🍽️ amisulpride,(prescription)

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  1. Depression: Amitriptyline is used to treat major depressive disorder, a condition characterized by persistent feelings of sadness, hopelessness, and loss of interest or pleasure in activities. It works by increasing the levels of certain neurotransmitters, such as serotonin and norepinephrine, in the brain, which helps improve mood and alleviate depressive symptoms.

  2. Anxiety Disorders: In addition to depression, amitriptyline may also be used off-label to treat certain anxiety disorders, such as generalized anxiety disorder (GAD) and panic disorder. It may help reduce anxiety symptoms, including excessive worry, nervousness, and panic attacks.

  3. Chronic Pain: Amitriptyline is sometimes prescribed off-label for the management of chronic pain conditions, such as neuropathic pain, fibromyalgia, and migraine headaches. It may help alleviate pain by modulating neurotransmitter activity and by exerting analgesic effects.

  4. Side Effects: Common side effects of amitriptyline may include drowsiness, dizziness, dry mouth, blurred vision, constipation, urinary retention, weight gain, and sexual dysfunction. These side effects are usually dose-dependent and may improve over time as the body adjusts to the medication. However, if they persist or become bothersome, it's important to consult a healthcare professional.

  5. Orthostatic Hypotension: Amitriptyline can cause a drop in blood pressure upon standing up from a sitting or lying position, leading to symptoms such as dizziness or lightheadedness. Patients should be cautious when changing positions, particularly if they are prone to orthostatic hypotension.

  6. Cardiac Effects: Tricyclic antidepressants, including amitriptyline, can have effects on the cardiovascular system, including changes in heart rate, rhythm, and conduction. Patients with pre-existing cardiac conditions, such as heart failure or conduction abnormalities, should use amitriptyline with caution and under the guidance of a healthcare professional.

  7. Anticholinergic Effects: Amitriptyline has significant anticholinergic properties, which can lead to side effects such as dry mouth, constipation, urinary retention, blurred vision, and cognitive impairment, particularly in elderly patients. These effects may increase the risk of falls and cognitive decline in older adults.

  8. Serotonin Syndrome: In rare cases, amitriptyline can cause serotonin syndrome, a potentially life-threatening condition characterized by symptoms such as agitation, confusion, hallucinations, rapid heart rate, high blood pressure, fever, excessive sweating, tremors, and muscle rigidity. Patients should seek immediate medical attention if they experience any of these symptoms.

  9. Suicidal Thoughts: Like other antidepressant medications, amitriptyline may increase the risk of suicidal thoughts or behaviors, particularly in children, adolescents, and young adults. Patients should be closely monitored for worsening depression or suicidal ideation, especially when starting or changing the dosage of amitriptyline.

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βš—οΈ Compensation for antibiotic usage

Data Contradictions β€” Limits of Certainity

Impacted of amisulpride,(prescription) On Probiotics

Rank Probiotic Impact
species Akkermansia muciniphila Reduces

Bacteria Impacted by amisulpride,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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Taxonomy Rank Effect Citations Notation
Akkermansiaceae family Decreases 👪 Source Study
Lacrimispora genus Decreases 👪 Source Study
Segatella genus Decreases 👪 Source Study
Mediterraneibacter genus Decreases 👪 Source Study
Roseburia genus Decreases 👪 Source Study
Thomasclavelia genus Decreases 👪 Source Study
Akkermansia genus Decreases 📓 Source Study
unclassified Robinsoniella no rank Decreases ⚗️ Source Study
unclassified Fusobacterium no rank Decreases ⚗️ Source Study
unclassified Negativicoccus no rank Decreases ⚗️ Source Study
environmental samples no rank Decreases 👶 Source Study
unclassified Akkermansia no rank Decreases 👶 Source Study
Eggerthellales order Decreases ⚗️ Source Study
Lacrimispora saccharolytica species Decreases 📓 Source Study
Segatella copri species Decreases 📓 Source Study Over 70%ile Indicator of mycotoxin present
Anaerofustis stercorihominis species Decreases ⚗️ Source Study
Asaccharospora irregularis species Decreases ⚗️ Source Study
[Ruminococcus] torques species Decreases 📓 Source Study
Negativicoccus sp. S5-A15 species Decreases ⚗️ Source Study
Paraprevotella clara species Decreases ⚗️ Source Study
Slackia sp. NATTS species Decreases ⚗️ Source Study
Pseudoflavonifractor capillosus species Decreases ⚗️ Source Study
[Collinsella] massiliensis species Decreases ⚗️ Source Study
Parvibacter caecicola species Decreases ⚗️ Source Study
Roseburia intestinalis species Decreases 📓 Source Study
Thomasclavelia ramosa species Decreases 📓 Source Study
Akkermansia muciniphila species Decreases 📓 Source Study
Akkermansia glycaniphila species Decreases 👶 Source Study
Coriobacterineae suborder Decreases ⚗️ Source Study
Chlamydiae/Verrucomicrobia group superphylum Decreases ⚗️ Source Study

Impact of amisulpride,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
ADHD 0 0
Age-Related Macular Degeneration and Glaucoma 0 0
Allergies 0.2 -0.2
Alzheimer's disease 0 0.2 0
Amyotrophic lateral sclerosis (ALS) Motor Neuron 0 0 0
Ankylosing spondylitis 0.2 0.2
Anorexia Nervosa 0 0
Antiphospholipid syndrome (APS) 0 0
Asthma 0 0
Atherosclerosis 0.1 -0.1
Atrial fibrillation 0.2 -0.2
Autism 0.4 0.3 0.33
Bipolar Disorder 0 0
Brain Trauma 0 0
Celiac Disease 0 0
Cerebral Palsy 0 0 0
Chronic Fatigue Syndrome 0.1 0.1
Chronic Kidney Disease 0.2 0 0
Chronic Lyme 0 0
Chronic Obstructive Pulmonary Disease (COPD) 0 0
Chronic Urticaria (Hives) 0.2 -0.2
Coagulation / Micro clot triggering bacteria 0 0
Colorectal Cancer 0 0
Constipation 0 0
COVID-19 0 0.3 0
Crohn's Disease 0 0 0
cystic fibrosis 0 0
deep vein thrombosis 0 0
Depression 0.4 0 0
Epilepsy 0 0 0
Fibromyalgia 0.1 0.2 -1
Functional constipation / chronic idiopathic constipation 0 0.4 0
gallstone disease (gsd) 0 0
Graves' disease 0 0
Hashimoto's thyroiditis 0.2 0.2
High Histamine/low DAO 0 0
hypercholesterolemia (High Cholesterol) 0 0
hyperglycemia 0 0 0
Hyperlipidemia (High Blood Fats) 0 0
hypertension (High Blood Pressure 0 0 0
Hypoxia 0 0
IgA nephropathy (IgAN) 0.2 -0.2
Inflammatory Bowel Disease 0 0.3 0
Insomnia 0 0
Intelligence 0.2 -0.2
Irritable Bowel Syndrome 0 0 0
Liver Cirrhosis 0 0 0
Long COVID 0 0 0
Low bone mineral density 0 0
Lung Cancer 0 0
ME/CFS without IBS 0.1 0.1
Metabolic Syndrome 0 0 0
Mood Disorders 0.4 0 0
multiple chemical sensitivity [MCS] 0 0
Multiple Sclerosis 0 0.2 0
Multiple system atrophy (MSA) 0 0
neuropathic pain 0 0
Neuropathy (all types) 0 0
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 0.2 0 0
Obesity 0.2 0 0
obsessive-compulsive disorder 0.4 -0.4
Osteoarthritis 0 0
Osteoporosis 0 0
Parkinson's Disease 0 0.1 0
Polycystic ovary syndrome 0 0
Psoriasis 0 0.2 0
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 0.2 0 0
Rosacea 0.2 0 0
Schizophrenia 0 0 0
Sjögren syndrome 0.2 0.2
Sleep Apnea 0 0
Stress / posttraumatic stress disorder 0 0 0
Systemic Lupus Erythematosus 0 0
Tic Disorder 0.2 -0.2
Tourette syndrome 0 0
Type 1 Diabetes 0 0
Type 2 Diabetes 0 0 0
Ulcerative colitis 0.3 -0.3
Unhealthy Ageing 0.2 0 0

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