (grape seed/polyphenols/red wine)	1 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings)	barley	3 Studies recorded. The consensus is Decreases👶📓, Click for details.
Food (excluding seasonings)	blackcurrant	1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings)	brown algae	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	Far infrared Sauna	1 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings)	fat	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	fruit/legume fibre	1 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	high red meat	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	ku ding cha tea	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	pea (fiber, protein)	2 Studies recorded. The consensus is Increases👶📓, Click for details.
Food (excluding seasonings)	pectin	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	pomegranate	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	safflower oil	1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings)	tea	1 Studies recorded. The consensus is Decreases📓, Click for details.
Food (excluding seasonings)	Umeboshi (Japanese Apricot or Prunus mume )	1 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings)	whole-grain barley	1 Studies recorded. The consensus is Decreases👶, Click for details.
Herb or Spice	berberine	3 Studies recorded. The consensus is Increases📓, Click for details.
Herb or Spice	Carthamus tinctorius L,Safflower	1 Studies recorded. The consensus is Decreases📓, Click for details.
Herb or Spice	garlic (allium sativum)	1 Studies recorded. The consensus is Decreases👶, Click for details.
Herb or Spice	grape seed extract	1 Studies recorded. The consensus is Decreases👶, Click for details.
Herb or Spice	Perilla frutescens(shiso)	1 Studies recorded. The consensus is Decreases👶, Click for details.
Herb or Spice	Sijunzi decoction	1 Studies recorded. The consensus is Increases📓, Click for details.
Miscellaneous, food additives, and other odd items	bile (acid/salts)	1 Studies recorded. The consensus is Decreases📓, Click for details.
Miscellaneous, food additives, and other odd items	isobutyric acid	1 Studies recorded. The consensus is Increases📓, Click for details.
Miscellaneous, food additives, and other odd items	isovaleric acid(fatty acid)	1 Studies recorded. The consensus is Increases📓, Click for details.
Prebiotics and similar	fructo-oligosaccharides (prebiotic)	3 Studies recorded. The consensus is Decreases👶📓, Click for details.
Prebiotics and similar	galacto-oligosaccharides (prebiotic)	1 Studies recorded. The consensus is Decreases📓, Click for details.
Prebiotics and similar	Human milk oligosaccharides (prebiotic, Holigos, Stachyose)	1 Studies recorded. The consensus is Increases📓, Click for details.
Prebiotics and similar	mastic gum (prebiotic)	1 Studies recorded. The consensus is Decreases👶, Click for details.
Prebiotics and similar	oligosaccharides (prebiotic)	1 Studies recorded. The consensus is Increases📓, Click for details.
Prebiotics and similar	resistant starch	2 Studies recorded. The consensus is Increases📓, Click for details.
Prebiotics and similar	ß-glucan	1 Studies recorded. The consensus is Decreases👶, Click for details.
Prescription - Other	atorvastatin (prescription)	1 Studies recorded. The consensus is Decreases📓, Click for details.
Prescription - Other	dopamine (prescription)	1 Studies recorded. The consensus is Increases📓, Click for details.
Prescription - Other	metformin (prescription)	1 Studies recorded. The consensus is Increases📓, Click for details.
Prescription - Other	proton-pump inhibitors (prescription)	1 Studies recorded. The consensus is Increases📓, Click for details.
Probiotics	bacillus subtilis (probiotics)	1 Studies recorded. The consensus is Increases📓, Click for details.
Probiotics	bifidobacterium (probiotics)	1 Studies recorded. The consensus is Decreases📓, Click for details.
Probiotics	bifidobacterium pseudocatenulatum li09,bifidobacterium catenulatum li10 (probiotics)	1 Studies recorded. The consensus is Decreases📓, Click for details.
Probiotics	candida albicans (prescription)	1 Studies recorded. The consensus is Increases📓, Click for details.
Probiotics	clostridium butyricum (probiotics),Miya,Miyarisan	1 Studies recorded. The consensus is Decreases📓, Click for details.
Probiotics	lactobacillus gasseri (probiotics)	1 Studies recorded. The consensus is Increases👶, Click for details.
Probiotics	lactobacillus kefiri (NOT KEFIR)	1 Studies recorded. The consensus is Decreases📓, Click for details.
Probiotics	lactobacillus plantarum (probiotics)	1 Studies recorded. The consensus is Decreases📓, Click for details.
Probiotics	lactobacillus rhamnosus (probiotics)	1 Studies recorded. The consensus is Decreases👪, Click for details.
Probiotics	saccharomyces boulardii (probiotics)	1 Studies recorded. The consensus is Increases📓, Click for details.
Sugar and similar	aspartame (sweetner)	1 Studies recorded. The consensus is Decreases👶, Click for details.
Sugar and similar	non-starch polysaccharides	1 Studies recorded. The consensus is Increases👶, Click for details.
Sugar and similar	polysorbate 80	1 Studies recorded. The consensus is Decreases📓, Click for details.
Sugar and similar	xylitol	1 Studies recorded. The consensus is Increases📓, Click for details.
Synthetic Impact	Citicoline	1 Studies recorded. The consensus is Decreases👪, Click for details.
Vitamins, Minerals and similar	fluorine	1 Studies recorded. The consensus is Decreases👶, Click for details.
Vitamins, Minerals and similar	iron	2 Studies recorded. The consensus is Increases📓, Click for details.
Vitamins, Minerals and similar	Vitamin B9,folic acid	1 Studies recorded. The consensus is Increases📓, Click for details.
Vitamins, Minerals and similar	vitamin d	1 Studies recorded. The consensus is Decreases👶, Click for details.
Vitamins, Minerals and similar	zinc	2 Studies recorded. The consensus is Decreases👶📓, Click for details.

Foods Containing the Porphyromonas bacteria

Data comes from FoodMicrobionet. For the meaning of weight, see that site. The bacteria does not need to be alive to have an effect.

Cheese with dietary fibers Weight: 0.6955 Beer Weight: 0.1696 Piedmont hard cheese Weight: 0.149 Cheese, Emmental Weight: 0.1328 Passito wine Weight: 0.1256 Cheese, Caciocavallo Weight: 0.05821 cow cheese, core, raw Weight: 0.04031 tomato sour soup metagenome Weight: 0.03826 Palm wine Weight: 0.03302 Surstromming - Fermented Herring (Sweden) Weight: 0.02804 Beer Sour Flanders Red Ale Weight: 0.02761 Fermented glutinous rice Weight: 0.01264 Sausage, Cyprus: Limassol Weight: 0.00939 Cheddar cheese Weight: 0.009019 Trentingrana Cheese (Italy) Weight: 0.006584 Brie cheese Weight: 0.005699 Dehulled maize dough, Ghana Weight: 0.004984 Picual olives Weight: 0.003321 Robiola di Roccaverano Cheese (Italy) Weight: 0.001867 Gruyere cheese Weight: 0.001831 yoghurt fermentation Weight: 0.001751

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