Actinomycetota Details: NCBI 201174, high G+C gram-positive [phylum]

| Actinobacteraeota| Actinobacteraeota Oren et al. 2015| Actinobacteria| Actinobacteriota

  1. Probiotic Effects:

    • Some Actinobacteria, such as Bifidobacterium species, are commonly used as probiotics. These bacteria are known for their beneficial effects on gut health. They contribute to the fermentation of dietary fibers, produce short-chain fatty acids (SCFAs), and help maintain a balanced and healthy gut microbiota.
  2. Short-Chain Fatty Acid Production:

    • Actinobacteria, particularly certain species in the human gut, contribute to the production of SCFAs, including acetate, propionate, and butyrate. SCFAs play a role in supporting gut health, providing energy for colonocytes, and influencing the immune system.
  3. Immunomodulation:

    • Some Actinobacteria may modulate the immune system. For example, Bifidobacterium species have been associated with anti-inflammatory effects and immune system regulation. This immunomodulatory activity is important for maintaining a balanced immune response in the gut.
  4. Metabolism of Complex Carbohydrates:

    • Actinobacteria in the gut are involved in the metabolism of complex carbohydrates, contributing to the breakdown of dietary fibers and the production of beneficial metabolites.
  5. Vitamin Synthesis:

    • Certain Actinobacteria are involved in the synthesis of vitamins, such as B vitamins (e.g., B12 and folate). These vitamins are essential for various physiological processes in the body.
  6. Antimicrobial Activity:

    • Some Actinobacteria produce secondary metabolites with antimicrobial properties. These compounds may help protect against the growth of harmful bacteria and contribute to the overall balance of the microbial community.
  7. Soil Bacteria and Human Health:

    • Actinobacteria are abundant in soil, and exposure to these bacteria in the environment may have indirect health effects. Some Actinobacteria-derived compounds are used in the production of antibiotics and other pharmaceuticals.

Visuals of Interactions with other bacteria of the same rank

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Statistics NCBI Data Punk End Products Produced

Lab Reporting

Different labs use different software to read the sample. See this post for more details.
One lab may say you have none, another may say you have a lot! - This may be solely due to the software they are using to estimate.
We deem lab specific values using values from the KM method for each specific lab to be the most reliable.

Desired Levels Suggestions for Actinomycetota

These are values that are computed from lab specific samples (Patent Pending)
LabFrequencyUD-LowUD-HighKM LowKM HighLab LowLab HighMean MedianStandard DeviationBox Plot LowBox Plot High KM Percentile Low KM Percentile High
Other Labs 8.08 0 0 10 930600 0 218464 38781.3 12140 91674.8 0 66700 0 %ile 100 %ile
biomesight 93.5 140 18120 260 97129 0 98363 15032.1 3950 42515.6 0 21410 4.6 %ile 97.7 %ile
thorne 100 11127 387999 0 222846 65947 43721 80050.5 0 89285 0 %ile 100 %ile
thryve 100 644 70499 255 888586 0 216932 38521.9 11006 91025.5 0 53585 3.3 %ile 100 %ile
ubiome 100 10335 128832 9591 679029 0 207098 65262.9 44156 72365.1 0 113728 7.4 %ile 100 %ile

External Reference Ranges for Actinomycetota

Actinomycetota (NCBI 201174) per million
Source of Ranges Low Boundary High Boundary Low Boundary %age High Boundary %age
XenoGene 0 30000 0 3
Nirvana/CosmosId 1000 12600 0.1 1.26
Thorne (20/80%ile) 1171.2 16166 0.1171 1.6166
GanzImmun Diagostics 3000 16000 0.3 1.6
Lab Teletest 10000 200000 1 20
Medivere 11000 50000 1.1 5
Jason Hawrelak 20000000 480000000 2000 48000
Statistic by Lab Source for Actinomycetota
These desired values are reported from the lab reports
Lab Frequency Seen Average Standard Deviation Sample Count Lab Samples
AmericanGut 100 %   2.643 %  6.431 % 15.0 15
BiomeSight 99.811 %   1.301 %  3.756 % 3174.0 3180
BiomeSightRdp 100 %   0.207 %  0.646 % 31.0 31
bugspeak 100 %   1.037 %  % 1.0 1
CerbaLab 100 %   6.893 %  6.334 % 3.0 3
CosmosId 100 %   4.137 %  6.339 % 32.0 32
custom 89.706 %   2.487 %  2.928 % 61.0 68
es-xenogene 100 %   2.267 %  9.742 % 29.0 29
GanzimmunDiag 100 %   2.058 %  0 % 3.0 3
Medivere 100 %   1.691 %  2.061 % 7.0 7
Microba 92.857 %   6.154 %  17.916 % 26.0 28
Microba1 100 %   0.06 %  % 1.0 1
SequentiaBiotech 100 %   5.682 %  6.962 % 36.0 36
Thorne 98.387 %   3.567 %  5.501 % 122.0 124
Thryve 100 %   3.524 %  8.382 % 1411.0 1411
Tiny 100 %   6.393 %  3.7 % 2.0 2
uBiome 100 %   6.528 %  7.236 % 789.0 789
vitract 100 %   0.513 %  0.135 % 6.0 6

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Data Contradictions β€” Limits of Certainity

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General Substance Specific Substance Effect
Amino Acid and similar Conjugated Linoleic Acid 2 Studies recorded. The consensus is Increases👶, Click for details.
Amino Acid and similar l-glutamic acid 1 Studies recorded. The consensus is Increases👶, Click for details.
Amino Acid and similar l-glutamine 2 Studies recorded. The consensus is Decreases👶, Click for details.
Amino Acid and similar l-taurine 1 Studies recorded. The consensus is Increases👶, Click for details.
Amino Acid and similar Tryptophan 1 Studies recorded. The consensus is Increases👪, Click for details.
Antibiotics, Antivirals etc macrolide ((antibiotic)s) 1 Studies recorded. The consensus is Decreases👶, Click for details.
Antibiotics, Antivirals etc minocycline (antibiotic)s[CFS] 1 Studies recorded. The consensus is Increases👶, Click for details.
Antibiotics, Antivirals etc penicillin-moxalactam (antibiotic)s 1 Studies recorded. The consensus is Increases👶, Click for details.
Antibiotics, Antivirals etc piperacillin-tazobactam (antibiotic)s 1 Studies recorded. The consensus is Increases👶, Click for details.
Antibiotics, Antivirals etc trimethoprim (antibiotic)s 1 Studies recorded. The consensus is Decreases👶, Click for details.
Common Supplements Exercise 1 Studies recorded. The consensus is Decreases👶, Click for details.
Common Supplements quercetin 1 Studies recorded. The consensus is Decreases👶, Click for details.
Common Supplements sodium butyrate 1 Studies recorded. The consensus is Decreases👶, Click for details.
Common Supplements Tributyrin 1 Studies recorded. The consensus is Decreases👶, Click for details.
Diet Style avocado peel 1 Studies recorded. The consensus is Increases👶, Click for details.
Diet Style high sugar diet 1 Studies recorded. The consensus is Increases👶, Click for details.
Diet Style high-fat diets 3 Studies recorded. The consensus is Decreases👶, Click for details.
Diet Style high-saturated fat diet 1 Studies recorded. The consensus is Decreases👶, Click for details.
Diet Style ketogenic diet 1 Studies recorded. The consensus is Increases👶, Click for details.
Diet Style low fodmap diet 2 Studies recorded. The consensus is Decreases👶, Click for details.
Diet Style low protein diet 1 Studies recorded. The consensus is Increases👶, Click for details.
Drug or "Non-drug" Methylene blue 1 Studies recorded. The consensus is Decreases👶, Click for details.
flavonoids, polyphenols etc Apigenin 1 Studies recorded. The consensus is Increases👶, Click for details.
flavonoids, polyphenols etc Coenzyme Q10 1 Studies recorded. The consensus is Increases👶, Click for details.
flavonoids, polyphenols etc luteolin (flavonoid) 1 Studies recorded. The consensus is Decreases👶, Click for details.
flavonoids, polyphenols etc quebracho 1 Studies recorded. The consensus is Increases👶, Click for details.
flavonoids, polyphenols etc resveratrol (grape seed/polyphenols/red wine) 1 Studies recorded. The consensus is Decreases👶, Click for details.
flavonoids, polyphenols etc Xanthohumol 2 Studies recorded. The consensus is Decreases👶, Click for details.
Food (excluding seasonings) alcoholic beverages 1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings) Astragalus 1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings) barley 1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings) fish oil 1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings) Goji (berry,juice) 1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings) Nicotine, Nicotine Patch 2 Studies recorded. The consensus is Increases👶👪, Click for details.
Food (excluding seasonings) pomegranate 1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings) Soymilk 1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings) walnuts 1 Studies recorded. The consensus is Increases👶, Click for details.
Food (excluding seasonings) Whole Cow milk 1 Studies recorded. The consensus is Increases👶, Click for details.
Herb or Spice berberine 2 Studies recorded. The consensus is Decreases👶, Click for details.
Herb or Spice camellia 1 Studies recorded. The consensus is Increases👶, Click for details.
Herb or Spice Moringa Oleifera 2 Studies recorded. The consensus is Decreases👶, Click for details.
Herb or Spice oregano (origanum vulgare, oil) | 1 Studies recorded. The consensus is Increases👶, Click for details.
Herb or Spice Rhubarb Peony Decoction 1 Studies recorded. The consensus is Increases👶, Click for details.
Miscellaneous, food additives, and other odd items bile (acid/salts) 1 Studies recorded. The consensus is Decreases👶, Click for details.
Miscellaneous, food additives, and other odd items Bismuth Salts 1 Studies recorded. The consensus is Decreases👶, Click for details.
Miscellaneous, food additives, and other odd items gallic acid (food additive) 1 Studies recorded. The consensus is Increases👶, Click for details.
Miscellaneous, food additives, and other odd items smoking 1 Studies recorded. The consensus is Decreases👶, Click for details.
Prebiotics and similar chitooligosaccharides (prebiotic) 1 Studies recorded. The consensus is Decreases👶, Click for details.
Prebiotics and similar fructo-oligosaccharides (prebiotic) 1 Studies recorded. The consensus is Increases👶, Click for details.
Prebiotics and similar Human milk oligosaccharides (prebiotic, Holigos, Stachyose) 2 Studies recorded. The consensus is Decreases👶, Click for details.
Prebiotics and similar inulin (prebiotic) 2 Studies recorded. The consensus is Increases👶, Click for details.
Prebiotics and similar resistant starch 1 Studies recorded. The consensus is Increases👶, Click for details.
Prescription - Other fenbendazole,(prescription) 1 Studies recorded. The consensus is Decreases👶, Click for details.
Prescription - Other helminth infection (prescription) 1 Studies recorded. The consensus is Increases👶, Click for details.
Prescription - Other polymannuronic acid 1 Studies recorded. The consensus is Increases👶, Click for details.
Probiotics bacillus coagulans (probiotics) 1 Studies recorded. The consensus is Increases👶, Click for details.
Probiotics bacillus subtilis (probiotics) 2 Studies recorded. The consensus is Decreases👶, Click for details.
Probiotics bifidobacterium bifidum (probiotics) 1 Studies recorded. The consensus is Increases👶, Click for details.
Probiotics bifidobacterium longum (probiotics) 1 Studies recorded. The consensus is Increases👶, Click for details.
Probiotics lactobacillus paracasei (probiotics) 1 Studies recorded. The consensus is Increases👶, Click for details.
Probiotics lactobacillus plantarum (probiotics) 2 Studies recorded. The consensus is Increases👶, Click for details.
Probiotics lactobacillus sakei (probiotics) 2 Studies recorded. The consensus is Increases👶, Click for details.
Probiotics Prescript Assist (2018 Formula) 1 Studies recorded. The consensus is Increases👶, Click for details.
Probiotics saccharomyces boulardii (probiotics) 1 Studies recorded. The consensus is Increases👶, Click for details.
Sugar and similar chitosan,(sugar) 1 Studies recorded. The consensus is Decreases👶, Click for details.
Sugar and similar lactulose 1 Studies recorded. The consensus is Increases👶, Click for details.
Sugar and similar non-starch polysaccharides 2 Studies recorded. The consensus is Increases👶, Click for details.
Vitamins, Minerals and similar selenium 1 Studies recorded. The consensus is Increases👶, Click for details.
Vitamins, Minerals and similar vitamin a 1 Studies recorded. The consensus is Increases👶, Click for details.
Vitamins, Minerals and similar vitamin b2,Riboflavin 1 Studies recorded. The consensus is Increases👶, Click for details.
Vitamins, Minerals and similar vitamin B7, biotin 2 Studies recorded. The consensus is Increases👶, Click for details.
Vitamins, Minerals and similar Vitamin C (ascorbic acid) 1 Studies recorded. The consensus is Increases👶, Click for details.
Vitamins, Minerals and similar vitamin d 3 Studies recorded. The consensus is Increases👶, Click for details.
Vitamins, Minerals and similar Vitamin E 1 Studies recorded. The consensus is Increases👶, Click for details.

Foods Containing the Actinomycetota bacteria

Data comes from FoodMicrobionet. For the meaning of weight, see that site. The bacteria does not need to be alive to have an effect.

Livarot (French Cheese) Weight: 0.4057 Firm/semi-hard cheese (Gouda and Edam type), caciotta Weight: 0.1083 Piedmont hard cheese Weight: 0.1064 Jarlsberg cheese Weight: 0.07494 Malaysian fermented fish sauce Weight: 0.0721 Campo das Vertentes cheese Weight: 0.04221 Brie cheese Weight: 0.03722 Korean soy sauce Choongju ganjang 180-4 1 Weight: 0.03397 Caipira cheese Weight: 0.03114 Arax cheese Weight: 0.03062 Serrano cheese, cow milk Weight: 0.0295 Canastra cheese, cow milk Weight: 0.02835 Beer Sour Flanders Red Ale Weight: 0.02761 Passito wine Weight: 0.0215 Butter cheese, cow milk Weight: 0.01952 Sausage, Cyprus: Limassol Weight: 0.01244 Serro cheese, cow milk Weight: 0.01142 Colonial cheese, cow milk Weight: 0.008547 Portuguese Painho de Porco Iberico fermented sausages Weight: 0.008181 Curd cheese, cow milk Weight: 0.007432 Sausage, Cyprus: Paphos Weight: 0.007256 Ham fermented for 4 years Weight: 0.005044 Lard Farm Weight: 0.004736 yoghurt fermentation Weight: 0.004625 Swiss-Dutch-type cheese Weight: 0.003232 Cerrado cheese, cow milk Weight: 0.00256

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