Modelled supplements for Age-Related Macular Degeneration and Glaucoma

Conventional Beliefs

  1. Antioxidant Vitamins and Minerals: Certain vitamins and minerals with antioxidant properties have been investigated for their potential to support eye health:

    • Vitamin C, E, and Zinc: These antioxidants may help protect the eyes from oxidative stress. Some studies, like the Age-Related Eye Disease Study (AREDS), have suggested that a specific combination of vitamins and minerals (vitamin C, vitamin E, zinc, copper, and beta-carotene) may slow the progression of AMD in individuals at risk of advanced AMD. However, beta-carotene supplementation is not recommended for smokers due to potential health risks.

    • Lutein and Zeaxanthin: These carotenoids are found in high concentrations in the macula (the central part of the retina) and are believed to protect against AMD. Some studies suggest that lutein and zeaxanthin supplementation may have a protective effect against AMD progression.

  2. Omega-3 Fatty Acids: Some research has suggested that omega-3 fatty acids, found in fish oil supplements or in foods like fatty fish, may have a potential role in supporting eye health and reducing the risk of AMD. However, evidence supporting their effectiveness is not conclusive.

  3. Ginkgo Biloba: Ginkgo biloba is an herbal supplement that has been studied for its potential to improve blood flow and protect against oxidative damage in the eyes. Some research has explored its use in glaucoma, but its efficacy remains uncertain, and more evidence is needed.

  4. Probiotics: The role of probiotics in eye health, particularly in conditions like AMD and glaucoma, is not well-established. While maintaining overall health through a balanced gut microbiota might indirectly support general well-being, there's limited evidence linking probiotics directly to improved eye health or the treatment of AMD or glaucoma.

For an explanation of how this is generated, see this post

All suggestions from this page should be reviewed by your medical professionals. These are based on modelling and not clinical studies.

Based on family and lower taxonomy ranks (genus,species,strains) reported in studies, the list is here

Net Impact Modifier Citations
4.1 pseudo-cereals {amaranth,quinoa, taro,buckwheat}   πŸ“š
2.8 Fagopyrum esculentum {Buckwheat}   πŸ“š
2.7 Mixture of Vitamin B? {B Vitamins}   πŸ“š
2.2 barley   πŸ“πŸ½οΈ Dosages πŸ“š
2 Echinacea Moench {Echinacea}   πŸ“πŸ½οΈ Dosages πŸ“š
2 Abelmoschus {Okra}   πŸ“š
1.9 colostrum   πŸ“š
1.9 Zingiber officinale Roscoe {ginger}   πŸ“š
1.8 Traditional Mediterranean diet {Mediterranean diet}   πŸ“š
1.8 amaranthus {amaranth}   πŸ“š
1.7 high-fat diets   πŸ“š
1.6 lard   πŸ“š
1.5 Brassica oleracea var. italica {Broccoli}   πŸ“š
1.4 Lacticaseibacillus paracasei shirota {Yakult}   πŸ“πŸ½οΈ Dosages πŸ“š
1.4 vitamin b2,Riboflavin   πŸ“πŸ½οΈ Dosages πŸ“š
1.4 a-Gluco-oligosaccharides {GOS}   πŸ“š
1.4 Citrus polymethoxyflavone {Nobiletin (oranges and lemons)}   πŸ“š
1.3 Sauerkraut   πŸ“š
1.3 Amorphophallus konjac {Konjaku flour}   πŸ“š
1.3 lactobacillus salivarius   πŸ“πŸ½οΈ Dosages πŸ“š
1.2 Phyllanthus emblica {Chinese gall}   πŸ“š
1.1 Vitamin B1,thiamine hydrochloride   πŸ“πŸ½οΈ Dosages πŸ“š
1.1 Psyllium (Plantago Ovata Husk)   πŸ“πŸ½οΈ Dosages πŸ“š
1 quinoa   πŸ“š
1 dimethyl fumarate {Fumarate}   πŸ“š
0.9 cranberry bean flour   πŸ“š
0.9 Lentilactobacillus kefiri {Kefibios}   πŸ“š
0.9 Hypericum perforatum {St. John's Wort}   πŸ“š
0.9 4-hydroxyphenyl-beta-D-glucopyranoside {Arbutin}   πŸ“πŸ½οΈ Dosages πŸ“š
0.9 Sorghum {Broomcorn}   πŸ“š
0.9 Slippery Elm   πŸ“š
0.9 Prunus mume {Umeboshi}   πŸ“š
0.9 Piper nigrum {black pepper}   πŸ“š
0.9 Carrageenans {Carrageenan}   πŸ“š
0.8 rice bran   πŸ“š
0.8 bacillus amyloliquefaciens (probiotic)   πŸ“πŸ½οΈ Dosages πŸ“š
0.8 vegetable/fruit juice-based diets   πŸ“š
0.8 acetic acid   πŸ“š
0.7 bifidobacterium adolescentis,   πŸ“πŸ½οΈ Dosages πŸ“š
0.7 low fiber diet   πŸ“š
0.6 bifidobacterium animalis lactis   πŸ“πŸ½οΈ Dosages πŸ“š
0.6 bacillus coagulans   πŸ“πŸ½οΈ Dosages πŸ“š
0.6 loperamide hydrochloride,(prescription)   πŸ“š
0.6 kefir   πŸ“š
0.6 Bifidobacterium animalis   πŸ“š
0.6 Pleurotus ostreatus {Oyster mushroom}   πŸ“š
0.6 Bacteriophages LH01,T4D,LL12,LL5 {PreforPro}   πŸ“š
0.6 brassica juncea   πŸ“š
0.6 bifidobacterium lactis,streptococcus thermophilus probiotic   πŸ“š
0.5 xylooligosaccharide   πŸ“πŸ½οΈ Dosages πŸ“š
0.5 walnuts   πŸ“πŸ½οΈ Dosages πŸ“š
-0.5 thyme (thymol, thyme oil)   πŸ“š
-0.5 ß-glucan   πŸ“πŸ½οΈ Dosages πŸ“š
-0.5 white button mushrooms   πŸ“š
-0.5 chicken   πŸ“š
-0.5 magnesium   πŸ“πŸ½οΈ Dosages πŸ“š
-0.5 laminaria hyperborea   πŸ“š
-0.5 low carbohydrate diet   πŸ“š
-0.5 avocado peel   πŸ“š
-0.5 Astragalus   πŸ“š
-0.5 Tea tree   πŸ“š
-0.5 Crocus sativus {Saffron}   πŸ“š
-0.5 fucoidan   πŸ“πŸ½οΈ Dosages πŸ“š
-0.5 Dihydroquercetin {Taxifolin}   πŸ“πŸ½οΈ Dosages πŸ“š
-0.5 Fruits (Cooked)   πŸ“š
-0.5 N-acetylglucosamine {Glucosamine (GS)}   πŸ“š
-0.6 Peanut   πŸ“š
-0.6 Brazilian nuts   πŸ“š
-0.6 lactobacillus rhamnosus gg   πŸ“πŸ½οΈ Dosages πŸ“š
-0.6 Limosilactobacillus fermentum (probiotic)   πŸ“πŸ½οΈ Dosages πŸ“š
-0.6 enterococcus durans {Streptococcus durans}   πŸ“š
-0.6 Epicatechin {Green tea polyphenol}   πŸ“š
-0.6 Ginkgo biloba {Ginkgo}   πŸ“πŸ½οΈ Dosages πŸ“š
-0.6 Conjugated Linoleic Acid {CLA}   πŸ“š
-0.6 Vitamin C (ascorbic acid)   πŸ“πŸ½οΈ Dosages πŸ“š
-0.6 wheat   πŸ“š
-0.7 diosmin {diosmin}   πŸ“πŸ½οΈ Dosages πŸ“š
-0.7 vitamin a   πŸ“πŸ½οΈ Dosages πŸ“š
-0.7 tomato powder   πŸ“š
-0.7 Curcumin   πŸ“πŸ½οΈ Dosages πŸ“š
-0.7 terpenophenolics {cannabinoids}   πŸ“š
-0.7 bifidobacterium bifidum   πŸ“πŸ½οΈ Dosages πŸ“š
-0.7 cellulose   πŸ“š
-0.7 Zea mays {maize}   πŸ“š
-0.7 Pulses, Beans   πŸ“š
-0.7 Persimmon   πŸ“š
-0.7 Lycopene {Glucosamine (GS)}   πŸ“πŸ½οΈ Dosages πŸ“š
-0.7 pediococcus acidilactic {RBB9 PEDIOCOCCUS ACIDILACTI}   πŸ“š
-0.7 Curcuma amada {Mango ginger}   πŸ“š
-0.8 Quercetin-3-O-rutinoside {Rutin}   πŸ“πŸ½οΈ Dosages πŸ“š
-0.8 Gamma-Aminobutyric Acid {GABA}   πŸ“πŸ½οΈ Dosages πŸ“š
-0.8 chlorhexidine   πŸ“š
-0.8 vitamin B3,niacin   πŸ“πŸ½οΈ Dosages πŸ“š
-0.8 omeprazole,(prescription)   πŸ“š
-0.9 omega-3 fatty acids   πŸ“πŸ½οΈ Dosages πŸ“š
-0.9 melatonin supplement   πŸ“πŸ½οΈ Dosages πŸ“š
-0.9 l-proline   πŸ“š
-0.9 Cichorium intybus {Chicory}   πŸ“πŸ½οΈ Dosages πŸ“š
-0.9 bifidobacterium catenulatum,   πŸ“š
-0.9 bifidobacterium longum bb536   πŸ“š
-0.9 black raspberries   πŸ“πŸ½οΈ Dosages πŸ“š
-0.9 Olive Oil   πŸ“š
-1 Boron (Organic Source)   πŸ“š
-1 Rhodiola rosea {Rosavin}   πŸ“πŸ½οΈ Dosages πŸ“š
-1 Tryptophan   πŸ“πŸ½οΈ Dosages πŸ“š
-1 Morinda citrifolia {Noni}   πŸ“πŸ½οΈ Dosages πŸ“š
-1 Aloe vera {True Aloe}   πŸ“š
-1 Ethyl alcohol {Grain alcohol}   πŸ“š
-1 ketogenic diet   πŸ“š
-1 High glycemic diet {High-sugar diet (HSD)}   πŸ“š
-1 l-arginine   πŸ“πŸ½οΈ Dosages πŸ“š
-1 Prunus avium {Cherry}   πŸ“š
-1 red wine polyphenols   πŸ“πŸ½οΈ Dosages πŸ“š
-1 resveratrol-pterostilbene {grapes, blueberries}   πŸ“πŸ½οΈ Dosages πŸ“š
-1.1 sodium butyrate   πŸ“š
-1.1 Vsl#3 {Visibiome}   πŸ“š
-1.1 zinc   πŸ“πŸ½οΈ Dosages πŸ“š
-1.1 Vitamin B-12   πŸ“πŸ½οΈ Dosages πŸ“š
-1.1 High-amylose maize starch {HAMS}   πŸ“š
-1.1 Rhubarb x Peony {Rhubarb Peony Decoction}   πŸ“š
-1.1 Whole Cow milk {Whole Milk}   πŸ“š
-1.1 enterococcus faecium (probiotic)   πŸ“πŸ½οΈ Dosages πŸ“š
-1.1 brown algae   πŸ“š
-1.1 Perilla frutescens {Perilla}   πŸ“πŸ½οΈ Dosages πŸ“š
-1.1 almonds/ almond skins   πŸ“πŸ½οΈ Dosages πŸ“š
-1.1 Citrus aurantiifolia {Lime}   πŸ“š
-1.1 Silybum marianum {milk thistle}   πŸ“πŸ½οΈ Dosages πŸ“š
-1.1 Citrus limon {Lemon}   πŸ“š
-1.1 potatoes   πŸ“š
-1.1 Bifidobacterium breve {B. breve}   πŸ“πŸ½οΈ Dosages πŸ“š
-1.1 Cucurbita pepo {Pumpkin}   πŸ“š
-1.2 Apigenin   πŸ“š
-1.2 A2 Milk   πŸ“š
-1.2 Beta vulgaris {Beet}   πŸ“š
-1.2 3,5,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one {kaempferol}   πŸ“š
-1.2 ibuprofen   πŸ“š
-1.2 lactobacillus reuteri   πŸ“πŸ½οΈ Dosages πŸ“š
-1.2 Human milk oligosaccharides (prebiotic, Holigos, Stachyose)   πŸ“πŸ½οΈ Dosages πŸ“š
-1.3 oolong teas   πŸ“š
-1.3 bifidobacterium longum,lactobacillus helveticus   πŸ“š
-1.3 Camellia Linnaeus {camellia}   πŸ“š
-1.3 Sodium alginate   πŸ“πŸ½οΈ Dosages πŸ“š
-1.4 Pulvis ledebouriellae compositae {Bofutsushosan}   πŸ“š
-1.4 glycine   πŸ“πŸ½οΈ Dosages πŸ“š
-1.4 Ursolic acid   πŸ“š
-1.4 2-(3,4-Dihydroxyphenyl)-3,7-dihydroxychromen-4-one {Fisetin}   πŸ“πŸ½οΈ Dosages πŸ“š
-1.4 saccharomyces boulardii   πŸ“πŸ½οΈ Dosages πŸ“š
-1.4 lactobacillus casei   πŸ“πŸ½οΈ Dosages πŸ“š
-1.4 arabinogalactan {arabinogalactan}   πŸ“πŸ½οΈ Dosages πŸ“š
-1.4 garlic (allium sativum)   πŸ“πŸ½οΈ Dosages πŸ“š
-1.4 bifidobacterium longum   πŸ“πŸ½οΈ Dosages πŸ“š
-1.5 bacillus   πŸ“š
-1.5 aspergillus oryzae {koji}   πŸ“š
-1.5 whey   πŸ“πŸ½οΈ Dosages πŸ“š
-1.5 cruciferous vegetables (broccoli cabbage)   πŸ“š
-1.5 Goji (berry,juice)   πŸ“š
-1.5 Alpha-Ketoglutarate   πŸ“š
-1.5 Panax ... {Ginseng}   πŸ“πŸ½οΈ Dosages πŸ“š
-1.5 fluorine   πŸ“š
-1.6 Tudca   πŸ“πŸ½οΈ Dosages πŸ“š
-1.6 Lithium carbonate {Lithium}   πŸ“š
-1.6 Lactiplantibacillus pentosus {L. pentosus}   πŸ“š
-1.6 Nutmeg   πŸ“š
-1.6 Laurus nobilis {Bay Leaf}   πŸ“š
-1.6 eugenol {Eugenic acid}   πŸ“š
-1.6 low protein diet   πŸ“š
-1.6 quercetin   πŸ“πŸ½οΈ Dosages πŸ“š
-1.6 Ocimum basilicum {Basil}   πŸ“š
-1.7 salt (sodium chloride)   πŸ“š
-1.8 Bifidobacterium animalis subsp. lactis BB-12 {bifidobacterium lactis bb12}   πŸ“πŸ½οΈ Dosages πŸ“š
-1.8 fasting   πŸ“š
-1.8 Moringa Oleifera   πŸ“š
-1.9 Pediococcus pentosaceus   πŸ“š
-1.9 Vitamin E   πŸ“πŸ½οΈ Dosages πŸ“š
-1.9 fructo-oligosaccharides   πŸ“πŸ½οΈ Dosages πŸ“š
-2 red wine   πŸ“πŸ½οΈ Dosages πŸ“š
-2 lactobacillus helveticus,lactobacillus rhamnosus   πŸ“š
-2 vegetarians   πŸ“š
-2 pectin   πŸ“š
-2 soy   πŸ“πŸ½οΈ Dosages πŸ“š
-2 Lonicera periclymenum {Epazote}   πŸ“š
-2 Dendrobium officinale Kimura {Tiepishihu}   πŸ“š
-2 L-Theanine {Theanine}   πŸ“š
-2 Lion's Mane Mushroom   πŸ“š
-2.1 theabrownin {theabrownin}   πŸ“š
-2.1 Taraxacum officinale {Dandelion}   πŸ“š
-2.1 Vaccinium myrtillus {Bilberry}   πŸ“πŸ½οΈ Dosages πŸ“š
-2.1 Guaiacol (polyphenol)   πŸ“š
-2.1 naringenin(grapefruit) (Flavonoid)   πŸ“š
-2.2 Cacao   πŸ“πŸ½οΈ Dosages πŸ“š
-2.2 Menaquinone K2 {Vitamin K}   πŸ“πŸ½οΈ Dosages πŸ“š
-2.4 partially hydrolysed guar gum   πŸ“š
-2.5 Ganoderma lucidum {Reishi}   πŸ“š
-2.5 banana   πŸ“š
-2.6 vitamin d   πŸ“πŸ½οΈ Dosages πŸ“š
-2.7 Cinnamomum zeylanicum {Ceylon Cinnamon}   πŸ“πŸ½οΈ Dosages πŸ“š
-2.8 bacillus subtilis   πŸ“πŸ½οΈ Dosages πŸ“š
-2.8 Linum usitatissimum {Flaxseed}   πŸ“πŸ½οΈ Dosages πŸ“š
-2.8 yogurt   πŸ“š
-2.9 fat   πŸ“š
-3 Phaseolus vulgaris {Boston bean}   πŸ“š
-3 quebracho   πŸ“š
-3.1 bacillus,lactobacillus,streptococcus,saccharomyces probiotic   πŸ“š
-3.4 polyphenols   πŸ“πŸ½οΈ Dosages πŸ“š
-3.6 Chrysanthemum × morifolium {Chrysanthemum}   πŸ“š
-3.6 oligosaccharides {oligosaccharides}   πŸ“š
-3.6 Dextrin   πŸ“πŸ½οΈ Dosages πŸ“š
-3.8 Honey {Honey }   πŸ“πŸ½οΈ Dosages πŸ“š
-3.8 Xanthohumol   πŸ“š
-3.8 Pentadigalloylglucose {Tannic Acid}   πŸ“š
-3.9 Grape Polyphenols {Grape Flavonoids}   πŸ“š
-3.9 grapes   πŸ“š
-4.2 Capsicum annuum {Peppers} {Cayenne Pepper, Hot Pepper}   πŸ“š
-4.4 Bovine Milk Products {Dairy}   πŸ“š
-4.6 inulin   πŸ“πŸ½οΈ Dosages πŸ“š
-4.8 lactobacillus plantarum   πŸ“πŸ½οΈ Dosages πŸ“š
-5 tea   πŸ“š
-5.6 resistant starch   πŸ“š
-6.2 bifidobacterium   πŸ“š
-6.3 Dietary Approaches to Stop Hypertension {DASH}   πŸ“š
-7 Caffeine   πŸ“š
-7.5 Coffee   πŸ“š
-7.5 Cola (w/ aspartame)   πŸ“š
-10.1 fruit/legume fibre   πŸ“š
-10.1 high fruit intake   πŸ“š
-11.1 fruit   πŸ“š
-11.7 dietary fiber   πŸ“š
-11.7 High-fibre diet {Whole food diet}   πŸ“š
-11.7 Fiber, total dietary   πŸ“š

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