🍽️ propantheline bromide,(prescription) [Can cause cognitive issues]

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  1. Reduced Gastric Secretions: Propantheline bromide inhibits gastric acid secretion, which can help alleviate symptoms associated with peptic ulcers and other gastrointestinal conditions.

  2. Relief of Smooth Muscle Spasms: Propantheline bromide has antispasmodic effects on smooth muscles, particularly in the gastrointestinal tract. By reducing muscle spasms, it can help relieve abdominal pain, cramping, and discomfort associated with conditions like IBS.

  3. Decreased Motility: By slowing down gastrointestinal motility, propantheline bromide can help regulate bowel movements and reduce symptoms such as diarrhea.

  4. Blurred Vision: Propantheline bromide, like other anticholinergic medications, can cause side effects related to its inhibition of acetylcholine activity throughout the body. One common side effect is blurred vision, which may occur due to its effects on the muscles controlling the pupil's size.

  5. Dry Mouth: Anticholinergic medications like propantheline bromide can reduce saliva production, leading to dry mouth and increased thirst.

  6. Urinary Retention: Propantheline bromide may exacerbate urinary retention, particularly in individuals with pre-existing urinary issues or prostatic hypertrophy. This effect occurs due to its anticholinergic action on the bladder muscles, which can impair voiding.

  7. Constipation: In some individuals, propantheline bromide can lead to constipation as a result of its effects on gastrointestinal motility. This side effect may be more pronounced in patients prone to constipation or those taking other medications that slow bowel movements.

  8. Cognitive Issues: Long-term use of propantheline bromide, especially in older adults, has been associated with cognitive impairment and an increased risk of developing dementia. This risk is primarily attributed to its anticholinergic properties, which can interfere with cognitive function and memory.

  9. Heat Intolerance: Anticholinergic medications like propantheline bromide can impair the body's ability to regulate temperature, leading to decreased sweating and increased susceptibility to heat-related illnesses.

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βš—οΈ Compensation for antibiotic usage

Data Contradictions β€” Limits of Certainity

Impacted of propantheline bromide,(prescription) [Can cause cognitive issues] On Probiotics

Rank Probiotic Impact
species Akkermansia muciniphila Reduces
species Bifidobacterium adolescentis Reduces
species Bifidobacterium longum Reduces
species Escherichia coli Reduces
species Lacticaseibacillus paracasei Reduces
subspecies Bifidobacterium longum subsp. infantis Reduces
subspecies Bifidobacterium longum subsp. longum Reduces

Bacteria Impacted by propantheline bromide,(prescription) [Can cause cognitive issues]

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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Taxonomy Rank Effect Citations Notation
Roseburia genus Decreases 👪 Source Study
Eggerthella genus Decreases 👪 Source Study
Collinsella genus Decreases 👪 Source Study proinflammatory
Odoribacter genus Decreases 👪 Source Study
Veillonella genus Decreases 👪 Source Study
Dorea genus Decreases 👪 Source Study
Bifidobacterium genus Decreases 👪 Source Study
Bacteroides genus Decreases 👪 Source Study
Clostridioides genus Decreases 👪 Source Study
Agathobacter genus Decreases 👪 Source Study
Thomasclavelia genus Decreases 👪 Source Study
Blautia genus Decreases 👪 Source Study
Fusobacterium genus Decreases 👪 Source Study Periodontal disease, Lemierre syndrome, skin ulcers
Mediterraneibacter genus Decreases 👪 Source Study
Lachnospira genus Decreases 👪 Source Study
Phocaeicola genus Decreases 👪 Source Study
Ruminococcus genus Decreases 👪 Source Study
Escherichia genus Decreases 👪 Source Study
Parabacteroides genus Decreases 👪 Source Study BMI, fat percent,blood pressure
Lacticaseibacillus genus Decreases 👪 Source Study
Enterocloster genus Decreases 👪 Source Study
Clostridium genus Decreases 👪 Source Study Pathogen
Akkermansia genus Decreases 👪 Source Study
unclassified Robinsoniella no rank Decreases ⚗️ Source Study
unclassified Fusobacterium no rank Decreases ⚗️ Source Study
unclassified Negativicoccus no rank Decreases ⚗️ Source Study
Escherichia coli O80:H26 no rank Decreases 👶 Source Study
Eggerthellales order Decreases ⚗️ Source Study
Escherichia coli O145 serogroup Decreases 👶 Source Study
Escherichia coli O157 serogroup Decreases 👶 Source Study
Escherichia coli O26 serogroup Decreases 👶 Source Study
Escherichia coli O43 serogroup Decreases 👶 Source Study
Escherichia coli O1:H42 serotype Decreases 👶 Source Study
Escherichia coli O104:H4 serotype Decreases 👶 Source Study
Escherichia coli O121:H19 serotype Decreases 👶 Source Study
Escherichia coli O127:H6 serotype Decreases 👶 Source Study
Escherichia coli O139:H28 serotype Decreases 👶 Source Study
Escherichia coli O157:H7 serotype Decreases 👶 Source Study bloody diarrhea
Escherichia coli O44:H18 serotype Decreases 👶 Source Study
Escherichia coli O55:H7 serotype Decreases 👶 Source Study
Escherichia coli O6:H16 serotype Decreases 👶 Source Study
Escherichia coli O7:K1 serotype Decreases 👶 Source Study
Roseburia hominis species Decreases 📓 Source Study
Eggerthella lenta species Decreases 📓 Source Study
Bifidobacterium longum species Decreases 📓 Source Study
Collinsella aerofaciens species Decreases 📓 Source Study
Odoribacter splanchnicus species Decreases 📓 Source Study
Veillonella parvula species Decreases 📓 Source Study
Dorea formicigenerans species Decreases 📓 Source Study
Bacteroides xylanisolvens species Decreases 📓 Source Study
Bacteroides ovatus species Decreases 📓 Source Study
[Ruminococcus] torques species Decreases 📓 Source Study
Clostridioides difficile species Decreases 📓 Source Study Colitis
Agathobacter rectalis species Decreases 📓 Source Study
Bifidobacterium adolescentis species Decreases 📓 Source Study
Thomasclavelia ramosa species Decreases 📓 Source Study
Bacteroides fragilis species Decreases 📓 Source Study H02076 Bacteroides infection
Blautia obeum species Decreases 📓 Source Study
Bacteroides caccae species Decreases 📓 Source Study
Fusobacterium nucleatum species Decreases 📓 Source Study Infectious bacteria
Lachnospira eligens species Decreases 📓 Source Study
Phocaeicola vulgatus species Decreases 📓 Source Study
Ruminococcus bromii species Decreases 📓 Source Study
Escherichia coli species Decreases 📓 Source Study Diarrheal disease in children and travelers, Foodborne diarrhea outbreaks, hemorrhagic colitis, hemolytic-uremic syndrome
Parabacteroides distasonis species Decreases 📓 Source Study
Anaerofustis stercorihominis species Decreases ⚗️ Source Study
Asaccharospora irregularis species Decreases ⚗️ Source Study
Lacticaseibacillus paracasei species Decreases 📓 Source Study
Negativicoccus sp. S5-A15 species Decreases ⚗️ Source Study
Paraprevotella clara species Decreases ⚗️ Source Study
Slackia sp. NATTS species Decreases ⚗️ Source Study
Pseudoflavonifractor capillosus species Decreases ⚗️ Source Study
[Collinsella] massiliensis species Decreases ⚗️ Source Study
Parvibacter caecicola species Decreases ⚗️ Source Study
Enterocloster bolteae species Decreases 📓 Source Study
Clostridium perfringens species Decreases 📓 Source Study Food poisoning, gas gangrene
[Ruminococcus] gnavus species Decreases 📓 Source Study
Akkermansia muciniphila species Decreases 📓 Source Study
Coriobacterineae suborder Decreases ⚗️ Source Study
Bifidobacterium longum subsp. infantis subspecies Decreases 👶 Source Study
Bifidobacterium longum subsp. longum subspecies Decreases 👶 Source Study
Bifidobacterium longum subsp. suillum subspecies Decreases 👶 Source Study
Fusobacterium nucleatum subsp. nucleatum subspecies Decreases 👶 Source Study
Lacticaseibacillus paracasei subsp. paracasei subspecies Decreases 👶 Source Study
Chlamydiae/Verrucomicrobia group superphylum Decreases ⚗️ Source Study

Impact of propantheline bromide,(prescription) [Can cause cognitive issues] on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Acne 0.3 -0.3
ADHD 3.5 0.4 7.75
Age-Related Macular Degeneration and Glaucoma 0.8 0.1 7
Allergic Rhinitis (Hay Fever) 0.5 1.5 -2
Allergies 4 0.8 4
Allergy to milk products 0.6 0.5 0.2
Alopecia (Hair Loss) 1.1 1.1
Alzheimer's disease 2.3 4.3 -0.87
Amyotrophic lateral sclerosis (ALS) Motor Neuron 1.8 0.4 3.5
Ankylosing spondylitis 2.1 0.7 2
Anorexia Nervosa 0.1 1.4 -13
Antiphospholipid syndrome (APS) 0.2 0.2
Asthma 1.1 0.8 0.38
Atherosclerosis 0.9 1.2 -0.33
Atrial fibrillation 2 0.8 1.5
Autism 5.3 5 0.06
Barrett esophagus cancer 0.5 0.5
benign prostatic hyperplasia 0.1 0.1
Bipolar Disorder 0.6 1.3 -1.17
Brain Trauma 0.7 0.7 0
Cancer (General) 0.4 2 -4
Carcinoma 2.5 2 0.25
Celiac Disease 1.5 3 -1
Cerebral Palsy 0.7 1 -0.43
Chronic Fatigue Syndrome 4 4 0
Chronic Kidney Disease 1.4 1.4 0
Chronic Lyme 0.7 -0.7
Chronic Obstructive Pulmonary Disease (COPD) 0.5 0.6 -0.2
Chronic Urticaria (Hives) 0.7 0.4 0.75
Coagulation / Micro clot triggering bacteria 0.4 0.8 -1
Colorectal Cancer 2.8 0.9 2.11
Constipation 0.8 0.6 0.33
Coronary artery disease 0.7 0.5 0.4
COVID-19 7.4 7.5 -0.01
Crohn's Disease 4.5 3.9 0.15
cystic fibrosis 0.3 1 -2.33
deep vein thrombosis 0.3 0.6 -1
Depression 6 4.6 0.3
Dermatomyositis 0.3 -0.3
Eczema 0.5 0.7 -0.4
Endometriosis 1.5 1 0.5
Eosinophilic Esophagitis 0.2 0.4 -1
Epilepsy 1.7 0.9 0.89
Fibromyalgia 1.5 0.6 1.5
Functional constipation / chronic idiopathic constipation 3.3 2.3 0.43
gallstone disease (gsd) 1.3 0.9 0.44
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 1.2 0.4 2
Generalized anxiety disorder 0.7 1.3 -0.86
giant cell arteritis 0 0
Graves' disease 1 1.4 -0.4
Halitosis 0.8 0.8
Hashimoto's thyroiditis 2.1 0.5 3.2
Hidradenitis Suppurativa 0.2 0.4 -1
Histamine Issues 2.6 0.5 4.2
hypercholesterolemia (High Cholesterol) 0.4 0 0
hyperglycemia 0.1 0.9 -8
Hyperlipidemia (High Blood Fats) 0.7 0.4 0.75
hypersomnia 0.2 -0.2
hypertension (High Blood Pressure 1.3 3.7 -1.85
Hypothyroidism 0.9 -0.9
Hypoxia 0.4 0.4
IgA nephropathy (IgAN) 1.3 -1.3
Inflammatory Bowel Disease 2.4 4.5 -0.88
Insomnia 0.4 0.9 -1.25
Intelligence 0 0
Intracranial aneurysms 0.7 0.4 0.75
Irritable Bowel Syndrome 2.2 2.5 -0.14
Liver Cirrhosis 2.8 1.9 0.47
Long COVID 4 5.8 -0.45
Low bone mineral density 0.6 -0.6
Lung Cancer 0.4 0.7 -0.75
Mast Cell Issues / mastitis 0.1 0.4 -3
ME/CFS with IBS 0.1 1.6 -15
ME/CFS without IBS 1.3 1.8 -0.38
Menopause 1.8 1.8
Metabolic Syndrome 4.9 5.4 -0.1
Mood Disorders 7.3 5 0.46
multiple chemical sensitivity [MCS] 0.4 0.2 1
Multiple Sclerosis 3.2 2.3 0.39
Multiple system atrophy (MSA) 1 0.6 0.67
neuropathic pain 1.6 -1.6
Neuropathy (all types) 0.2 0.1 1
neuropsychiatric disorders (PANDAS, PANS) 0.6 0.6
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 1 3.3 -2.3
NonCeliac Gluten Sensitivity 0.3 -0.3
Obesity 6.3 2.4 1.63
obsessive-compulsive disorder 3.5 2.3 0.52
Osteoarthritis 0.8 0.1 7
Osteoporosis 1.3 0.5 1.6
pancreatic cancer 0.4 0.4
Parkinson's Disease 1.4 2.1 -0.5
Polycystic ovary syndrome 1.1 1.4 -0.27
Postural orthostatic tachycardia syndrome 0 0.3 0
Premenstrual dysphoric disorder 0.8 0.1 7
primary biliary cholangitis 0.4 0.4 0
Psoriasis 3 1.1 1.73
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 3.9 3 0.3
Rosacea 1 0.5 1
Schizophrenia 4.1 1.1 2.73
scoliosis 0.4 -0.4
Sjögren syndrome 1.8 1.8 0
Sleep Apnea 0.8 1.3 -0.63
Small Intestinal Bacterial Overgrowth (SIBO) 0.4 0.8 -1
Stress / posttraumatic stress disorder 1.9 2.2 -0.16
Systemic Lupus Erythematosus 2.3 1.6 0.44
Tic Disorder 0.8 1 -0.25
Tourette syndrome 0 0.3 0
Type 1 Diabetes 2.3 1.3 0.77
Type 2 Diabetes 5.1 3.1 0.65
Ulcerative colitis 1.5 2.5 -0.67
Unhealthy Ageing 3.3 1.5 1.2

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