🍽️ procaine hydrochloride,(prescription)

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  1. Local Anesthesia: Procaine hydrochloride acts as a local anesthetic by blocking the transmission of nerve impulses, thereby inhibiting the sensation of pain in a specific area of the body where it is applied or injected. It works by reversibly inhibiting the function of voltage-gated sodium channels in nerve cell membranes, preventing the generation and propagation of action potentials.

  2. Dental Procedures: Procaine hydrochloride is frequently used by dentists for local anesthesia during dental procedures, such as tooth extractions, fillings, root canals, and gum surgeries. It is administered via injection into the soft tissues surrounding the treatment area to numb the nerves and alleviate pain.

  3. Minor Surgical Procedures: Procaine hydrochloride may also be used for local anesthesia during minor surgical procedures, dermatological procedures, and medical interventions that require pain control in a specific region of the body. It is commonly used in outpatient settings and medical offices for procedures such as skin biopsies, suturing of wounds, and removal of skin lesions.

  4. Onset and Duration of Action: The onset of action of procaine hydrochloride typically occurs within a few minutes after administration, with the peak effect reached within 5 to 10 minutes. The duration of anesthesia varies depending on factors such as the concentration of the procaine solution, the volume injected, and the vascularity of the tissues. Generally, the effects of procaine last for approximately 30 minutes to one hour.

  5. Adverse Effects: While procaine hydrochloride is generally considered safe when used appropriately, it may cause certain adverse effects, particularly if administered incorrectly or in excessive doses. Common side effects may include local reactions at the injection site, such as pain, swelling, bruising, and redness. In rare cases, allergic reactions, including anaphylaxis, may occur, especially in individuals with a history of hypersensitivity to local anesthetics.

  6. Precautions: Procaine hydrochloride should be used with caution in patients with a known allergy to local anesthetics, as well as those with certain medical conditions such as cardiovascular disease, epilepsy, or myasthenia gravis. Careful aspiration prior to injection and slow, incremental administration of the drug can help minimize the risk of inadvertent intravascular injection and systemic toxicity.

  7. Contraindications: Procaine hydrochloride is contraindicated in patients with a history of severe allergic reactions to local anesthetics, as well as those with certain medical conditions that may increase the risk of adverse effects or complications. It should not be used in regions of infection or inflammation, and caution should be exercised when administering it near major nerves or blood vessels.

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Data Contradictions β€” Limits of Certainity

Impacted of procaine hydrochloride,(prescription) On Probiotics

Rank Probiotic Impact
species Akkermansia muciniphila Reduces
species Lacticaseibacillus paracasei Reduces

Bacteria Impacted by procaine hydrochloride,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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Taxonomy Rank Effect Citations Notation
Lacticaseibacillus genus Decreases 👪 Source Study
Mediterraneibacter genus Decreases 👪 Source Study
Akkermansia genus Decreases 👪 Source Study
Lacrimispora genus Decreases 👪 Source Study
unclassified Robinsoniella no rank Decreases ⚗️ Source Study
unclassified Fusobacterium no rank Decreases ⚗️ Source Study
unclassified Negativicoccus no rank Decreases ⚗️ Source Study
Eggerthellales order Decreases ⚗️ Source Study
Lacticaseibacillus paracasei species Decreases 📓 Source Study
Anaerofustis stercorihominis species Decreases ⚗️ Source Study
Asaccharospora irregularis species Decreases ⚗️ Source Study
Negativicoccus sp. S5-A15 species Decreases ⚗️ Source Study
Paraprevotella clara species Decreases ⚗️ Source Study
Slackia sp. NATTS species Decreases ⚗️ Source Study
Pseudoflavonifractor capillosus species Decreases ⚗️ Source Study
[Collinsella] massiliensis species Decreases ⚗️ Source Study
[Ruminococcus] torques species Decreases 📓 Source Study
Parvibacter caecicola species Decreases ⚗️ Source Study
Akkermansia muciniphila species Decreases 📓 Source Study
Lacrimispora saccharolytica species Decreases 📓 Source Study
Coriobacterineae suborder Decreases ⚗️ Source Study
Lacticaseibacillus paracasei subsp. paracasei subspecies Decreases 👶 Source Study
Chlamydiae/Verrucomicrobia group superphylum Decreases ⚗️ Source Study

Impact of procaine hydrochloride,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Allergies 0 0
Alzheimer's disease 0 0.1 0
Amyotrophic lateral sclerosis (ALS) Motor Neuron 0.1 0 0
Asthma 0.1 -0.1
Atherosclerosis 0 0
Autism 0.2 0.1 1
Celiac Disease 0 0
Cerebral Palsy 0 0
Chronic Fatigue Syndrome 0.4 0.4
Chronic Kidney Disease 0.1 0.1
Chronic Urticaria (Hives) 0 0
COVID-19 0 0.1 0
Crohn's Disease 0 0 0
Depression 0.9 0.6 0.5
Epilepsy 0 0.1 0
Functional constipation / chronic idiopathic constipation 0.1 -0.1
Hashimoto's thyroiditis 0.1 0.1
Histamine Issues,Mast Cell Issue, DAO Insufficiency 0.1 -0.1
hypercholesterolemia (High Cholesterol) 0 0
hyperglycemia 0.1 -0.1
Hyperlipidemia (High Blood Fats) 0 0
hypertension (High Blood Pressure 0 0 0
Hypoxia 0 0
Inflammatory Bowel Disease 0.1 -0.1
Irritable Bowel Syndrome 0 0 0
Liver Cirrhosis 0 0 0
Long COVID 0 0
Lung Cancer 0 0
ME/CFS without IBS 0.1 0.1
Metabolic Syndrome 0 0.1 0
Mood Disorders 1 0.6 0.67
multiple chemical sensitivity [MCS] 0 0
Multiple Sclerosis 0.1 0.1
Multiple system atrophy (MSA) 0.1 0.1
Neuropathy (all types) 0 0
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 0 0
Obesity 0.1 0.6 -5
obsessive-compulsive disorder 0.2 -0.2
Osteoporosis 0 0
Parkinson's Disease 0.1 0.1
Polycystic ovary syndrome 0 0
Psoriasis 0 0 0
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 0 0
Rosacea 0.1 0.1
Schizophrenia 0 0
Stress / posttraumatic stress disorder 0 0 0
Tourette syndrome 0 0
Type 2 Diabetes 0 0.1 0
Ulcerative colitis 0.3 0.1 2
Unhealthy Ageing 0.1 0 0

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