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🍽️ cinoxacin (antibiotic)

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  1. Urinary Tract Infections (UTIs): Cinoxacin is effective against a wide range of bacteria commonly implicated in urinary tract infections, including Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, and Enterobacter species. It is often prescribed for uncomplicated UTIs, such as cystitis and pyelonephritis, where it can help alleviate symptoms and eradicate the infection.

  2. Prostatitis: Cinoxacin may also be used in the treatment of bacterial prostatitis, an inflammation of the prostate gland usually caused by bacterial infection. It can penetrate prostatic tissues and achieve therapeutic concentrations in the prostate, making it effective against causative pathogens.

  3. Gastrointestinal Infections: In some cases, cinoxacin may be prescribed for gastrointestinal infections caused by susceptible bacteria. This includes infectious diarrhea caused by certain strains of bacteria such as Shigella and Salmonella.

  4. Respiratory Tract Infections: Cinoxacin is not typically used as a first-line treatment for respiratory tract infections. However, in some cases where the causative bacteria are known to be susceptible to cinoxacin, it may be considered for the treatment of respiratory infections such as bronchitis or pneumonia.

  5. Skin and Soft Tissue Infections: Cinoxacin is not commonly used to treat skin and soft tissue infections. Other antibiotics are usually preferred for these types of infections, as they may be more effective and have a lower risk of developing bacterial resistance.

  6. Side Effects: Like all antibiotics, cinoxacin can cause side effects. Common side effects may include nausea, vomiting, diarrhea, abdominal pain, headache, dizziness, and skin rash. Rare but serious side effects may include tendon rupture, particularly in older adults, and central nervous system effects such as seizures or hallucinations.

  7. Drug Interactions: Cinoxacin may interact with certain medications, potentially affecting their effectiveness or increasing the risk of side effects. It is important to inform your healthcare provider about all medications, supplements, and herbal products you are taking before starting cinoxacin therapy.

  8. Pregnancy and Lactation: The safety of cinoxacin use during pregnancy and lactation has not been well established. It is generally not recommended for use in pregnant or breastfeeding women unless the potential benefits outweigh the risks.

  9. Bacterial Resistance: Like other antibiotics, the overuse or misuse of cinoxacin can contribute to the development of bacterial resistance, reducing its effectiveness in treating infections. It is important to use cinoxacin judiciously and only when necessary to help preserve its efficacy.

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βš—οΈ Compensation for antibiotic usage

Data Contradictions β€” Limits of Certainity

Impacted of cinoxacin (antibiotic) On Probiotics

Rank Probiotic Impact
genus Bifidobacterium Reduces
species Akkermansia muciniphila Reduces
species Bacteroides uniformis Reduces
species Bifidobacterium longum Reduces
species Escherichia coli Reduces
subspecies Bifidobacterium longum subsp. infantis Reduces
subspecies Bifidobacterium longum subsp. longum Reduces

Bacteria Impacted by cinoxacin (antibiotic)

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

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Taxonomy Rank Effect Citations Notation
Akkermansiaceae family Decreases 👪 Source Study
Parabacteroides genus Decreases 👪 Source Study BMI, fat percent,blood pressure
Escherichia genus Decreases 👪 Source Study
Clostridium genus Decreases 👪 Source Study Pathogen
Phocaeicola genus Decreases 👪 Source Study
Fusobacterium genus Decreases 👪 Source Study Periodontal disease, Lemierre syndrome, skin ulcers
Clostridioides genus Decreases 👪 Source Study
Agathobacter genus Decreases 👪 Source Study
Bacteroides genus Decreases 👪 Source Study
Eggerthella genus Decreases 👪 Source Study
Roseburia genus Decreases 👪 Source Study
Coprococcus genus Decreases 👪 Source Study
Streptococcus genus Decreases 👪 Source Study
Bilophila genus Decreases 👪 Source Study High Level Cause Brain Fog(Cognitive impairment)
Mediterraneibacter genus Decreases 👪 Source Study
Bifidobacterium genus Decreases 👪 Source Study
Dorea genus Decreases 👪 Source Study
Thomasclavelia genus Decreases 👪 Source Study
Veillonella genus Decreases 👪 Source Study
Blautia genus Decreases 👪 Source Study
Akkermansia genus Decreases 📓 Source Study
Segatella genus Decreases 👪 Source Study
Escherichia coli O1:K1:H7 no rank Decreases 👶 Source Study
Escherichia coli O139:H1 no rank Decreases 👶 Source Study
Escherichia coli O141:H4 no rank Decreases 👶 Source Study
Escherichia coli O145:H34 no rank Decreases 👶 Source Study
Escherichia coli O15:H12 no rank Decreases 👶 Source Study
Escherichia coli O155:H21 no rank Decreases 👶 Source Study
Escherichia coli O158:H23 no rank Decreases 👶 Source Study
Escherichia coli O16:H48 no rank Decreases 👶 Source Study
Escherichia coli O170:H18 no rank Decreases 👶 Source Study
Escherichia coli O18ac:H14 no rank Decreases 👶 Source Study
Escherichia coli O19:H7 no rank Decreases 👶 Source Study
Escherichia coli O2:K1:H4 no rank Decreases 👶 Source Study
Escherichia coli O2:K1:H5 no rank Decreases 👶 Source Study
Escherichia coli O2:K1:H7 no rank Decreases 👶 Source Study
Escherichia coli O20:H12 no rank Decreases 👶 Source Study
Escherichia coli O25:H16 no rank Decreases 👶 Source Study
Escherichia coli O55:H7 no rank Decreases 👶 Source Study
Escherichia coli O68:H12 no rank Decreases 👶 Source Study
Escherichia coli O7:H15 no rank Decreases 👶 Source Study
Escherichia coli O78:H51 no rank Decreases 👶 Source Study
Escherichia coli O80:H26 no rank Decreases 👶 Source Study
Escherichia coli O84:H7 no rank Decreases 👶 Source Study
Escherichia coli O85:H1 no rank Decreases 👶 Source Study
Clostridium perfringens A no rank Decreases 👶 Source Study
Clostridium perfringens B no rank Decreases 👶 Source Study
Clostridium perfringens D no rank Decreases 👶 Source Study
Clostridium perfringens E no rank Decreases 👶 Source Study
environmental samples no rank Decreases 👶 Source Study
unclassified Akkermansia no rank Decreases 👶 Source Study
Escherichia coli O121 serogroup Decreases 👶 Source Study
Escherichia coli O145 serogroup Decreases 👶 Source Study
Escherichia coli O155 serogroup Decreases 👶 Source Study
Escherichia coli O157 serogroup Decreases 👶 Source Study
Escherichia coli O177 serogroup Decreases 👶 Source Study
Escherichia coli O26 serogroup Decreases 👶 Source Study
Escherichia coli O3 serogroup Decreases 👶 Source Study
Escherichia coli O43 serogroup Decreases 👶 Source Study
Escherichia coli O78 serogroup Decreases 👶 Source Study
Escherichia coli O86 serogroup Decreases 👶 Source Study
Escherichia coli O91 serogroup Decreases 👶 Source Study
Escherichia coli H20 serotype Decreases 👶 Source Study
Escherichia coli O1:H42 serotype Decreases 👶 Source Study
Escherichia coli O1:HNT serotype Decreases 👶 Source Study
Escherichia coli O10:H32 serotype Decreases 👶 Source Study
Escherichia coli O100:H21 serotype Decreases 👶 Source Study
Escherichia coli O103:H2 serotype Decreases 👶 Source Study
Escherichia coli O104:H4 serotype Decreases 👶 Source Study
Escherichia coli O111:H- serotype Decreases 👶 Source Study
Escherichia coli O111:H8 serotype Decreases 👶 Source Study
Escherichia coli O111:NM serotype Decreases 👶 Source Study
Escherichia coli O112ab:H8 serotype Decreases 👶 Source Study
Escherichia coli O112ac:H19 serotype Decreases 👶 Source Study
Escherichia coli O113:H21 serotype Decreases 👶 Source Study
Escherichia coli O114:H49 serotype Decreases 👶 Source Study
Escherichia coli O121:H19 serotype Decreases 👶 Source Study
Escherichia coli O125ac:K+:H10 serotype Decreases 👶 Source Study
Escherichia coli O126:H45 serotype Decreases 👶 Source Study
Escherichia coli O127:H6 serotype Decreases 👶 Source Study
Escherichia coli O128ac:H12 serotype Decreases 👶 Source Study
Escherichia coli O139:H28 serotype Decreases 👶 Source Study
Escherichia coli O145:H25 serotype Decreases 👶 Source Study
Escherichia coli O145:H28 serotype Decreases 👶 Source Study
Escherichia coli O145:NM serotype Decreases 👶 Source Study
Escherichia coli O15:H18 serotype Decreases 👶 Source Study
Escherichia coli O150:H6 serotype Decreases 👶 Source Study
Escherichia coli O152:H23 serotype Decreases 👶 Source Study
Escherichia coli O157:H- serotype Decreases 👶 Source Study
Escherichia coli O157:H43 serotype Decreases 👶 Source Study
Escherichia coli O157:H7 serotype Decreases 👶 Source Study bloody diarrhea
Escherichia coli O16:H6 serotype Decreases 👶 Source Study
Escherichia coli O167:H26 serotype Decreases 👶 Source Study
Escherichia coli O174:H21 serotype Decreases 👶 Source Study
Escherichia coli O176:H45 serotype Decreases 👶 Source Study
Escherichia coli O2:H6 serotype Decreases 👶 Source Study
Escherichia coli O2:K2:H1 serotype Decreases 👶 Source Study
Escherichia coli O25:H1 serotype Decreases 👶 Source Study
Escherichia coli O25:NM serotype Decreases 👶 Source Study
Escherichia coli O26:H11 serotype Decreases 👶 Source Study
Escherichia coli O44:H18 serotype Decreases 👶 Source Study
Escherichia coli O45:H2 serotype Decreases 👶 Source Study
Escherichia coli O6:H16 serotype Decreases 👶 Source Study
Escherichia coli O6:K2:H1 serotype Decreases 👶 Source Study
Escherichia coli O7:H4 serotype Decreases 👶 Source Study
Escherichia coli O7:K1 serotype Decreases 👶 Source Study
Escherichia coli O78:H4 serotype Decreases 👶 Source Study
Escherichia coli O8:H8 serotype Decreases 👶 Source Study
Escherichia coli O89m:H10 serotype Decreases 👶 Source Study
Escherichia coli O89m:H9 serotype Decreases 👶 Source Study
Escherichia coli O9:H10 serotype Decreases 👶 Source Study
Escherichia coli O99:H6 serotype Decreases 👶 Source Study
Parabacteroides merdae species Decreases 📓 Source Study Infectious bacteria
Escherichia coli species Decreases 📓 Source Study Diarrheal disease in children and travelers, Foodborne diarrhea outbreaks, hemorrhagic colitis, hemolytic-uremic syndrome
Clostridium perfringens species Decreases 📓 Source Study Food poisoning, gas gangrene
Phocaeicola vulgatus species Decreases 📓 Source Study
Fusobacterium nucleatum species Decreases 📓 Source Study Infectious bacteria
Bacteroides fragilis species Decreases 📓 Source Study H02076 Bacteroides infection
Clostridioides difficile species Decreases 📓 Source Study Colitis
Bacteroides uniformis species Decreases 📓 Source Study Infectious bacteria
Roseburia intestinalis species Decreases 📓 Source Study
Agathobacter rectalis species Decreases 📓 Source Study
Eggerthella lenta species Decreases 📓 Source Study
Coprococcus comes species Decreases 📓 Source Study
Streptococcus parasanguinis species Decreases 📓 Source Study
Bilophila wadsworthia species Decreases 📓 Source Study
Mediterraneibacter gnavus species Decreases 📓 Source Study
Bacteroides thetaiotaomicron species Decreases 📓 Source Study
Bifidobacterium longum species Decreases 📓 Source Study
Dorea formicigenerans species Decreases 📓 Source Study
Thomasclavelia ramosa species Decreases 📓 Source Study
Veillonella parvula species Decreases 📓 Source Study
Blautia obeum species Decreases 📓 Source Study
Akkermansia muciniphila species Decreases 📓 Source Study High Levels linked to long-lived individuals
Roseburia hominis species Decreases 📓 Source Study
Segatella copri species Decreases 📓 Source Study Over 70%ile Indicator of mycotoxin present
Bacteroides caccae species Decreases 📓 Source Study
Akkermansia glycaniphila species Decreases 👶 Source Study
Candidatus Akkermansia intestinavium species Decreases 👶 Source Study
Fusobacterium nucleatum subsp. nucleatum subspecies Decreases 👶 Source Study
Bifidobacterium longum subsp. infantis subspecies Decreases 👶 Source Study
Bifidobacterium longum subsp. longum subspecies Decreases 👶 Source Study
Bifidobacterium longum subsp. suillum subspecies Decreases 👶 Source Study

Impact of cinoxacin (antibiotic) on Conditions from US National Library of Medicine

A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.

We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive   X|increases + Y|decrease = Negative.

Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.

Condition Positive Impact Negative Impact Benefit Ratio Impact
Abdominal Aortic Aneurysm 0.1 0.1
Acne 0.1 -0.1
ADHD 1.8 0.3 5
Age-Related Macular Degeneration and Glaucoma 0.2 0.5 -1.5
Allergic Rhinitis (Hay Fever) 1.8 0.2 8
Allergies 2.6 0.6 3.33
Allergy to milk products 1.7 1.1 0.55
Alopecia (Hair Loss) 0.1 0.1
Alzheimer's disease 3 2.3 0.3
Amyotrophic lateral sclerosis (ALS) Motor Neuron 1.4 1 0.4
Ankylosing spondylitis 1.8 0.6 2
Anorexia Nervosa 0.5 1 -1
Antiphospholipid syndrome (APS) 1.7 0.1 16
Asthma 0.8 0.4 1
Atherosclerosis 0.4 1.1 -1.75
Atrial fibrillation 1.2 1.3 -0.08
Autism 5.3 4.2 0.26
Barrett esophagus cancer 0.4 0.1 3
benign prostatic hyperplasia 0.5 0.5
Biofilm 2 2
Bipolar Disorder 1.2 0.4 2
Brain Trauma 0.1 0.3 -2
Cancer (General) 1.2 -1.2
Carcinoma 1.6 0.8 1
Celiac Disease 2.1 1 1.1
Cerebral Palsy 0.7 0.3 1.33
Chronic Fatigue Syndrome 3.3 3.2 0.03
Chronic Kidney Disease 1.4 0.6 1.33
Chronic Lyme 0.3 -0.3
Chronic Obstructive Pulmonary Disease (COPD) 0.7 0.2 2.5
Chronic Urticaria (Hives) 2.1 0.7 2
Coagulation / Micro clot triggering bacteria 2.1 0.3 6
Colorectal Cancer 3.9 0.2 18.5
Constipation 1.4 0.2 6
Coronary artery disease 0.3 0.2 0.5
COVID-19 5.7 3.7 0.54
Crohn's Disease 5.6 2.3 1.43
cystic fibrosis 1.5 0.3 4
deep vein thrombosis 1.5 0.2 6.5
Depression 4.3 4.1 0.05
Dermatomyositis 0.1 0.1 0
Eczema 0.7 1.2 -0.71
Endometriosis 2.5 0 0
Eosinophilic Esophagitis 0.3 0 0
Epilepsy 1.8 1.8 0
Fibromyalgia 2.3 1.5 0.53
Functional constipation / chronic idiopathic constipation 4.7 1.6 1.94
gallstone disease (gsd) 1.6 0.5 2.2
Gastroesophageal reflux disease (Gerd) including Barrett's esophagus 1.7 0.2 7.5
Generalized anxiety disorder 2 0.9 1.22
giant cell arteritis 0.5 -0.5
Glioblastoma 0.1 -0.1
Gout 0.1 -0.1
Graves' disease 0.7 0.2 2.5
Halitosis 0.5 0.1 4
Hashimoto's thyroiditis 0.4 0.3 0.33
Hidradenitis Suppurativa 0.5 0 0
High Histamine/low DAO 2.6 0.1 25
hypercholesterolemia (High Cholesterol) 0.5 0 0
hyperglycemia 0.5 0.8 -0.6
Hyperlipidemia (High Blood Fats) 0.1 0.1
hypersomnia 0.1 -0.1
hypertension (High Blood Pressure 1.3 1.5 -0.15
Hypothyroidism 0.3 -0.3
Hypoxia 0.7 0.7
IgA nephropathy (IgAN) 1.4 -1.4
Inflammatory Bowel Disease 2.8 2.8 0
Insomnia 0.3 0.3 0
Intelligence 1.2 0 0
Intracranial aneurysms 0.7 0.7
Irritable Bowel Syndrome 2.6 2.3 0.13
Liver Cirrhosis 2.6 1.2 1.17
Long COVID 3.4 1.9 0.79
Low bone mineral density 0.2 -0.2
Lung Cancer 0.5 0.1 4
Mast Cell Issues / mastitis 0.6 0.2 2
ME/CFS with IBS 0.6 0.6 0
ME/CFS without IBS 1.2 0.4 2
Menopause 0.1 0.1
Metabolic Syndrome 4.5 4.2 0.07
Mood Disorders 5.6 4.2 0.33
multiple chemical sensitivity [MCS] 0.2 0 0
Multiple Sclerosis 2 3.4 -0.7
Multiple system atrophy (MSA) 0.3 0.1 2
neuropathic pain 0.3 -0.3
Neuropathy (all types) 0.2 0.5 -1.5
neuropsychiatric disorders (PANDAS, PANS) 1 1
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic 1.2 0.9 0.33
NonCeliac Gluten Sensitivity 0.3 0.2 0.5
Obesity 2.6 1.3 1
obsessive-compulsive disorder 4.8 0.8 5
Osteoarthritis 1.5 1.5
Osteoporosis 1.3 0.2 5.5
pancreatic cancer 0.1 0.1
Parkinson's Disease 3.9 3.2 0.22
Polycystic ovary syndrome 2.5 0.7 2.57
Postural orthostatic tachycardia syndrome 0.5 0.2 1.5
Premenstrual dysphoric disorder 0.1 0.5 -4
primary biliary cholangitis 0 0.5 0
Psoriasis 2.4 1 1.4
rheumatoid arthritis (RA),Spondyloarthritis (SpA) 2.7 2 0.35
Rosacea 0.1 0.6 -5
Schizophrenia 3.3 0.8 3.12
scoliosis 0.1 0.1 0
Sjögren syndrome 1.3 1.5 -0.15
Sleep Apnea 0.5 0.6 -0.2
Slow gastric motility / Gastroparesis 1.2 0.1 11
Small Intestinal Bacterial Overgrowth (SIBO) 1.4 0.1 13
Stress / posttraumatic stress disorder 2.7 0.8 2.38
Systemic Lupus Erythematosus 2.7 0.2 12.5
Tic Disorder 0.8 0.1 7
Tourette syndrome 0 0.2 0
Type 1 Diabetes 2.3 1.5 0.53
Type 2 Diabetes 4.7 5.1 -0.09
Ulcerative colitis 2.4 3 -0.25
Unhealthy Ageing 3.7 0.7 4.29
Vitiligo 0.7 1.3 -0.86

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