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🍽️ ß-2,6-polyfructose {Levan}

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  1. Prebiotic Effects: Levan has been studied for its potential prebiotic properties. As a fermentable fiber, it can serve as a substrate for beneficial bacteria in the gut, promoting their growth and activity. By stimulating the growth of beneficial gut bacteria, levan may help improve gut health and support the balance of the gut microbiota. A healthy gut microbiota is associated with various health benefits, including improved digestion, immune function, and overall well-being.

  2. Blood Sugar Regulation: Some research suggests that certain types of dietary fibers, including levan, may have beneficial effects on blood sugar levels. By slowing down the absorption of glucose from the digestive tract into the bloodstream, fibers like levan can help regulate blood sugar levels and prevent rapid spikes and crashes in blood glucose. This effect may be particularly beneficial for individuals with diabetes or those at risk of developing diabetes.

  3. Digestive Health: Like other dietary fibers, levan can add bulk to stool and promote bowel regularity. By increasing fecal bulk and softening stool, levan may help prevent constipation and promote overall digestive health. Additionally, the fermentation of levan by gut bacteria produces short-chain fatty acids (SCFAs), which provide energy for colon cells and help maintain a healthy gut environment.

  4. Weight Management: Dietary fibers like levan can contribute to feelings of fullness and satiety when consumed as part of a meal or snack. By increasing the bulk of food in the digestive tract and delaying gastric emptying, levan may help reduce hunger and calorie intake, which could support weight management efforts.

  5. Immune Function: While direct evidence is limited, some research suggests that certain dietary fibers, including levan, may have immunomodulatory effects. By influencing the composition and activity of the gut microbiota, dietary fibers can indirectly impact immune function. A healthy gut microbiota is essential for maintaining a balanced immune response and protecting against infections and inflammatory conditions.

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Data Contradictions β€” Limits of Certainity

Impacted of ß-2,6-polyfructose {Levan} On Probiotics

Rank Probiotic Impact
species Bacteroides uniformis Increases
species Escherichia coli Increases
species Faecalibacterium prausnitzii Increases
species Streptococcus thermophilus Increases

Bacteria Impacted by ß-2,6-polyfructose {Levan}

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

πŸ§™?

Taxonomy Rank Effect Citations Notation
Bacteroidaceae family Increases 👪 Source Study
Enterobacteriaceae family Increases 👪 Source Study
Oscillospiraceae family Increases 👪 Source Study
Streptococcaceae family Increases 👪 Source Study
Bacteroides genus Increases 📓 Source Study
Escherichia genus Increases 📓 Source Study
Faecalibacterium genus Increases 📓 Source Study
Streptococcus genus Increases 📓 Source Study
environmental samples no rank Increases 👶 Source Study
environmental samples no rank Increases 👶 Source Study
environmental samples no rank Increases 👶 Source Study
unclassified Bacteroides no rank Increases 👶 Source Study
unclassified Escherichia no rank Increases 👶 Source Study
unclassified Faecalibacterium no rank Increases 👶 Source Study
unclassified Streptococcus no rank Increases 👶 Source Study
Bacteroides bouchesdurhonensis QSV445 Increases 👶 Source Study
Bacteroides acidifaciens species Increases 👶 Source Study
Bacteroides caccae species Increases 👶 Source Study
Bacteroides caecigallinarum species Increases 👶 Source Study
Bacteroides caecimuris species Increases 👶 Source Study
Bacteroides cellulosilyticus species Increases 👶 Source Study
Bacteroides clarus species Increases 👶 Source Study
Bacteroides congonensis species Increases 👶 Source Study
Bacteroides coprosuis species Increases 👶 Source Study
Bacteroides cutis species Increases 👶 Source Study
Bacteroides denticanum species Increases 👶 Source Study
Bacteroides difficilis species Increases 👶 Source Study
Bacteroides eggerthii species Increases 👶 Source Study
Bacteroides faecalis species Increases 👶 Source Study
Bacteroides faecichinchillae species Increases 👶 Source Study
Bacteroides faecis species Increases 👶 Source Study
Bacteroides faecium species Increases 👶 Source Study
Bacteroides finegoldii species Increases 👶 Source Study
Bacteroides fluxus species Increases 👶 Source Study
Bacteroides fragilis species Increases 👶 Source Study H02076 Bacteroides infection
Bacteroides galacturonicus species Increases 👶 Source Study
Bacteroides gallinaceum species Increases 👶 Source Study
Bacteroides gallinarum species Increases 👶 Source Study
Bacteroides graminisolvens species Increases 👶 Source Study
Bacteroides helcogenes species Increases 👶 Source Study
Bacteroides heparinolyticus species Increases 👶 Source Study
Bacteroides humanifaecis species Increases 👶 Source Study
Bacteroides ihuae species Increases 👶 Source Study
Bacteroides ilei species Increases 👶 Source Study
Bacteroides intestinalis species Increases 👶 Source Study
Bacteroides koreensis species Increases 👶 Source Study
Bacteroides kribbi species Increases 👶 Source Study
Bacteroides luhongzhouii species Increases 👶 Source Study
Bacteroides luti species Increases 👶 Source Study
Bacteroides mediterraneensis species Increases 👶 Source Study
Bacteroides ndongoniae species Increases 👶 Source Study
Bacteroides nordii species Increases 👶 Source Study
Bacteroides oleiciplenus species Increases 👶 Source Study
Bacteroides ovatus species Increases 👶 Source Study
Bacteroides parvus species Increases 👶 Source Study
Bacteroides propionicifaciens species Increases 👶 Source Study
Bacteroides propionicigenes species Increases 👶 Source Study
Bacteroides pyogenes species Increases 👶 Source Study
Bacteroides reticulotermitis species Increases 👶 Source Study
Bacteroides rhinocerotis species Increases 👶 Source Study
Bacteroides rodentium species Increases 👶 Source Study
Bacteroides salyersiae species Increases 👶 Source Study
Bacteroides stercorirosoris species Increases 👶 Source Study
Bacteroides stercoris species Increases 👶 Source Study
Bacteroides thetaiotaomicron species Increases 👶 Source Study
Bacteroides timonensis species Increases 👶 Source Study
Bacteroides uniformis species Increases 👶 Source Study Infectious bacteria
Bacteroides xylanisolvens species Increases 👶 Source Study
Bacteroides zhangwenhongii species Increases 👶 Source Study
Bacteroides zoogleoformans species Increases 👶 Source Study
Candidatus Bacteroides intestinigallinarum species Increases 👶 Source Study
Escherichia albertii species Increases 👶 Source Study
Escherichia coli species Increases 👶 Source Study Diarrheal disease in children and travelers, Foodborne diarrhea outbreaks, hemorrhagic colitis, hemolytic-uremic syndrome
Escherichia fergusonii species Increases 👶 Source Study
Escherichia marmotae species Increases 👶 Source Study
Escherichia ruysiae species Increases 👶 Source Study
Faecalibacterium duncaniae species Increases 👶 Source Study
Faecalibacterium hattorii species Increases 👶 Source Study
Faecalibacterium hominis (ex Afrizal et al. 2022) species Increases 👶 Source Study
Faecalibacterium longum species Increases 👶 Source Study
Faecalibacterium prausnitzii species Increases 👶 Source Study
Streptococcus acidominimus species Increases 👶 Source Study
Streptococcus agalactiae species Increases 👶 Source Study Postpartum infection, neonatal sepsis
Streptococcus alactolyticus species Increases 👶 Source Study
Streptococcus australis species Increases 👶 Source Study
Streptococcus azizii species Increases 👶 Source Study
Streptococcus caballi species Increases 👶 Source Study
Streptococcus canis species Increases 👶 Source Study
Streptococcus castoreus species Increases 👶 Source Study
Streptococcus chenjunshii species Increases 👶 Source Study
Streptococcus chosunense species Increases 👶 Source Study
Streptococcus criceti species Increases 👶 Source Study
Streptococcus cristatus species Increases 👶 Source Study
Streptococcus cuniculipharyngis species Increases 👶 Source Study
Streptococcus danieliae species Increases 👶 Source Study
Streptococcus dentapri species Increases 👶 Source Study
Streptococcus dentasini species Increases 👶 Source Study
Streptococcus dentirousetti species Increases 👶 Source Study
Streptococcus devriesei species Increases 👶 Source Study
Streptococcus didelphis species Increases 👶 Source Study
Streptococcus downei species Increases 👶 Source Study
Streptococcus entericus species Increases 👶 Source Study
Streptococcus equinus species Increases 👶 Source Study
Streptococcus ferus species Increases 👶 Source Study
Streptococcus fryi species Increases 👶 Source Study
Streptococcus gallinaceus species Increases 👶 Source Study
Streptococcus gallolyticus species Increases 👶 Source Study
Streptococcus gordonii species Increases 👶 Source Study
Streptococcus gwangjuense species Increases 👶 Source Study
Streptococcus halichoeri species Increases 👶 Source Study
Streptococcus halotolerans species Increases 👶 Source Study
Streptococcus henryi species Increases 👶 Source Study
Streptococcus himalayensis species Increases 👶 Source Study
Streptococcus hongkongensis species Increases 👶 Source Study
Streptococcus hyointestinalis species Increases 👶 Source Study
Streptococcus hyovaginalis species Increases 👶 Source Study
Streptococcus ictaluri species Increases 👶 Source Study
Streptococcus ilei species Increases 👶 Source Study H01443 Viridans group streptococcal infection
Streptococcus infantarius species Increases 👶 Source Study
Streptococcus infantis species Increases 👶 Source Study
Streptococcus iniae species Increases 👶 Source Study
Streptococcus koreensis species Increases 👶 Source Study
Streptococcus lactarius species Increases 👶 Source Study
Streptococcus lutetiensis species Increases 👶 Source Study
Streptococcus macacae species Increases 👶 Source Study
Streptococcus macedonicus species Increases 👶 Source Study
Streptococcus marimammalium species Increases 👶 Source Study
Streptococcus marmotae species Increases 👶 Source Study
Streptococcus massiliensis species Increases 👶 Source Study
Streptococcus merionis species Increases 👶 Source Study
Streptococcus milleri species Increases 👶 Source Study
Streptococcus minor species Increases 👶 Source Study
Streptococcus mitis species Increases 👶 Source Study Infectious bacteria
Streptococcus mutans species Increases 👶 Source Study Tooth decay
Streptococcus oralis species Increases 👶 Source Study Infectious bacteria
Streptococcus orisasini species Increases 👶 Source Study
Streptococcus oriscaviae species Increases 👶 Source Study
Streptococcus orisratti species Increases 👶 Source Study
Streptococcus orisuis species Increases 👶 Source Study
Streptococcus ovis species Increases 👶 Source Study
Streptococcus panodentis species Increases 👶 Source Study
Streptococcus pantholopis species Increases 👶 Source Study
Streptococcus parasanguinis species Increases 👶 Source Study
Streptococcus parasuis species Increases 👶 Source Study
Streptococcus parauberis species Increases 👶 Source Study
Streptococcus pasteuri species Increases 👶 Source Study
Streptococcus pasteurianus species Increases 👶 Source Study
Streptococcus periodonticum species Increases 👶 Source Study
Streptococcus peroris species Increases 👶 Source Study
Streptococcus phocae species Increases 👶 Source Study
Streptococcus pluranimalium species Increases 👶 Source Study
Streptococcus plurextorum species Increases 👶 Source Study
Streptococcus pneumoniae species Increases 👶 Source Study Pneumonia, many other infections
Streptococcus porci species Increases 👶 Source Study
Streptococcus porcinus species Increases 👶 Source Study
Streptococcus porcorum species Increases 👶 Source Study
Streptococcus pseudopneumoniae species Increases 👶 Source Study Infectious bacteria
Streptococcus pseudoporcinus species Increases 👶 Source Study
Streptococcus pyogenes species Increases 👶 Source Study Pharyngitis, scarlet fever, impetigo, necrotizing fasciittis
Streptococcus ratti species Increases 👶 Source Study
Streptococcus respiraculi species Increases 👶 Source Study
Streptococcus rubneri species Increases 👶 Source Study
Streptococcus ruminantium species Increases 👶 Source Study
Streptococcus ruminicola species Increases 👶 Source Study
Streptococcus rupicaprae species Increases 👶 Source Study
Streptococcus salivarius species Increases 👶 Source Study Infectious bacteria
Streptococcus sanguinis species Increases 👶 Source Study
Streptococcus seminale species Increases 👶 Source Study
Streptococcus shenyangsis species Increases 👶 Source Study
Streptococcus sinensis species Increases 👶 Source Study
Streptococcus sobrinus species Increases 👶 Source Study
Streptococcus suis species Increases 👶 Source Study
Streptococcus symci species Increases 👶 Source Study
Streptococcus thermophilus species Increases 👶 Source Study
Streptococcus thoraltensis species Increases 👶 Source Study
Streptococcus timonensis species Increases 👶 Source Study
Streptococcus toyakuensis species Increases 👶 Source Study
Streptococcus troglodytae species Increases 👶 Source Study
Streptococcus troglodytidis species Increases 👶 Source Study
Streptococcus uberis species Increases 👶 Source Study
Streptococcus urinalis species Increases 👶 Source Study
Streptococcus vaginalis species Increases 👶 Source Study
Streptococcus vestibularis species Increases 👶 Source Study Infectious bacteria
Streptococcus viridans species Increases 👶 Source Study Subacute bacterial endocarditis
Streptococcus vulneris species Increases 👶 Source Study
Streptococcus xiaochunlingii species Increases 👶 Source Study
Streptococcus anginosus group species group Increases 👶 Source Study Pathogen
Streptococcus dysgalactiae group species group Increases 👶 Source Study

Impact of ß-2,6-polyfructose {Levan} on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
ADHD 0.6 0.4 0.5
Age-Related Macular Degeneration and Glaucoma 0.3 0.3
Allergic Rhinitis (Hay Fever) 1.2 -1.2
Allergies 0.8 1.6 -1
Allergy to milk products 1.2 1.7 -0.42
Alopecia (Hair Loss) 0.2 -0.2
Alzheimer's disease 1.7 2.6 -0.53
Amyotrophic lateral sclerosis (ALS) Motor Neuron 0.5 1.1 -1.2
Ankylosing spondylitis 0.9 2.2 -1.44
Anorexia Nervosa 1.2 0.6 1
Antiphospholipid syndrome (APS) 1 -1
Asthma 1.9 0.8 1.37
Atherosclerosis 0.6 0.6 0
Atrial fibrillation 1.8 1.2 0.5
Autism 3.1 3 0.03
Barrett esophagus cancer 0.6 0.6
benign prostatic hyperplasia 0.3 0.6 -1
Biofilm 1 -1
Bipolar Disorder 0.6 2 -2.33
Brain Trauma 1.4 0.3 3.67
Cancer (General) 0.4 0.4
Carcinoma 0.6 1.8 -2
Celiac Disease 1.8 1.7 0.06
Cerebral Palsy 1.2 0.6 1
Chronic Fatigue Syndrome 2 2.1 -0.05
Chronic Kidney Disease 1.2 -1.2
Chronic Lyme 0.6 0.3 1
Chronic Obstructive Pulmonary Disease (COPD) 0.3 1.2 -3
Chronic Urticaria (Hives) 1 1.4 -0.4
Coagulation / Micro clot triggering bacteria 0.9 1.8 -1
Colorectal Cancer 0.9 2.9 -2.22
Constipation 0.6 2.3 -2.83
COVID-19 4.4 5 -0.14
Crohn's Disease 1.6 2.9 -0.81
cystic fibrosis 1.5 0.8 0.88
deep vein thrombosis 0.9 1 -0.11
Depression 3.6 4.5 -0.25
Dermatomyositis 0.6 -0.6
Eczema 1 2 -1
Endometriosis 3.1 -3.1
Epilepsy 1.2 2.6 -1.17
erectile dysfunction 0.3 0.3
Fibromyalgia 1 1
Functional constipation / chronic idiopathic constipation 1.6 3.5 -1.19
gallstone disease (gsd) 0.6 0.6 0
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 0.6 0.6 0
Generalized anxiety disorder 0.6 0.8 -0.33
Glioblastoma 1.5 1.5
Gout 0.3 -0.3
Graves' disease 0.3 0.6 -1
Halitosis 0.6 0.6 0
Hashimoto's thyroiditis 1.2 0.6 1
Hidradenitis Suppurativa 0.6 -0.6
High Histamine/low DAO 0.6 0.5 0.2
hypercholesterolemia (High Cholesterol) 0.6 0.6
hyperglycemia 0.8 1.4 -0.75
hypersomnia 0.2 -0.2
hypertension (High Blood Pressure 2.5 1.8 0.39
Hypothyroidism 0.9 0.3 2
Hypoxia 0.6 -0.6
IgA nephropathy (IgAN) 0.8 0.3 1.67
Inflammatory Bowel Disease 1.6 3 -0.88
Insomnia 1.8 1.2 0.5
Intelligence 0.2 0.5 -1.5
Intracranial aneurysms 0.6 0.9 -0.5
Irritable Bowel Syndrome 1.8 2.7 -0.5
Liver Cirrhosis 1.8 2.7 -0.5
Long COVID 2.2 3.7 -0.68
Low bone mineral density 0.3 0.3
Lung Cancer 0.5 0.8 -0.6
Mast Cell Issues / mastitis 1.2 -1.2
ME/CFS with IBS 1.4 0.6 1.33
ME/CFS without IBS 0.6 0.6 0
Menopause 0.2 -0.2
Metabolic Syndrome 2.7 3.1 -0.15
Mood Disorders 3.9 4.9 -0.26
multiple chemical sensitivity [MCS] 0.2 1 -4
Multiple Sclerosis 2.4 1.5 0.6
Multiple system atrophy (MSA) 0.2 -0.2
myasthenia gravis 0.3 0.3
neuropathic pain 0.6 0.6
Neuropathy (all types) 0.6 0.6 0
neuropsychiatric disorders (PANDAS, PANS) 0.6 0.5 0.2
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 1.4 1.8 -0.29
NonCeliac Gluten Sensitivity 1.2 0.3 3
Obesity 1.9 2.5 -0.32
obsessive-compulsive disorder 1.2 3.5 -1.92
Osteoarthritis 0.8 1.8 -1.25
Osteoporosis 0.6 1.8 -2
pancreatic cancer 0.9 -0.9
Parkinson's Disease 3 3.9 -0.3
Polycystic ovary syndrome 0.6 1.7 -1.83
Postural orthostatic tachycardia syndrome 0.3 -0.3
primary biliary cholangitis 0.5 0.5
Psoriasis 0.6 2 -2.33
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 2.2 3.3 -0.5
Schizophrenia 0.9 1 -0.11
scoliosis 0.3 -0.3
Sjögren syndrome 1.6 2 -0.25
Sleep Apnea 1.2 0.6 1
Slow gastric motility / Gastroparesis 0.8 -0.8
Small Intestinal Bacterial Overgrowth (SIBO) 1.4 -1.4
Stress / posttraumatic stress disorder 1.6 1.1 0.45
Systemic Lupus Erythematosus 0.6 2.6 -3.33
Tic Disorder 0.2 0.9 -3.5
Tourette syndrome 0.9 0.9
Type 1 Diabetes 1.2 1.6 -0.33
Type 2 Diabetes 2.8 3.1 -0.11
Ulcerative colitis 2.1 2.3 -0.1
Unhealthy Ageing 0.6 1.7 -1.83
Vitiligo 0.2 0.8 -3

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