🍽️ glipizide,(prescription)

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  1. Blood Glucose Control: Glipizide helps to lower blood sugar levels by stimulating the release of insulin from the pancreas. It is effective in controlling hyperglycemia (high blood sugar) in patients with type 2 diabetes mellitus.

  2. Insulin Secretagogue: As a sulfonylurea, glipizide acts as an insulin secretagogue, meaning it promotes the release of insulin from the beta cells of the pancreas. This mechanism helps to lower blood glucose levels by increasing insulin availability.

  3. Hypoglycemia: One of the main side effects of glipizide is hypoglycemia, or low blood sugar levels. This can occur if the dose of glipizide is too high relative to the individual's insulin needs or if meals are skipped or delayed.

  4. Weight Gain: Some individuals may experience weight gain while taking glipizide. This can be due to the medication's effect of increasing insulin levels, which can promote fat storage.

  5. Gastrointestinal Effects: Glipizide may cause gastrointestinal side effects such as nausea, vomiting, diarrhea, or abdominal discomfort in some patients. These effects are usually mild and transient.

  6. Skin Reactions: Rarely, glipizide may cause skin reactions such as rash or itching. If these symptoms occur, patients should consult their healthcare provider.

  7. Liver Function: Glipizide can affect liver function, although significant liver toxicity is rare. Liver function tests may be monitored periodically in patients taking glipizide, especially those with pre-existing liver conditions.

  8. Allergic Reactions: Some individuals may experience allergic reactions to glipizide, although these are rare. Symptoms of an allergic reaction may include rash, itching, swelling, dizziness, or difficulty breathing. Immediate medical attention is necessary if an allergic reaction occurs.

  9. Drug Interactions: Glipizide may interact with other medications, including other antidiabetic drugs, leading to changes in blood sugar levels or an increased risk of hypoglycemia or other adverse effects. It's important for patients to inform their healthcare providers about all medications they are taking.

  10. Cardiovascular Effects: While glipizide itself does not directly affect the cardiovascular system, maintaining good blood sugar control with medications like glipizide can reduce the risk of long-term cardiovascular complications associated with diabetes, such as heart disease and stroke.


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Data Contradictions β€” Limits of Certainity

Impacted of glipizide,(prescription) On Probiotics

Rank Probiotic Impact

Bacteria Impacted by glipizide,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.


Taxonomy Rank Effect Citations Notation
Streptococcus genus Decreases 👪 Source Study
Mediterraneibacter genus Decreases 👪 Source Study
Roseburia genus Decreases 👪 Source Study
Bilophila genus Decreases 👪 Source Study High Level Cause Brain Fog(Cognitive impairment)
unclassified Robinsoniella no rank Decreases ⚗️ Source Study
unclassified Fusobacterium no rank Decreases ⚗️ Source Study
unclassified Negativicoccus no rank Decreases ⚗️ Source Study
Eggerthellales order Decreases ⚗️ Source Study
Streptococcus salivarius species Decreases 📓 Source Study Infectious bacteria
[Ruminococcus] torques species Decreases 📓 Source Study
Anaerofustis stercorihominis species Decreases ⚗️ Source Study
Asaccharospora irregularis species Decreases ⚗️ Source Study
Negativicoccus sp. S5-A15 species Decreases ⚗️ Source Study
Paraprevotella clara species Decreases ⚗️ Source Study
Slackia sp. NATTS species Decreases ⚗️ Source Study
Pseudoflavonifractor capillosus species Decreases ⚗️ Source Study
[Collinsella] massiliensis species Decreases ⚗️ Source Study
Parvibacter caecicola species Decreases ⚗️ Source Study
Roseburia hominis species Decreases 📓 Source Study
Bilophila wadsworthia species Decreases 📓 Source Study
Coriobacterineae suborder Decreases ⚗️ Source Study
Chlamydiae/Verrucomicrobia group superphylum Decreases ⚗️ Source Study

Impact of glipizide,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0 0
ADHD 0 0
Age-Related Macular Degeneration and Glaucoma 0 0
Alzheimer's disease 0 0.8 0
Ankylosing spondylitis 0.5 0.5
Anorexia Nervosa 0 0
Antiphospholipid syndrome (APS) 0.5 0 0
Asthma 0 0
Atherosclerosis 0 0
Atrial fibrillation 0.5 0 0
Autism 1.2 0.5 1.4
Barrett esophagus cancer 0.5 -0.5
Bipolar Disorder 0 0 0
Brain Trauma 0 0
Carcinoma 0.5 0.5
Celiac Disease 0.5 0 0
Cerebral Palsy 0.5 0 0
Chronic Fatigue Syndrome 0.6 0.5 0.2
Chronic Kidney Disease 0.7 0 0
Chronic Lyme 0 0
Chronic Obstructive Pulmonary Disease (COPD) 1.4 0 0
Chronic Urticaria (Hives) 0.5 0.5
Coagulation / Micro clot triggering bacteria 0.5 0.5 0
Colorectal Cancer 1 1
Constipation 0 0
COVID-19 0.5 1.5 -2
Crohn's Disease 0 0 0
cystic fibrosis 0 0
deep vein thrombosis 0.5 -0.5
Depression 0.9 0.5 0.8
Dermatomyositis 0.5 0.5
Eczema 1.4 -1.4
Endometriosis 0.5 0.5
Epilepsy 0.5 0.5
Fibromyalgia 0 0
Functional constipation / chronic idiopathic constipation 0.7 -0.7
gallstone disease (gsd) 0 0
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 0.5 -0.5
Glioblastoma 0.5 -0.5
Graves' disease 0 0
Halitosis 0.5 -0.5
Hashimoto's thyroiditis 0.7 0 0
Hidradenitis Suppurativa 0.5 0.5
Histamine Issues 0 0.3 0
hypersomnia 0 0
hypertension (High Blood Pressure 0.5 0.6 -0.2
Inflammatory Bowel Disease 1.4 0 0
Insomnia 0.5 0 0
Irritable Bowel Syndrome 0 0 0
Liver Cirrhosis 0.5 0.5 0
Long COVID 0.5 0 0
Low bone mineral density 0 0
Mast Cell Issues / mastitis 0.5 0.5
ME/CFS with IBS 0.5 0.5
ME/CFS without IBS 0.6 0.6
Metabolic Syndrome 0.5 0.6 -0.2
Mood Disorders 0.9 0.5 0.8
multiple chemical sensitivity [MCS] 1.4 1.4
Multiple Sclerosis 1.5 0.5 2
Multiple system atrophy (MSA) 0.1 0.1
neuropathic pain 0.1 -0.1
Neuropathy (all types) 0.5 0.5
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 0.5 0.5
Obesity 1.3 1 0.3
obsessive-compulsive disorder 0.5 0.7 -0.4
Osteoarthritis 0.5 0.5
pancreatic cancer 0.5 0.5
Parkinson's Disease 0.5 0.5 0
Polycystic ovary syndrome 0 0
Psoriasis 0.5 0 0
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 0.5 0 0
Rosacea 0.7 0 0
Schizophrenia 0 0 0
scoliosis 0 0
Sjögren syndrome 0.5 0.5
Sleep Apnea 0 0
Small Intestinal Bacterial Overgrowth (SIBO) 0.5 0.5
Stress / posttraumatic stress disorder 0 0 0
Systemic Lupus Erythematosus 0.5 0 0
Type 1 Diabetes 0 0.5 0
Type 2 Diabetes 0.5 0.5 0
Ulcerative colitis 0.5 0 0
Unhealthy Ageing 1.2 0 0

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