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Emergency Treatment of Anaphylaxis: Epinephrine is the first-line treatment for anaphylaxis, a severe and potentially life-threatening allergic reaction. It works rapidly to reverse symptoms such as hives, swelling, difficulty breathing, and low blood pressure, by constricting blood vessels and relaxing airway muscles.
Management of Asthma: Epinephrine can be used as a bronchodilator to relieve acute asthma symptoms by relaxing the muscles around the airways, thereby improving airflow and alleviating wheezing, shortness of breath, and coughing.
Cardiac Arrest: In cardiac arrest, epinephrine is administered as part of advanced cardiac life support (ACLS) protocols to stimulate the heart and increase cardiac output, thereby improving blood flow to vital organs until further interventions such as defibrillation can be performed.
Treatment of Bradycardia: Epinephrine is used to increase heart rate and blood pressure in patients with symptomatic bradycardia (abnormally slow heart rate) that is unresponsive to other measures.
Local Hemostasis: In minor surgical procedures and interventions, epinephrine is often added to local anesthetic solutions to prolong their effects and minimize bleeding by constricting blood vessels in the targeted area.
Nasal Congestion: Epinephrine may be used in nasal decongestant formulations to relieve nasal congestion by shrinking swollen nasal mucous membranes, although its use for this purpose is less common now due to the availability of safer alternatives.
Ophthalmic Use: In ophthalmology, epinephrine is sometimes added to eye drops to induce mydriasis (pupil dilation) during eye examinations or surgeries and to reduce intraocular pressure in conditions such as glaucoma.
Topical Hemostasis: Epinephrine-soaked sponges or swabs may be applied topically to control bleeding from small wounds or surgical sites.
| Rank | Probiotic | Impact |
|---|
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
| Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
|---|---|---|---|
| Abdominal Aortic Aneurysm | 0.6 | -0.6 | |
| Acne | 0.6 | 0.5 | 0.2 |
| ADHD | 2.5 | 2.8 | -0.12 |
| Age-Related Macular Degeneration and Glaucoma | 0.9 | 0.5 | 0.8 |
| Allergic Rhinitis (Hay Fever) | 0.6 | 1.4 | -1.33 |
| Allergies | 2.1 | 1.7 | 0.24 |
| Allergy to milk products | 2 | 1 | 1 |
| Alopecia (Hair Loss) | 1 | 0.6 | 0.67 |
| Alzheimer's disease | 3.1 | 4 | -0.29 |
| Amyotrophic lateral sclerosis (ALS) Motor Neuron | 2.1 | 2.5 | -0.19 |
| Ankylosing spondylitis | 1.8 | 3.9 | -1.17 |
| Anorexia Nervosa | 1.2 | 3.7 | -2.08 |
| Antiphospholipid syndrome (APS) | 0.3 | 0.3 | |
| Asthma | 2.1 | 1.9 | 0.11 |
| Atherosclerosis | 0.8 | 1.7 | -1.13 |
| Atrial fibrillation | 4 | 0.9 | 3.44 |
| Autism | 5.8 | 5.5 | 0.05 |
| benign prostatic hyperplasia | 0.2 | -0.2 | |
| Bipolar Disorder | 2.1 | 3.4 | -0.62 |
| Brain Trauma | 2 | 0.3 | 5.67 |
| Breast Cancer | 0.2 | 0.2 | 0 |
| Carcinoma | 1.6 | 2.5 | -0.56 |
| Celiac Disease | 2.7 | 1.8 | 0.5 |
| Cerebral Palsy | 1 | 1.3 | -0.3 |
| Chronic Fatigue Syndrome | 3.2 | 1.5 | 1.13 |
| Chronic Kidney Disease | 0.8 | 2.4 | -2 |
| Chronic Lyme | 0.3 | -0.3 | |
| Chronic Obstructive Pulmonary Disease (COPD) | 0.9 | 1.2 | -0.33 |
| Chronic Urticaria (Hives) | 2 | 0.2 | 9 |
| Coagulation / Micro clot triggering bacteria | 2.5 | -2.5 | |
| Colorectal Cancer | 1.7 | 1.2 | 0.42 |
| Constipation | 2.3 | 0.8 | 1.87 |
| Coronary artery disease | 0.9 | 2.4 | -1.67 |
| COVID-19 | 4.9 | 4.8 | 0.02 |
| Crohn's Disease | 6.1 | 6.2 | -0.02 |
| cystic fibrosis | 0.6 | 0.3 | 1 |
| deep vein thrombosis | 1.5 | -1.5 | |
| Depression | 5.5 | 5.2 | 0.06 |
| Dermatomyositis | 0.3 | 0.3 | |
| Eczema | 1 | -1 | |
| Endometriosis | 0.9 | 2.9 | -2.22 |
| Eosinophilic Esophagitis | 0.2 | 0.2 | |
| Epilepsy | 2.9 | 2.7 | 0.07 |
| erectile dysfunction | 0.7 | 0.7 | |
| Fibromyalgia | 2.7 | 1.8 | 0.5 |
| Functional constipation / chronic idiopathic constipation | 4.8 | 3 | 0.6 |
| gallstone disease (gsd) | 1.8 | 1 | 0.8 |
| Gastroesophageal reflux disease (Gerd) including Barrett's esophagus | 0.4 | 0.4 | 0 |
| Generalized anxiety disorder | 0.3 | 0.2 | 0.5 |
| Glioblastoma | 1 | 0.7 | 0.43 |
| Gout | 0.6 | 1.3 | -1.17 |
| Graves' disease | 0.2 | 3.1 | -14.5 |
| Halitosis | 0.9 | -0.9 | |
| Hashimoto's thyroiditis | 2.7 | 0.2 | 12.5 |
| Hemorrhoidal disease, Hemorrhoids, Piles | 0.2 | 0.2 | |
| Hidradenitis Suppurativa | 0.8 | -0.8 | |
| Histamine Issues,Mast Cell Issue, DAO Insufficiency | 0.7 | 0.7 | 0 |
| hypercholesterolemia (High Cholesterol) | 0.6 | 0.4 | 0.5 |
| hyperglycemia | 1.5 | 1.1 | 0.36 |
| Hyperlipidemia (High Blood Fats) | 0.6 | 0.6 | |
| hypersomnia | 0.5 | 0.2 | 1.5 |
| hypertension (High Blood Pressure | 1.8 | 3.6 | -1 |
| Hypothyroidism | 0.8 | 2 | -1.5 |
| Hypoxia | 0.4 | 0.4 | 0 |
| IgA nephropathy (IgAN) | 1.5 | 0.8 | 0.88 |
| Inflammatory Bowel Disease | 2.4 | 3.1 | -0.29 |
| Insomnia | 1.3 | 2.9 | -1.23 |
| Intelligence | 3.7 | 0.2 | 17.5 |
| Intracranial aneurysms | 1.7 | 0.4 | 3.25 |
| Irritable Bowel Syndrome | 3.1 | 2.5 | 0.24 |
| Liver Cirrhosis | 3 | 3 | 0 |
| Long COVID | 6.9 | 5.7 | 0.21 |
| Low bone mineral density | 0.3 | 1.4 | -3.67 |
| Lung Cancer | 0.9 | 1.1 | -0.22 |
| ME/CFS with IBS | 1 | 0.3 | 2.33 |
| ME/CFS without IBS | 0.6 | 0.3 | 1 |
| Metabolic Syndrome | 5.3 | 5.7 | -0.08 |
| Mood Disorders | 6.3 | 6.9 | -0.1 |
| multiple chemical sensitivity [MCS] | 0.4 | 0.2 | 1 |
| Multiple Sclerosis | 4.5 | 2.3 | 0.96 |
| Multiple system atrophy (MSA) | 0.3 | 0.4 | -0.33 |
| myasthenia gravis | 0.2 | 0.2 | |
| Neuropathy (all types) | 0.7 | 0.7 | |
| neuropsychiatric disorders (PANDAS, PANS) | 1.2 | 0.5 | 1.4 |
| Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | 3.3 | 3.9 | -0.18 |
| Obesity | 6 | 4.9 | 0.22 |
| obsessive-compulsive disorder | 2.8 | 2.8 | 0 |
| Osteoarthritis | 1.5 | 0.5 | 2 |
| Osteoporosis | 1 | 1.8 | -0.8 |
| Parkinson's Disease | 3.8 | 4.4 | -0.16 |
| Polycystic ovary syndrome | 1.5 | 2.8 | -0.87 |
| Postural orthostatic tachycardia syndrome | 0.2 | 0.2 | 0 |
| Premenstrual dysphoric disorder | 0.8 | 0.2 | 3 |
| primary biliary cholangitis | 0.7 | 0.7 | |
| Psoriasis | 2.5 | 1.7 | 0.47 |
| rheumatoid arthritis (RA),Spondyloarthritis (SpA) | 4.5 | 4.5 | 0 |
| Rosacea | 0.2 | 0.3 | -0.5 |
| Schizophrenia | 2.9 | 3.1 | -0.07 |
| scoliosis | 1.1 | 0.2 | 4.5 |
| sensorineural hearing loss | 0.5 | -0.5 | |
| Sjögren syndrome | 2.8 | 3.7 | -0.32 |
| Sleep Apnea | 1.4 | 0.8 | 0.75 |
| Small Intestinal Bacterial Overgrowth (SIBO) | 0.4 | -0.4 | |
| Stress / posttraumatic stress disorder | 2.3 | 1.9 | 0.21 |
| Systemic Lupus Erythematosus | 3.1 | 3.9 | -0.26 |
| Tic Disorder | 2.4 | 1.5 | 0.6 |
| Tourette syndrome | 0.2 | -0.2 | |
| Type 1 Diabetes | 2.8 | 1.8 | 0.56 |
| Type 2 Diabetes | 5.3 | 4.3 | 0.23 |
| Ulcerative colitis | 5.2 | 2.6 | 1 |
| Unhealthy Ageing | 1.2 | 0.9 | 0.33 |
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