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Antioxidant Activity: Esculin exhibits antioxidant properties, which means it can neutralize harmful free radicals in the body. This antioxidant activity may help protect cells from damage caused by oxidative stress and reduce the risk of chronic diseases such as cardiovascular disease and cancer.
Anti-inflammatory Effects: Esculin has been investigated for its anti-inflammatory effects. It may help reduce inflammation in the body, which is associated with various conditions such as arthritis, inflammatory bowel disease, and other inflammatory disorders.
Antibacterial Activity: Esculin possesses antibacterial properties, making it potentially useful in fighting bacterial infections. It has been studied for its activity against a range of bacteria, including both Gram-positive and Gram-negative bacteria.
Anticoagulant Properties: Esculin has been found to have anticoagulant or blood-thinning effects. This property may be beneficial in preventing blood clot formation and reducing the risk of conditions such as deep vein thrombosis, pulmonary embolism, and stroke.
Skin Health: Some topical formulations containing esculin are used in skincare products for their potential benefits in improving skin health. Esculin may help reduce skin inflammation, lighten hyperpigmentation, and improve the overall appearance of the skin.
Ophthalmic Use: Esculin has been used in ophthalmic preparations, such as eye drops, for its potential effects on eye health. It may have anti-inflammatory and antioxidant effects that could benefit conditions such as eye irritation, inflammation, and oxidative damage.
| Rank | Probiotic | Impact |
|---|---|---|
| species | Enterococcus durans | Increases |
| species | Enterococcus faecalis | Increases |
| species | Enterococcus faecium | Increases |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
| Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
|---|---|---|---|
| Allergic Rhinitis (Hay Fever) | 0.4 | -0.4 | |
| Allergies | 0.4 | 0.4 | |
| Allergy to milk products | 0.6 | 0.6 | |
| Alzheimer's disease | 0.6 | -0.6 | |
| Atrial fibrillation | 0.4 | -0.4 | |
| Autism | 1 | 1 | |
| Bipolar Disorder | 1 | 1 | |
| Cerebral Palsy | 0.4 | -0.4 | |
| Chronic Fatigue Syndrome | 0.4 | 0.4 | 0 |
| COVID-19 | 0.8 | 1.4 | -0.75 |
| Crohn's Disease | 0.4 | -0.4 | |
| cystic fibrosis | 0.2 | 0.4 | -1 |
| Depression | 1 | -1 | |
| Eczema | 0.4 | -0.4 | |
| Epilepsy | 0.4 | -0.4 | |
| Generalized anxiety disorder | 0.6 | -0.6 | |
| Histamine Issues,Mast Cell Issue, DAO Insufficiency | 0.8 | -0.8 | |
| hypercholesterolemia (High Cholesterol) | 0.8 | 0.8 | |
| hypertension (High Blood Pressure | 0.4 | 0.4 | 0 |
| IgA nephropathy (IgAN) | 0.4 | 0.4 | |
| Inflammatory Bowel Disease | 0.8 | -0.8 | |
| Irritable Bowel Syndrome | 0.4 | 0.4 | 0 |
| Liver Cirrhosis | 0.4 | 0.4 | 0 |
| Long COVID | 1 | -1 | |
| ME/CFS with IBS | 0.4 | 0.4 | 0 |
| ME/CFS without IBS | 0.4 | 0.4 | 0 |
| Metabolic Syndrome | 0.8 | 0.8 | 0 |
| Mood Disorders | 1 | 1 | 0 |
| obsessive-compulsive disorder | 0.4 | -0.4 | |
| Parkinson's Disease | 0.6 | -0.6 | |
| Psoriasis | 0.4 | -0.4 | |
| rheumatoid arthritis (RA),Spondyloarthritis (SpA) | 1 | 0.4 | 1.5 |
| Schizophrenia | 1 | 0.4 | 1.5 |
| Small Intestinal Bacterial Overgrowth (SIBO) | 0.4 | 1.2 | -2 |
| Stress / posttraumatic stress disorder | 0.4 | -0.4 | |
| Systemic Lupus Erythematosus | 1 | -1 | |
| Type 2 Diabetes | 0.4 | -0.4 | |
| Ulcerative colitis | 0.4 | 1 | -1.5 |
| Unhealthy Ageing | 0.4 | -0.4 |
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