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🍽️ lamotrigine,(prescription)

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  1. Epilepsy: Lamotrigine is commonly prescribed as an antiepileptic medication to control seizures in various types of epilepsy, including focal seizures, generalized tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome. It helps reduce the frequency and severity of seizures by regulating abnormal electrical activity in the brain.

  2. Bipolar Disorder: Lamotrigine is also approved for the maintenance treatment of bipolar disorder, specifically to prevent or reduce the frequency of mood episodes, including manic, hypomanic, depressive, or mixed episodes. It is often used in conjunction with other mood stabilizers or antidepressants to help stabilize mood and prevent relapse.

  3. Depression: In some cases, lamotrigine may be used off-label as an adjunctive treatment for depression, particularly in individuals with bipolar disorder who have not responded adequately to standard antidepressant therapy. It may help alleviate depressive symptoms and improve overall mood stability.

  4. Postherpetic Neuralgia: Postherpetic neuralgia is a complication of shingles (herpes zoster) characterized by persistent pain in the area affected by the shingles rash. Lamotrigine may be used off-label to help manage neuropathic pain associated with postherpetic neuralgia, although its efficacy for this indication is less established compared to other medications such as anticonvulsants or tricyclic antidepressants.

  5. Other Neuropsychiatric Conditions: There is emerging evidence suggesting potential benefits of lamotrigine in the treatment of other neuropsychiatric conditions, such as borderline personality disorder, attention-deficit/hyperactivity disorder (ADHD), and anxiety disorders. However, further research is needed to fully understand its effectiveness and safety in these conditions.

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βš—οΈ Compensation for antibiotic usage

Data Contradictions β€” Limits of Certainity

Impacted of lamotrigine,(prescription) On Probiotics

Rank Probiotic Impact
species Bacteroides uniformis Reduces
species Escherichia coli Reduces

Bacteria Impacted by lamotrigine,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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Taxonomy Rank Effect Citations Notation
Bilophila genus Decreases 👪 Source Study High Level Cause Brain Fog(Cognitive impairment)
Escherichia genus Decreases 👪 Source Study
Roseburia genus Decreases 👪 Source Study
Eggerthella genus Decreases 👪 Source Study
Agathobacter genus Decreases 👪 Source Study
Veillonella genus Decreases 👪 Source Study
Mediterraneibacter genus Decreases 👪 Source Study
Streptococcus genus Decreases 👪 Source Study
Bacteroides genus Decreases 👪 Source Study
Phocaeicola genus Decreases 👪 Source Study
Enterocloster genus Decreases 👪 Source Study
Fusobacterium genus Decreases 👪 Source Study Periodontal disease, Lemierre syndrome, skin ulcers
Coprococcus genus Decreases 👪 Source Study
Segatella genus Decreases 👪 Source Study
Escherichia coli O1:K1:H7 no rank Decreases 👶 Source Study
Escherichia coli O139:H1 no rank Decreases 👶 Source Study
Escherichia coli O141:H4 no rank Decreases 👶 Source Study
Escherichia coli O145:H34 no rank Decreases 👶 Source Study
Escherichia coli O15:H12 no rank Decreases 👶 Source Study
Escherichia coli O155:H21 no rank Decreases 👶 Source Study
Escherichia coli O158:H23 no rank Decreases 👶 Source Study
Escherichia coli O16:H48 no rank Decreases 👶 Source Study
Escherichia coli O170:H18 no rank Decreases 👶 Source Study
Escherichia coli O18ac:H14 no rank Decreases 👶 Source Study
Escherichia coli O19:H7 no rank Decreases 👶 Source Study
Escherichia coli O2:K1:H4 no rank Decreases 👶 Source Study
Escherichia coli O2:K1:H5 no rank Decreases 👶 Source Study
Escherichia coli O2:K1:H7 no rank Decreases 👶 Source Study
Escherichia coli O20:H12 no rank Decreases 👶 Source Study
Escherichia coli O25:H16 no rank Decreases 👶 Source Study
Escherichia coli O55:H7 no rank Decreases 👶 Source Study
Escherichia coli O68:H12 no rank Decreases 👶 Source Study
Escherichia coli O7:H15 no rank Decreases 👶 Source Study
Escherichia coli O78:H51 no rank Decreases 👶 Source Study
Escherichia coli O80:H26 no rank Decreases 👶 Source Study
Escherichia coli O84:H7 no rank Decreases 👶 Source Study
Escherichia coli O85:H1 no rank Decreases 👶 Source Study
Escherichia coli O121 serogroup Decreases 👶 Source Study
Escherichia coli O145 serogroup Decreases 👶 Source Study
Escherichia coli O155 serogroup Decreases 👶 Source Study
Escherichia coli O157 serogroup Decreases 👶 Source Study
Escherichia coli O177 serogroup Decreases 👶 Source Study
Escherichia coli O26 serogroup Decreases 👶 Source Study
Escherichia coli O3 serogroup Decreases 👶 Source Study
Escherichia coli O43 serogroup Decreases 👶 Source Study
Escherichia coli O78 serogroup Decreases 👶 Source Study
Escherichia coli O86 serogroup Decreases 👶 Source Study
Escherichia coli O91 serogroup Decreases 👶 Source Study
Escherichia coli H20 serotype Decreases 👶 Source Study
Escherichia coli O1:H42 serotype Decreases 👶 Source Study
Escherichia coli O1:HNT serotype Decreases 👶 Source Study
Escherichia coli O10:H32 serotype Decreases 👶 Source Study
Escherichia coli O100:H21 serotype Decreases 👶 Source Study
Escherichia coli O103:H2 serotype Decreases 👶 Source Study
Escherichia coli O104:H4 serotype Decreases 👶 Source Study
Escherichia coli O111:H- serotype Decreases 👶 Source Study
Escherichia coli O111:H8 serotype Decreases 👶 Source Study
Escherichia coli O111:NM serotype Decreases 👶 Source Study
Escherichia coli O112ab:H8 serotype Decreases 👶 Source Study
Escherichia coli O112ac:H19 serotype Decreases 👶 Source Study
Escherichia coli O113:H21 serotype Decreases 👶 Source Study
Escherichia coli O114:H49 serotype Decreases 👶 Source Study
Escherichia coli O121:H19 serotype Decreases 👶 Source Study
Escherichia coli O125ac:K+:H10 serotype Decreases 👶 Source Study
Escherichia coli O126:H45 serotype Decreases 👶 Source Study
Escherichia coli O127:H6 serotype Decreases 👶 Source Study
Escherichia coli O128ac:H12 serotype Decreases 👶 Source Study
Escherichia coli O139:H28 serotype Decreases 👶 Source Study
Escherichia coli O145:H25 serotype Decreases 👶 Source Study
Escherichia coli O145:H28 serotype Decreases 👶 Source Study
Escherichia coli O145:NM serotype Decreases 👶 Source Study
Escherichia coli O15:H18 serotype Decreases 👶 Source Study
Escherichia coli O150:H6 serotype Decreases 👶 Source Study
Escherichia coli O152:H23 serotype Decreases 👶 Source Study
Escherichia coli O157:H- serotype Decreases 👶 Source Study
Escherichia coli O157:H43 serotype Decreases 👶 Source Study
Escherichia coli O157:H7 serotype Decreases 👶 Source Study bloody diarrhea
Escherichia coli O16:H6 serotype Decreases 👶 Source Study
Escherichia coli O167:H26 serotype Decreases 👶 Source Study
Escherichia coli O174:H21 serotype Decreases 👶 Source Study
Escherichia coli O176:H45 serotype Decreases 👶 Source Study
Escherichia coli O2:H6 serotype Decreases 👶 Source Study
Escherichia coli O2:K2:H1 serotype Decreases 👶 Source Study
Escherichia coli O25:H1 serotype Decreases 👶 Source Study
Escherichia coli O25:NM serotype Decreases 👶 Source Study
Escherichia coli O26:H11 serotype Decreases 👶 Source Study
Escherichia coli O44:H18 serotype Decreases 👶 Source Study
Escherichia coli O45:H2 serotype Decreases 👶 Source Study
Escherichia coli O6:H16 serotype Decreases 👶 Source Study
Escherichia coli O6:K2:H1 serotype Decreases 👶 Source Study
Escherichia coli O7:H4 serotype Decreases 👶 Source Study
Escherichia coli O7:K1 serotype Decreases 👶 Source Study
Escherichia coli O78:H4 serotype Decreases 👶 Source Study
Escherichia coli O8:H8 serotype Decreases 👶 Source Study
Escherichia coli O89m:H10 serotype Decreases 👶 Source Study
Escherichia coli O89m:H9 serotype Decreases 👶 Source Study
Escherichia coli O9:H10 serotype Decreases 👶 Source Study
Escherichia coli O99:H6 serotype Decreases 👶 Source Study
Bilophila wadsworthia species Decreases 📓 Source Study
Escherichia coli species Decreases 📓 Source Study Diarrheal disease in children and travelers, Foodborne diarrhea outbreaks, hemorrhagic colitis, hemolytic-uremic syndrome
Roseburia intestinalis species Decreases 📓 Source Study
Bacteroides xylanisolvens species Decreases 📓 Source Study
Eggerthella lenta species Decreases 📓 Source Study
Agathobacter rectalis species Decreases 📓 Source Study
Veillonella parvula species Decreases 📓 Source Study
Mediterraneibacter gnavus species Decreases 📓 Source Study
Bacteroides fragilis species Decreases 📓 Source Study H02076 Bacteroides infection
Streptococcus parasanguinis species Decreases 📓 Source Study
Phocaeicola vulgatus species Decreases 📓 Source Study
Enterocloster bolteae species Decreases 📓 Source Study
Fusobacterium nucleatum species Decreases 📓 Source Study Infectious bacteria
Bacteroides uniformis species Decreases 📓 Source Study Infectious bacteria
Coprococcus comes species Decreases 📓 Source Study
Segatella copri species Decreases 📓 Source Study Over 70%ile Indicator of mycotoxin present
Fusobacterium nucleatum subsp. nucleatum subspecies Decreases 👶 Source Study

Impact of lamotrigine,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0.5 0.5
ADHD 0.5 0.2 1.5
Age-Related Macular Degeneration and Glaucoma 0.2 0.2
Allergic Rhinitis (Hay Fever) 0.6 0.6
Allergies 1 0 0
Allergy to milk products 0.6 0.3 1
Alzheimer's disease 1.2 2.2 -0.83
Amyotrophic lateral sclerosis (ALS) Motor Neuron 0.5 0.5 0
Ankylosing spondylitis 1.1 0.4 1.75
Anorexia Nervosa 0.5 -0.5
Antiphospholipid syndrome (APS) 1.1 0.5 1.2
Asthma 0.4 0.3 0.33
Atherosclerosis 0 0.7 0
Atrial fibrillation 0.6 0.8 -0.33
Autism 1.8 2.1 -0.17
Barrett esophagus cancer 0.2 0.1 1
benign prostatic hyperplasia 0.3 0.3
Biofilm 1.1 1.1
Bipolar Disorder 0.8 0.6 0.33
Brain Trauma 0.3 -0.3
Carcinoma 1.1 0.1 10
Celiac Disease 1.1 0.7 0.57
Cerebral Palsy 0.3 0.3 0
Chronic Fatigue Syndrome 1.9 1.9 0
Chronic Kidney Disease 0.8 0.6 0.33
Chronic Lyme 0.3 -0.3
Chronic Obstructive Pulmonary Disease (COPD) 0.5 0.2 1.5
Chronic Urticaria (Hives) 1.1 0.3 2.67
Coagulation / Micro clot triggering bacteria 0.9 0.3 2
Colorectal Cancer 1.5 0.2 6.5
Constipation 0.6 0.2 2
Coronary artery disease 0.4 0.2 1
COVID-19 1.8 1.9 -0.06
Crohn's Disease 2.6 1 1.6
cystic fibrosis 0.8 0.3 1.67
deep vein thrombosis 0.8 0.3 1.67
Depression 1.9 1.4 0.36
Dermatomyositis 0.1 0.1
Eczema 0.7 0.4 0.75
Endometriosis 1 0.2 4
Eosinophilic Esophagitis 0 0.2 0
Epilepsy 0.8 0.1 7
Fibromyalgia 0.2 0.2 0
Functional constipation / chronic idiopathic constipation 1.8 0.6 2
gallstone disease (gsd) 0.4 0.3 0.33
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 0.6 0.1 5
Generalized anxiety disorder 1.1 0.1 10
Glioblastoma 0.1 -0.1
Gout 0 0
Graves' disease 0.1 0.2 -1
Halitosis 0.3 0.1 2
Hashimoto's thyroiditis 0.3 0.6 -1
Hidradenitis Suppurativa 0.6 0.2 2
High Histamine/low DAO 0.8 0.8
hyperglycemia 0.3 0.1 2
hypersomnia 0.5 -0.5
hypertension (High Blood Pressure 0.5 1.2 -1.4
Hypothyroidism 0.2 -0.2
Hypoxia 0.1 0.1
IgA nephropathy (IgAN) 0.3 -0.3
Inflammatory Bowel Disease 1.7 1.6 0.06
Insomnia 0.2 0.3 -0.5
Intelligence 0 0 0
Intracranial aneurysms 0.1 0.1
Irritable Bowel Syndrome 1.3 0.7 0.86
Liver Cirrhosis 1.4 1.1 0.27
Long COVID 1.6 1 0.6
Low bone mineral density 0.2 -0.2
Lung Cancer 0.3 0.3
Mast Cell Issues / mastitis 0.4 0 0
ME/CFS with IBS 0.2 0.1 1
ME/CFS without IBS 0.9 0.1 8
Metabolic Syndrome 2.4 1.4 0.71
Mood Disorders 2.7 1.6 0.69
multiple chemical sensitivity [MCS] 0.3 0.3
Multiple Sclerosis 1.4 1.1 0.27
Multiple system atrophy (MSA) 0.2 0.2
neuropathic pain 0.1 -0.1
Neuropathy (all types) 0.1 0.3 -2
neuropsychiatric disorders (PANDAS, PANS) 0.5 0.5
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 0.4 0.5 -0.25
NonCeliac Gluten Sensitivity 0.2 0.1 1
Obesity 1.4 0.2 6
obsessive-compulsive disorder 1.6 0.6 1.67
Osteoarthritis 0.7 0.7
Osteoporosis 0.7 0.1 6
pancreatic cancer 0.1 0.1
Parkinson's Disease 1.9 1.7 0.12
Polycystic ovary syndrome 0.6 0.2 2
Postural orthostatic tachycardia syndrome 0 0
primary biliary cholangitis 0 0
Psoriasis 1 0.4 1.5
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 1.7 0.8 1.13
Rosacea 0.2 -0.2
Schizophrenia 1.1 0.2 4.5
scoliosis 0 0.5 0
Sjögren syndrome 0.8 0.3 1.67
Sleep Apnea 0 0.5 0
Slow gastric motility / Gastroparesis 0.8 0.8
Small Intestinal Bacterial Overgrowth (SIBO) 0.7 0.7
Stress / posttraumatic stress disorder 0.9 0.7 0.29
Systemic Lupus Erythematosus 1.8 0.2 8
Tic Disorder 0.2 0 0
Tourette syndrome 0.1 -0.1
Type 1 Diabetes 1.4 0.5 1.8
Type 2 Diabetes 2.6 1.5 0.73
Ulcerative colitis 1 1 0
Unhealthy Ageing 1.9 0.6 2.17
Vitiligo 0.4 0 0

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