🍽️ etodolac,(prescription)

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  1. Pain Relief: Etodolac is effective in relieving pain of mild to moderate intensity. It works by inhibiting the production of prostaglandins, which are chemicals in the body that contribute to pain and inflammation.

  2. Anti-inflammatory Action: In addition to its analgesic effects, etodolac exhibits anti-inflammatory properties by reducing inflammation in affected tissues. This can help alleviate symptoms such as swelling, redness, and stiffness associated with inflammatory conditions like arthritis, bursitis, and tendonitis.

  3. Musculoskeletal Conditions: Etodolac is commonly prescribed for the management of pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and other musculoskeletal disorders.

  4. Acute Pain: It is also used for the short-term treatment of acute pain, such as pain following dental procedures, surgery, or injury.

  5. Fever Reduction: Etodolac may help reduce fever by acting on the hypothalamic heat-regulating center in the brain.

  6. Oral Administration: Etodolac is typically taken orally in the form of tablets or capsules. It is usually taken with food or milk to minimize gastrointestinal side effects.

  7. Extended-Release Formulations: Extended-release formulations of etodolac are available, which provide a prolonged duration of action and may require less frequent dosing compared to immediate-release formulations.

  8. Side Effects: Like other NSAIDs, etodolac may cause side effects, especially with prolonged or excessive use. Common side effects may include gastrointestinal upset, including stomach pain, nausea, vomiting, indigestion, and diarrhea. Other potential side effects include headache, dizziness, drowsiness, fluid retention, and allergic reactions.

  9. Gastrointestinal Safety: Etodolac is associated with a lower risk of gastrointestinal ulcers and bleeding compared to some other NSAIDs, but it still carries a risk, particularly in patients with a history of gastrointestinal problems, older adults, and those taking other medications that increase the risk of bleeding.

  10. Cardiovascular Risk: NSAIDs, including etodolac, may increase the risk of cardiovascular events such as heart attack and stroke, especially when used at high doses or for long periods. Patients with existing cardiovascular disease or risk factors should use etodolac with caution and under the guidance of a healthcare professional.

  11. Renal Effects: Long-term use of NSAIDs like etodolac may impair kidney function and increase the risk of kidney damage, particularly in susceptible individuals. Patients with pre-existing kidney disease or dehydration are at higher risk and should be closely monitored while taking etodolac.

  12. Drug Interactions: Etodolac may interact with other medications, including blood thinners, corticosteroids, diuretics, and certain antidepressants. Patients should inform their healthcare provider about all medications they are taking to avoid potential interactions.

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Data Contradictions β€” Limits of Certainity

Impacted of etodolac,(prescription) On Probiotics

Rank Probiotic Impact

Bacteria Impacted by etodolac,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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Taxonomy Rank Effect Citations Notation
Parabacteroides genus Decreases 👪 Source Study BMI, fat percent,blood pressure
unclassified Robinsoniella no rank Decreases ⚗️ Source Study
unclassified Fusobacterium no rank Decreases ⚗️ Source Study
unclassified Negativicoccus no rank Decreases ⚗️ Source Study
Eggerthellales order Decreases ⚗️ Source Study
Anaerofustis stercorihominis species Decreases ⚗️ Source Study
Asaccharospora irregularis species Decreases ⚗️ Source Study
Negativicoccus sp. S5-A15 species Decreases ⚗️ Source Study
Paraprevotella clara species Decreases ⚗️ Source Study
Slackia sp. NATTS species Decreases ⚗️ Source Study
Pseudoflavonifractor capillosus species Decreases ⚗️ Source Study
[Collinsella] massiliensis species Decreases ⚗️ Source Study
Parvibacter caecicola species Decreases ⚗️ Source Study
Parabacteroides distasonis species Decreases 📓 Source Study
Coriobacterineae suborder Decreases ⚗️ Source Study
Chlamydiae/Verrucomicrobia group superphylum Decreases ⚗️ Source Study

Impact of etodolac,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
ADHD 0 0
Age-Related Macular Degeneration and Glaucoma 0 0
Allergic Rhinitis (Hay Fever) 0 0
Allergy to milk products 0 0
Alopecia (Hair Loss) 0 0
Ankylosing spondylitis 0 0
Anorexia Nervosa 0 0
Atrial fibrillation 0 0 0
Autism 0 0 0
Bipolar Disorder 0 0
Carcinoma 0 0 0
Celiac Disease 0 0
Chronic Fatigue Syndrome 0.1 0 0
Chronic Kidney Disease 0 0
Coagulation / Micro clot triggering bacteria 0 0
Colorectal Cancer 0 0
COVID-19 0 0
Crohn's Disease 0 0 0
Depression 0.4 0 0
Endometriosis 0 0
Epilepsy 0 0
Fibromyalgia 0 0
Functional constipation / chronic idiopathic constipation 0 0
gallstone disease (gsd) 0 0
Graves' disease 0 0
hyperglycemia 0 0
hypertension (High Blood Pressure 0 0
Hypoxia 0 0
Inflammatory Bowel Disease 0 0
Intracranial aneurysms 0 0
Irritable Bowel Syndrome 0 0
Liver Cirrhosis 0 0
Long COVID 0 0 0
ME/CFS without IBS 0.1 0 0
Metabolic Syndrome 0 0 0
Mood Disorders 0.4 0 0
Multiple Sclerosis 0 0.1 0
Obesity 0 0 0
obsessive-compulsive disorder 0 0
Parkinson's Disease 0 0
Polycystic ovary syndrome 0 0
Premenstrual dysphoric disorder 0 0
Psoriasis 0.1 -0.1
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 0 0
Schizophrenia 0 0
Sjögren syndrome 0 0 0
Stress / posttraumatic stress disorder 0 0
Systemic Lupus Erythematosus 0 0
Type 2 Diabetes 0 0 0
Ulcerative colitis 0 0

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