Probiotics: Some individuals with chronic Lyme disease might consider probiotics to support gut health. Antibiotic treatments for Lyme disease may disrupt the balance of gut microbiota, and probiotics might help restore a healthy gut flora. However, evidence supporting their use specifically for chronic Lyme disease is lacking.
Vitamins and Minerals: Individuals with chronic Lyme disease might have specific nutritional needs or deficiencies due to factors such as compromised immune function or chronic inflammation. Supplements such as vitamins (e.g., vitamin D, B vitamins) or minerals (like magnesium or zinc) might be considered to address identified deficiencies. However, the use of supplements should be guided by healthcare professionals.
Omega-3 Fatty Acids: Omega-3 supplements containing EPA and DHA have anti-inflammatory properties and may support overall health. Some individuals might consider omega-3 supplementation for potential anti-inflammatory effects, although evidence supporting their use specifically for chronic Lyme disease is limited.
Herbal Supplements: Some individuals with chronic Lyme disease might explore herbal supplements such as Japanese knotweed, cat's claw, or garlic, among others. These herbs are believed by some to have antimicrobial or immune-modulating properties. However, the evidence supporting their effectiveness in treating chronic Lyme disease is limited and requires further research.
All suggestions from this page should be reviewed by your medical professionals. These are based on modelling and not clinical studies.
Based on family and lower taxonomy ranks (genus,species,strains) reported in studies,
the list is here
Net Impact |
Modifier |
Citations |
3.4
|
Vitamin B9,folic acid
ππ½οΈ Dosages
|
π
|
3.2
|
bifidobacterium longum bb536 (probiotics)
|
π
|
3.1
|
gluten-free diet
|
π
|
2.7
|
symbioflor 2 e.coli probiotics
|
π
|
2.5
|
vitamin a
ππ½οΈ Dosages
|
π
|
2.2
|
cannabinoids
|
π
|
2
|
Tudca
ππ½οΈ Dosages
|
π
|
2
|
lauric acid(fatty acid in coconut oil,in palm kernel oil,)
|
π
|
1.9
|
fructo-oligosaccharides (prebiotic)
ππ½οΈ Dosages
|
π
|
1.8
|
Cacao
ππ½οΈ Dosages
|
π
|
1.8
|
whole-grain barley
ππ½οΈ Dosages
|
π
|
1.7
|
grape polyphenols
|
π
|
1.6
|
green-lipped mussel
|
π
|
1.6
|
carob
|
π
|
1.5
|
Konjaku flour
|
π
|
1.5
|
Grapefruit seed extract
|
π
|
1.5
|
Hesperidin (polyphenol)
ππ½οΈ Dosages
|
π
|
1.4
|
Shen Ling Bai Zhu San
|
π
|
1.4
|
alcoholic beverages
|
π
|
1.3
|
Apple skin
|
π
|
1.3
|
bifidobacterium lactis,streptococcus thermophilus probiotic
|
π
|
1.3
|
sorghum
|
π
|
1.3
|
fruit/legume fibre
|
π
|
1.3
|
marijuana
|
π
|
1.3
|
dates
|
π
|
1.3
|
lactobacillus kefiri (NOT KEFIR)
|
π
|
1.2
|
low-fat high-complex carbohydrate diet
|
π
|
1.2
|
high-protein diet
|
π
|
1.2
|
bean
|
π
|
1.2
|
low-fat diets
|
π
|
1.2
|
Lithium
|
π
|
1.1
|
Nicotine, Nicotine Patch
|
π
|
1.1
|
beef
|
π
|
1.1
|
mannooligosaccharide (prebiotic)
ππ½οΈ Dosages
|
π
|
1.1
|
lactobacillus sakei (probiotics)
|
π
|
1.1
|
General Biotics Equilibrium
|
π
|
1.1
|
galla rhois
|
π
|
1.1
|
cvs maximum strength probiotic
|
π
|
1.1
|
naringenin(grapefruit) (Flavonoid)
|
π
|
1.1
|
Vitamin B1,thiamine hydrochloride
ππ½οΈ Dosages
|
π
|
1.1
|
colinfant e.coli probiotics
|
π
|
1.1
|
luteolin (flavonoid)
ππ½οΈ Dosages
|
π
|
1
|
N-Acetyl Cysteine (NAC),
ππ½οΈ Dosages
|
π
|
1
|
propolis(bee's glue)
|
π
|
1
|
lactobacillus gasseri (probiotics)
ππ½οΈ Dosages
|
π
|
1
|
ginger
|
π
|
1
|
chamaemelum nobile,chamomile
|
π
|
1
|
acetic acid
|
π
|
1
|
bifidobacterium breve (probiotic)
ππ½οΈ Dosages
|
π
|
1
|
Acai
|
π
|
1
|
catechins (from tea/wine)
|
π
|
1
|
Citric acid
|
π
|
1
|
Clove
|
π
|
1
|
Coffee
|
π
|
1
|
Cola (w/ aspartame)
|
π
|
1
|
Bay Leaf
|
π
|
1
|
Bilberry
ππ½οΈ Dosages
|
π
|
1
|
Boldo
|
π
|
1
|
Red Cabbage
|
π
|
1
|
Caffeine
|
π
|
1
|
Caramel color
|
π
|
1
|
Caraway
|
π
|
1
|
Cardamom
|
π
|
1
|
Nutmeg
|
π
|
1
|
Onion
|
π
|
1
|
Papaya leaf
|
π
|
1
|
Papaya seed
|
π
|
1
|
Parsley
|
π
|
1
|
Celery Seed
|
π
|
1
|
Cilantro
|
π
|
1
|
Galangal
|
π
|
1
|
Goldenseal
|
π
|
1
|
Soy sauce
|
π
|
1
|
Sriracha sauce
|
π
|
1
|
Tabasco sauce
|
π
|
1
|
Tapatio
|
π
|
1
|
Tea tree
|
π
|
1
|
Trigonelline (found in Coffee)
|
π
|
1
|
Turmeric
ππ½οΈ Dosages
|
π
|
1
|
Hibiscus
|
π
|
1
|
Honeysuckle
|
π
|
1
|
Hops
|
π
|
1
|
Horseradish
|
π
|
1
|
Kimchi
|
π
|
1
|
Lemon Balm
|
π
|
1
|
Lemon peel
|
π
|
1
|
Lemongrass
|
π
|
1
|
Lime
|
π
|
1
|
Cranberry
|
π
|
1
|
Cumin
|
π
|
1
|
Dandelion
|
π
|
1
|
Echinacea
ππ½οΈ Dosages
|
π
|
1
|
Elderberry
|
π
|
1
|
Epazote
|
π
|
1
|
Eucalyptus
|
π
|
1
|
Fernet
|
π
|
1
|
noni
ππ½οΈ Dosages
|
π
|
1
|
Taxifolin
ππ½οΈ Dosages
|
π
|
1
|
Pineapple
|
π
|
1
|
Piperine
|
π
|
1
|
Pumpkin seed
|
π
|
1
|
Mustard seed extract
|
π
|
1
|
Mustard yellow
|
π
|
1
|
Uva Ursi
|
π
|
1
|
Vegemite
|
π
|
0.9
|
fluorine
|
π
|
0.9
|
Methionine
ππ½οΈ Dosages
|
π
|
0.9
|
chitooligosaccharides (prebiotic)
ππ½οΈ Dosages
|
π
|
0.9
|
low carbohydrate diet
|
π
|
0.9
|
diosmin,(polyphenol)
ππ½οΈ Dosages
|
π
|
0.8
|
lactobacillus salivarius (probiotics)
ππ½οΈ Dosages
|
π
|
0.7
|
Rutin
ππ½οΈ Dosages
|
π
|
0.6
|
eugenol (from clove oil, nutmeg, cinnamon, basil,bay leaf.)
|
π
|
0.6
|
anise
ππ½οΈ Dosages
|
π
|
0.6
|
bifidobacterium pseudocatenulatum,(probiotics)
|
π
|
0.6
|
rhubarb
|
π
|
0.5
|
Cheese
|
π
|
0.5
|
chlorine
|
π
|
-0.6
|
Far infrared Sauna
|
π
|
-0.6
|
Kale
|
π
|
-0.6
|
Sulforaphane,1-Isothiocyanato-4-(methanesulfinyl)butane,C6H11NOS2
|
π
|
-0.6
|
Vitamin C (ascorbic acid)
ππ½οΈ Dosages
|
π
|
-0.6
|
red alga Laurencia tristicha
|
π
|
-0.6
|
Vitamin B-12
ππ½οΈ Dosages
|
π
|
-0.6
|
carboxymethyl cellulose (prebiotic)
|
π
|
-0.7
|
ketogenic diet
|
π
|
-0.7
|
high sugar diet
|
π
|
-0.7
|
salt (sodium chloride)
|
π
|
-0.7
|
Ursolic acid
|
π
|
-0.8
|
candida albicans (prescription)
|
π
|
-0.9
|
coriander oil
|
π
|
-0.9
|
lactobacillus casei shirota (probiotics)
ππ½οΈ Dosages
|
π
|
-0.9
|
cylicodiscus gabunensis (mimosaceae)
|
π
|
-0.9
|
red wine
ππ½οΈ Dosages
|
π
|
-0.9
|
cherry
|
π
|
-0.9
|
bacillus pumilus
|
π
|
-0.9
|
yogurt
|
π
|
-0.9
|
chicken
|
π
|
-0.9
|
rye
|
π
|
-0.9
|
fenugreek
|
π
|
-0.9
|
trachyspermum ammi, Ajwain
|
π
|
-0.9
|
hou-po-da-huang-tang
|
π
|
-0.9
|
Soymilk
|
π
|
-1
|
Lentilactobacillus buchneri
|
π
|
-1
|
bifidobacterium bifidum (probiotics)
ππ½οΈ Dosages
|
π
|
-1
|
quebracho
|
π
|
-1.1
|
punicic acid
|
π
|
-1.1
|
nobiletin
|
π
|
-1.2
|
Fisetin
ππ½οΈ Dosages
|
π
|
-1.2
|
camellia
|
π
|
-1.2
|
Reishi Mushroom
ππ½οΈ Dosages
|
π
|
-1.2
|
Sauerkraut
|
π
|
-1.2
|
Silver
|
π
|
-1.2
|
Kaempferol
|
π
|
-1.2
|
Fish Sauce
|
π
|
-1.2
|
Manuka Honey
ππ½οΈ Dosages
|
π
|
-1.2
|
Miso
|
π
|
-1.2
|
Umcka
|
π
|
-1.2
|
Pickle juice
|
π
|
-1.2
|
bacillus amyloliquefaciens (probiotic)
ππ½οΈ Dosages
|
π
|
-1.2
|
lactobacillus delbrueckii bulgaricus,bifidobacterium bifidum,enterococcus faecium,candida pintolopesii,aspergillus oryzae (probiotics)
|
π
|
-1.2
|
Goji (berry,juice)
|
π
|
-1.2
|
Aloe
|
π
|
-1.2
|
pediococcus acidilactic (probiotic)
|
π
|
-1.2
|
mulberry fruit polysaccharide
|
π
|
-1.2
|
Carrot (juice)
|
π
|
-1.2
|
Cottage Cheese
|
π
|
-1.2
|
Cayenne
|
π
|
-1.2
|
oats
|
π
|
-1.2
|
partially hydrolysed guar gum,fructo-oligosaccharides (prebiotic)
|
π
|
-1.2
|
kombucha
|
π
|
-1.2
|
iron
ππ½οΈ Dosages
|
π
|
-1.2
|
grape seed extract
ππ½οΈ Dosages
|
π
|
-1.2
|
coptis chinensis, Chinese goldthread
|
π
|
-1.3
|
dietary fiber
|
π
|
-1.3
|
bioflorin,enterococcus faecium sf 68,(probiotics)
|
π
|
-1.3
|
hypericin, St. John's Wort
|
π
|
-1.3
|
lactobacillus helveticus,lactobacillus rhamnosus (probiotics)
|
π
|
-1.3
|
lemon oil
|
π
|
-1.3
|
tabebuia impetiginosa (taheebo) bark
|
π
|
-1.3
|
vitex negundo (herb)
|
π
|
-1.3
|
rosehip tea
|
π
|
-1.3
|
pomegranate blossom tea
|
π
|
-1.3
|
xylaria hypoxylon (fungi)
|
π
|
-1.3
|
laser trilobum l.,kefe cumin
|
π
|
-1.3
|
schinus molle (herb)
|
π
|
-1.3
|
sesuvium portulacastrum herb
|
π
|
-1.3
|
red chiles (Capsicum)
|
π
|
-1.3
|
rosa canina
|
π
|
-1.3
|
persimmon tannin
|
π
|
-1.3
|
whey
ππ½οΈ Dosages
|
π
|
-1.3
|
high red meat
|
π
|
-1.3
|
papaya
|
π
|
-1.3
|
bacillus,lactobacillus,streptococcus,saccharomyces probiotic
|
π
|
-1.3
|
partially hydrolyzed guar gum
ππ½οΈ Dosages
|
π
|
-1.4
|
high-fat diets
|
π
|
-1.4
|
ß-glucan
ππ½οΈ Dosages
|
π
|
-1.4
|
lactobacillus casei (probiotics)
ππ½οΈ Dosages
|
π
|
-1.4
|
fish oil
ππ½οΈ Dosages
|
π
|
-1.4
|
Dangshen
|
π
|
-1.5
|
fat
|
π
|
-1.5
|
almonds/ almond skins
ππ½οΈ Dosages
|
π
|
-1.5
|
bacillus (probiotics)
|
π
|
-1.5
|
white button mushrooms
|
π
|
-1.5
|
whole grain,bran
|
π
|
-1.5
|
Guaiacol (polyphenol)
|
π
|
-1.5
|
polygonatum kingianum(Orange Flower Solomon's Seal.)
|
π
|
-1.5
|
Conjugated Linoleic Acid
|
π
|
-1.6
|
propionate
|
π
|
-1.6
|
Astragalus
|
π
|
-1.6
|
potatoes
|
π
|
-1.6
|
rice bran
|
π
|
-1.6
|
Oyster Mushroom
|
π
|
-1.6
|
Cinnamaldehyde
|
π
|
-1.6
|
slow digestible carbohydrates
|
π
|
-1.6
|
refined wheat breads
|
π
|
-1.6
|
quercetin
ππ½οΈ Dosages
|
π
|
-1.6
|
tea
|
π
|
-1.6
|
blackcurrant
|
π
|
-1.6
|
hypocaloric hyperproteic diet
|
π
|
-1.6
|
high beef diet
|
π
|
-1.6
|
lard
|
π
|
-1.7
|
lactobacillus plantarum,xylooligosaccharides,(prebiotic) (probiotics)
|
π
|
-1.7
|
neem
ππ½οΈ Dosages
|
π
|
-1.7
|
Citrus Fruit Extract
|
π
|
-1.8
|
emblica officinalis
|
π
|
-1.8
|
buckwheat
|
π
|
-1.8
|
nigella sativa seed (black cumin)
ππ½οΈ Dosages
|
π
|
-1.8
|
enterococcus faecium (probiotic)
ππ½οΈ Dosages
|
π
|
-1.9
|
Umeboshi (Japanese Apricot or Prunus mume )
|
π
|
-1.9
|
lactobacillus rhamnosus (probiotics)
ππ½οΈ Dosages
|
π
|
-2
|
mutaflor escherichia coli nissle 1917 (probiotics)
ππ½οΈ Dosages
|
π
|
-2
|
bacillus licheniformis,(probiotics)
ππ½οΈ Dosages
|
π
|
-2
|
animal-based diet
|
π
|
-2
|
broccoli
|
π
|
-2
|
cranberry bean flour
|
π
|
-2
|
plantago asiatica l.
|
π
|
-2.1
|
Spearmint(mentha spicata)
|
π
|
-2.1
|
foeniculum vulgare,fennel
|
π
|
-2.2
|
bacillus subtilis (probiotics)
ππ½οΈ Dosages
|
π
|
-2.2
|
blueberry
|
π
|
-2.2
|
syzygium aromaticum (clove)
|
π
|
-2.2
|
Lactobacillus Johnsonii (probiotic)
ππ½οΈ Dosages
|
π
|
-2.2
|
Baicalin
|
π
|
-2.3
|
Pork
|
π
|
-2.3
|
Slippery Elm
|
π
|
-2.3
|
Glucomannan
ππ½οΈ Dosages
|
π
|
-2.3
|
laminaria digitata,oarweed - seaweed
|
π
|
-2.4
|
rosmarinus officinalis,rosemary
|
π
|
-2.5
|
resistant starch
|
π
|
-2.5
|
methionine-choline-deficient (MCD) diet
|
π
|
-2.6
|
walnuts
ππ½οΈ Dosages
|
π
|
-2.6
|
zinc
ππ½οΈ Dosages
|
π
|
-2.6
|
barley,oat
|
π
|
-2.8
|
Vitamin E
ππ½οΈ Dosages
|
π
|
-2.8
|
Bofutsushosan
|
π
|
-2.8
|
banana
|
π
|
-2.9
|
bifidobacterium lactis bb12 (probiotics)
ππ½οΈ Dosages
|
π
|
-3
|
bifidobacterium longum (probiotics)
ππ½οΈ Dosages
|
π
|
-3.1
|
fibre-rich macrobiotic ma-pi 2 diet
|
π
|
-3.1
|
mediterranean diet
|
π
|
-3.1
|
selenium
ππ½οΈ Dosages
|
π
|
-3.2
|
resistant maltodextrin
ππ½οΈ Dosages
|
π
|
-3.3
|
nuts
|
π
|
-3.3
|
resveratrol (grape seed/polyphenols/red wine)
ππ½οΈ Dosages
|
π
|
-3.3
|
Alpha-Ketoglutarate
|
π
|
-3.5
|
vitamin d
ππ½οΈ Dosages
|
π
|
-3.6
|
lupin seeds (anaphylaxis risk, toxic if not prepared properly)
|
π
|
-3.7
|
kefir
|
π
|
-3.8
|
Curcumin
ππ½οΈ Dosages
|
π
|
-4
|
galacto-oligosaccharides (prebiotic)
ππ½οΈ Dosages
|
π
|
-4
|
oregano (origanum vulgare, oil) |
|
π
|
-4.1
|
Limosilactobacillus fermentum (probiotic)
ππ½οΈ Dosages
|
π
|
-4.4
|
fasting
|
π
|
-4.5
|
soy
ππ½οΈ Dosages
|
π
|
-4.5
|
vegetarians
|
π
|
-4.6
|
pectin
|
π
|
-4.6
|
Psyllium (Plantago Ovata Husk)
ππ½οΈ Dosages
|
π
|
-4.9
|
Moringa Oleifera
|
π
|
-4.9
|
pea (fiber, protein)
|
π
|
-4.9
|
cinnamon (oil. spice)
ππ½οΈ Dosages
|
π
|
-5.1
|
lactobacillus reuteri (probiotics)
ππ½οΈ Dosages
|
π
|
-5.2
|
lactobacillus paracasei (probiotics)
ππ½οΈ Dosages
|
π
|
-5.7
|
triphala
ππ½οΈ Dosages
|
π
|
-6.4
|
wheat
|
π
|
-6.4
|
lactobacillus acidophilus (probiotics)
ππ½οΈ Dosages
|
π
|
-6.5
|
berberine
ππ½οΈ Dosages
|
π
|
-6.7
|
apple
|
π
|
-6.7
|
clostridium butyricum (probiotics),Miya,Miyarisan
ππ½οΈ Dosages
|
π
|
-6.9
|
wheat bran
|
π
|
-6.9
|
Pulses
|
π
|
-7.2
|
xylan (prebiotic)
|
π
|
-8.2
|
lactobacillus rhamnosus gg (probiotics)
ππ½οΈ Dosages
|
π
|
-9.2
|
barley
ππ½οΈ Dosages
|
π
|
-9.9
|
arabinogalactan (prebiotic)
ππ½οΈ Dosages
|
π
|
-11.2
|
Human milk oligosaccharides (prebiotic, Holigos, Stachyose)
ππ½οΈ Dosages
|
π
|
-11.3
|
inulin (prebiotic)
ππ½οΈ Dosages
|
π
|
-14.7
|
lactobacillus plantarum (probiotics)
ππ½οΈ Dosages
|
π
|