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Obesity: Processed foods are often high in calories, unhealthy fats (such as trans fats and saturated fats), sugar, and refined carbohydrates. Consuming these foods regularly can contribute to weight gain and obesity, as they tend to be energy-dense but nutrient-poor. Additionally, processed foods may lead to overeating due to their palatability and lack of satiety.
Type 2 Diabetes: Highly processed foods, especially those containing added sugars and refined carbohydrates, can cause rapid spikes in blood sugar levels. Over time, this can lead to insulin resistance, impaired glucose tolerance, and an increased risk of developing type 2 diabetes. Processed foods may also contribute to inflammation, which is closely linked to insulin resistance and diabetes.
Cardiovascular Disease (CVD): Processed foods often contain high levels of sodium, unhealthy fats, and added sugars, which can negatively impact heart health. Diets high in processed foods have been associated with an increased risk of hypertension (high blood pressure), dyslipidemia (abnormal blood lipid levels), and atherosclerosis (hardening of the arteries), all of which are risk factors for cardiovascular disease, heart attack, and stroke.
Digestive Disorders: Highly processed foods are typically low in dietary fiber, which is important for digestive health and regular bowel movements. Inadequate fiber intake can increase the risk of constipation, diverticulosis, and other digestive disorders. Additionally, processed foods may contain additives, preservatives, and artificial ingredients that can irritate the gastrointestinal tract and contribute to digestive discomfort or symptoms like bloating and gas.
Cancer: Some studies suggest that diets high in processed foods may increase the risk of certain types of cancer, including colorectal cancer. Processed meats, in particular, have been classified as carcinogenic (cancer-causing) by the International Agency for Research on Cancer (IARC). The high levels of sodium, nitrates, nitrites, and other additives in processed meats are thought to contribute to this increased cancer risk.
Mental Health: Poor dietary patterns, including high consumption of processed foods, have been linked to an increased risk of mental health disorders such as depression and anxiety. Processed foods may disrupt neurotransmitter function, promote inflammation in the brain, and negatively affect mood regulation. Additionally, diets rich in highly processed foods are often lacking in essential nutrients like omega-3 fatty acids, vitamins, and minerals, which are important for brain health.
Nutrient Deficiencies: Highly processed foods are typically low in essential nutrients such as vitamins, minerals, antioxidants, and dietary fiber. Relying heavily on processed foods in the diet can lead to nutrient deficiencies and imbalances, which may increase the risk of various health problems, including fatigue, weakened immune function, and impaired wound healing.
Chronic Inflammation: Many processed foods contain inflammatory ingredients such as refined sugars, refined grains, unhealthy fats, and food additives. Chronic inflammation is a key underlying factor in the development of many chronic diseases, including autoimmune conditions, metabolic syndrome, and cardiovascular disease.
| Rank | Probiotic | Impact |
|---|
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
| Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
|---|---|---|---|
| Abdominal Aortic Aneurysm | 0.2 | -0.2 | |
| Acne | 0.5 | -0.5 | |
| ADHD | 0.2 | 1.4 | -6 |
| Allergic Rhinitis (Hay Fever) | 0.5 | 0.5 | |
| Allergies | 1 | 0.5 | 1 |
| Allergy to milk products | 0.9 | 0.9 | |
| Alzheimer's disease | 1.1 | 1.4 | -0.27 |
| Amyotrophic lateral sclerosis (ALS) Motor Neuron | 1.1 | 0.2 | 4.5 |
| Ankylosing spondylitis | 0.5 | 0.2 | 1.5 |
| Anorexia Nervosa | 0.5 | 1.2 | -1.4 |
| Asthma | 0.5 | 1.5 | -2 |
| Atherosclerosis | 0.7 | 0.5 | 0.4 |
| Atrial fibrillation | 0.2 | 0.5 | -1.5 |
| Autism | 1.4 | 2.1 | -0.5 |
| Bipolar Disorder | 1.9 | 1.4 | 0.36 |
| Brain Trauma | 1 | -1 | |
| Breast Cancer | 0.2 | -0.2 | |
| Carcinoma | 0.4 | 0.6 | -0.5 |
| Celiac Disease | 1.8 | -1.8 | |
| Cerebral Palsy | 0.7 | -0.7 | |
| Chronic Fatigue Syndrome | 0.5 | 1 | -1 |
| Chronic Kidney Disease | 0.2 | 0.7 | -2.5 |
| Chronic Obstructive Pulmonary Disease (COPD) | 0.2 | 0.2 | |
| Chronic Urticaria (Hives) | 1 | -1 | |
| Coagulation / Micro clot triggering bacteria | 0.4 | -0.4 | |
| Colorectal Cancer | 0.2 | 0.5 | -1.5 |
| Constipation | 0.5 | -0.5 | |
| Coronary artery disease | 0.4 | 0.2 | 1 |
| COVID-19 | 0.9 | 1.7 | -0.89 |
| Crohn's Disease | 2 | 2.5 | -0.25 |
| cystic fibrosis | 0.5 | -0.5 | |
| deep vein thrombosis | 0.4 | -0.4 | |
| Depression | 1.3 | 1.4 | -0.08 |
| Eczema | 1 | 1 | |
| Endometriosis | 1.2 | 0.2 | 5 |
| Epilepsy | 1.2 | 0.7 | 0.71 |
| Fibromyalgia | 0.7 | 1 | -0.43 |
| Functional constipation / chronic idiopathic constipation | 1.4 | 0.5 | 1.8 |
| gallstone disease (gsd) | 0.6 | 0.5 | 0.2 |
| Glioblastoma | 0.5 | -0.5 | |
| Gout | 0.5 | -0.5 | |
| Hashimoto's thyroiditis | 0.2 | 0.5 | -1.5 |
| Hemorrhoidal disease, Hemorrhoids, Piles | 0.2 | 0.2 | |
| hypercholesterolemia (High Cholesterol) | 0.5 | -0.5 | |
| hyperglycemia | 0.5 | 0.5 | 0 |
| hypersomnia | 0.2 | 0.2 | 0 |
| hypertension (High Blood Pressure | 0.7 | 1 | -0.43 |
| Hypothyroidism | 0.2 | 0.7 | -2.5 |
| IgA nephropathy (IgAN) | 0.5 | 0.2 | 1.5 |
| Inflammatory Bowel Disease | 0.7 | 1.4 | -1 |
| Insomnia | 0.5 | -0.5 | |
| Intelligence | 0.2 | 0.7 | -2.5 |
| Intracranial aneurysms | 0.8 | 0.5 | 0.6 |
| Irritable Bowel Syndrome | 0.7 | 1.4 | -1 |
| Liver Cirrhosis | 0.9 | 0.9 | 0 |
| Long COVID | 2.4 | 2.1 | 0.14 |
| Low bone mineral density | 0.2 | -0.2 | |
| Lung Cancer | 0.2 | 0.7 | -2.5 |
| ME/CFS with IBS | 1 | -1 | |
| ME/CFS without IBS | 0.3 | 0.3 | |
| Metabolic Syndrome | 1.9 | 1.9 | 0 |
| Mood Disorders | 2.7 | 1.4 | 0.93 |
| multiple chemical sensitivity [MCS] | 0.5 | -0.5 | |
| Multiple Sclerosis | 0.6 | 1.9 | -2.17 |
| Multiple system atrophy (MSA) | 0.2 | -0.2 | |
| neuropsychiatric disorders (PANDAS, PANS) | 1 | -1 | |
| Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | 0.5 | 1.9 | -2.8 |
| Obesity | 1.8 | 2.7 | -0.5 |
| obsessive-compulsive disorder | 0.7 | 1.2 | -0.71 |
| Osteoarthritis | 1.4 | -1.4 | |
| Osteoporosis | 0.7 | 0.7 | 0 |
| Parkinson's Disease | 0.9 | 1.7 | -0.89 |
| Polycystic ovary syndrome | 0.7 | 0.5 | 0.4 |
| Psoriasis | 0.7 | 0.7 | |
| rheumatoid arthritis (RA),Spondyloarthritis (SpA) | 1.1 | 1 | 0.1 |
| Rosacea | 0.2 | 0.2 | |
| Schizophrenia | 1.1 | 0.7 | 0.57 |
| scoliosis | 0.2 | -0.2 | |
| Sjögren syndrome | 1 | 1.7 | -0.7 |
| Sleep Apnea | 0.4 | 0.5 | -0.25 |
| Stress / posttraumatic stress disorder | 1.7 | -1.7 | |
| Systemic Lupus Erythematosus | 0.2 | 1.4 | -6 |
| Tic Disorder | 0.7 | 0.7 | |
| Type 1 Diabetes | 0.2 | 1 | -4 |
| Type 2 Diabetes | 1.9 | 1.9 | 0 |
| Ulcerative colitis | 1.1 | 1.7 | -0.55 |
| Unhealthy Ageing | 0.7 | -0.7 |
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