Modelled supplements for Neuropathy (all types)

Conventional Beliefs

  1. Alpha-Lipoic Acid: Alpha-lipoic acid, an antioxidant, is sometimes used for individuals with diabetic neuropathy. It may have neuroprotective effects and could potentially help reduce symptoms like pain or tingling. However, evidence regarding its effectiveness is mixed, and it may not work for everyone.

  2. Vitamin B Complex: Certain B vitamins, particularly B1 (thiamine), B6 (pyridoxine), and B12 (cobalamin), are essential for nerve health and function. Some individuals with neuropathy, especially those with deficiencies, might benefit from B vitamin supplementation. However, excessive doses should be avoided as they might have adverse effects.

  3. Omega-3 Fatty Acids: Omega-3 fatty acids found in fish oil or certain plant-based sources may have anti-inflammatory properties that could potentially provide general health support. Some studies suggest they might help reduce inflammation and nerve damage, but their specific role in neuropathy requires further research.

  4. Vitamin D: Adequate levels of vitamin D are important for overall health. Some research suggests a potential association between low vitamin D levels and neuropathy. However, its direct impact on neuropathy is not fully understood.

  5. Probiotics: While not directly related to neuropathy, maintaining a healthy gut microbiome might indirectly support overall health. Some studies suggest that probiotics might have a role in modulating inflammation and immune function, which could potentially impact certain neuropathic conditions.

For an explanation of how this is generated, see this post

All suggestions from this page should be reviewed by your medical professionals. These are based on modelling and not clinical studies.

Based on family and lower taxonomy ranks (genus,species,strains) reported in studies, the list is here

Net Impact Modifier Citations
35.2 inulin (prebiotic)   πŸ“πŸ½οΈ Dosages πŸ“š
23.2 lactobacillus plantarum (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
22.7 bacillus subtilis (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
16.1 lactobacillus reuteri (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
14.2 Olive Oil   πŸ“š
13.4 fructo-oligosaccharides (prebiotic)   πŸ“πŸ½οΈ Dosages πŸ“š
13.3 barley   πŸ“πŸ½οΈ Dosages πŸ“š
12.6 arabinogalactan (prebiotic)   πŸ“πŸ½οΈ Dosages πŸ“š
10.5 quebracho   πŸ“š
9.3 vitamin d   πŸ“πŸ½οΈ Dosages πŸ“š
9.1 lactobacillus rhamnosus gg (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
9 Burdock Root   πŸ“š
8.7 wheat   πŸ“š
8.7 berberine   πŸ“πŸ½οΈ Dosages πŸ“š
8.7 fasting   πŸ“š
8.6 clostridium butyricum (probiotics),Miya,Miyarisan   πŸ“πŸ½οΈ Dosages πŸ“š
7.9 enterococcus faecium (probiotic)   πŸ“πŸ½οΈ Dosages πŸ“š
7.7 black raspberries   πŸ“πŸ½οΈ Dosages πŸ“š
7.6 Ursolic acid   πŸ“š
7.4 Lactobacillus Johnsonii (probiotic)   πŸ“πŸ½οΈ Dosages πŸ“š
7.4 Limosilactobacillus fermentum (probiotic)   πŸ“πŸ½οΈ Dosages πŸ“š
7.3 wheat bran   πŸ“š
7.3 chestnut tannins   πŸ“š
7 Moringa Oleifera   πŸ“š
6.5 brown rice   πŸ“š
6.1 soy   πŸ“πŸ½οΈ Dosages πŸ“š
5.9 barley,oat   πŸ“š
5.8 pediococcus acidilactic (probiotic)   πŸ“š
5.6 bifidobacterium longum (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
5.5 high-fat diets   πŸ“š
5.4 garlic (allium sativum)   πŸ“πŸ½οΈ Dosages πŸ“š
5.4 Tudca   πŸ“πŸ½οΈ Dosages πŸ“š
5.3 glycine   πŸ“πŸ½οΈ Dosages πŸ“š
5.1 fruit/legume fibre   πŸ“š
5 bifidobacterium bifidum (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
5 oligosaccharides (prebiotic)   πŸ“š
5 ketogenic diet   πŸ“š
4.9 dairy   πŸ“š
4.9 pea (fiber, protein)   πŸ“š
4.9 Sodium alginate   πŸ“πŸ½οΈ Dosages πŸ“š
4.8 Dangshen   πŸ“š
4.7 chrysanthemum morifolium   πŸ“š
4.7 quercetin   πŸ“πŸ½οΈ Dosages πŸ“š
4.7 resveratrol (grape seed/polyphenols/red wine)   πŸ“πŸ½οΈ Dosages πŸ“š
4.6 lactobacillus acidophilus (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
4.6 omega-3 fatty acids   πŸ“πŸ½οΈ Dosages πŸ“š
4.6 polygonatum kingianum(Orange Flower Solomon's Seal.)   πŸ“š
4.6 apple   πŸ“š
4.5 Conjugated Linoleic Acid   πŸ“š
4.4 Human milk oligosaccharides (prebiotic, Holigos, Stachyose)   πŸ“πŸ½οΈ Dosages πŸ“š
4.4 lactobacillus casei (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
4.4 rhubarb   πŸ“š
4.3 sodium butyrate   πŸ“š
4.3 Alpha-Ketoglutarate   πŸ“š
4.2 Whole Cow milk   πŸ“š
4.2 pomegranate   πŸ“πŸ½οΈ Dosages πŸ“š
4.2 palm kernel meal   πŸ“š
4.2 acetic acid   πŸ“š
4.1 bacillus licheniformis,(probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
4.1 lactobacillus paracasei (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
4.1 walnuts   πŸ“πŸ½οΈ Dosages πŸ“š
4.1 rosmarinus officinalis,rosemary   πŸ“š
4 fish oil   πŸ“πŸ½οΈ Dosages πŸ“š
4 Apigenin   πŸ“š
4 Fisetin   πŸ“πŸ½οΈ Dosages πŸ“š
3.8 banana   πŸ“š
3.8 Ginseng   πŸ“πŸ½οΈ Dosages πŸ“š
3.8 blueberry   πŸ“š
3.8 Vitamin E   πŸ“πŸ½οΈ Dosages πŸ“š
3.7 Nicotine, Nicotine Patch   πŸ“š
3.7 whole grain,bran   πŸ“š
3.7 Shen Ling Bai Zhu San   πŸ“š
3.6 Pulses   πŸ“š
3.5 gum arabic (prebiotic)   πŸ“πŸ½οΈ Dosages πŸ“š
3.5 vitamin a   πŸ“πŸ½οΈ Dosages πŸ“š
3.3 xylooligosaccharide (prebiotic)   πŸ“πŸ½οΈ Dosages πŸ“š
3.3 bifidobacterium lactis bb12 (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
3.3 bioflorin,enterococcus faecium sf 68,(probiotics)   πŸ“š
3.3 lactobacillus plantarum,xylooligosaccharides,(prebiotic) (probiotics)   πŸ“š
3.2 lactobacillus rhamnosus (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
3.2 safflower oil   πŸ“š
3.2 bifidobacterium animalis lactis (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
3.2 Vitamin B-12   πŸ“πŸ½οΈ Dosages πŸ“š
3.2 pectin   πŸ“š
3.2 Vitamin B   πŸ“š
3.2 Rhubarb Peony Decoction   πŸ“š
3.1 Glucomannan   πŸ“πŸ½οΈ Dosages πŸ“š
3.1 plantago asiatica l.   πŸ“š
3.1 choline   πŸ“πŸ½οΈ Dosages πŸ“š
3.1 high fiber diet   πŸ“š
3.1 saccharomyces boulardii (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
3.1 Guaiacol (polyphenol)   πŸ“š
3.1 lupin seeds (anaphylaxis risk, toxic if not prepared properly)   πŸ“š
3 oregano (origanum vulgare, oil) |   πŸ“š
3 vsl#3 (probiotics)   πŸ“š
3 bifidobacterium adolescentis,(probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
3 zinc   πŸ“πŸ½οΈ Dosages πŸ“š
3 noni   πŸ“πŸ½οΈ Dosages πŸ“š
2.9 bacillus coagulans (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
2.9 fruit   πŸ“š
2.8 grapes   πŸ“š
2.8 Astragalus   πŸ“š
2.7 Kiwifruit   πŸ“š
2.7 spirulina(cyanobacteria)   πŸ“š
2.7 galacto-oligosaccharides (prebiotic)   πŸ“πŸ½οΈ Dosages πŸ“š
2.7 high sugar diet   πŸ“š
2.7 lauric acid(fatty acid in coconut oil,in palm kernel oil,)   πŸ“š
2.7 Bromelain   πŸ“πŸ½οΈ Dosages πŸ“š
2.7 Pistachio   πŸ“š
2.6 vegetable   πŸ“š
2.6 resistant maltodextrin   πŸ“πŸ½οΈ Dosages πŸ“š
2.6 grape seed extract   πŸ“πŸ½οΈ Dosages πŸ“š
2.6 almonds/ almond skins   πŸ“πŸ½οΈ Dosages πŸ“š
2.6 capsaicin (hot pepper)   πŸ“š
2.6 xylan (prebiotic)   πŸ“š
2.5 linseed(flaxseed)   πŸ“πŸ½οΈ Dosages πŸ“š
2.5 Coenzyme Q10   πŸ“πŸ½οΈ Dosages πŸ“š
2.4 Baicalin   πŸ“š
2.4 Exercise   πŸ“š
2.4 Caffeine   πŸ“š
2.4 Vitamin C (ascorbic acid)   πŸ“πŸ½οΈ Dosages πŸ“š
2.4 bifidobacterium pseudocatenulatum,(probiotics)   πŸ“š
2.4 aspergillus oryzae   πŸ“š
2.4 foeniculum vulgare,fennel   πŸ“š
2.3 ku ding cha tea   πŸ“š
2.3 magnesium   πŸ“πŸ½οΈ Dosages πŸ“š
2.3 Ferric citrate   πŸ“š
2.3 low protein diet   πŸ“š
2.3 Bofutsushosan   πŸ“š
2.3 Tryptophan   πŸ“πŸ½οΈ Dosages πŸ“š
2.2 Oyster Mushroom   πŸ“š
2.2 Boron (Organic Source)   πŸ“š
2.2 bacillus,lactobacillus,streptococcus,saccharomyces probiotic   πŸ“š
2.2 Pork   πŸ“š
2.2 whole-grain wheat   πŸ“š
2.2 kefir   πŸ“š
2.2 l-proline   πŸ“š
2.2 jerusalem artichoke (prebiotic)   πŸ“πŸ½οΈ Dosages πŸ“š
2.1 grape polyphenols   πŸ“š
2.1 buckwheat   πŸ“š
2.1 luteolin (flavonoid)   πŸ“πŸ½οΈ Dosages πŸ“š
2.1 amaranth   πŸ“š
2 western diet   πŸ“š
2 animal-based diet   πŸ“š
2 bacillus (probiotics)   πŸ“š
2 bifidobacterium catenulatum,(probiotics)   πŸ“š
2 l-sorbose   πŸ“š
2 red wine   πŸ“πŸ½οΈ Dosages πŸ“š
2 sunflower oil   πŸ“š
2 whey   πŸ“πŸ½οΈ Dosages πŸ“š
2 Kaempferol   πŸ“š
1.9 selenium   πŸ“πŸ½οΈ Dosages πŸ“š
1.9 Akkermansia muciniphila (probiotic)   πŸ“πŸ½οΈ Dosages πŸ“š
1.9 rye   πŸ“š
1.8 green tea   πŸ“š
1.8 fibre-rich macrobiotic ma-pi 2 diet   πŸ“š
1.7 hypocaloric hyperproteic diet   πŸ“š
1.7 mulberry fruit polysaccharide   πŸ“š
1.7 cruciferous vegetables (broccoli cabbage)   πŸ“š
1.7 grape fiber   πŸ“š
1.6 dietary phytoestrogens (isoflavones)   πŸ“š
1.6 germinated barley food-stuff   πŸ“š
1.6 iron   πŸ“πŸ½οΈ Dosages πŸ“š
1.6 cinnamon (oil. spice)   πŸ“πŸ½οΈ Dosages πŸ“š
1.6 Goat milk   πŸ“š
1.6 punicic acid   πŸ“š
1.6 Mangosteen   πŸ“š
1.6 asparagus   πŸ“š
1.5 Lactobacillus pentosus   πŸ“š
1.5 high resistant starch   πŸ“š
1.5 lactobacillus brevis (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
1.5 green-lipped mussel   πŸ“š
1.5 cellulose (prebiotic)   πŸ“š
1.5 Slippery Elm   πŸ“š
1.5 Curcumin   πŸ“πŸ½οΈ Dosages πŸ“š
1.5 Codonopsis pilosula   πŸ“š
1.4 Bacillus clausii (Probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
1.4 broccoli   πŸ“š
1.4 emblica officinalis   πŸ“š
1.3 Pumpkin   πŸ“š
1.3 doenjang (fermented bean paste)   πŸ“š
1.3 high red meat   πŸ“š
1.3 Artemisinin   πŸ“š
1.2 salt (sodium chloride)   πŸ“š
1.2 starch-fed   πŸ“š
1.2 yogurt   πŸ“š
1.2 hou-po-da-huang-tang   πŸ“š
1.2 dietary fiber   πŸ“š
1.2 vitamin B3,niacin   πŸ“πŸ½οΈ Dosages πŸ“š
1.2 persimmon tannin   πŸ“š
1.2 Rutin   πŸ“πŸ½οΈ Dosages πŸ“š
1.2 Papain   πŸ“š
1.1 Pancreatin   πŸ“š
1.1 Lithium   πŸ“š
1.1 Rhodiola rosea (Rosavin)   πŸ“πŸ½οΈ Dosages πŸ“š
1.1 quinoa   πŸ“š
1.1 Glucosamine   πŸ“š
1.1 sesame cake/meal   πŸ“š
1.1 schisandra chinensis(magnolia berry or five-flavor-fruit)   πŸ“š
1.1 whole-grain barley   πŸ“πŸ½οΈ Dosages πŸ“š
1.1 l-arginine   πŸ“πŸ½οΈ Dosages πŸ“š
1.1 chicory (prebiotic)   πŸ“πŸ½οΈ Dosages πŸ“š
1.1 potatoes   πŸ“š
1.1 strawberry   πŸ“š
1.1 Gluco-Oligosaccharides   πŸ“š
1.1 Onion   πŸ“š
1.1 Peanut   πŸ“š
1.1 Pineapple   πŸ“š
1.1 Sauerkraut   πŸ“š
1.1 mannitol   πŸ“š
1.1 sesame   πŸ“š
1.1 corn   πŸ“š
1 genistein   πŸ“š
1 carob   πŸ“š
1 beef   πŸ“š
1 fat   πŸ“š
1 Fruits (Cooked)   πŸ“š
1 Xanthan gum   πŸ“š
1 carrageenan   πŸ“š
0.9 fucoidan   πŸ“πŸ½οΈ Dosages πŸ“š
0.9 glutamate   πŸ“š
0.9 bacillus subtilis natto (probiotics)   πŸ“š
0.9 white button mushrooms   πŸ“š
0.9 low carbohydrate diet   πŸ“š
0.9 Turmeric   πŸ“πŸ½οΈ Dosages πŸ“š
0.9 PreforPro   πŸ“š
0.9 Soymilk   πŸ“š
0.9 bifidobacterium (probiotics)   πŸ“š
0.8 nigella sativa seed (black cumin)   πŸ“πŸ½οΈ Dosages πŸ“š
0.8 purple sweet potatoes   πŸ“š
0.8 eugenol (from clove oil, nutmeg, cinnamon, basil,bay leaf.)   πŸ“š
0.8 oats   πŸ“š
0.8 high beef diet   πŸ“š
0.8 Rosmarinic acid   πŸ“š
0.8 Bell Pepper   πŸ“š
0.7 Dextrin   πŸ“πŸ½οΈ Dosages πŸ“š
0.7 gluten   πŸ“š
0.7 bifidobacterium infantis,(probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
0.7 nuts   πŸ“š
0.7 navy bean   πŸ“š
0.7 partially hydrolysed guar gum (prebiotic)   πŸ“š
0.6 chondrus crispus,red sea weed   πŸ“š
0.6 sarcodiotheca gaudichaudii (red sea weed)   πŸ“š
0.6 blackcurrant   πŸ“š
0.6 Cranberry   πŸ“š
0.6 lard   πŸ“š
0.6 slow digestible carbohydrates   πŸ“š
0.6 trametes versicolor(Turkey tail mushroom)   πŸ“š
0.6 vitamin b2,Riboflavin   πŸ“πŸ½οΈ Dosages πŸ“š
0.6 Pterostilbene   πŸ“š
0.6 chlorine   πŸ“š
0.5 Cistus Incanus   πŸ“š
0.5 Fucose   πŸ“š
0.5 Amylopectin   πŸ“š
0.5 nobiletin   πŸ“š
0.5 tulsi   πŸ“πŸ½οΈ Dosages πŸ“š
0.5 rosa canina   πŸ“š
0.5 polyphenols   πŸ“πŸ½οΈ Dosages πŸ“š
0.5 mutaflor escherichia coli nissle 1917 (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
0.5 lavender   πŸ“š
0.5 lemongrass oil   πŸ“š
0.5 laminaria digitata,oarweed - seaweed   πŸ“š
0.5 hypericin, St. John's Wort   πŸ“š
0.5 Pediococcus pentosaceus   πŸ“š
0.5 lactobacillus helveticus   πŸ“š
0.5 chicken   πŸ“š
0.5 papaya   πŸ“š
0.5 milk thistle(silybum marianum)   πŸ“πŸ½οΈ Dosages πŸ“š
0.5 leea indica,bandicoot berry   πŸ“š
0.5 galla rhois   πŸ“š
0.5 red chiles (Capsicum)   πŸ“š
0.5 rosehip tea   πŸ“š
0.5 pomegranate blossom tea   πŸ“š
0.5 laser trilobum l.,kefe cumin   πŸ“š
0.5 high amylose cornstarch   πŸ“š
0.5 vitex negundo (herb)   πŸ“š
0.5 fenugreek   πŸ“š
-0.5 Hesperidin (polyphenol)   πŸ“πŸ½οΈ Dosages πŸ“š
-0.5 ethanol   πŸ“š
-0.6 Vitamin B1,thiamine hydrochloride   πŸ“πŸ½οΈ Dosages πŸ“š
-0.6 quercetin,resveratrol   πŸ“š
-0.6 colinfant e.coli probiotics   πŸ“š
-0.7 oligofructose-enriched inulin (prebiotic)   πŸ“š
-0.7 coriander oil   πŸ“š
-0.7 candida albicans (prescription)   πŸ“š
-0.7 bifidobacterium longum bb536 (probiotics)   πŸ“š
-0.7 lactobacillus salivarius (probiotics)   πŸ“πŸ½οΈ Dosages πŸ“š
-0.7 triphala   πŸ“πŸ½οΈ Dosages πŸ“š
-0.8 magnolia bark   πŸ“š
-0.8 peganum harmala (rue)   πŸ“š
-0.8 withania somnifera,ashwagandha   πŸ“πŸ½οΈ Dosages πŸ“š
-0.8 rare meat   πŸ“š
-0.8 lupin kernel fiber (legume) (anaphylaxis risk, toxic if not prepared properly)   πŸ“š
-0.8 lemon   πŸ“š
-0.8 Sodas   πŸ“š
-0.8 colostrum   πŸ“š
-0.9 L-carnitine   πŸ“š
-0.9 cannabinoids   πŸ“š
-0.9 low-fat diets   πŸ“š
-0.9 chaga (mushroom)   πŸ“š
-1 fraxinus angustifolia,narrow-leafed ash   πŸ“š
-1 high-fat sucrose   πŸ“š
-1 diosmin,(polyphenol)   πŸ“πŸ½οΈ Dosages πŸ“š
-1 Manjistha (Rubia cordifolia)   πŸ“š
-1.1 Far infrared Sauna   πŸ“š
-1.1 mastic gum (prebiotic)   πŸ“πŸ½οΈ Dosages πŸ“š
-1.2 bifidobacterium pseudocatenulatum li09,bifidobacterium catenulatum li10 (probiotics)   πŸ“š
-1.2 galla chinensis (herb)   πŸ“š
-1.2 brassica juncea   πŸ“š
-1.2 ginko   πŸ“πŸ½οΈ Dosages πŸ“š
-1.2 Grapefruit seed extract   πŸ“š
-1.3 Apple skin   πŸ“š
-1.3 lactobacillus delbrueckii bulgaricus,bifidobacterium bifidum,enterococcus faecium,candida pintolopesii,aspergillus oryzae (probiotics)   πŸ“š
-1.3 propionate   πŸ“š
-1.3 symbioflor 2 e.coli probiotics   πŸ“š
-1.5 fluorine   πŸ“š
-1.6 oolong tea polyphenols   πŸ“š
-1.6 lactobacillus rhamnosus gg,lactobacillus,rhamnosus,propionibacterium freudenreichii,bifidobacterium breve (probiotics)   πŸ“š
-1.6 lactobacillus sakei (probiotics)   πŸ“š
-1.6 high-protein diet   πŸ“š
-1.7 l-glutamine   πŸ“πŸ½οΈ Dosages πŸ“š
-1.7 low-fat high-complex carbohydrate diet   πŸ“š
-1.7 l-taurine   πŸ“πŸ½οΈ Dosages πŸ“š
-1.7 annatto   πŸ“š
-1.7 bacillus laterosporus (probiotic)   πŸ“š
-1.7 camelina seed   πŸ“š
-1.8 whole grain diet   πŸ“š
-1.8 glycyrrhizic acid (licorice)   πŸ“πŸ½οΈ Dosages πŸ“š
-1.9 GABA   πŸ“πŸ½οΈ Dosages πŸ“š
-2 Sumac(Rhus coriaria)   πŸ“š
-2 trachyspermum ammi, Ajwain   πŸ“š
-2 red alga Laurencia tristicha   πŸ“š
-2.1 sorghum   πŸ“š
-2.1 neem   πŸ“πŸ½οΈ Dosages πŸ“š
-2.2 Vitamin B9,folic acid   πŸ“πŸ½οΈ Dosages πŸ“š
-2.3 bacillus amyloliquefaciens (probiotic)   πŸ“πŸ½οΈ Dosages πŸ“š
-2.3 Umeboshi (Japanese Apricot or Prunus mume )   πŸ“š
-2.4 tea   πŸ“š
-2.5 Baking Soda, Sodium Bicarbonate   πŸ“š
-2.7 oolong teas   πŸ“š
-3.2 carboxymethyl cellulose (prebiotic)   πŸ“š
-3.9 vegetable/fruit juice-based diets   πŸ“š
-3.9 Tributyrin   πŸ“š
-4.6 alcoholic beverages   πŸ“š
-8.1 gluten-free diet   πŸ“š

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