AI Engines For more Details: Perplexity Kagi Labs You
Antithyroid Effects: Methimazole works by inhibiting the production of thyroid hormones, particularly thyroxine (T4) and triiodothyronine (T3), by interfering with the function of the enzyme thyroperoxidase. This helps to reduce the levels of thyroid hormones in the body, thereby normalizing thyroid function in individuals with hyperthyroidism.
Treatment of Hyperthyroidism: Methimazole is commonly prescribed for the management of hyperthyroidism, including conditions such as Graves' disease, toxic multinodular goiter, and toxic adenoma. By lowering thyroid hormone levels, it helps alleviate symptoms associated with hyperthyroidism, such as rapid heart rate, weight loss, tremors, sweating, heat intolerance, and fatigue.
Maintenance Therapy: Methimazole is often used as a long-term maintenance therapy for hyperthyroidism, particularly in individuals who are not candidates for definitive treatments such as radioactive iodine therapy or thyroidectomy. It helps to control thyroid function and prevent the recurrence of hyperthyroid symptoms.
Side Effects: Common side effects of methimazole may include nausea, vomiting, upset stomach, headache, dizziness, joint or muscle pain, hair loss, and skin rash. These side effects are usually mild and transient but may necessitate dose adjustments or discontinuation of the medication in some cases.
Rare but Serious Side Effects: In rare cases, methimazole may cause more serious adverse reactions, such as agranulocytosis (a severe decrease in white blood cell count), which can increase the risk of infections. Other rare side effects may include hepatotoxicity (liver damage), pancreatitis, and allergic reactions such as Stevens-Johnson syndrome or toxic epidermal necrolysis.
Monitoring: Individuals taking methimazole typically require regular monitoring of thyroid function tests, including thyroid hormone levels (TSH, T4, and T3), to assess the response to treatment and adjust the medication dosage as needed. Monitoring for signs of adverse effects, such as fever, sore throat, bruising, or jaundice, is also important.
Pregnancy and Breastfeeding: Methimazole should be used with caution during pregnancy, particularly during the first trimester, as it may cross the placenta and affect fetal thyroid function. It may be used in pregnant women with hyperthyroidism, but the lowest effective dose should be used to minimize the risk of adverse effects on the fetus. Methimazole can also be transferred to breast milk, so breastfeeding while taking methimazole should be discussed with a healthcare provider.
Drug Interactions: Methimazole may interact with other medications, including anticoagulants (blood thinners) such as warfarin, increasing the risk of bleeding. It may also interact with certain drugs that affect liver function or metabolism.
| Rank | Probiotic | Impact |
|---|---|---|
| species | Bifidobacterium longum | Reduces |
| species | Escherichia coli | Reduces |
| subspecies | Bifidobacterium longum subsp. infantis | Reduces |
| subspecies | Bifidobacterium longum subsp. longum | Reduces |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
| Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
|---|---|---|---|
| Acne | 0.2 | -0.2 | |
| ADHD | 2 | 0.3 | 5.67 |
| Age-Related Macular Degeneration and Glaucoma | 0.5 | 0.5 | |
| Allergic Rhinitis (Hay Fever) | 0.4 | 0.6 | -0.5 |
| Allergies | 1.7 | 0.9 | 0.89 |
| Allergy to milk products | 0.6 | 0.4 | 0.5 |
| Alopecia (Hair Loss) | 0.5 | 0.5 | |
| Alzheimer's disease | 1.2 | 2.7 | -1.25 |
| Amyotrophic lateral sclerosis (ALS) Motor Neuron | 0.7 | 0.4 | 0.75 |
| Ankylosing spondylitis | 2.5 | 0.3 | 7.33 |
| Anorexia Nervosa | 1.2 | -1.2 | |
| Antiphospholipid syndrome (APS) | 1.8 | 1.8 | |
| Asthma | 0.2 | 0.7 | -2.5 |
| Atherosclerosis | 0.2 | 1.5 | -6.5 |
| Atrial fibrillation | 1.6 | 1.4 | 0.14 |
| Autism | 4.7 | 4.2 | 0.12 |
| Barrett esophagus cancer | 0 | 0.4 | 0 |
| benign prostatic hyperplasia | 0.2 | 0.2 | |
| Biofilm | 0.5 | 0.5 | |
| Bipolar Disorder | 0.4 | 0.8 | -1 |
| Brain Trauma | 0.2 | 0.7 | -2.5 |
| Cancer (General) | 0.6 | -0.6 | |
| Carcinoma | 1.5 | 0.9 | 0.67 |
| Celiac Disease | 1.7 | 1.3 | 0.31 |
| Cerebral Palsy | 0.7 | 1.2 | -0.71 |
| Chronic Fatigue Syndrome | 3.1 | 3.4 | -0.1 |
| Chronic Kidney Disease | 1.4 | 0.8 | 0.75 |
| Chronic Lyme | 0.7 | -0.7 | |
| Chronic Obstructive Pulmonary Disease (COPD) | 1.3 | 0.8 | 0.63 |
| Chronic Urticaria (Hives) | 1 | 0.8 | 0.25 |
| Coagulation / Micro clot triggering bacteria | 1 | 1.4 | -0.4 |
| Colorectal Cancer | 2.5 | 0.2 | 11.5 |
| Constipation | 1.1 | 1 | 0.1 |
| Coronary artery disease | 0.8 | -0.8 | |
| COVID-19 | 4.2 | 7.3 | -0.74 |
| Crohn's Disease | 3 | 1.7 | 0.76 |
| cystic fibrosis | 0.6 | 0.9 | -0.5 |
| deep vein thrombosis | 0.6 | 0.9 | -0.5 |
| Depression | 3.7 | 3.4 | 0.09 |
| Dermatomyositis | 0.4 | 0.2 | 1 |
| Eczema | 0.2 | 1.5 | -6.5 |
| Endometriosis | 2.2 | 2.2 | |
| Eosinophilic Esophagitis | 0 | 0 | |
| Epilepsy | 1.6 | 0.9 | 0.78 |
| Fibromyalgia | 1 | 2.5 | -1.5 |
| Functional constipation / chronic idiopathic constipation | 3.3 | 3.1 | 0.06 |
| gallstone disease (gsd) | 0.7 | 0.7 | 0 |
| Gastroesophageal reflux disease (Gerd) including Barrett's esophagus | 0.7 | 1.4 | -1 |
| Generalized anxiety disorder | 1.1 | 1.2 | -0.09 |
| giant cell arteritis | 0 | 0 | |
| Glioblastoma | 0.4 | -0.4 | |
| Gout | 0.3 | -0.3 | |
| Graves' disease | 0.4 | 1 | -1.5 |
| Halitosis | 0.3 | 0.4 | -0.33 |
| Hashimoto's thyroiditis | 2.4 | 0.4 | 5 |
| Hidradenitis Suppurativa | 0.5 | 0.5 | |
| High Histamine/low DAO | 1 | 0.2 | 4 |
| hypercholesterolemia (High Cholesterol) | 0 | 0 | |
| hyperglycemia | 0.2 | 0.9 | -3.5 |
| Hyperlipidemia (High Blood Fats) | 0.2 | 0.2 | |
| hypersomnia | 0.5 | -0.5 | |
| hypertension (High Blood Pressure | 1.1 | 2.5 | -1.27 |
| Hypothyroidism | 1 | -1 | |
| Hypoxia | 0.2 | 0.2 | |
| IgA nephropathy (IgAN) | 1.9 | -1.9 | |
| Inflammatory Bowel Disease | 2.3 | 3.9 | -0.7 |
| Insomnia | 1.1 | 0.7 | 0.57 |
| Intelligence | 1 | 0.8 | 0.25 |
| Intracranial aneurysms | 0.7 | 0.7 | |
| Irritable Bowel Syndrome | 1.5 | 2.5 | -0.67 |
| Liver Cirrhosis | 2.4 | 1.7 | 0.41 |
| Long COVID | 3.1 | 3.1 | 0 |
| Low bone mineral density | 0.8 | -0.8 | |
| Lung Cancer | 0.2 | 0.5 | -1.5 |
| Mast Cell Issues / mastitis | 0.6 | 0.5 | 0.2 |
| ME/CFS with IBS | 0.7 | 2 | -1.86 |
| ME/CFS without IBS | 0.6 | 0.4 | 0.5 |
| Menopause | 0.7 | 0.7 | |
| Metabolic Syndrome | 2.8 | 4 | -0.43 |
| Mood Disorders | 4.1 | 3.4 | 0.21 |
| multiple chemical sensitivity [MCS] | 1.3 | 0.5 | 1.6 |
| Multiple Sclerosis | 2.4 | 2.1 | 0.14 |
| Multiple system atrophy (MSA) | 0.7 | -0.7 | |
| neuropathic pain | 0.4 | -0.4 | |
| Neuropathy (all types) | 0.9 | 0.2 | 3.5 |
| neuropsychiatric disorders (PANDAS, PANS) | 0.4 | 0.4 | |
| Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | 2 | 2.6 | -0.3 |
| NonCeliac Gluten Sensitivity | 0.7 | 0.4 | 0.75 |
| Obesity | 3.4 | 2.1 | 0.62 |
| obsessive-compulsive disorder | 3.7 | 3 | 0.23 |
| Osteoarthritis | 0.9 | 0.9 | |
| Osteoporosis | 0.4 | 0.7 | -0.75 |
| pancreatic cancer | 0.4 | 0.4 | |
| Parkinson's Disease | 3.7 | 4 | -0.08 |
| Polycystic ovary syndrome | 1.6 | 0.7 | 1.29 |
| Postural orthostatic tachycardia syndrome | 0 | 0.5 | 0 |
| Premenstrual dysphoric disorder | 0.7 | 0.7 | |
| primary biliary cholangitis | 0.6 | -0.6 | |
| Psoriasis | 1.5 | 1.9 | -0.27 |
| rheumatoid arthritis (RA),Spondyloarthritis (SpA) | 3.2 | 1.3 | 1.46 |
| Rosacea | 1.2 | 0.5 | 1.4 |
| Schizophrenia | 1.8 | 1.5 | 0.2 |
| scoliosis | 0.3 | 0.3 | |
| Sjögren syndrome | 1.9 | 1.5 | 0.27 |
| Sleep Apnea | 1 | 1.5 | -0.5 |
| Slow gastric motility / Gastroparesis | 0.6 | 0.2 | 2 |
| Small Intestinal Bacterial Overgrowth (SIBO) | 0.9 | 0.4 | 1.25 |
| Stress / posttraumatic stress disorder | 1.4 | 1.2 | 0.17 |
| Systemic Lupus Erythematosus | 1.7 | 1.2 | 0.42 |
| Tic Disorder | 0.6 | 1 | -0.67 |
| Tourette syndrome | 0.2 | -0.2 | |
| Type 1 Diabetes | 2.1 | 1.6 | 0.31 |
| Type 2 Diabetes | 3.4 | 4 | -0.18 |
| Ulcerative colitis | 1.9 | 3.6 | -0.89 |
| Unhealthy Ageing | 3 | 1 | 2 |
This is an Academic site. It generates theoretical models of what may benefit a specific microbiome results.
Explanations / Info / Descriptions are influenced by < a href = "/home/sources" target = "_blank" > Large Language Models and may not be accurate and include some hallucinations.Please report any to us for correction.
Copyright 2016 - 2024 Lassesen Consulting, LLC[2007], DBA, Microbiome Prescription
All rights served.
Permission to data scrap or reverse engineer is explicitly denied to all users.U.S.Code Title 18 PART I CHAPTER 47 § 1030, CETS No.185, CFAA
Use of data on this site is prohibited except under written license.There is no charge for individual personal use.Use for any commercial applications or research requires a written license.
Caveat emptor: Analysis and suggestions are based on modelling(and thus infererence ) based on studies.The data sources are usually given for those that wish to consider alternative inferences.theories and models.
Inventions / Methodologies on this site are Patent Pending.
Microbiome Prescription do not make any representations that data or analyses available on this site is suitable for human diagnostic purposes, for informing treatment decisions,
or for any other purposes and accept no responsibility or liability whatsoever for such use.
This site is not in strict compliance with Personal Health Information Laws. [44.222.131 ]
Due to AI drones slamming this site, we have added IP blocking on excessive calls. Email us if you get blocked and send this [44.222.131 ]
