🍽️ phenacetin,(prescription)

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  1. Antihistamine Effect: Pheniramine maleate works by blocking the effects of histamine, a substance produced by the body during allergic reactions. By inhibiting histamine receptors, it reduces the symptoms of allergic rhinitis (hay fever), allergic conjunctivitis, and other allergic conditions.

  2. Relief of Allergic Symptoms: Pheniramine maleate can alleviate symptoms such as sneezing, itching (including itching of the eyes, nose, and throat), watery eyes, and runny nose caused by allergic reactions to pollen, dust, animal dander, and other allergens.

  3. Sedation: Pheniramine maleate has sedative effects and may cause drowsiness or dizziness, particularly in some individuals. As a result, it is often included in nighttime or nighttime formulations of cold and allergy medications to help promote sleep.

  4. Treatment of Cough: Pheniramine maleate is sometimes included in cough syrups or cold medications to help relieve cough associated with allergic rhinitis or upper respiratory tract infections. It may help reduce the frequency and severity of coughing episodes.

  5. Combination Formulations: Pheniramine maleate is commonly found in combination products with other medications, such as decongestants (e.g., pseudoephedrine), analgesics (e.g., paracetamol), and/or antipyretics (e.g., acetaminophen), to provide comprehensive relief from cold and allergy symptoms.

  6. Side Effects: Common side effects of pheniramine maleate may include drowsiness, dry mouth, blurred vision, constipation, and urinary retention. These side effects are usually mild and transient but may be more pronounced in some individuals.

  7. Central Nervous System Effects: Pheniramine maleate can penetrate the blood-brain barrier, leading to central nervous system effects such as sedation, drowsiness, and impaired cognitive function. Patients should avoid activities that require mental alertness, such as driving or operating heavy machinery, until they know how the medication affects them.

  8. Interaction with Alcohol: Concurrent use of pheniramine maleate with alcohol or other central nervous system depressants may enhance sedative effects and increase the risk of drowsiness, dizziness, and impaired coordination. Patients should avoid alcohol while taking pheniramine maleate.

  9. Precautions: Pheniramine maleate should be used with caution in elderly patients, patients with liver or kidney impairment, and those with urinary retention or narrow-angle glaucoma. Dosage adjustments may be necessary in these populations to minimize the risk of adverse effects.

  10. Pregnancy and Lactation: The safety of pheniramine maleate use during pregnancy and breastfeeding has not been well established. Pregnant or breastfeeding women should consult their healthcare provider before using this medication.

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βš—οΈ Compensation for antibiotic usage

Data Contradictions β€” Limits of Certainity

Impacted of phenacetin,(prescription) On Probiotics

Rank Probiotic Impact
species Akkermansia muciniphila Reduces
species Bifidobacterium adolescentis Reduces
species Bifidobacterium longum Reduces
subspecies Bifidobacterium longum subsp. infantis Reduces
subspecies Bifidobacterium longum subsp. longum Reduces

Bacteria Impacted by phenacetin,(prescription)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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Taxonomy Rank Effect Citations Notation
Akkermansiaceae family Decreases 👪 Source Study
Thomasclavelia genus Decreases 👪 Source Study
Roseburia genus Decreases 👪 Source Study
Collinsella genus Decreases 👪 Source Study proinflammatory
Lacrimispora genus Decreases 👪 Source Study
Blautia genus Decreases 👪 Source Study
Parabacteroides genus Decreases 👪 Source Study BMI, fat percent,blood pressure
Bacteroides genus Decreases 👪 Source Study
Odoribacter genus Decreases 👪 Source Study
Eggerthella genus Decreases 👪 Source Study
Mediterraneibacter genus Decreases 👪 Source Study
Bifidobacterium genus Decreases 👪 Source Study
Veillonella genus Decreases 👪 Source Study
Clostridium genus Decreases 👪 Source Study Pathogen
Akkermansia genus Decreases 📓 Source Study
Enterocloster genus Decreases 👪 Source Study
Clostridioides genus Decreases 👪 Source Study
Lachnospira genus Decreases 👪 Source Study
unclassified Robinsoniella no rank Decreases ⚗️ Source Study
unclassified Fusobacterium no rank Decreases ⚗️ Source Study
unclassified Negativicoccus no rank Decreases ⚗️ Source Study
environmental samples no rank Decreases 👶 Source Study
unclassified Akkermansia no rank Decreases 👶 Source Study
Eggerthellales order Decreases ⚗️ Source Study
Thomasclavelia ramosa species Decreases 📓 Source Study
Roseburia hominis species Decreases 📓 Source Study
Collinsella aerofaciens species Decreases 📓 Source Study
Lacrimispora saccharolytica species Decreases 📓 Source Study
Bacteroides xylanisolvens species Decreases 📓 Source Study
Blautia obeum species Decreases 📓 Source Study
Parabacteroides distasonis species Decreases 📓 Source Study
Bacteroides caccae species Decreases 📓 Source Study
Odoribacter splanchnicus species Decreases 📓 Source Study
[Ruminococcus] gnavus species Decreases 📓 Source Study
Eggerthella lenta species Decreases 📓 Source Study
Bifidobacterium adolescentis species Decreases 📓 Source Study
[Ruminococcus] torques species Decreases 📓 Source Study
Bifidobacterium longum species Decreases 📓 Source Study
Veillonella parvula species Decreases 📓 Source Study
Clostridium perfringens species Decreases 📓 Source Study Food poisoning, gas gangrene
Anaerofustis stercorihominis species Decreases ⚗️ Source Study
Asaccharospora irregularis species Decreases ⚗️ Source Study
Negativicoccus sp. S5-A15 species Decreases ⚗️ Source Study
Paraprevotella clara species Decreases ⚗️ Source Study
Slackia sp. NATTS species Decreases ⚗️ Source Study
Pseudoflavonifractor capillosus species Decreases ⚗️ Source Study
[Collinsella] massiliensis species Decreases ⚗️ Source Study
Parvibacter caecicola species Decreases ⚗️ Source Study
Akkermansia muciniphila species Decreases 📓 Source Study
Enterocloster bolteae species Decreases 📓 Source Study
Clostridioides difficile species Decreases 📓 Source Study Colitis
Lachnospira eligens species Decreases 📓 Source Study
Akkermansia glycaniphila species Decreases 👶 Source Study
Coriobacterineae suborder Decreases ⚗️ Source Study
Bifidobacterium longum subsp. infantis subspecies Decreases 👶 Source Study
Bifidobacterium longum subsp. longum subspecies Decreases 👶 Source Study
Bifidobacterium longum subsp. suillum subspecies Decreases 👶 Source Study
Chlamydiae/Verrucomicrobia group superphylum Decreases ⚗️ Source Study

Impact of phenacetin,(prescription) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Acne 0.1 -0.1
ADHD 1.5 0.2 6.5
Age-Related Macular Degeneration and Glaucoma 0.4 0.3 0.33
Allergic Rhinitis (Hay Fever) 1 0.6 0.67
Allergies 1.8 0.5 2.6
Allergy to milk products 0.4 0.4 0
Alopecia (Hair Loss) 1.2 1.2
Alzheimer's disease 1 2.4 -1.4
Amyotrophic lateral sclerosis (ALS) Motor Neuron 0.5 0.1 4
Ankylosing spondylitis 1.5 0.6 1.5
Anorexia Nervosa 0.3 1.1 -2.67
Asthma 0.6 0.8 -0.33
Atherosclerosis 0.5 0.9 -0.8
Atrial fibrillation 1.1 0.7 0.57
Autism 3.2 2.3 0.39
Barrett esophagus cancer 0.1 0.1
Biofilm 0.3 0.3
Bipolar Disorder 0.6 0.7 -0.17
Brain Trauma 0.5 0.7 -0.4
Cancer (General) 0.2 1.2 -5
Carcinoma 1.7 1.5 0.13
Celiac Disease 0.6 1.6 -1.67
Cerebral Palsy 0.4 1 -1.5
Chronic Fatigue Syndrome 2 2.1 -0.05
Chronic Kidney Disease 1.3 0.8 0.63
Chronic Lyme 0.7 -0.7
Chronic Obstructive Pulmonary Disease (COPD) 0.1 0.4 -3
Chronic Urticaria (Hives) 0.2 0.1 1
Coagulation / Micro clot triggering bacteria 0.3 0.7 -1.33
Colorectal Cancer 1.2 0.5 1.4
Constipation 0.3 0.7 -1.33
Coronary artery disease 0.7 0.4 0.75
COVID-19 4.6 4.3 0.07
Crohn's Disease 2.7 2 0.35
cystic fibrosis 0.8 -0.8
deep vein thrombosis 0.4 -0.4
Depression 4.2 3.1 0.35
Dermatomyositis 0.1 -0.1
Eczema 0.4 0.2 1
Endometriosis 1 0.3 2.33
Eosinophilic Esophagitis 0.1 -0.1
Epilepsy 1.1 1.1 0
Fibromyalgia 1.9 0.5 2.8
Functional constipation / chronic idiopathic constipation 1 1.6 -0.6
gallstone disease (gsd) 0.8 0.5 0.6
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 0.1 0.6 -5
Generalized anxiety disorder 0.6 0.7 -0.17
giant cell arteritis 0.1 -0.1
Graves' disease 1 1.1 -0.1
Halitosis 0.4 0.4
Hashimoto's thyroiditis 1.4 0.4 2.5
Hidradenitis Suppurativa 0.1 -0.1
High Histamine/low DAO 0.7 0.1 6
hypercholesterolemia (High Cholesterol) 0.3 0.1 2
hyperglycemia 0 1.1 0
Hyperlipidemia (High Blood Fats) 0.5 0.4 0.25
hypersomnia 0.3 -0.3
hypertension (High Blood Pressure 1.1 2.6 -1.36
Hypothyroidism 0.6 -0.6
Hypoxia 0.6 0.6
IgA nephropathy (IgAN) 0.6 -0.6
Inflammatory Bowel Disease 2.1 2.9 -0.38
Insomnia 0.6 0.7 -0.17
Intelligence 0.1 0.1
Intracranial aneurysms 0.9 0.4 1.25
Irritable Bowel Syndrome 1.6 1.3 0.23
Liver Cirrhosis 1.8 1.1 0.64
Long COVID 3.5 3.8 -0.09
Low bone mineral density 0.4 -0.4
Lung Cancer 0.5 0.4 0.25
Mast Cell Issues / mastitis 0.1 -0.1
ME/CFS with IBS 0.2 1 -4
ME/CFS without IBS 1 1 0
Menopause 0.5 0.5
Metabolic Syndrome 3.8 3.2 0.19
Mood Disorders 5.1 3.2 0.59
multiple chemical sensitivity [MCS] 0.2 0.3 -0.5
Multiple Sclerosis 1.6 1.9 -0.19
Multiple system atrophy (MSA) 0.9 0.4 1.25
neuropathic pain 1.2 -1.2
Neuropathy (all types) 0.4 0.4
neuropsychiatric disorders (PANDAS, PANS) 0.2 0.2
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 0.8 2.1 -1.63
NonCeliac Gluten Sensitivity 0.1 -0.1
Obesity 4.9 1.7 1.88
obsessive-compulsive disorder 1.3 1.6 -0.23
Osteoarthritis 1.5 1.5
Osteoporosis 0.6 0.7 -0.17
pancreatic cancer 0.2 0.2
Parkinson's Disease 1.1 0.8 0.38
Polycystic ovary syndrome 1 0.8 0.25
Postural orthostatic tachycardia syndrome 0.1 0.1 0
Premenstrual dysphoric disorder 0.8 0.3 1.67
primary biliary cholangitis 0.4 -0.4
Psoriasis 1.4 1.6 -0.14
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 3 1.5 1
Rosacea 0.4 0.5 -0.25
Schizophrenia 2.5 0.9 1.78
scoliosis 0 0
Sjögren syndrome 1.1 1.3 -0.18
Sleep Apnea 0.4 1.1 -1.75
Slow gastric motility / Gastroparesis 0.4 0.1 3
Small Intestinal Bacterial Overgrowth (SIBO) 0.2 -0.2
Stress / posttraumatic stress disorder 1.2 1.6 -0.33
Systemic Lupus Erythematosus 1.6 1 0.6
Tic Disorder 0.2 0.5 -1.5
Tourette syndrome 0 0.3 0
Type 1 Diabetes 0.7 0.8 -0.14
Type 2 Diabetes 3.6 1.7 1.12
Ulcerative colitis 0.8 1.5 -0.88
Unhealthy Ageing 1.3 0.7 0.86

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