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Pain Relief: Fosfosal is used to alleviate mild to moderate pain, including headache, toothache, menstrual cramps, muscle aches, and joint pain associated with conditions such as osteoarthritis and rheumatoid arthritis.
Anti-inflammatory Action: Like other NSAIDs, fosfosal exerts anti-inflammatory effects by inhibiting the production of prostaglandins, which are substances involved in inflammation. This can help reduce inflammation, swelling, and redness associated with various conditions, including arthritis and soft tissue injuries.
Fever Reduction: Fosfosal can also lower fever by acting on the hypothalamus, the part of the brain responsible for regulating body temperature. It helps to reduce fever by inhibiting the production of prostaglandins in the brain.
Musculoskeletal Disorders: Fosfosal may be prescribed for musculoskeletal disorders such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and gout, to help relieve pain and inflammation associated with these conditions.
Dental Pain: It is sometimes used for the relief of dental pain, including toothache and post-dental procedure pain.
Menstrual Pain: Fosfosal can help alleviate menstrual pain (dysmenorrhea) by reducing prostaglandin levels, which are known to contribute to uterine contractions and pain during menstruation.
Postoperative Pain: It may be used as part of multimodal analgesia to manage postoperative pain following surgical procedures.
Administration: Fosfosal is usually taken orally in the form of tablets or capsules. The dosage and frequency of administration depend on the patient's age, medical condition, and response to treatment. It is typically taken with food or a glass of milk to reduce the risk of gastrointestinal irritation.
Adverse Effects: Common side effects of fosfosal may include gastrointestinal discomfort, such as dyspepsia (indigestion), nausea, vomiting, abdominal pain, and diarrhea. It may also cause dizziness, headache, and allergic reactions in some individuals. Long-term use or high doses of fosfosal may increase the risk of gastrointestinal ulcers and bleeding.
Contraindications and Precautions: Fosfosal is contraindicated in patients with a history of hypersensitivity to salicylates or NSAIDs, peptic ulcer disease, severe renal impairment, bleeding disorders, and asthma exacerbated by aspirin or other NSAIDs. It should be used with caution in elderly patients, those with renal or hepatic impairment, and individuals with a history of gastrointestinal bleeding or ulcers.
Rank | Probiotic | Impact |
---|---|---|
species | Lacticaseibacillus paracasei | Reduces |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
---|---|---|---|
ADHD | 0.8 | 0.8 | |
Allergic Rhinitis (Hay Fever) | 0 | 0 | |
Allergies | 0.4 | 0.6 | -0.5 |
Allergy to milk products | 0.3 | 0.3 | |
Alopecia (Hair Loss) | 0.2 | 0.2 | |
Alzheimer's disease | 1.7 | 0.6 | 1.83 |
Amyotrophic lateral sclerosis (ALS) Motor Neuron | 0.5 | 0.3 | 0.67 |
Ankylosing spondylitis | 0.2 | 1 | -4 |
Anorexia Nervosa | 0.6 | -0.6 | |
Asthma | 0 | 0 | |
Atherosclerosis | 1 | 1 | |
Atrial fibrillation | 0.6 | 0 | 0 |
Autism | 1.2 | 1.1 | 0.09 |
Barrett esophagus cancer | 0.5 | 0.5 | |
Biofilm | 0.9 | 0.9 | |
Bipolar Disorder | 0.3 | 0.3 | 0 |
Brain Trauma | 0.2 | 0 | 0 |
Cancer (General) | 0.4 | -0.4 | |
Carcinoma | 0.5 | 0.5 | 0 |
Celiac Disease | 0 | 0.6 | 0 |
Cerebral Palsy | 0.3 | -0.3 | |
Chronic Fatigue Syndrome | 1.7 | 0 | 0 |
Chronic Kidney Disease | 0 | 0.5 | 0 |
Chronic Lyme | 0 | 0 | |
Chronic Obstructive Pulmonary Disease (COPD) | 0.5 | 0.3 | 0.67 |
Chronic Urticaria (Hives) | 0 | 0 | |
Coagulation / Micro clot triggering bacteria | 0.3 | -0.3 | |
Colorectal Cancer | 1.7 | 0.2 | 7.5 |
Constipation | 0.3 | 0.3 | |
Coronary artery disease | 0.5 | 0.5 | |
COVID-19 | 1.2 | 1.7 | -0.42 |
Crohn's Disease | 1.9 | 1.8 | 0.06 |
cystic fibrosis | 0 | 0 | |
deep vein thrombosis | 0.3 | -0.3 | |
Depression | 1.3 | 1.4 | -0.08 |
Endometriosis | 0 | 0.6 | 0 |
Eosinophilic Esophagitis | 0.5 | 0.5 | |
Epilepsy | 0.7 | 0 | 0 |
Fibromyalgia | 0 | 0 | |
Functional constipation / chronic idiopathic constipation | 0.6 | 0 | 0 |
gallstone disease (gsd) | 0.3 | 0.5 | -0.67 |
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus | 0.5 | 0.5 | |
Generalized anxiety disorder | 0.5 | 0 | 0 |
Graves' disease | 0.2 | 0.2 | 0 |
Halitosis | 0.5 | 0.5 | |
Hashimoto's thyroiditis | 0 | 0 | 0 |
Hidradenitis Suppurativa | 0.5 | 0.5 | |
High Histamine/low DAO | 0.3 | -0.3 | |
hyperglycemia | 0 | 0 | |
Hyperlipidemia (High Blood Fats) | 0.2 | 0.2 | 0 |
hypertension (High Blood Pressure | 0.5 | 0 | 0 |
Hypoxia | 0 | 0 | |
IgA nephropathy (IgAN) | 0.6 | -0.6 | |
Inflammatory Bowel Disease | 0.2 | 1.6 | -7 |
Insomnia | 0 | 0.3 | 0 |
Intelligence | 0 | 0 | |
Intracranial aneurysms | 0.3 | 0.2 | 0.5 |
Irritable Bowel Syndrome | 0.3 | 0.3 | 0 |
Liver Cirrhosis | 0.8 | 0.3 | 1.67 |
Long COVID | 1.1 | 2.8 | -1.55 |
Low bone mineral density | 0.3 | -0.3 | |
Lung Cancer | 0.3 | -0.3 | |
Mast Cell Issues / mastitis | 0.3 | -0.3 | |
ME/CFS with IBS | 0.1 | 0 | 0 |
ME/CFS without IBS | 0 | 0 | |
Menopause | 0 | 0 | |
Metabolic Syndrome | 1.4 | 0.8 | 0.75 |
Mood Disorders | 1.8 | 1.4 | 0.29 |
Multiple Sclerosis | 0.7 | 0.9 | -0.29 |
Multiple system atrophy (MSA) | 0.3 | -0.3 | |
neuropathic pain | 0.3 | -0.3 | |
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | 0.2 | 0.6 | -2 |
NonCeliac Gluten Sensitivity | 0.2 | 0 | 0 |
Obesity | 0.9 | 1.4 | -0.56 |
obsessive-compulsive disorder | 0.9 | 0 | 0 |
Osteoarthritis | 0 | 0.3 | 0 |
Osteoporosis | 0.3 | 0 | 0 |
Parkinson's Disease | 0.7 | 1 | -0.43 |
Polycystic ovary syndrome | 0.3 | 0.6 | -1 |
Premenstrual dysphoric disorder | 0.2 | 0.2 | |
primary biliary cholangitis | 0.2 | -0.2 | |
Psoriasis | 0.7 | 0 | 0 |
rheumatoid arthritis (RA),Spondyloarthritis (SpA) | 2.2 | 0.7 | 2.14 |
Rosacea | 0.3 | 0.3 | |
Schizophrenia | 0.8 | 0.3 | 1.67 |
scoliosis | 0.8 | -0.8 | |
Sjögren syndrome | 0 | 0 | 0 |
Sleep Apnea | 0.7 | 0 | 0 |
Slow gastric motility / Gastroparesis | 0.3 | 0.3 | |
Small Intestinal Bacterial Overgrowth (SIBO) | 0.5 | 0.5 | |
Stress / posttraumatic stress disorder | 0.5 | 0.2 | 1.5 |
Systemic Lupus Erythematosus | 0.5 | 0.6 | -0.2 |
Tic Disorder | 0.3 | 0.2 | 0.5 |
Tourette syndrome | 0 | 0 | |
Type 1 Diabetes | 0.4 | 0.3 | 0.33 |
Type 2 Diabetes | 1.4 | 0.8 | 0.75 |
Ulcerative colitis | 0.2 | 0.1 | 1 |
Unhealthy Ageing | 1.6 | 1.6 | |
Vitiligo | 0.6 | 0.6 |
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