Details about Actinomyces: NCBI 1654, high G+C gram-positive

  1. Normal Flora:

    • Many Actinomyces species are part of the normal microbial flora in the oral cavity, gastrointestinal tract, and genital tract of humans. In these settings, they contribute to the balance of the microbiota and may have beneficial roles.
  2. Pathogenic Potential:

    • While Actinomyces species are generally commensal, some can become opportunistic pathogens. Actinomyces species can cause infections, most notably actinomycosis. Actinomycosis is a chronic suppurative and granulomatous infection that can occur in various body sites, including the cervicofacial area, thorax, abdomen, and pelvis.
  3. Actinomycosis:

    • Actinomycosis is characterized by the formation of abscesses, draining sinuses, and the presence of characteristic sulfur granules in the affected tissues. The condition often arises due to disruption of mucosal barriers, allowing Actinomyces to invade deeper tissues. Cervicofacial actinomycosis is one of the more common forms.
  4. Dental Health:

    • Actinomyces species are commonly found in dental plaque and can be involved in dental caries and periodontal diseases. Maintaining good oral hygiene is important to prevent the overgrowth of potentially pathogenic bacteria.
  5. Pelvic Inflammatory Disease (PID):

    • In the genital tract, Actinomyces species have been associated with pelvic inflammatory disease (PID), particularly in women with intrauterine devices (IUDs). This is considered a rare complication.
  6. Endocarditis:

    • Actinomyces species have been implicated in infective endocarditis, particularly in individuals with pre-existing heart valve abnormalities.
  7. Treatment:

    • Actinomycosis is typically treated with prolonged courses of antibiotics, often involving penicillin or other beta-lactam antibiotics. Surgical drainage and debridement may be necessary in severe cases.

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More Information
Statistics 6729 Interactions with Other Bacteria NCBI Data Punk End Products Produced

Lab Reporting

Different labs use different software to read the sample. See this post for more details.
One lab may say you have none, another may say you have a lot! - This may be solely due to the software they are using to estimate.
We deem lab specific values using values from the KM method for each specific lab to be the most reliable.

Desired Levels Suggestions for Actinomyces

Using Kaltoft-Moldrup Heuristic Using uploaded data for Actinomyces

Lab Low and High are calculated using the formula that most labs use: Mean - 2 Standard Deviation to Mean + 2 Standard Deviation

These are values that are computed from lab specific samples (Patent Pending)
LabKM LowKM Percentile LowKM HighKM Percentile HighLab LowLab HighMeanStandard Deviation
All 0.001 3.4 %ile 0.124 97.4 %ile 0 0.26 0.025 0.119
BiomeSight 0.001 2.2 %ile 0.09 97.4 %ile 0 0.151 0.017 0.068
Ombre/Thryve 0.002 7.1 %ile 0.079 96.6 %ile 0 0.126 0.018 0.055
uBiome 0.002 0 %ile 0.177 95.9 %ile 0 0.536 0.059 0.243
Lab Suggestions for Actinomyces
Actinomyces (NCBI 1654) per million
Low Boundary High Boundary Low Boundary %age High Boundary %age Lab Samples
0 10000 0 1 Metagenomics
Statistic by Lab Source for Actinomyces
These desired values are reported from the lab reports
Lab Frequency Seen Average Standard Deviation Sample Count Lab Samples
bugspeak 100 %   0.016 %  % 1.0 1
BiomeSightRdp 35.556 %   0.012 %  0.02 % 16.0 45
CosmosId 78.947 %   0.073 %  0.157 % 30.0 38
AmericanGut 27.778 %   0.017 %  0.018 % 5.0 18
es-xenogene 14.286 %   0.019 %  0.012 % 5.0 35
SequentiaBiotech 27.778 %   0.079 %  0.062 % 10.0 36
Thorne 100 %   0.012 %  0.01 % 55.0 55
Tiny 100 %   0.008 %  % 1.0 1
uBiome 73.14 %   0.058 %  0.243 % 580.0 793
BiomeSight 72.727 %   0.017 %  0.064 % 1952.0 2684
custom 7.463 %   0.003 %  0.002 % 5.0 67
Medivere 100 %   0.004 %  0.002 % 7.0 7
CerbaLab 66.667 %   0.011 %  0.005 % 2.0 3
Thryve 79.313 %   0.018 %  0.059 % 1246.0 1571

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Data Contradictions β€” Limits of Certainity

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General Substance Specific Substance Effect
Amino Acid and similar maltitol 1 Studies recorded. The consensus is Increases👶, Click for details.
Antibiotics, Antivirals etc azithromycin,(antibiotic)s[CFS] 1 Studies recorded. The consensus is Decreases👶, Click for details.
Antibiotics, Antivirals etc metronidazole (antibiotic)s[CFS] 1 Studies recorded. The consensus is Increases👶, Click for details.
Diet Style whole grain diet 2 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings) alcoholic beverages 1 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings) low-sugar 1 Studies recorded. The consensus is Increases📓, Click for details.
Food (excluding seasonings) oats 1 Studies recorded. The consensus is Increases👶, Click for details.
Herb or Spice Sumac(Rhus coriaria) 2 Studies recorded. The consensus is Decreases👶👪, Click for details.
Prebiotics and similar inulin (prebiotic) 1 Studies recorded. The consensus is Increases👶, Click for details.
Probiotics bacillus subtilis,lactobacillus acidophilus (probiotics) 1 Studies recorded. The consensus is Increases👶, Click for details.
Probiotics bifidobacterium animalis lactis (probiotics) 1 Studies recorded. The consensus is Decreases👶, Click for details.
Probiotics lactobacillus fermentum (probiotics) 1 Studies recorded. The consensus is Increases👶, Click for details.
Probiotics lactobacillus gasseri (probiotics) 2 Studies recorded. The consensus is Increases👶👪, Click for details.
Probiotics lactobacillus reuteri (probiotics) 1 Studies recorded. The consensus is Increases👶, Click for details.
Probiotics lactobacillus rhamnosus (probiotics) 1 Studies recorded. The consensus is Decreases📓, Click for details.
Sugar and similar saccharin 2 Studies recorded. The consensus is Decreases👶👪, Click for details.
Sugar and similar sugar 1 Studies recorded. The consensus is Decreases👶, Click for details.
Vitamins, Minerals and similar zinc 2 Studies recorded. The consensus is Decreases👶👪, Click for details.

All suggestions are computed solely on their predicted microbiome impact. Safety, side-effects etc must be evaluated by your medical professionals before starting. Some items suggests have significant risk of adverse consequences for some people.

Special thanks to David F Morrison and Geert Van Houcke for doing Quality Assurance. Special thanks to Oliver Luk, B.Sc. (Biology) from BiomeSight for spot checking the coding of data from the US National Library of Medicine

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