Modelled supplements for ME/CFS without IBS

Conventional Beliefs

  1. Vitamin D: Some individuals with ME/CFS might have lower levels of vitamin D. Adequate levels of vitamin D are important for overall health, immune function, and bone health. Supplementation should be guided by healthcare professionals based on individual levels.

  2. Omega-3 Fatty Acids: Omega-3 fatty acids found in fish oil or certain plant-based sources may have anti-inflammatory properties that could potentially benefit some individuals with ME/CFS, although evidence specific to this condition is limited.

  3. Magnesium: Magnesium is involved in numerous bodily functions, including muscle and nerve function. Some people find that magnesium supplements can help with symptoms like muscle cramps, sleep disturbances, and fatigue, which are common in ME/CFS.

  4. B Vitamins: B vitamins play vital roles in energy production and nerve function. While research is ongoing, some individuals with ME/CFS might benefit from B-complex supplements. However, individual responses can vary, and excessive doses might not necessarily provide additional benefits.

  5. Coenzyme Q10 (CoQ10): CoQ10 is an antioxidant that plays a role in energy production within cells. Some individuals with ME/CFS report feeling improvements in energy levels with CoQ10 supplementation, although scientific evidence is limited.

For an explanation of how this is generated, see this post

All suggestions from this page should be reviewed by your medical professionals. These are based on modelling and not clinical studies.

Based on family and lower taxonomy ranks (genus,species,strains) reported in studies, the list is here

Net Impact Modifier Citations
5.3 vegetarians   πŸ“š
4.4 vitamin a   πŸ“πŸ½οΈ Dosages πŸ“š
3.1 Vitamin B9,folic acid   πŸ“πŸ½οΈ Dosages πŸ“š
2.7 Tributyrin   πŸ“š
2.6 rhubarb   πŸ“š
2.5 barley   πŸ“πŸ½οΈ Dosages πŸ“š
2.3 walnuts   πŸ“πŸ½οΈ Dosages πŸ“š
2.2 bifidobacterium pseudocatenulatum li09,bifidobacterium catenulatum li10 (probiotics)   πŸ“š
1.9 berberine   πŸ“πŸ½οΈ Dosages πŸ“š
1.9 amaranth   πŸ“š
1.8 Lithium   πŸ“š
1.8 bacillus coagulans (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
1.6 oligosaccharides (prebiotic)   πŸ“š
1.6 carob   πŸ“š
1.6 clostridium butyricum (probiotics),Miya,Miyarisan   πŸ“πŸ½οΈ Dosages πŸ“š
1.5 rare meat   πŸ“š
1.5 high-protein diet   πŸ“š
1.5 vsl#3 (probiotics)   πŸ“š
1.4 dairy   πŸ“š
1.4 Tudca   πŸ“š
1.3 candida albicans (prescription)   πŸ“š
1.3 dietary phytoestrogens (isoflavones)   πŸ“š
1.1 high red meat   πŸ“š
1.1 Ferric citrate   πŸ“š
1.1 Fruits (Cooked)   πŸ“š
1 fruit/legume fibre   πŸ“š
1 high carbohydrate diet   πŸ“š
1 lactobacillus reuteri (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
1 white button mushrooms   πŸ“š
0.9 ku ding cha tea   πŸ“š
0.9 hypocaloric hyperproteic diet   πŸ“š
0.9 fruit   πŸ“š
0.9 chrysanthemum morifolium   πŸ“š
0.9 grape polyphenols   πŸ“š
0.9 fenugreek   πŸ“š
0.9 fluorine   πŸ“š
0.9 Caffeine   πŸ“š
0.8 Hibiscus   πŸ“š
0.8 Bay Leaf   πŸ“š
0.8 Celery Seed   πŸ“š
0.8 Coffee   πŸ“š
0.8 Konjaku flour   πŸ“š
0.8 Tryptophan   πŸ“πŸ½οΈ Dosages πŸ“š
0.8 Lemongrass   πŸ“š
0.8 Piperine   πŸ“š
0.8 low protein diet   πŸ“š
0.8 Sijunzi decoction   πŸ“š
0.8 nuts   πŸ“š
0.8 chestnut tannins   πŸ“š
0.7 vitamin B7, biotin   πŸ“πŸ½οΈ Dosages πŸ“š
0.7 cruciferous vegetables (broccoli cabbage)   πŸ“š
0.7 laser trilobum l.,kefe cumin   πŸ“š
0.7 Mustard seed extract   πŸ“š
0.7 Papaya seed   πŸ“š
0.7 Parsley   πŸ“š
0.7 Sriracha sauce   πŸ“š
0.7 Taxifolin   πŸ“πŸ½οΈ Dosages πŸ“š
0.7 Cola (w/ aspartame)   πŸ“š
0.7 Lemon peel   πŸ“š
0.7 Horseradish   πŸ“š
0.7 Dandelion   πŸ“š
0.6 Kimchi   πŸ“š
0.6 alcoholic beverages   πŸ“š
0.6 rice   πŸ“š
0.6 General Biotics Equilibrium   πŸ“š
0.6 Prescript Assist (2018 Formula)   πŸ“š
0.6 cannabinoids   πŸ“š
0.6 acetic acid   πŸ“š
0.6 enriched butter diet   πŸ“š
0.6 naringenin(grapefruit) (Flavonoid)   πŸ“š
0.6 Hesperidin (polyphenol)   πŸ“πŸ½οΈ Dosages πŸ“š
0.5 slow digestible carbohydrates   πŸ“š
0.5 mannooligosaccharide (prebiotic)   πŸ“πŸ½οΈ Dosages πŸ“š
0.5 lupin kernel fiber (legume) (anaphylaxis risk, toxic if not prepared properly)   πŸ“š
0.5 Ginseng   πŸ“πŸ½οΈ Dosages πŸ“š
-0.5 Theanine   πŸ“š
-0.5 Bifidobacterium animalis   πŸ“š
-0.5 asparagus   πŸ“š
-0.5 Beet   πŸ“š
-0.5 L-carnitine   πŸ“š
-0.5 Cottage Cheese   πŸ“š
-0.5 Gluco-Oligosaccharides   πŸ“š
-0.5 Kiwifruit   πŸ“š
-0.5 linseed(flaxseed)   πŸ“πŸ½οΈ Dosages πŸ“š
-0.5 germinated barley food-stuff   πŸ“š
-0.5 grape fiber   πŸ“š
-0.5 maize   πŸ“š
-0.5 bean   πŸ“š
-0.5 yogurt   πŸ“š
-0.5 lactobacillus sakei (probiotics)   πŸ“š
-0.5 sesame   πŸ“š
-0.5 bacillus,lactobacillus,streptococcus,saccharomyces probiotic   πŸ“š
-0.5 Codonopsis pilosula   πŸ“š
-0.5 Bacillus clausii (Probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
-0.5 xylooligosaccharide (prebiotic)   πŸ“πŸ½οΈ Dosages πŸ“š
-0.5 Vitamin B-12   πŸ“πŸ½οΈ Dosages πŸ“š
-0.5 Vitamin B1,thiamine hydrochloride   πŸ“πŸ½οΈ Dosages πŸ“š
-0.5 buckwheat   πŸ“š
-0.5 moderate-protein moderate-carbohydrate   πŸ“š
-0.5 selenium   πŸ“πŸ½οΈ Dosages πŸ“š
-0.5 sesame cake/meal   πŸ“š
-0.5 persimmon tannin   πŸ“š
-0.5 plantain bananas   πŸ“š
-0.5 dietary fiber   πŸ“š
-0.5 doenjang (fermented bean paste)   πŸ“š
-0.5 bifidobacterium catenulatum,(probiotics)   πŸ“š
-0.5 glutamate   πŸ“š
-0.6 high sugar diet   πŸ“š
-0.6 lard   πŸ“š
-0.6 coptis chinensis, Chinese goldthread   πŸ“š
-0.6 garlic (allium sativum)   πŸ“πŸ½οΈ Dosages πŸ“š
-0.6 animal-based diet   πŸ“š
-0.6 bifidobacterium adolescentis,(probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
-0.6 melatonin supplement   πŸ“πŸ½οΈ Dosages πŸ“š
-0.6 diosmin,(polyphenol)   πŸ“πŸ½οΈ Dosages πŸ“š
-0.6 retinoic acid,(Vitamin A derivative)   πŸ“š
-0.6 Arbutin (polyphenol)   πŸ“πŸ½οΈ Dosages πŸ“š
-0.6 Vitamin B6,pyridoxine hydrochloride   πŸ“πŸ½οΈ Dosages πŸ“š
-0.6 helichrysum italicum,Immortelle   πŸ“š
-0.6 cinnamomum zeylanicum   πŸ“š
-0.6 cinnamomum tamala   πŸ“š
-0.6 lactobacillus delbrueckii bulgaricus,bifidobacterium bifidum,enterococcus faecium,candida pintolopesii,aspergillus oryzae (probiotics)   πŸ“š
-0.6 allium cepa   πŸ“š
-0.6 Opium poppy (Papaver somniferum)   πŸ“š
-0.6 Pork   πŸ“š
-0.6 Turmeric   πŸ“πŸ½οΈ Dosages πŸ“š
-0.6 noni   πŸ“πŸ½οΈ Dosages πŸ“š
-0.6 Kaempferol   πŸ“š
-0.6 camellia   πŸ“š
-0.7 PreforPro   πŸ“š
-0.7 low-fat diets   πŸ“š
-0.7 Goji (berry,juice)   πŸ“š
-0.7 propionate   πŸ“š
-0.7 mannitol   πŸ“š
-0.7 luteolin (flavonoid)   πŸ“πŸ½οΈ Dosages πŸ“š
-0.7 tannic acid   πŸ“š
-0.7 vegetable/fruit juice-based diets   πŸ“š
-0.7 laminaria hyperborea( tangle/cuvie - seaweed)   πŸ“š
-0.7 mastic gum (prebiotic)   πŸ“πŸ½οΈ Dosages πŸ“š
-0.7 peganum harmala (rue)   πŸ“š
-0.7 lauric acid(fatty acid in coconut oil,in palm kernel oil,)   πŸ“š
-0.7 magnesium   πŸ“πŸ½οΈ Dosages πŸ“š
-0.7 magnolia bark   πŸ“š
-0.7 l-taurine   πŸ“πŸ½οΈ Dosages πŸ“š
-0.7 high fiber diet   πŸ“š
-0.7 ginger   πŸ“š
-0.8 laminaria digitata,oarweed - seaweed   πŸ“š
-0.8 whole grain,bran   πŸ“š
-0.8 xylan (prebiotic)   πŸ“š
-0.8 micromeria fruticosa,White-leaved Savory   πŸ“š
-0.8 Aloe   πŸ“š
-0.8 Manuka Honey   πŸ“πŸ½οΈ Dosages πŸ“š
-0.8 Umcka   πŸ“š
-0.8 Pickle juice   πŸ“š
-0.8 Sauerkraut   πŸ“š
-0.8 Silver   πŸ“š
-0.8 emblica officinalis   πŸ“š
-0.9 Fish Sauce   πŸ“š
-0.9 Carrot (juice)   πŸ“š
-0.9 Fiber, total dietary   πŸ“š
-0.9 wormwood(artemisia)   πŸ“š
-0.9 annatto   πŸ“š
-0.9 high amylose cornstarch   πŸ“š
-0.9 sorghum   πŸ“š
-0.9 oolong tea polyphenols   πŸ“š
-0.9 oolong teas   πŸ“š
-0.9 olea europaea,olive leaf   πŸ“πŸ½οΈ Dosages πŸ“š
-0.9 palm kernel meal   πŸ“š
-0.9 Perilla frutescens(shiso)   πŸ“πŸ½οΈ Dosages πŸ“š
-0.9 gluten-free diet   πŸ“š
-0.9 bifidobacterium animalis lactis (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
-0.9 withania somnifera,ashwagandha   πŸ“πŸ½οΈ Dosages πŸ“š
-0.9 carboxymethyl cellulose (prebiotic)   πŸ“š
-1 coriander oil   πŸ“š
-1 jerusalem artichoke (prebiotic)   πŸ“πŸ½οΈ Dosages πŸ“š
-1 polyphenols   πŸ“πŸ½οΈ Dosages πŸ“š
-1 red wine   πŸ“πŸ½οΈ Dosages πŸ“š
-1 Spearmint(mentha spicata)   πŸ“š
-1.1 lemon   πŸ“š
-1.1 bacillus laterosporus (probiotic)   πŸ“š
-1.1 Psyllium (Plantago Ovata Husk)   πŸ“πŸ½οΈ Dosages πŸ“š
-1.1 Bromelain   πŸ“πŸ½οΈ Dosages πŸ“š
-1.1 Ursolic acid   πŸ“š
-1.1 rice bran   πŸ“š
-1.1 green-lipped mussel   πŸ“š
-1.1 kefir   πŸ“š
-1.1 corn   πŸ“š
-1.1 quercetin   πŸ“πŸ½οΈ Dosages πŸ“š
-1.1 nephelium longan,lychee fruit   πŸ“š
-1.1 fraxinus angustifolia,narrow-leafed ash   πŸ“š
-1.2 iron   πŸ“πŸ½οΈ Dosages πŸ“š
-1.2 anise   πŸ“πŸ½οΈ Dosages πŸ“š
-1.2 partially hydrolysed guar gum,fructo-oligosaccharides (prebiotic)   πŸ“š
-1.2 chondrus crispus,red sea weed   πŸ“š
-1.2 sarcodiotheca gaudichaudii (red sea weed)   πŸ“š
-1.2 blueberry   πŸ“š
-1.2 brassica juncea   πŸ“š
-1.2 Mangosteen   πŸ“š
-1.2 potatoes   πŸ“š
-1.3 Cranberry   πŸ“š
-1.3 pectin   πŸ“š
-1.3 xylaria hypoxylon (fungi)   πŸ“š
-1.3 fibre-rich macrobiotic ma-pi 2 diet   πŸ“š
-1.3 Guaiacol (polyphenol)   πŸ“š
-1.4 satureia montana(Winter savory)   πŸ“š
-1.4 paenibacillus polymyxa (prescript assist) (probiotics)   πŸ“š
-1.4 neem   πŸ“πŸ½οΈ Dosages πŸ“š
-1.4 mutaflor escherichia coli nissle 1917 (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
-1.4 tomato powder   πŸ“š
-1.4 high resistant starch   πŸ“š
-1.4 abies alba mill, silver fir   πŸ“š
-1.4 bacillus subtilis natto (probiotics)   πŸ“š
-1.4 carum carvi, Caraway   πŸ“š
-1.4 whole-grain wheat   πŸ“š
-1.4 bifidobacterium longum,lactobacillus helveticus (probiotics)   πŸ“š
-1.4 lactobacillus paracasei,lactobacillus acidophilus,bifidobacterium animalis (probiotics)   πŸ“š
-1.4 rye   πŸ“š
-1.4 bifidobacterium (probiotics)   πŸ“š
-1.4 Conjugated Linoleic Acid   πŸ“š
-1.4 hou-po-da-huang-tang   πŸ“š
-1.4 Pistachio   πŸ“š
-1.5 plantago asiatica l.   πŸ“š
-1.5 chitooligosaccharides (prebiotic)   πŸ“πŸ½οΈ Dosages πŸ“š
-1.5 basil   πŸ“š
-1.5 lactobacillus kefiri (NOT KEFIR)   πŸ“š
-1.5 triphala   πŸ“πŸ½οΈ Dosages πŸ“š
-1.5 vitamin d   πŸ“πŸ½οΈ Dosages πŸ“š
-1.5 tea   πŸ“š
-1.6 sesuvium portulacastrum herb   πŸ“š
-1.6 fat   πŸ“š
-1.6 Alpha-Ketoglutarate   πŸ“š
-1.7 red alga Laurencia tristicha   πŸ“š
-1.7 pea (fiber, protein)   πŸ“š
-1.7 bifidobacterium lactis bb12 (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
-1.7 Burdock Root   πŸ“š
-1.7 pediococcus acidilactic (probiotic)   πŸ“š
-1.7 purple sweet potatoes   πŸ“š
-1.7 marjoram   πŸ“š
-1.7 ketogenic diet   πŸ“š
-1.7 grape seed extract   πŸ“πŸ½οΈ Dosages πŸ“š
-1.8 glycyrrhizic acid (licorice)   πŸ“πŸ½οΈ Dosages πŸ“š
-1.8 oligofructose-enriched inulin (prebiotic)   πŸ“š
-1.8 blackcurrant   πŸ“š
-1.8 peppermint (spice, oil)   πŸ“š
-1.8 Sumac(Rhus coriaria)   πŸ“š
-1.8 schinus molle (herb)   πŸ“š
-1.8 tabebuia impetiginosa (taheebo) bark   πŸ“š
-1.8 brown algae   πŸ“š
-1.9 resistant maltodextrin   πŸ“πŸ½οΈ Dosages πŸ“š
-1.9 omega-3 fatty acids   πŸ“πŸ½οΈ Dosages πŸ“š
-1.9 trametes versicolor(Turkey tail mushroom)   πŸ“š
-1.9 wheat   πŸ“š
-1.9 almonds/ almond skins   πŸ“πŸ½οΈ Dosages πŸ“š
-2 bifidobacterium longum (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
-2 lactobacillus rhamnosus (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
-2.1 lactobacillus brevis (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
-2.2 broccoli   πŸ“š
-2.2 oats   πŸ“š
-2.3 syzygium aromaticum (clove)   πŸ“š
-2.3 bacillus licheniformis,(probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
-2.3 Moringa Oleifera   πŸ“š
-2.4 cinnamon (oil. spice)   πŸ“πŸ½οΈ Dosages πŸ“š
-2.4 trachyspermum ammi, Ajwain   πŸ“š
-2.4 Umeboshi (Japanese Apricot or Prunus mume )   πŸ“š
-2.5 lactobacillus acidophilus (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
-2.5 lactobacillus casei shirota (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
-2.6 green tea   πŸ“š
-2.6 gum arabic (prebiotic)   πŸ“πŸ½οΈ Dosages πŸ“š
-2.6 banana   πŸ“š
-2.6 bifidobacterium bifidum (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
-2.7 lactobacillus fermentum (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
-2.7 zinc   πŸ“πŸ½οΈ Dosages πŸ“š
-2.9 thyme (thymol, thyme oil)   πŸ“š
-2.9 lactobacillus plantarum,xylooligosaccharides,(prebiotic) (probiotics)   πŸ“š
-2.9 mediterranean diet   πŸ“š
-2.9 fasting   πŸ“š
-2.9 cranberry bean flour   πŸ“š
-2.9 enterococcus faecium (probiotic)   πŸ“πŸ½οΈ Dosages πŸ“š
-3 partially hydrolyzed guar gum   πŸ“πŸ½οΈ Dosages πŸ“š
-3.1 Glucomannan   πŸ“πŸ½οΈ Dosages πŸ“š
-3.1 resveratrol (grape seed/polyphenols/red wine)   πŸ“πŸ½οΈ Dosages πŸ“š
-3.4 resistant starch   πŸ“š
-3.5 Curcumin   πŸ“πŸ½οΈ Dosages πŸ“š
-3.8 whey   πŸ“πŸ½οΈ Dosages πŸ“š
-3.9 Cacao   πŸ“πŸ½οΈ Dosages πŸ“š
-4.2 lactobacillus plantarum (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
-4.5 arabinogalactan (prebiotic)   πŸ“πŸ½οΈ Dosages πŸ“š
-5.3 bacillus subtilis (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
-5.4 inulin (prebiotic)   πŸ“πŸ½οΈ Dosages πŸ“š
-5.6 galacto-oligosaccharides (prebiotic)   πŸ“πŸ½οΈ Dosages πŸ“š
-5.6 wheat bran   πŸ“š
-5.8 apple   πŸ“š
-6.8 soy   πŸ“πŸ½οΈ Dosages πŸ“š
-7.4 rosmarinus officinalis,rosemary   πŸ“š
-7.9 lactobacillus paracasei (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
-8.2 lactobacillus casei (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
-8.4 fructo-oligosaccharides (prebiotic)   πŸ“πŸ½οΈ Dosages πŸ“š
-15.8 Human milk oligosaccharides (prebiotic, Holigos, Stachyose)   πŸ“πŸ½οΈ Dosages πŸ“š

All suggestions are computed solely on their predicted microbiome impact. Safety, side-effects etc must be evaluated by your medical professionals before starting. Some items suggests have significant risk of adverse consequences for some people.

Special thanks to David F Morrison and Geert Van Houcke for doing Quality Assurance. Special thanks to Oliver Luk, B.Sc. (Biology) from BiomeSight for spot checking the coding of data from the US National Library of Medicine

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