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Antioxidant Activity: Pterostilbene exhibits strong antioxidant properties, meaning it can neutralize harmful free radicals in the body. Free radicals are molecules that can cause oxidative damage to cells and contribute to aging and various diseases. By scavenging free radicals, pterostilbene helps to protect cells from oxidative stress and reduce the risk of oxidative damage to tissues throughout the body.
Cardiovascular Health: Pterostilbene may have beneficial effects on cardiovascular health. It helps to improve endothelial function, reduce inflammation in blood vessels, and inhibit the formation of blood clots. Pterostilbene may also help to lower cholesterol levels and blood pressure, reducing the risk of cardiovascular diseases such as atherosclerosis, hypertension, and heart disease.
Neuroprotective Effects: Pterostilbene has been studied for its potential neuroprotective effects in the brain. It helps to protect neurons from oxidative damage, reduce inflammation, and modulate signaling pathways involved in neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. Pterostilbene may also help to improve cognitive function and memory.
Anti-inflammatory Effects: Pterostilbene has been shown to possess anti-inflammatory properties, meaning it can reduce inflammation in the body. Chronic inflammation is associated with the development and progression of various diseases, including cardiovascular disease, neurodegenerative diseases, and cancer. By inhibiting inflammatory pathways and reducing the production of inflammatory molecules, pterostilbene may help to alleviate symptoms and slow the progression of these diseases.
Cancer Prevention: Pterostilbene has been investigated for its potential anti-cancer properties. It helps to inhibit the growth of cancer cells, induce apoptosis (programmed cell death), and prevent the spread of cancerous tumors. Pterostilbene may also help to reduce the risk of cancer by modulating signaling pathways involved in cell growth, proliferation, and survival. It has been studied in various types of cancer, including breast, prostate, lung, colon, and skin cancer.
Metabolic Health: Pterostilbene has been studied for its potential benefits in improving metabolic health and preventing obesity and type 2 diabetes. It helps to regulate glucose metabolism, improve insulin sensitivity, and reduce lipid accumulation in adipose tissue and the liver. Pterostilbene may also help to suppress appetite and promote weight loss.
| Rank | Probiotic | Impact |
|---|---|---|
| species | Akkermansia muciniphila | Increases |
We extend modifiers to include items that changes the parent and child taxa. I.e. for a species, that would be the genus that is belongs to and the strains in the species.
| Taxonomy | Rank | Effect | Citations | Notation |
|---|---|---|---|---|
| Erysipelotrichaceae | family | Increases | 👪 Source Study | |
| Akkermansiaceae | family | Increases | 👪 Source Study | |
| Akkermansia | genus | Increases | 📓 Source Study | |
| Erysipelatoclostridium | genus | Increases | 📓 Source Study | |
| environmental samples | no rank | Increases | 👶 Source Study | |
| unclassified Akkermansia | no rank | Increases | 👶 Source Study | |
| unclassified Erysipelatoclostridium | norank | Increases | 👶 Source Study | |
| Akkermansia glycaniphila | species | Increases | 👶 Source Study | |
| Akkermansia muciniphila | species | Increases | 👶 Source Study | |
| Chlamydiae/Verrucomicrobia group | superphylum | Increases | ⚗️ Source Study |
A higher number indicates impact on more bacteria associated with the condition and confidence on the impact.
We have X bacteria high and Y low reported. We find that the modifier reduces some and increases other of these two groups. We just tally: X|reduces + Y|Increase = Positive X|increases + Y|decrease = Negative.
Benefit Ratio:
Numbers above 0 have increasing positive effect.
Numbers below 0 have increasing negative effect.
| Condition | Positive Impact | Negative Impact | Benefit Ratio Impact |
|---|---|---|---|
| Allergies | 0.2 | 0.2 | 0 |
| Alopecia (Hair Loss) | 0.2 | -0.2 | |
| Alzheimer's disease | 0.2 | 0.8 | -3 |
| Amyotrophic lateral sclerosis (ALS) Motor Neuron | 0.2 | 0.8 | -3 |
| Asthma | 0.8 | 0.8 | |
| Atherosclerosis | 0.6 | 0.6 | |
| Autism | 1 | 1 | 0 |
| Barrett esophagus cancer | 0.2 | 0.2 | |
| Celiac Disease | 1.2 | 1.2 | |
| Cerebral Palsy | 0.6 | -0.6 | |
| Chronic Fatigue Syndrome | 0.6 | -0.6 | |
| Chronic Kidney Disease | 0.6 | -0.6 | |
| Chronic Urticaria (Hives) | 0.2 | 0.2 | |
| Colorectal Cancer | 0.2 | 0.8 | -3 |
| COVID-19 | 0.8 | 1 | -0.25 |
| Crohn's Disease | 0.6 | 0.6 | 0 |
| Depression | 0.8 | 1.1 | -0.38 |
| Epilepsy | 0.8 | 1.2 | -0.5 |
| Functional constipation / chronic idiopathic constipation | 0.2 | -0.2 | |
| Gout | 0.8 | -0.8 | |
| Graves' disease | 0.2 | -0.2 | |
| Hashimoto's thyroiditis | 0.6 | -0.6 | |
| hypercholesterolemia (High Cholesterol) | 0.4 | 0.4 | |
| hyperglycemia | 0.8 | 0.3 | 1.67 |
| Hyperlipidemia (High Blood Fats) | 0.6 | -0.6 | |
| hypertension (High Blood Pressure | 0.6 | 0.8 | -0.33 |
| Hypoxia | 0.6 | -0.6 | |
| Inflammatory Bowel Disease | 0.8 | 0.6 | 0.33 |
| Irritable Bowel Syndrome | 0.2 | 0.4 | -1 |
| Liver Cirrhosis | 1.2 | 0.6 | 1 |
| Long COVID | 0.2 | 1.4 | -6 |
| Lung Cancer | 0.2 | 0.2 | |
| Metabolic Syndrome | 1 | 0.8 | 0.25 |
| Mood Disorders | 0.8 | 1.3 | -0.63 |
| multiple chemical sensitivity [MCS] | 0.2 | 0.6 | -2 |
| Multiple Sclerosis | 0.8 | -0.8 | |
| Multiple system atrophy (MSA) | 0.8 | -0.8 | |
| Neuropathy (all types) | 0.6 | -0.6 | |
| neuropsychiatric disorders (PANDAS, PANS) | 0.2 | 0.2 | |
| Nonalcoholic Fatty Liver Disease (nafld) Nonalcoholic | 0.2 | 0.2 | 0 |
| Obesity | 1.4 | 1.1 | 0.27 |
| obsessive-compulsive disorder | 0.2 | 0.2 | |
| Osteoporosis | 0.4 | 0.4 | |
| Parkinson's Disease | 0.6 | 1.7 | -1.83 |
| Polycystic ovary syndrome | 0.6 | 0.2 | 2 |
| Psoriasis | 0.2 | 0.6 | -2 |
| rheumatoid arthritis (RA),Spondyloarthritis (SpA) | 0.2 | 0.8 | -3 |
| Schizophrenia | 0.2 | -0.2 | |
| Stress / posttraumatic stress disorder | 0.2 | 0.8 | -3 |
| Tourette syndrome | 0.6 | -0.6 | |
| Type 2 Diabetes | 0.8 | 0.6 | 0.33 |
| Ulcerative colitis | 0.8 | 0.8 | |
| Unhealthy Ageing | 0.6 | 0.6 |
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