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Antihistaminic Effects: Pheniramine maleate works by blocking histamine receptors, thereby reducing the effects of histamine release in the body. This action helps alleviate allergy symptoms such as itching, sneezing, and runny nose.
Allergy Relief: Pheniramine maleate is commonly used to relieve symptoms associated with allergic rhinitis (hay fever), allergic conjunctivitis, and other allergic reactions to environmental allergens such as pollen, dust mites, pet dander, and mold.
Nasal Congestion: Pheniramine maleate may help relieve nasal congestion by reducing swelling and inflammation of the nasal passages, allowing for easier breathing.
Itchy Skin Relief: Itchy skin conditions such as hives (urticaria) and insect bites may be relieved by pheniramine maleate due to its antipruritic (anti-itch) effects.
Sedation: Pheniramine maleate has sedative effects and may cause drowsiness or sleepiness, particularly when taken at higher doses or in combination with other sedating medications. This sedative effect can be beneficial for individuals experiencing allergic symptoms that disrupt sleep, but it can also impair alertness and cognitive function.
Dry Mouth: Pheniramine maleate may cause dry mouth as a side effect due to its anticholinergic properties, which can reduce saliva production.
Blurred Vision: Some individuals may experience temporary blurred vision while taking pheniramine maleate, especially at higher doses. This effect is typically mild and transient.
Urinary Retention: Pheniramine maleate can cause urinary retention, particularly in individuals with benign prostatic hyperplasia (enlarged prostate) or other conditions affecting bladder function. Patients experiencing difficulty urinating should seek medical advice.
Constipation: Pheniramine maleate may lead to constipation as a result of its anticholinergic effects, which can slow down bowel motility.
Dizziness: Dizziness or lightheadedness may occur as a side effect of pheniramine maleate, especially in individuals prone to low blood pressure or those taking other medications that can cause dizziness.
Increased Intraocular Pressure: Pheniramine maleate may increase intraocular pressure (pressure within the eye), particularly in individuals with glaucoma. Patients with pre-existing eye conditions should use pheniramine maleate with caution and under the supervision of an ophthalmologist.
Interactions: Pheniramine maleate may interact with other medications, including sedatives, tranquilizers, and central nervous system depressants, leading to additive effects on sedation and drowsiness. Patients should consult their healthcare provider or pharmacist before combining pheniramine maleate with other medications.
| Rank | Probiotic | Impact |
|---|---|---|
| genus | Bifidobacterium | Reduces |
| species | Bifidobacterium adolescentis | Reduces |
| species | Bifidobacterium longum | Reduces |
| subspecies | Bifidobacterium longum subsp. infantis | Reduces |
| subspecies | Bifidobacterium longum subsp. longum | Reduces |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
| Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
|---|---|---|---|
| Acne | 0 | 0 | |
| ADHD | 0.2 | 0.2 | |
| Age-Related Macular Degeneration and Glaucoma | 0.1 | 0.1 | |
| Allergic Rhinitis (Hay Fever) | 0.2 | -0.2 | |
| Allergies | 0.1 | 0.6 | -5 |
| Allergy to milk products | 0 | 0 | |
| Alzheimer's disease | 0 | 0.4 | 0 |
| Amyotrophic lateral sclerosis (ALS) Motor Neuron | 0.3 | 0.3 | |
| Ankylosing spondylitis | 0.1 | 0.1 | 0 |
| Anorexia Nervosa | 0.2 | -0.2 | |
| Antiphospholipid syndrome (APS) | 0.3 | 0.3 | |
| Asthma | 0.5 | 0.6 | -0.2 |
| Atherosclerosis | 0 | 0.1 | 0 |
| Atrial fibrillation | 0.2 | 0 | 0 |
| Autism | 0.5 | 0.6 | -0.2 |
| Barrett esophagus cancer | 0.1 | 0 | 0 |
| Biofilm | 1 | 1 | |
| Bipolar Disorder | 0.1 | -0.1 | |
| Brain Trauma | 0 | 0.3 | 0 |
| Cancer (General) | 0 | 0.9 | 0 |
| Carcinoma | 0.1 | 0.1 | 0 |
| Celiac Disease | 0.4 | 0.3 | 0.33 |
| Cerebral Palsy | 0.1 | 0.1 | 0 |
| Chronic Fatigue Syndrome | 0.3 | 0.2 | 0.5 |
| Chronic Kidney Disease | 0 | 0.2 | 0 |
| Chronic Lyme | 0.1 | -0.1 | |
| Chronic Obstructive Pulmonary Disease (COPD) | 0.2 | 0.2 | 0 |
| Chronic Urticaria (Hives) | 0.1 | 0.1 | |
| Coagulation / Micro clot triggering bacteria | 1 | 0.1 | 9 |
| Colorectal Cancer | 0.2 | 0 | 0 |
| Constipation | 0.1 | 0.1 | 0 |
| Coronary artery disease | 0.1 | -0.1 | |
| COVID-19 | 0.3 | 0.5 | -0.67 |
| Crohn's Disease | 0.2 | 0.4 | -1 |
| cystic fibrosis | 0.8 | 0.1 | 7 |
| deep vein thrombosis | 1 | 0.1 | 9 |
| Depression | 0.7 | 0.2 | 2.5 |
| Dermatomyositis | 0 | 0 | 0 |
| Eczema | 0.1 | 0.1 | 0 |
| Endometriosis | 0.1 | 0.2 | -1 |
| Eosinophilic Esophagitis | 0.1 | -0.1 | |
| Epilepsy | 0.1 | 0 | 0 |
| Fibromyalgia | 0.1 | 0 | 0 |
| Functional constipation / chronic idiopathic constipation | 0.7 | 0.1 | 6 |
| gallstone disease (gsd) | 0.1 | 0.1 | 0 |
| Gastroesophageal reflux disease (Gerd) including Barrett's esophagus | 0.1 | 0 | 0 |
| Generalized anxiety disorder | 0.1 | -0.1 | |
| Glioblastoma | 0 | 0 | |
| Graves' disease | 0 | 0.1 | 0 |
| Halitosis | 0.1 | 0 | 0 |
| Hashimoto's thyroiditis | 0.1 | 0 | 0 |
| Hidradenitis Suppurativa | 0.3 | 0.1 | 2 |
| High Histamine/low DAO | 0.3 | 0 | 0 |
| hypercholesterolemia (High Cholesterol) | 0 | 0 | |
| hyperglycemia | 0.3 | 0 | 0 |
| Hyperlipidemia (High Blood Fats) | 0 | 0 | |
| hypertension (High Blood Pressure | 0.3 | 0.6 | -1 |
| Hypothyroidism | 0 | 0 | |
| IgA nephropathy (IgAN) | 0.2 | -0.2 | |
| Inflammatory Bowel Disease | 0.4 | 0.3 | 0.33 |
| Insomnia | 0 | 0.2 | 0 |
| Irritable Bowel Syndrome | 0.6 | 0.2 | 2 |
| Liver Cirrhosis | 1 | 0.4 | 1.5 |
| Long COVID | 0.3 | 0.5 | -0.67 |
| Low bone mineral density | 0.2 | -0.2 | |
| Mast Cell Issues / mastitis | 0 | 0 | 0 |
| ME/CFS with IBS | 0 | 0 | 0 |
| ME/CFS without IBS | 0.2 | 0 | 0 |
| Menopause | 0.1 | 0.1 | |
| Metabolic Syndrome | 0.4 | 0.6 | -0.5 |
| Mood Disorders | 0.8 | 0.2 | 3 |
| multiple chemical sensitivity [MCS] | 0.2 | 0.2 | |
| Multiple Sclerosis | 0.2 | 0.3 | -0.5 |
| Multiple system atrophy (MSA) | 0.1 | 0 | 0 |
| neuropathic pain | 0.2 | -0.2 | |
| Neuropathy (all types) | 0 | 0 | |
| neuropsychiatric disorders (PANDAS, PANS) | 0 | 0 | |
| Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | 0 | 0.3 | 0 |
| NonCeliac Gluten Sensitivity | 0 | 0 | 0 |
| Obesity | 0.5 | 0.4 | 0.25 |
| obsessive-compulsive disorder | 0.5 | 0.1 | 4 |
| Osteoarthritis | 0 | 0 | |
| Osteoporosis | 0.1 | 0.1 | |
| pancreatic cancer | 0.1 | 0.1 | |
| Parkinson's Disease | 0.3 | 0.5 | -0.67 |
| Polycystic ovary syndrome | 0.1 | -0.1 | |
| Postural orthostatic tachycardia syndrome | 0 | 0 | |
| Premenstrual dysphoric disorder | 0 | 0 | |
| Psoriasis | 0.6 | 0.1 | 5 |
| rheumatoid arthritis (RA),Spondyloarthritis (SpA) | 0.7 | 0.2 | 2.5 |
| Rosacea | 0.1 | 0.1 | 0 |
| Schizophrenia | 0.4 | 0.1 | 3 |
| scoliosis | 0.2 | -0.2 | |
| Sjögren syndrome | 0.2 | 0.1 | 1 |
| Sleep Apnea | 0 | 0.1 | 0 |
| Slow gastric motility / Gastroparesis | 0.1 | 0 | 0 |
| Small Intestinal Bacterial Overgrowth (SIBO) | 0.8 | 0.1 | 7 |
| Stress / posttraumatic stress disorder | 0.3 | 0.1 | 2 |
| Systemic Lupus Erythematosus | 0.1 | 0.2 | -1 |
| Tic Disorder | 0 | 0 | 0 |
| Type 1 Diabetes | 0.1 | 0.5 | -4 |
| Type 2 Diabetes | 0.4 | 0.4 | 0 |
| Ulcerative colitis | 0.3 | 0.1 | 2 |
| Unhealthy Ageing | 0.1 | 0.1 | 0 |
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