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Citizen Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a symptom. There are many bacteria involved. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is based on associations discovered from annotated 16s microbiome samples. See this post for more information.

SymptomImpactPredictor of Bacteria Shift
Age: 0-10Worsen2.03
Age: 10-20Improves-2.96
Age: 20-30Improves-3.07
Age: 30-40Improves-3.1
Age: 40-50Improves-2.41
Age: 50-60Improves-3.31
Age: 60-70Worsen3.16
Asymptomatic: Live in house with person with probable microbiome dysfunctionWorsen0.05
Asymptomatic: Minor Health Issues (a few symptoms only)Improves-2.03
Asymptomatic: No Health IssuesImproves-2.19
Autism: Official DiagnosisWorsen3.69
Autonomic Manifestations: cardiac arrhythmiasImproves-2.03
Autonomic Manifestations: Cortisol disorders or irregularity Improves-2.62
Autonomic Manifestations: irritable bowel syndromeImproves-3.17
Autonomic Manifestations: light-headednessImproves-3.68
Autonomic Manifestations: Orthostatic intoleranceImproves-2.36
Autonomic Manifestations: palpitationsImproves-3.07
Autonomic Manifestations: Postural orthostatic tachycardia syndrome (POTS)Improves-3.28
Autonomic Manifestations: urinary frequency dysfunctionImproves-3.66
Autonomic: Blurred or tunnel vision after standingImproves-2.03
Autonomic: Dizziness or faintingImproves-2.76
Autonomic: Heart rate increase after standingImproves-3.1
Autonomic: Inability to tolerate an upright positionWorsen3.67
Autonomic: Irregular heartbeatsImproves-1.29
Autonomic: NauseaImproves-3.07
Autonomic: Ocassional Tachycardia (Rapid heart beat)Improves-3.31
Autonomic: Shortness of breathImproves-3.47
Blood Type: A PositiveWorsen1.88
Blood Type: O PositiveWorsen4.04
Comorbid-Mouth: Bruxism - Jaw cleanching / Teeth grindingImproves-3.1
Comorbid-Mouth: Dry MouthImproves-3.18
Comorbid-Mouth: Gingivits / Gum DiseaseWorsen2.03
Comorbid-Mouth: Mouth SoresImproves-2.38
Comorbid-Mouth: TMJ / Dysfunction of the temporomandibular joint syndromeWorsen3.14
Comorbid: Constipation and Explosions (not diarrohea)Worsen4.13
Comorbid: FibromyalgiaImproves-3.56
Comorbid: High AnxietyWorsen3.36
Comorbid: Histamine or Mast Cell issuesWorsen2.95
Comorbid: HypothyroidismWorsen2.01
Comorbid: Inflammatory bowel disease Worsen3.24
Comorbid: Methylation issues (MTHFR)Improves-2.95
Comorbid: MigraineImproves-1.92
Comorbid: Mold Sensitivity / ExposureImproves-2.81
Comorbid: Multiple Chemical SensitivityImproves-3.07
Comorbid: Small intestinal bacterial overgrowth (SIBO)Improves-3.17
Comorbid: Snoring (NOT Sleep ApneaWorsen4.05
Condition: ME/CFS with IBSWorsen1.27
DePaul University Fatigue Questionnaire : AllergiesImproves-2.75
DePaul University Fatigue Questionnaire : Anxiety/tensionWorsen1.33
DePaul University Fatigue Questionnaire : DepressionImproves-1.24
DePaul University Fatigue Questionnaire : Difficulty comprehending InformationImproves-2.53
DePaul University Fatigue Questionnaire : Difficulty falling asleepImproves-1.92
DePaul University Fatigue Questionnaire : Difficulty finding the right wordImproves-2.12
DePaul University Fatigue Questionnaire : Difficulty staying asleepImproves-2.6
DePaul University Fatigue Questionnaire : DizzinessWorsen3.05
DePaul University Fatigue Questionnaire : FatigueImproves-2.56
DePaul University Fatigue Questionnaire : Forgetting what you are trying to sayImproves-2.47
DePaul University Fatigue Questionnaire : Impaired Memory & concentrationWorsen1.92
DePaul University Fatigue Questionnaire : Unrefreshing Sleep, that is waking up feeling tired Worsen2.52
DePaul University Fatigue Questionnaire : Walking up early in the morning (e.g. 3AM)Improves-2.53
Gender: FemaleImproves-3.57
Gender: MaleImproves-2.54
General: DepressionImproves-2.98
General: FatigueImproves-3.88
General: HeadachesImproves-3.74
General: Heavy feeling in arms and legsImproves-2.8
General: Myalgia (pain)Improves-3.78
General: Sinus issues with headachesWorsen2.95
Immune Manifestations: Abdominal PainWorsen3.26
Immune Manifestations: Alcohol IntolerantWorsen3.96
Immune Manifestations: BloatingImproves-3.57
Immune Manifestations: ConstipationImproves-3.25
Immune Manifestations: DiarrheaImproves-3.68
Immune Manifestations: general malaiseImproves-3.36
Immune Manifestations: Hair lossImproves-3.17
Immune Manifestations: Inflammation (General)Improves-2.36
Immune Manifestations: Inflammation of skin, eyes or jointsImproves-2.36
Immune Manifestations: medication sensitivities.Improves-2.36
Immune Manifestations: Mucus in the stoolWorsen3.67
Immune Manifestations: new food sensitivitiesImproves-2.6
Immune Manifestations: tender lymph nodesWorsen2.03
Immune: Recurrent Sore throatImproves-2.99
Immune: Sensitivity to smell/food/medication/chemicalsImproves-3.17
Immune: Viral infections with prolonged recovery periodsImproves-2.99
Infection: Epstein-Barr virusImproves-2.36
Infection: Human Herpesvirus 6 (HHV6)Worsen4.08
Infection: MycoplasmaWorsen3.67
Infection: Parasite - OtherWorsen3.36
Joint: RednessImproves-2.38
Joint: Stiffness and swellingWorsen2.95
Joint: Sudden and severe episodes of painImproves-2.03
Joint: TendernessWorsen2.45
Neurocognitive: Absent-mindedness or forgetfulnessImproves-3.57
Neurocognitive: Brain FogImproves-3.1
Neurocognitive: Can only focus on one thing at a timeImproves-3.57
Neurocognitive: Difficulty expressing thoughtsImproves-3.1
Neurocognitive: Difficulty paying attention for a long period of timeImproves-3.17
Neurocognitive: Difficulty understanding thingsImproves-3.03
Neurocognitive: Problems remembering thingsImproves-3.57
Neurocognitive: Slowness of thoughtImproves-3.98
Neurocognitive: Unable to focus vision and/or attentionImproves-3.57
Neuroendocrine Manifestations: abnormal appetiteImproves-3.07
Neuroendocrine Manifestations: Air HungerImproves-2.12
Neuroendocrine Manifestations: cold extremitiesImproves-3.52
Neuroendocrine Manifestations: Dry Eye (Sicca or Sjogren Syndrome)Improves-3.31
Neuroendocrine Manifestations: Excessive adrenalineImproves-2.23
Neuroendocrine Manifestations: intolerance of extremes of heat and coldImproves-2.74
Neuroendocrine Manifestations: marked weight change Improves-3.31
Neuroendocrine Manifestations: Muscle weakness Improves-3.78
Neuroendocrine Manifestations: NeuralgiaImproves-3.5
Neuroendocrine Manifestations: Paraesthesia (tingling burning of skin)Worsen3.24
Neuroendocrine Manifestations: Rapid muscular fatiguabilityImproves-3.45
Neuroendocrine Manifestations: recurrent feelings of feverishnessImproves-2.12
Neuroendocrine Manifestations: subnormal body temperatureImproves-2.72
Neuroendocrine Manifestations: sweating episodesImproves-2.36
Neuroendocrine Manifestations: worsening of symptoms with stress.Improves-3.98
Neuroendocrine: Alcohol intoleranceWorsen2.45
Neuroendocrine: Chills or shiversImproves-2.03
Neuroendocrine: Cold limbs (e.g. arms, legs hands)Improves-3.55
Neuroendocrine: Feeling hot or cold for no reasonImproves-3.1
Neuroendocrine: Lack of appetiteImproves-2.03
Neuroendocrine: Lost or gained weight without tryingImproves-3.87
Neuroendocrine: Sweating handsImproves-2.03
Neuroendocrine: Temperature fluctuations throughout the dayImproves-2.03
Neurological-Audio: hypersensitivity to noiseImproves-3.36
Neurological-Audio: Tinnitus (ringing in ear)Improves-3.1
Neurological-Sleep: Chaotic diurnal sleep rhythms (Erratic Sleep)Worsen2.71
Neurological-Sleep: InsomniaWorsen1.47
Neurological-Sleep: Night SweatsImproves-3.33
Neurological-Sleep: Sleep ApneaImproves-1.91
Neurological-Sleep: Vivid Dreams/NightmaresImproves-2.95
Neurological-Vision: Blurred VisionImproves-2.12
Neurological-Vision: inability to focus eye/visionWorsen4.05
Neurological-Vision: photophobia (Light Sensitivity)Worsen2.45
Neurological: Cognitive/Sensory OverloadImproves-3.02
Neurological: ConfusionWorsen2.03
Neurological: Difficulty processing information (Understanding)Improves-3.66
Neurological: Difficulty readingImproves-0.08
Neurological: DysautonomiaWorsen1.66
Neurological: emotional overloadImproves-3.31
Neurological: Executive Decision Making (Difficulty making)Improves-2.36
Neurological: fasciculations Improves-3.19
Neurological: Impairment of concentrationImproves-3.17
Neurological: Joint hypermobilityWorsen3.81
Neurological: Neuropathy Worsen2.03
Neurological: Seasonal Affective Disorder (SAD)Worsen2.8
Neurological: Short-term memory issuesImproves-3.75
Neurological: Slowed speechWorsen0.57
Neurological: Spatial instability and disorientationImproves-2.03
Neurological: Word-finding problemsImproves-3.1
Official Diagnosis: Allergic Rhinitis (Hay Fever)Worsen3.79
Official Diagnosis: Autoimmune DiseaseWorsen2.95
Official Diagnosis: Chronic Fatigue SyndromeImproves-3.57
Official Diagnosis: Inflammatory Bowel Disease (IBD)Worsen2.91
Official Diagnosis: Irritable Bowel SyndromeWorsen2.02
Official Diagnosis: Mast Cell DysfunctionWorsen3.82
Onset: 2000-2010Worsen2.03
Onset: 2010-2020Improves-2.36
Onset: GradualImproves-3.8
Onset: less than 02 years since onsetImproves-2.96
Onset: less than 16 years since onsetImproves-2.7
Other: Sensitivity to moldImproves-0.99
Other: Sensitivity to vibrationsImproves-3.14
Pain: Aching of the eyes or behind the eyesWorsen2.03
Pain: Chest painImproves-3.07
Pain: Eye painWorsen2.03
Pain: Joint painImproves-3.25
Pain: Myofascial painWorsen2.03
Pain: Pain or aching in musclesImproves-3.31
Pain: Sensitivity to painWorsen3.79
Post-exertional malaise: Difficulty reading after mild physical or mental activityImproves-1.36
Post-exertional malaise: GeneralImproves-3.37
Post-exertional malaise: Mentally tired after the slightest effortImproves-3.57
Post-exertional malaise: Muscle fatigue after mild physical activityImproves-2.36
Post-exertional malaise: Physically drained or sick after mild activityImproves-3.57
Post-exertional malaise: Physically tired after minimum exerciseImproves-2.36
Post-exertional malaise: Post-exertional malaiseImproves-3.1
Post-exertional malaise: Rapid cognitive fatigability, Improves-3.47
Post-exertional malaise: Rapid muscular fatigability, Improves-3.57
Post-exertional malaise: Worsening of symptoms after mild mental activityImproves-2
Post-exertional malaise: Worsening of symptoms after mild physical activityImproves-3.1
Sleep: Daytime drowsinessImproves-2.36
Sleep: Need to nap dailyImproves-3.5
Sleep: Problems falling asleepImproves-3.02
Sleep: Problems staying asleepImproves-3.17
Sleep: Unrefreshed sleepImproves-3.57
Sleep: Waking up early in the morning (e.g. 3 AM)Improves-2.36

Published Science Infered Impact

We take what shifts this modifier is known to make and the shifts reported for a medical condition. There are many bacteria. We sum all of the shifts (some positive and some negative) to estimate a predictor. Some bacteria may have greater impact (that information is not available in 99% of studies) so the estimate can be wrong in edge cases.

This is according to the microbiome shifts reported in studies. Clinical studies may show different results

SymptomImpactPredictor of Bacteria Shift
ADHDImproves-1.32
Allergic Rhinitis (Hay Fever)Worsen2.64
AllergiesWorsen2.45
Alzheimer's diseaseWorsen0
Amyotrophic lateral sclerosis (ALS) Motor NeuronWorsen1.7
Ankylosing spondylitisWorsen3.75
Anorexia NervosaImproves-3.18
AtherosclerosisWorsen4.34
AutismImproves-4.13
CarcinomaWorsen0
Celiac DiseaseImproves-3.24
Cerebral PalsyImproves-3.05
Chronic Fatigue SyndromeWorsen1.22
Chronic Kidney DiseaseWorsen3.22
Chronic Urticaria (Hives)Improves-1.63
Colorectal CancerWorsen4.23
Coronary artery disease Improves-1.09
COVID-19Improves-1.95
Crohn's DiseaseImproves-1.52
DepressionImproves-3.22
EczemaWorsen2.64
EpilepsyWorsen3.05
FibromyalgiaWorsen3.04
Functional constipation / chronic idiopathic constipationImproves-3.38
gallstone disease (gsd)Worsen3.05
Generalized anxiety disorderWorsen2.64
GoutWorsen3.6
Graves' diseaseWorsen1.18
Hashimoto's thyroiditisWorsen3.77
Hyperlipidemia (High Blood Fats)Improves-2.91
hypertension (High Blood PressureImproves-4.25
IgA nephropathy (IgAN)Improves-2.64
Inflammatory Bowel DiseaseImproves-2.11
InsomniaWorsen3.05
Liver CirrhosisWorsen4.22
Long COVIDWorsen2.66
ME/CFS with IBSImproves-2.45
ME/CFS without IBSWorsen2.64
Multiple SclerosisWorsen4.12
Multiple system atrophy (MSA)Improves-3.05
Nonalcoholic Fatty Liver Disease (nafld) NonalcoholicImproves-2.45
ObesityWorsen2.31
obsessive-compulsive disorder Improves-3.78
OsteoarthritisWorsen2.64
OsteoporosisImproves-3.05
Parkinson's DiseaseImproves-4.16
PsoriasisWorsen4.04
rheumatoid arthritis (RA),Spondyloarthritis (SpA)Worsen4.6
SchizophreniaImproves-3.05
Sjögren syndromeWorsen0
Sleep ApneaWorsen3.05
Systemic Lupus ErythematosusWorsen2.94
Type 1 DiabetesWorsen3.72
Type 2 DiabetesWorsen1.71
Ulcerative colitisWorsen3.55

Bacteria Impacted

We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.

📓 - direct citation | 👪 - Impacts Parent Taxa | 👶 - Impacts Child Taxa | 🧙 - Inferred
Taxonomy Rank Effect Citations
Bacilli class Increases 📓 Source Study
Clostridia class Increases 📓 Source Study
Erysipelotrichia class Increases 📓 Source Study
Negativicutes class Increases 📓 Source Study
Thermolithobacteria class Increases 📓 Source Study
Tissierellia class Increases 📓 Source Study
Actinomycetaceae family Increases 👪 Source Study
Lachnospiraceae family Increases 📓 Source Study
Acetatifactor genus Increases 👶 Source Study
Acetitomaculum genus Increases 👶 Source Study
Agathobacter genus Increases 👶 Source Study
Anaerobium genus Increases 👶 Source Study
Anaerobutyricum genus Increases 👶 Source Study
Anaerocolumna genus Increases 👶 Source Study
Anaerosporobacter genus Increases 👶 Source Study
Anaerostipes genus Increases 👶 Source Study
Anaerotaenia genus Increases 👶 Source Study
Anaerotignum genus Increases 👶 Source Study
Butyrivibrio genus Increases 👶 Source Study
Catonella genus Increases 👶 Source Study
Cellulosilyticum genus Increases 👶 Source Study
Coprococcus genus Increases 👶 Source Study
Dorea genus Increases 👶 Source Study
Eisenbergiella genus Increases 👶 Source Study
Faecalicatena genus Increases 👶 Source Study
Fusicatenibacter genus Increases 👶 Source Study
Herbinix genus Increases 👶 Source Study
Hespellia genus Increases 👶 Source Study
Johnsonella genus Increases 👶 Source Study
Lachnoanaerobaculum genus Increases 👶 Source Study
Lachnobacterium genus Increases 👶 Source Study
Lachnoclostridium genus Increases 👶 Source Study
Lachnospira genus Increases 👶 Source Study
Lachnotalea genus Increases 👶 Source Study
Marvinbryantia genus Increases 👶 Source Study
Merdimonas genus Increases 👶 Source Study
Mobilitalea genus Increases 👶 Source Study
Moryella genus Increases 👶 Source Study
Murimonas genus Increases 👶 Source Study
Oribacterium genus Increases 👶 Source Study
Parasporobacterium genus Increases 👶 Source Study
Pseudobutyrivibrio genus Increases 👶 Source Study
Robinsoniella genus Increases 👶 Source Study
Roseburia genus Increases 👶 Source Study
Sellimonas genus Increases 👶 Source Study
Shuttleworthia genus Increases 👶 Source Study
Sporobacterium genus Increases 👶 Source Study
Stomatobaculum genus Increases 👶 Source Study
Syntrophococcus genus Increases 👶 Source Study
Tyzzerella genus Increases 👶 Source Study
Blautia genus Increases 📓 Source Study
Schaalia genus Increases 📓 Source Study
[Ruminococcus] gnavus AGR2154 norank Increases 👶 Source Study
[Ruminococcus] gnavus CC55_001C norank Increases 👶 Source Study
[Ruminococcus] gnavus E1 norank Increases 👶 Source Study
[Ruminococcus] gnavus VI-268 norank Increases 👶 Source Study
Blautia luti DSM 14534 norank Increases 👶 Source Study
Blautia obeum ATCC 29174 norank Increases 👶 Source Study
Blautia producta ATCC 27340 norank Increases 👶 Source Study
Blautia schinkii DSM 10518 norank Increases 👶 Source Study
Blautia wexlerae DSM 19850 norank Increases 👶 Source Study
environmental samples norank Increases 👶 Source Study
unclassified Clostridiales norank Increases 👶 Source Study
unclassified Firmicutes sensu stricto norank Increases 👶 Source Study
unclassified Halanaerobiales norank Increases 👶 Source Study
unclassified Lachnospiraceae norank Increases 👶 Source Study
unclassified Thermoanaerobacterales norank Increases 👶 Source Study
environmental samples norank Increases 📓 Source Study
Clostridiales order Increases 📓 Source Study
Halanaerobiales order Increases 📓 Source Study
Thermoanaerobacterales order Increases 📓 Source Study
Firmicutes phylum Increases 📓 Source Study
Actinomyces canis species Increases 👶 Source Study
Actinomyces cardiffensis species Increases 👶 Source Study
Actinomyces georgiae species Increases 👶 Source Study
Actinomyces hyovaginalis species Increases 👶 Source Study
Actinomyces meyeri species Increases 👶 Source Study
Actinomyces naturae species Increases 👶 Source Study
Actinomyces odontolyticus species Increases 👶 Source Study
Actinomyces radingae species Increases 👶 Source Study
Actinomyces suimastitidis species Increases 👶 Source Study
Actinomyces turicensis species Increases 👶 Source Study
Actinomyces vaccimaxillae species Increases 👶 Source Study
Blautia massiliensis species Increases 👶 Source Study
Blautia sp. species Increases 👶 Source Study
Blautia sp. KCTC 15426 species Increases 👶 Source Study
Blautia sp. KLE 1732 species Increases 👶 Source Study
Blautia sp. MC_32 species Increases 👶 Source Study
environmental samples species Increases 👶 Source Study
Firmicutes bacterium CAG:110 species Increases 👶 Source Study
Firmicutes bacterium CAG:145 species Increases 👶 Source Study
Firmicutes bacterium CAG:170 species Increases 👶 Source Study
Firmicutes bacterium CAG:24 species Increases 👶 Source Study
Firmicutes bacterium CAG:313 species Increases 👶 Source Study
Firmicutes bacterium CAG:41 species Increases 👶 Source Study
Firmicutes bacterium CAG:65 species Increases 👶 Source Study
Firmicutes bacterium CAG:83 species Increases 👶 Source Study
Firmicutes bacterium enrichment culture species Increases 👶 Source Study
[Ruminococcus] gnavus species Increases 📓 Source Study
[Ruminococcus] torques species Increases 📓 Source Study
Blautia coccoides species Increases 📓 Source Study
Blautia faecis species Increases 📓 Source Study
Blautia glucerasea species Increases 📓 Source Study
Blautia hansenii species Increases 📓 Source Study
Blautia hydrogenotrophica species Increases 📓 Source Study
Blautia luti species Increases 📓 Source Study
Blautia obeum species Increases 📓 Source Study
Blautia producta species Increases 📓 Source Study
Blautia schinkii species Increases 📓 Source Study
Blautia sp. Ser5 species Increases 📓 Source Study
Blautia sp. Ser8 species Increases 📓 Source Study
Blautia sp. YHC-4 species Increases 📓 Source Study
Blautia stercoris species Increases 📓 Source Study
Blautia wexlerae species Increases 📓 Source Study

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This is an Academic site. It generates theoretical models of what may benefit a specific microbiome results.