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Citizen Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.

SymptomImpactPredictor of Bacteria Shift
Age: 30-40Improves-1.92
Autism: Official DiagnosisWorsen3.23
Autonomic Manifestations: Cortisol disorders or irregularity Improves-1.7
Blood Type: A PositiveWorsen1.76
Blood Type: O PositiveWorsen3.13
Comorbid-Mouth: Bruxism - Jaw cleanching / Teeth grindingImproves-1.21
Comorbid-Mouth: Dry MouthImproves-1.76
Comorbid-Mouth: TMJ / Dysfunction of the temporomandibular joint syndromeWorsen3.01
Comorbid: Constipation and Explosions (not diarrohea)Worsen3.23
Comorbid: High AnxietyWorsen3.01
Comorbid: Inflammatory bowel disease Worsen1.64
Comorbid: Methylation issues (MTHFR)Worsen3.01
Comorbid: Snoring (NOT Sleep ApneaWorsen0.02
DePaul University Fatigue Questionnaire : Anxiety/tensionWorsen1.7
DePaul University Fatigue Questionnaire : Difficulty staying asleepImproves-1.92
DePaul University Fatigue Questionnaire : FatigueWorsen2.33
DePaul University Fatigue Questionnaire : Impaired Memory & concentrationWorsen1.76
DePaul University Fatigue Questionnaire : Unrefreshing Sleep, that is waking up feeling tired Worsen1.76
Gender: MaleImproves-1.21
Immune Manifestations: BloatingImproves-1.21
Infection: Human Herpesvirus 6 (HHV6)Improves-1.21
Infection: Parasite - OtherWorsen3.01
Joint: RednessImproves-1.92
Joint: TendernessWorsen3.01
Neurocognitive: Slowness of thoughtImproves-2.48
Neurocognitive: Unable to focus vision and/or attentionWorsen3.01
Neuroendocrine Manifestations: intolerance of extremes of heat and coldWorsen1.8
Neuroendocrine: Alcohol intoleranceImproves-1.21
Neuroendocrine: Feeling hot or cold for no reasonImproves-1.24
Neurological-Sleep: Chaotic diurnal sleep rhythms (Erratic Sleep)Improves-1.64
Neurological-Vision: photophobia (Light Sensitivity)Worsen3.01
Neurological: emotional overloadImproves-1.92
Neurological: Executive Decision Making (Difficulty making)Improves-1.21
Neurological: Short-term memory issuesImproves-1.56
Official Diagnosis: Allergic Rhinitis (Hay Fever)Worsen3.23
Official Diagnosis: Mast Cell DysfunctionWorsen3.01
Onset: GradualWorsen1.48
Post-exertional malaise: Difficulty reading after mild physical or mental activityWorsen3.01
Sleep: Problems falling asleepImproves-1.92

Published Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is according to the microbiome shifts reported in studies. Clinical studies may show different results

SymptomImpactPredictor of Bacteria Shift
Alzheimer's diseaseImproves-3.68
Amyotrophic lateral sclerosis (ALS) Motor NeuronWorsen3.52
Ankylosing spondylitisImproves-2.72
Anorexia NervosaImproves-3.01
Bipolar DisorderImproves-3.01
Brain TraumaImproves-3.54
Celiac DiseaseImproves-1.7
Cerebral PalsyImproves-3.01
Chronic Fatigue SyndromeImproves-3.38
Chronic Kidney DiseaseImproves-3.68
Chronic LymeImproves-3.01
Chronic Urticaria (Hives)Improves-1.63
Colorectal CancerWorsen1.62
Coronary artery disease Improves-2.77
Crohn's DiseaseImproves-3.01
Functional constipation / chronic idiopathic constipationImproves-4.26
gallstone disease (gsd)Improves-3.68
Hashimoto's thyroiditisWorsen3.27
High Blood PressureImproves-3.17
Histamine Issues From UbiomeImproves-2.72
Hyperlipidemia (High Blood Fats)Improves-2.72
IgA nephropathy (IgAN)Improves-2.72
Inflammatory Bowel DiseaseImproves-3.91
Irritable Bowel SyndromeImproves-4.09
Liver CirrhosisImproves-2.58
ME/CFS with IBSWorsen0
ME/CFS without IBSWorsen0
Multiple SclerosisImproves-3.68
Multiple system atrophy (MSA)Worsen2.72
Parkinson's DiseaseImproves-4.39
rheumatoid arthritis (RA),Spondyloarthritis (SpA)Improves-4.29
Stress / posttraumatic stress disorderWorsen2.72
Systemic Lupus ErythematosusImproves-3.54
Type 1 DiabetesImproves-4.14
Type 2 DiabetesWorsen3.26
Ulcerative colitisWorsen2.46

Bacteria Impacted

Suggest a missed study:

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

📓 - direct citation | 👪 - Impacts Parent Taxa | 👶 - Impacts Child Taxa | 🧙 - Inferred
Taxonomy Rank Effect Citations
Lachnospiraceae family Increases 📓 Source Study
Acetatifactor genus Increases 👪 Source Study
Acetitomaculum genus Increases 👪 Source Study
Agathobacter genus Increases 👪 Source Study
Anaerobium genus Increases 👪 Source Study
Anaerobutyricum genus Increases 👪 Source Study
Anaerocolumna genus Increases 👪 Source Study
Anaerosporobacter genus Increases 👪 Source Study
Anaerotaenia genus Increases 👪 Source Study
Anaerotignum genus Increases 👪 Source Study
Catonella genus Increases 👪 Source Study
Cellulosilyticum genus Increases 👪 Source Study
Eisenbergiella genus Increases 👪 Source Study
Faecalicatena genus Increases 👪 Source Study
Fusicatenibacter genus Increases 👪 Source Study
Herbinix genus Increases 👪 Source Study
Hespellia genus Increases 👪 Source Study
Johnsonella genus Increases 👪 Source Study
Lachnoanaerobaculum genus Increases 👪 Source Study
Lachnobacterium genus Increases 👪 Source Study
Lachnotalea genus Increases 👪 Source Study
Merdimonas genus Increases 👪 Source Study
Mobilitalea genus Increases 👪 Source Study
Moryella genus Increases 👪 Source Study
Murimonas genus Increases 👪 Source Study
Oribacterium genus Increases 👪 Source Study
Parasporobacterium genus Increases 👪 Source Study
Robinsoniella genus Increases 👪 Source Study
Sellimonas genus Increases 👪 Source Study
Shuttleworthia genus Increases 👪 Source Study
Sporobacterium genus Increases 👪 Source Study
Stomatobaculum genus Increases 👪 Source Study
Syntrophococcus genus Increases 👪 Source Study
Tyzzerella genus Increases 👪 Source Study
Bacillus genus Increases 📓 Source Study
Lactobacillus genus Increases 📓 Source Study
Roseburia genus Increases 📓 Source Study
Roseburia sp. species Increases 👪 Source Study
Roseburia sp. 1120 species Increases 👪 Source Study
Roseburia sp. 11SE38 species Increases 👪 Source Study
Roseburia sp. 499 species Increases 👪 Source Study
Roseburia sp. DJF_VR77 species Increases 👪 Source Study
Roseburia sp. MC_37 species Increases 👪 Source Study

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