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Bone Health: Vitamin K2 is essential for bone metabolism and helps regulate calcium balance in the body. It activates osteocalcin, a protein involved in bone mineralization. Adequate vitamin K2 intake has been associated with improved bone mineral density and reduced risk of fractures, particularly in postmenopausal women and elderly individuals.
Cardiovascular Health: Vitamin K2 is thought to have protective effects on the cardiovascular system by preventing calcium deposition in the arteries and promoting arterial elasticity. It activates matrix Gla-protein (MGP), which inhibits vascular calcification. Some research suggests that adequate vitamin K2 intake may reduce the risk of coronary artery calcification and cardiovascular events.
Blood Clotting: Like vitamin K1, vitamin K2 plays a role in blood clotting by activating clotting factors in the liver. However, vitamin K2 is primarily involved in extrahepatic tissues such as bones and blood vessels, whereas vitamin K1 is mainly involved in hepatic functions.
Cancer Prevention: Some studies suggest that vitamin K2 may have anticancer properties and could help reduce the risk of certain types of cancer, including prostate, liver, and lung cancer. However, more research is needed to establish a definitive link.
Dental Health: Vitamin K2 may play a role in dental health by promoting tooth mineralization and preventing dental cavities. It may also help maintain healthy gums and prevent periodontal disease.
Brain Health: Emerging evidence suggests that vitamin K2 may have neuroprotective effects and could help prevent neurodegenerative diseases such as Alzheimer's disease. Vitamin K2 may protect against oxidative stress and inflammation in the brain.
Diabetes Management: Some research indicates that vitamin K2 supplementation may improve insulin sensitivity and reduce the risk of type 2 diabetes. However, more studies are needed to confirm these effects.
Skin Health: Vitamin K2 may have benefits for skin health by promoting wound healing, reducing the appearance of bruises, and supporting overall skin integrity.
| Rank | Probiotic | Impact |
|---|
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
| Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
|---|---|---|---|
| Allergies | 0.6 | -0.6 | |
| Alopecia (Hair Loss) | 0.5 | -0.5 | |
| Alzheimer's disease | 0.6 | 0.6 | 0 |
| Ankylosing spondylitis | 0.2 | -0.2 | |
| Atherosclerosis | 0.2 | -0.2 | |
| Atrial fibrillation | 0.2 | -0.2 | |
| Autism | 0.2 | -0.2 | |
| Barrett esophagus cancer | 0.6 | -0.6 | |
| Brain Trauma | 0.2 | -0.2 | |
| Breast Cancer | 0.3 | 0.3 | |
| Carcinoma | 0.8 | 0.8 | 0 |
| Celiac Disease | 0.2 | 0.2 | |
| Chronic Kidney Disease | 0.2 | 0.2 | |
| Colorectal Cancer | 0.2 | 0.2 | |
| Constipation | 0.3 | 0.3 | |
| Coronary artery disease | 0.2 | -0.2 | |
| COVID-19 | 1.4 | 1.4 | |
| Crohn's Disease | 0.2 | 0.8 | -3 |
| Depression | 0.2 | 0.2 | 0 |
| Endometriosis | 0.6 | -0.6 | |
| Epilepsy | 0.2 | -0.2 | |
| erectile dysfunction | 0.2 | -0.2 | |
| Functional constipation / chronic idiopathic constipation | 0.3 | 0.3 | |
| Graves' disease | 0.2 | 1.1 | -4.5 |
| hypercholesterolemia (High Cholesterol) | 0.6 | -0.6 | |
| hyperglycemia | 0.6 | -0.6 | |
| Hyperlipidemia (High Blood Fats) | 0.2 | 0.2 | 0 |
| hypersomnia | 0.3 | 0.3 | |
| hypertension (High Blood Pressure | 0.8 | -0.8 | |
| Inflammatory Bowel Disease | 0.8 | 0.2 | 3 |
| Intelligence | 0.6 | 0.6 | |
| Intracranial aneurysms | 0.2 | 0.2 | |
| Liver Cirrhosis | 0.6 | -0.6 | |
| Long COVID | 1.4 | 2 | -0.43 |
| Metabolic Syndrome | 1.4 | -1.4 | |
| Mood Disorders | 0.8 | 0.4 | 1 |
| Multiple Sclerosis | 0.6 | 0.6 | |
| Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | 0.2 | -0.2 | |
| Obesity | 0.2 | 1.4 | -6 |
| pancreatic cancer | 0.2 | 0.2 | |
| Parkinson's Disease | 0.8 | -0.8 | |
| Premenstrual dysphoric disorder | 0.2 | -0.2 | |
| primary biliary cholangitis | 0.2 | 0.3 | -0.5 |
| rheumatoid arthritis (RA),Spondyloarthritis (SpA) | 0.2 | 0.2 | 0 |
| Schizophrenia | 0.6 | 0.2 | 2 |
| Stress / posttraumatic stress disorder | 1 | 0.6 | 0.67 |
| Tic Disorder | 0.2 | 0.2 | |
| Type 2 Diabetes | 1.4 | -1.4 | |
| Ulcerative colitis | 1.2 | 0.3 | 3 |
| Unhealthy Ageing | 0.6 | 0.6 |
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