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Collagen Production: L-Proline is a key component of collagen, the most abundant protein in the human body. Collagen provides structural support to tissues, including skin, bones, cartilage, tendons, and blood vessels. Adequate proline levels are essential for collagen synthesis, wound healing, and maintaining the integrity and elasticity of connective tissues. Proline supplementation may support skin health, joint function, and overall tissue repair.
Wound Healing: Proline is involved in the synthesis of new tissue during the wound healing process. It plays a crucial role in collagen formation, which is necessary for repairing damaged tissues and promoting the closure of wounds. Proline supplements may help enhance the body's natural healing mechanisms and accelerate wound healing in individuals with injuries or surgical wounds.
Cardiovascular Health: L-Proline is involved in the synthesis of proline-rich proteins found in arterial walls and heart muscle. These proteins contribute to the structural integrity of blood vessels and the heart. Proline may help maintain cardiovascular health by supporting the integrity and elasticity of blood vessels, reducing the risk of arterial stiffness, hypertension, and cardiovascular diseases.
Muscle Health: Proline is essential for muscle repair and maintenance. It contributes to the formation of collagen and other proteins that support muscle structure and function. Adequate proline levels are necessary for muscle tissue regeneration after exercise-induced damage and for preventing muscle wasting associated with aging or certain medical conditions.
Skin Health: Collagen, which contains proline, is essential for maintaining skin elasticity, hydration, and firmness. Proline supplementation may help improve skin health and appearance by supporting collagen synthesis and reducing the signs of aging, such as wrinkles, fine lines, and sagging skin. Some studies suggest that proline may also have antioxidant properties, which can protect skin cells from oxidative damage caused by environmental factors and UV radiation.
Bone Health: Collagen is a major component of bone tissue, contributing to its strength, flexibility, and resilience. Proline plays a crucial role in collagen formation and bone mineralization, which are essential for maintaining bone density and preventing osteoporosis and fractures. Proline supplementation may support bone health and reduce the risk of bone-related disorders.
Rank | Probiotic | Impact |
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We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
---|---|---|---|
Allergic Rhinitis (Hay Fever) | 0.4 | -0.4 | |
Allergies | 0.6 | 0.6 | 0 |
Allergy to milk products | 0.8 | 0.4 | 1 |
Alzheimer's disease | 1 | -1 | |
Amyotrophic lateral sclerosis (ALS) Motor Neuron | 0.6 | 1.2 | -1 |
Ankylosing spondylitis | 1 | 1.2 | -0.2 |
Anorexia Nervosa | 0.6 | -0.6 | |
Antiphospholipid syndrome (APS) | 0.4 | -0.4 | |
Asthma | 0.6 | 0.6 | 0 |
Atrial fibrillation | 0.8 | 1 | -0.25 |
Autism | 1.4 | 1.4 | 0 |
benign prostatic hyperplasia | 0.4 | -0.4 | |
Bipolar Disorder | 0.6 | -0.6 | |
Brain Trauma | 0.8 | -0.8 | |
Carcinoma | 0.4 | -0.4 | |
Celiac Disease | 0.6 | 0.6 | 0 |
Chronic Fatigue Syndrome | 0.4 | -0.4 | |
Chronic Kidney Disease | 0.4 | -0.4 | |
Chronic Lyme | 0.6 | -0.6 | |
Chronic Urticaria (Hives) | 0.2 | -0.2 | |
Coagulation / Micro clot triggering bacteria | 0.8 | -0.8 | |
Colorectal Cancer | 1.4 | -1.4 | |
Constipation | 1.2 | -1.2 | |
COVID-19 | 1.2 | -1.2 | |
Crohn's Disease | 0.4 | 1.6 | -3 |
cystic fibrosis | 0.4 | -0.4 | |
deep vein thrombosis | 0.8 | -0.8 | |
Depression | 0.6 | 1.2 | -1 |
Eczema | 1 | -1 | |
Endometriosis | 1 | -1 | |
Epilepsy | 0.6 | -0.6 | |
Functional constipation / chronic idiopathic constipation | 1.2 | -1.2 | |
gallstone disease (gsd) | 0.4 | -0.4 | |
Generalized anxiety disorder | 0.4 | -0.4 | |
Graves' disease | 0.6 | 0.6 | |
Hashimoto's thyroiditis | 0.2 | 0.2 | |
Histamine Issues,Mast Cell Issue, DAO Insufficiency | 0.2 | -0.2 | |
hyperglycemia | 0.4 | -0.4 | |
hypersomnia | 0.2 | -0.2 | |
hypertension (High Blood Pressure | 0.2 | 0.6 | -2 |
IgA nephropathy (IgAN) | 0.6 | -0.6 | |
Inflammatory Bowel Disease | 0.2 | 0.8 | -3 |
Irritable Bowel Syndrome | 0.4 | 1.4 | -2.5 |
Liver Cirrhosis | 1.4 | -1.4 | |
Long COVID | 1 | 1.8 | -0.8 |
Lung Cancer | 0.4 | -0.4 | |
Metabolic Syndrome | 1.2 | -1.2 | |
Mood Disorders | 1.2 | 1.2 | 0 |
myasthenia gravis | 0.6 | 0.6 | |
Neuropathy (all types) | 0.2 | 0.2 | |
Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | 1.2 | -1.2 | |
Obesity | 1.4 | -1.4 | |
obsessive-compulsive disorder | 1.2 | -1.2 | |
Osteoarthritis | 0.2 | -0.2 | |
Osteoporosis | 0.4 | -0.4 | |
Parkinson's Disease | 0.6 | 0.8 | -0.33 |
Polycystic ovary syndrome | 1 | -1 | |
Postural orthostatic tachycardia syndrome | 0.6 | -0.6 | |
rheumatoid arthritis (RA),Spondyloarthritis (SpA) | 0.2 | 1.6 | -7 |
Rosacea | 0.2 | 0.2 | |
Schizophrenia | 0.6 | 0.2 | 2 |
Sjögren syndrome | 0.4 | -0.4 | |
Sleep Apnea | 0.8 | -0.8 | |
Small Intestinal Bacterial Overgrowth (SIBO) | 1 | -1 | |
Stress / posttraumatic stress disorder | 0.8 | -0.8 | |
Systemic Lupus Erythematosus | 1.2 | -1.2 | |
Type 1 Diabetes | 0.2 | -0.2 | |
Type 2 Diabetes | 1.2 | -1.2 | |
Ulcerative colitis | 0.4 | 1.4 | -2.5 |
Unhealthy Ageing | 0.6 | -0.6 |
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