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Cardiovascular Health: Saturated fats have long been associated with an increased risk of cardiovascular disease (CVD) when consumed in excess. High intake of saturated fat is linked to elevated levels of LDL (low-density lipoprotein) cholesterol, commonly known as "bad" cholesterol. LDL cholesterol can contribute to the buildup of plaque in the arteries, leading to atherosclerosis and an increased risk of heart attack and stroke.
Blood Lipid Levels: Consumption of saturated fat from dairy products may raise levels of total cholesterol, LDL cholesterol, and triglycerides in the blood, especially in individuals who are sensitive to dietary cholesterol. Elevated blood lipid levels are a major risk factor for CVD.
Obesity: Diets high in saturated fat can contribute to weight gain and obesity, particularly when consumed in excess of daily energy needs. Obesity is a significant risk factor for numerous chronic health conditions, including type 2 diabetes, hypertension, and cardiovascular disease.
Insulin Resistance and Diabetes: Some studies suggest that high intake of saturated fat, particularly from dairy sources, may increase the risk of insulin resistance and type 2 diabetes. Insulin resistance occurs when cells become less responsive to insulin, leading to elevated blood sugar levels and an increased risk of diabetes.
Inflammatory Conditions: Saturated fats have been implicated in promoting inflammation within the body, which is associated with various chronic diseases, including CVD, diabetes, and certain types of cancer. Inflammatory markers such as C-reactive protein (CRP) may be elevated in individuals consuming diets high in saturated fat.
Bone Health: While dairy products are a good source of calcium and vitamin D, which are important for bone health, excessive intake of saturated fat from dairy may have negative effects on bone density and increase the risk of osteoporosis. High-fat dairy products may also contain less calcium than their low-fat counterparts.
Digestive Issues: Some individuals may experience digestive discomfort or lactose intolerance when consuming high-fat dairy products, which can lead to symptoms such as bloating, gas, and diarrhea.
| Rank | Probiotic | Impact |
|---|
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
| Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
|---|---|---|---|
| Abdominal Aortic Aneurysm | 0.6 | -0.6 | |
| ADHD | 0.2 | -0.2 | |
| Alzheimer's disease | 0.6 | 0.8 | -0.33 |
| Ankylosing spondylitis | 0.2 | -0.2 | |
| Antiphospholipid syndrome (APS) | 0.6 | 0.6 | |
| Atrial fibrillation | 0.6 | 0.2 | 2 |
| Autism | 0.6 | 0.2 | 2 |
| Bipolar Disorder | 0.6 | -0.6 | |
| Brain Trauma | 0.2 | -0.2 | |
| Carcinoma | 0.6 | -0.6 | |
| Celiac Disease | 0.6 | 0.6 | 0 |
| COVID-19 | 0.6 | -0.6 | |
| Crohn's Disease | 0.2 | 0.8 | -3 |
| Depression | 0.2 | -0.2 | |
| giant cell arteritis | 0.2 | 0.2 | |
| Hashimoto's thyroiditis | 0.6 | 0.6 | |
| Hidradenitis Suppurativa | 0.6 | -0.6 | |
| hypersomnia | 0.6 | 0.6 | |
| hypertension (High Blood Pressure | 0.6 | 0.2 | 2 |
| Irritable Bowel Syndrome | 0.8 | -0.8 | |
| Liver Cirrhosis | 0.6 | 0.8 | -0.33 |
| Long COVID | 1.4 | 1.4 | |
| Metabolic Syndrome | 1.2 | 0.8 | 0.5 |
| Mood Disorders | 0.8 | -0.8 | |
| Multiple Sclerosis | 1.4 | -1.4 | |
| Obesity | 0.2 | 1.4 | -6 |
| Parkinson's Disease | 0.8 | -0.8 | |
| rheumatoid arthritis (RA),Spondyloarthritis (SpA) | 1.4 | -1.4 | |
| Schizophrenia | 0.8 | -0.8 | |
| scoliosis | 0.6 | 0.6 | |
| Small Intestinal Bacterial Overgrowth (SIBO) | 0.2 | -0.2 | |
| Systemic Lupus Erythematosus | 0.2 | 0.6 | -2 |
| Type 1 Diabetes | 0.6 | -0.6 | |
| Type 2 Diabetes | 0.8 | -0.8 | |
| Ulcerative colitis | 0.8 | 0.8 | |
| Unhealthy Ageing | 0.8 | -0.8 |
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