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Antihistaminic Effects: Pheniramine maleate blocks the action of histamine, a chemical released by the body during allergic reactions. By inhibiting histamine receptors, it helps alleviate allergy symptoms such as itching, sneezing, and nasal congestion.
Relief of Allergic Rhinitis: Pheniramine maleate is commonly used to relieve symptoms of allergic rhinitis, including nasal congestion, runny nose, itching, and sneezing caused by environmental allergens such as pollen, dust mites, and pet dander.
Management of Urticaria (Hives): Pheniramine maleate can be effective in the treatment of urticaria, a skin condition characterized by the sudden appearance of itchy, raised welts (hives) on the skin. It helps reduce itching and inflammation associated with hives.
Symptomatic Relief of Insect Bites and Stings: Pheniramine maleate can provide symptomatic relief from itching and swelling caused by insect bites and stings, including those from mosquitoes, bees, and wasps.
Treatment of Allergic Conjunctivitis: Pheniramine maleate eye drops are used to relieve symptoms of allergic conjunctivitis, such as redness, itching, and watering of the eyes caused by allergens such as pollen, dust, or pet dander.
Management of Mild Allergic Reactions: Pheniramine maleate may be used to manage mild allergic reactions, such as those caused by exposure to certain foods, medications, or other allergens, when immediate medical attention is not required.
Sedative Effects: Pheniramine maleate has sedative properties and may cause drowsiness or sleepiness, especially when taken at higher doses. This effect can be beneficial for individuals experiencing allergies that interfere with sleep but may impair alertness and coordination in some individuals.
Dry Mouth and Urinary Retention: Common side effects of pheniramine maleate include dry mouth and urinary retention (difficulty urinating). These effects are due to its anticholinergic properties and are more common in older adults.
Gastrointestinal Effects: Pheniramine maleate may cause gastrointestinal side effects such as nausea, vomiting, or constipation in some individuals.
Central Nervous System Effects: In addition to sedation, pheniramine maleate may cause other central nervous system effects such as dizziness, confusion, or headache, particularly at higher doses.
Drug Interactions: Pheniramine maleate may interact with other medications, including other antihistamines, sedatives, or medications with anticholinergic properties, leading to additive effects on sedation or other side effects. Patients should inform their healthcare provider about all medications they are taking.
| Rank | Probiotic | Impact |
|---|---|---|
| species | Escherichia coli | Reduces |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
| Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
|---|---|---|---|
| Abdominal Aortic Aneurysm | 0 | 0 | |
| ADHD | 0.4 | 0.1 | 3 |
| Age-Related Macular Degeneration and Glaucoma | 0.1 | 0.1 | |
| Allergic Rhinitis (Hay Fever) | 0.1 | 0.1 | |
| Allergies | 0.2 | 0.5 | -1.5 |
| Allergy to milk products | 0.4 | 0.1 | 3 |
| Alopecia (Hair Loss) | 0 | 0 | |
| Alzheimer's disease | 0.4 | 0.7 | -0.75 |
| Amyotrophic lateral sclerosis (ALS) Motor Neuron | 0.2 | 0.3 | -0.5 |
| Ankylosing spondylitis | 0.2 | 0.2 | 0 |
| Anorexia Nervosa | 0.4 | -0.4 | |
| Antiphospholipid syndrome (APS) | 0.4 | 0 | 0 |
| Asthma | 0.1 | -0.1 | |
| Atherosclerosis | 0.2 | 0.3 | -0.5 |
| Atrial fibrillation | 0.5 | 0.1 | 4 |
| Autism | 0.7 | 0.6 | 0.17 |
| Barrett esophagus cancer | 0 | 0 | |
| benign prostatic hyperplasia | 0.1 | 0.1 | |
| Bipolar Disorder | 0.3 | 0.5 | -0.67 |
| Brain Trauma | 0.1 | -0.1 | |
| Carcinoma | 0.4 | 0.3 | 0.33 |
| Celiac Disease | 0.1 | 0.3 | -2 |
| Cerebral Palsy | 0 | 0.4 | 0 |
| Chronic Fatigue Syndrome | 0.4 | 0.5 | -0.25 |
| Chronic Kidney Disease | 0.2 | 0.3 | -0.5 |
| Chronic Lyme | 0.1 | -0.1 | |
| Chronic Obstructive Pulmonary Disease (COPD) | 0.1 | 0.3 | -2 |
| Chronic Urticaria (Hives) | 0.2 | 0 | 0 |
| Coagulation / Micro clot triggering bacteria | 0.2 | 0.4 | -1 |
| Colorectal Cancer | 0.5 | 0.5 | |
| Constipation | 0.1 | 0.2 | -1 |
| Coronary artery disease | 0.2 | 0.2 | 0 |
| COVID-19 | 0.7 | 1.5 | -1.14 |
| Crohn's Disease | 0.7 | 0.6 | 0.17 |
| cystic fibrosis | 0.2 | 0.1 | 1 |
| deep vein thrombosis | 0.2 | 0.4 | -1 |
| Depression | 0.6 | 0.9 | -0.5 |
| Dermatomyositis | 0 | 0 | |
| Eczema | 0.1 | 0 | 0 |
| Endometriosis | 0.4 | 0.2 | 1 |
| Epilepsy | 0.1 | 0.1 | 0 |
| Fibromyalgia | 0.3 | 0.3 | 0 |
| Functional constipation / chronic idiopathic constipation | 0.6 | 0.4 | 0.5 |
| gallstone disease (gsd) | 0.3 | 0.1 | 2 |
| Gastroesophageal reflux disease (Gerd) including Barrett's esophagus | 0 | 0.1 | 0 |
| Generalized anxiety disorder | 0.2 | 0.1 | 1 |
| Glioblastoma | 0 | 0 | |
| Gout | 0.1 | -0.1 | |
| Graves' disease | 0 | 0.2 | 0 |
| Halitosis | 0 | 0 | 0 |
| Hashimoto's thyroiditis | 0.3 | 0 | 0 |
| Hidradenitis Suppurativa | 0 | 0 | |
| Histamine Issues,Mast Cell Issue, DAO Insufficiency | 0.2 | 0.1 | 1 |
| hyperglycemia | 0.1 | 0.1 | 0 |
| hypersomnia | 0.1 | -0.1 | |
| hypertension (High Blood Pressure | 0.3 | 0.4 | -0.33 |
| Hypothyroidism | 0.2 | -0.2 | |
| Hypoxia | 0 | 0 | |
| Inflammatory Bowel Disease | 0.3 | 1.3 | -3.33 |
| Insomnia | 0.1 | 0.1 | 0 |
| Intelligence | 0.1 | 0.1 | |
| Intracranial aneurysms | 0.3 | 0.3 | |
| Irritable Bowel Syndrome | 0.5 | 0.1 | 4 |
| Liver Cirrhosis | 0.6 | 0.5 | 0.2 |
| Long COVID | 0.5 | 1.1 | -1.2 |
| Low bone mineral density | 0.3 | -0.3 | |
| Lung Cancer | 0.1 | 0.3 | -2 |
| ME/CFS with IBS | 0 | 0.4 | 0 |
| ME/CFS without IBS | 0.1 | 0 | 0 |
| Metabolic Syndrome | 0.8 | 0.6 | 0.33 |
| Mood Disorders | 1 | 0.9 | 0.11 |
| multiple chemical sensitivity [MCS] | 0 | 0 | 0 |
| Multiple Sclerosis | 0.4 | 0.4 | 0 |
| Multiple system atrophy (MSA) | 0 | 0.3 | 0 |
| Neuropathy (all types) | 0.1 | 0.1 | 0 |
| neuropsychiatric disorders (PANDAS, PANS) | 0.1 | 0.1 | |
| Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | 0.1 | 0.5 | -4 |
| Obesity | 0.8 | 0.4 | 1 |
| obsessive-compulsive disorder | 0.8 | 0.3 | 1.67 |
| Osteoarthritis | 0.2 | 0.2 | 0 |
| Osteoporosis | 0.3 | 0.1 | 2 |
| pancreatic cancer | 0 | 0 | |
| Parkinson's Disease | 0.3 | 0.9 | -2 |
| Polycystic ovary syndrome | 0.3 | 0.6 | -1 |
| Postural orthostatic tachycardia syndrome | 0.1 | -0.1 | |
| Premenstrual dysphoric disorder | 0 | 0 | |
| Psoriasis | 0.4 | 0.3 | 0.33 |
| rheumatoid arthritis (RA),Spondyloarthritis (SpA) | 0.6 | 0.3 | 1 |
| Rosacea | 0.4 | 0.1 | 3 |
| Schizophrenia | 0.4 | 0.5 | -0.25 |
| scoliosis | 0.1 | 0.3 | -2 |
| Sjögren syndrome | 0.1 | 0.1 | 0 |
| Sleep Apnea | 0.4 | 0.3 | 0.33 |
| Small Intestinal Bacterial Overgrowth (SIBO) | 0.1 | 0.1 | |
| Stress / posttraumatic stress disorder | 0.2 | 0.3 | -0.5 |
| Systemic Lupus Erythematosus | 0.3 | 0.4 | -0.33 |
| Tic Disorder | 0.2 | 0.2 | |
| Tourette syndrome | 0 | 0 | |
| Type 1 Diabetes | 0.5 | 0.1 | 4 |
| Type 2 Diabetes | 0.8 | 0.7 | 0.14 |
| Ulcerative colitis | 0.2 | 0.3 | -0.5 |
| Unhealthy Ageing | 0.3 | 0.3 | 0 |
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